Search clinical trials for: lung cancer with activated mTOR/PI3K pathway
Total 239266 results
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Emory UniversityNovartis PharmaceuticalsCompletedLung Cancer | Solid TumorsUnited States
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Deciphera Pharmaceuticals LLCRecruitingMelanoma | Non-Small Cell Lung Cancer | Advanced Solid Tumor | Pancreatic Ductal Adenocarcinoma | BRAF Gene Mutation | RAS Mutation | NF1 Mutation | RAF Mutation | CRAF Gene MutationUnited States
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Novartis PharmaceuticalsCompletedTumors With CDK4/6 Pathway ActivationUnited States
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National Cancer Institute (NCI)University of Chicago; City of Hope Medical Center; University of Southern California and other collaboratorsCompleted
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Assistance Publique Hopitaux De MarseilleRecruitingLung Cancer | Smoking-related Pathology | Atheroma | Non-progressive Cancer > 5 YearsFrance
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Tianjin Medical University Cancer Institute and...RecruitingNon-small Cell Lung Cancer | EGFR Activating Mutation | EGFR-TKI Resistant Mutation | Cell Cycle DeregulationChina
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Hoffmann-La RocheFoundation MedicineRecruitingMetastatic Lung Cancer | Metastatic Gastrointestinal CancerSpain, France, Italy, Netherlands, Germany
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Black Diamond Therapeutics, Inc.RecruitingMelanoma | Colorectal Cancer | NSCLC | Solid Tumor | Metastatic Lung Cancer | Metastatic Lung Non-Small Cell Carcinoma | Metastatic Melanoma | Non-small Cell Lung Cancer | Histiocytosis | Melanoma (Skin) | Recurrent Melanoma | Thyroid Carcinoma | Thyroid Cancer | Brain Metastases | Recurrent Histiocytic and Dendritic... and other conditionsUnited States
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Shaw Cancer CenterSteadman Philippon Research InstituteRecruitingRadiation Induced FibrosisUnited States
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Immuneering CorporationRecruitingPancreatic Adenocarcinoma | Advanced Solid Tumor | Non-small Cell Lung Cancer (NSCLC) | Malignant Melanoma (Cutaneous)United States
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Mirati Therapeutics Inc.RecruitingSolid Tumor | Non Small Cell Lung Cancer | Advanced Solid Tumor | Colo-rectal CancerUnited States, Puerto Rico
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Jazz PharmaceuticalsRecruitingSolid Tumor | Metastatic Cancer | Advanced CancerUnited States
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Navire Pharma Inc., a BridgeBio companyAmgenRecruitingNon Small Cell Lung Cancer | Metastatic Solid Tumor | Solid Tumor, Adult | Metastatic NSCLCSpain, Australia, France, Denmark, Greece, Italy, Netherlands
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Navire Pharma Inc., a BridgeBio companyBristol-Myers SquibbRecruitingSolid Tumor | Non Small Cell Lung CancerUnited States
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Stanford UniversityPatient-Centered Outcomes Research InstituteRecruitingComparative Effectiveness Trial of Two Supportive Cancer Care Delivery Models for Adults With CancerCancer | End of LifeUnited States
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Ikena OncologyRecruitingSolid Tumor | Solid Tumors, Adult | Malignant Pleural Mesothelioma (MPM) | Epithelioid Hemangioendothelioma (EHE) | NF2 Deficient Mesothelioma | Other NF2 Deficient Solid Tumors and Solid Tumors With YAP1/TAZ Fusion Genes | NF2 Deficiency | YAP1 or TAZ Gene FusionsUnited States, United Kingdom
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)RecruitingAdvanced Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | Metastatic Malignant Neoplasm in the Liver | Metastatic Malignant Neoplasm in the LungUnited States
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Sun Yat-sen UniversityRecruitingNon-small Cell Lung CancerChina
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Deciphera Pharmaceuticals LLCRecruitingNon-Small Cell Lung Cancer | Advanced Solid Tumor | Metastatic Solid TumorUnited States
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Second Affiliated Hospital of Guangzhou Medical...RecruitingHepatocellular Carcinoma | Solid Tumor, AdultChina
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MapKure, LLCRecruitingSolid Tumor | B-Raf Mutation-Related TumorsUnited States, Australia
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NanobiotixRecruitingMetastatic Renal Cell Carcinoma | Squamous Cell Carcinoma of Head and Neck | Radiotherapy | Immunotherapy | Microsatellite Instability-High Solid Malignant Tumour | Metastasis From Malignant Tumor of Liver | Metastasis From Malignant Tumor of Cervix | Metastasis From Malignant Melanoma of Skin (Disorder) and other conditionsUnited States
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Coherus Biosciences, Inc.Merck Sharp & Dohme LLC; Surface OncologyCompleted
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St. Jude Children's Research HospitalNovartis PharmaceuticalsCompletedGlioma | Neoplasms | Glioblastoma | Neoplasms, Neuroepithelial | Central Nervous System Neoplasms | Brain Cancer | Brain Tumor | Ependymoma | Medulloblastoma | Anaplastic Astrocytoma | Anaplastic Ganglioglioma | Anaplastic Ependymoma | Anaplastic Oligodendroglioma | Pineoblastoma | Recurrent Medulloblastoma | CNS Tumor | Pediatric... and other conditionsUnited States
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AstraZenecaActive, not recruitingLocally Advanced or Metastatic Non Small Cell Lung Cancer Stage IIIb - IVUnited States, Canada, France, Italy, Spain, United Kingdom, Belgium, Poland, Brazil, Germany, Hungary, Peru, Russian Federation, Turkey, Australia, Chile, Austria, Netherlands, Portugal, Israel, Mexico, Romania, Sweden, Ukraine, Bulgaria, Argenti...
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National Cancer Institute (NCI)Active, not recruitingAdvanced Malignant Solid Neoplasm | Refractory Malignant Solid Neoplasm | Recurrent Ewing Sarcoma | Recurrent Hepatoblastoma | Recurrent Histiocytic and Dendritic Cell Neoplasm | Recurrent Langerhans Cell Histiocytosis | Recurrent Malignant Germ Cell Tumor | Recurrent Malignant Solid Neoplasm | Recurrent... and other conditionsUnited States, Puerto Rico
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Technical University of MunichCompleted
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Trishula Therapeutics, Inc.AbbVieCompletedSolid Tumor, AdultUnited States, Korea, Republic of
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Memorial Sloan Kettering Cancer CenterCompletedSarcoma | Small Intestine Cancer | Ovarian Cancer | Lung Cancer | Brain and Central Nervous System Tumors | Metastatic Cancer | Neuroblastoma | Intraocular Melanoma | Melanoma (Skin) | RetinoblastomaUnited States
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Novartis PharmaceuticalsCompletedCarcinoma, Non-Small-Cell LungItaly, Spain, Germany, Japan, Taiwan, Belgium, Netherlands, Singapore, Argentina, France, Israel, Sweden, Korea, Republic of, Lebanon, United Kingdom, United States, Austria, Mexico, Norway, Russian Federation
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National Cancer Institute (NCI)Active, not recruitingUterine Cervical Neoplasms | Small Cell Lung Carcinoma | Ovarian Neoplasms | Carcinoma, Neuroendocrine | Extrapulmonary Small Cell Cancer | Carcinoma, Non-Small -Cell LungUnited States
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JS InnoPharm, LLCSuspended
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Duke UniversityNational Institute of Nursing Research (NINR); National Institutes of Health...Active, not recruitingChronic Kidney Diseases | Diabetes Mellitus, Type 1 | Systemic Lupus Erythematosus | Inflammatory Bowel Diseases | Cystic Fibrosis | Sickle Cell Disease | Stem Cell Transplant | Childhood Cancer | Organ TransplantUnited States
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Wake Forest University Health SciencesNational Cancer Institute (NCI)WithdrawnHead and Neck Cancer | Chronic Obstructive Pulmonary Disease | Lung CancerUnited States
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Turning Point Therapeutics, Inc.Active, not recruitingAdvanced Solid Tumor | Metastatic Solid Tumors | MET Gene AlterationsUnited States, France, Korea, Democratic People's Republic of, Korea, Republic of, Spain
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AstraZenecaCompletedLocally Advanced or Metastatic Non Small Cell Lung Cancer Stage IIIb - IVUnited States, Poland, France, Germany, Brazil, Hungary, Netherlands, Bulgaria
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Laurie McLouthNational Cancer Institute (NCI)Completed
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Trishula Therapeutics, Inc.CompletedLymphoma | Solid TumorUnited States
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xCuresCancer CommonsAvailableExpanded Access to Ulixertinib (BVD-523) in Patients With Advanced MAPK Pathway-Altered MalignanciesMelanoma | Head and Neck Cancer | Glioblastoma | Hepatocellular Carcinoma | Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Esophageal Cancer | Small Bowel Cancer | Ovarian Cancer | Non Small Cell Lung Cancer | Cholangiocarcinoma | Bladder Cancer | Thyroid Cancer | ERK Mutation | MAPK Gene Mutation | KRAS Activating... and other conditionsUnited States
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Erasca, Inc.CompletedAdvanced Non-squamous Non-small-cell Lung CancerUnited States
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Haihe Biopharma Co., Ltd.TerminatedMelanoma | Erdheim-Chester Disease | Non-Small-Cell Lung Cancer | Advanced Tumors | Other RAS/RAF/MEK/ERK Mutated TumorsUnited States, China
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National Cancer Centre, SingaporeNovartisCompleted
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H. Lee Moffitt Cancer Center and Research InstituteArray BioPharmaCompletedNon-Small Cell Lung Cancer | Lung CancerUnited States
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Centre Leon BerardCompletedSARS-CoV-2 (COVID-19) Infection | Advanced or Metastatic Hematological or Solid TumorFrance
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Fred Hutchinson Cancer CenterNational Cancer Institute (NCI); National Heart, Lung, and Blood Institute...CompletedChronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Adult Acute Myeloid Leukemia With Del(5q) | Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) | Adult Acute Myeloid Leukemia With t(16;16)(p13;q22) | Adult... and other conditionsUnited States
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Andrew SharabiPfizerTerminatedEarly Stage Non-Small Cell Lung CancerUnited States
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PfizerCompletedSolid Tumor and Hematologic MalignanciesUnited States
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Samsung Medical CenterCompleted
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Tumor Center RegensburgGerman Cancer AidCompletedQuality of Life | Breast Cancer | Breast NeoplasmsGermany
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Fuda Cancer Hospital, GuangzhouBenhealth Biopharmaceutical (Shenzhen) Co., Ltd.WithdrawnAdvanced Lung CancerChina