Search clinical trials for: major pathological response

Total 27473 results

Fifth Affiliated Hospital, Sun Yat-Sen University

Recruiting

The Efficacy and Safety of De-escalated Postoperative Radiotherapy in Locally Advanced HNSCC With pCR/MPR

Head and Neck Squamous Cell Carcinoma

China
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Guangdong Provincial People's Hospital; Third Affiliated Hospital, Sun Yat-Sen...

Recruiting

Neoadjuvant Camrelizumab, Nab-paclitaxel and Carboplatin in Stage IB-IIIA NSCLC

Lung Cancer, Non-small Cell | Artificial Intelligence

China
Novartis Pharmaceuticals

Terminated

This Study Will Evaluate the Effect of Canakinumab or Pembrolizumab Given as Monotherapy or in Combination as Neo-adjuvant Treatment for Subjects With Early Stages NSCLC. (CANOPY-N)

Non-small Cell Lung Cancer

Canada, Netherlands, Spain, France, Japan, Russian Federation, Germany, Belgium, Greece, Turkey, Taiwan, United States
Catholic University of the Sacred Heart

Unknown

VSL#3 Versus Placebo in Increasing the Pathological Major Response Rate in Patients With Rectal Cancer

Rectal Cancer

Italy
Tang-Du Hospital

Recruiting

Mechanism Study to Investigate Difference in Efficacy of Neoadjuvant Chemoimmunotherapy in Lung Squamous Cell Carcinoma

Lung Squamous Cell Carcinoma | Neoadjuvant Chemoimmunotherapy | Tumor Microenvironment

China
Peking University People's Hospital
Akeso Pharmaceuticals, Inc.

Not yet recruiting

Neoadjuvant Cadonilimab Combined With Anlotinib in Locally Advanced Resectable Esophageal Squamous Cell Carcinoma

Locally Advanced Esophageal Squamous Cell Carcinoma
Instituto Nacional de Cancerologia de Mexico

Recruiting

Ceftolozane/Tazobactam vs. Piperacillin/Tazobactam for the Treatment of Bacteremia in Hemato-oncological Patients

Hematologic Neoplasms | Neutropenia

Mexico
Max-Planck-Institute of Psychiatry

Recruiting

Deep Phenotyping for Clinical Inferring Response in Treatment Resistant Depression (DECIDE)

Depressive; Disorder, Major, Single Episode, Major, With Psychotic Symptoms | Depressive; Disorder, Major, Single Episode, Major (Without Psychotic Symptoms) | Depressive Disorder, Major, Recurrent, With Psychotic Symptoms | Depressive Disorder, Major, Recurrent, Without Psychotic Symptoms and other conditions

Germany
The Hong Kong Polytechnic University
Health and Medical Research Fund

Recruiting

Intermittent Theta-burst Stimulation for Major Depression: an Intensity-response Study

Depression, Unipolar

Hong Kong
University of Nottingham
Biotechnology and Biological Sciences Research Council

Recruiting

Multi-organ Responses to CHronic Physical Activity and INactivity (CHAIN)

Metabolic Syndrome | Sedentary Behavior | Age-related Cognitive Decline | Age-Related Sarcopenia

United Kingdom
Bezmialem Vakif University

Recruiting

The Effect of Resolvins on the Resolve of Inflammatory Low Back Pain

Low Back Pain | Lumbar Disc Herniation | Inflammatory Response

Turkey
Clexio Biosciences Ltd.

Recruiting

A Study of CLE-100 (Oral Esketamine) as an Adjunctive Treatment to Standard Antidepressants for Major Depressive Disorder (SOLEO)

Adjunctive Treatment of Major Depressive Disorder (MDD)

United States
Bioscience Cosmetics SL
Eurofins

Not yet recruiting

Evaluation of the Safety and Efficacy of Hyaluronic Acid Injection in Labia Majora Augmentation

Vulvar Atrophy

France, Poland
Merck Sharp & Dohme LLC

Recruiting

A Study to Assess Efficacy and Safety of Pembrolizumab With or Without Sacituzumab Tirumotecan (MK- 2870) in Adult Participants With Resectable Non Small Cell Lung Cancer (NSCLC) Not Achieving Pathological Complete Response (pCR) (MK-2870-019)

Non Small Cell Lung Cancer

United States, Israel, Taiwan, Korea, Republic of, Switzerland, Hong Kong
Aswan University

Recruiting

Stellate Ganglion Block for Preserving Arteriovenous Fistula in Hemodialysis Patients Undergoing Major Lower Limb Orthopedic Surgery

Hemodialysis | Arteriovenous Fistula | Stellate Ganglion Block | Major Lower Limb Orthopedic Surgery

Egypt
Melanoma Institute Australia
Bristol-Myers Squibb

Not yet recruiting

Neoadjuvant Nivolumab and Relatlimab in Cutaneous Squamous Cell Carcinoma

Cutaneous Squamous Cell Carcinoma
Wuhan Union Hospital, China

Not yet recruiting

Deep Learning Model Predicts Pathological Complete Response of Lung Cancer Following Neoadjuvant Immunochemotherapy

Non-small Cell Lung Cancer | Pathological Complete Response | Neoadjuvant Chemoimmunotherapy | Deep Learning Model
Centre Hospitalier Universitaire de Besancon

Recruiting

Metabolomic and Immune Profiling in the Development of Pancreatic Fistulas After Cephalic Duodenopancreatectomy (PROMETHEE)

Pancreatic Fistula | Acute Pancreatitis

France
Regina Elena Cancer Institute

Recruiting

Tolerability and Efficacy of Adjuvant T-DM1 in Patients With HER2 Positive Breast Cancer After Incomplete Pathological Response to Neoadjuvant Chemotherapy Including Anti-HER2 Agents. Real-world Multicenter Retrospective-prospective Study (ATD)

Breast Cancer

Italy
Fondazione Policlinico Universitario Agostino Gemelli...

Recruiting

Transcriptional and Epimetabolic Profile of Breast Carcinoma With Luminal or HER2+ or Locally Advanced Triple-negative Histotype in Patients With/Without Previous Clinical History of Metabolic Syndrome (PROMETA)

Breast Cancer | Metabolic Syndrome

Italy
Lithuanian University of Health Sciences

Recruiting

The Relations Among Endotoxin, Inflammatory Cytokines, Cognitive Markers and Brain MRI Changes in Subjects With Depressive Disorder

Inflammation | Cognitive Dysfunction | Genetic Predisposition to Disease | Endotoxemia | Major Depressive Disorder | Blood Brain Barrier Defect

Lithuania
Princess Anna Mazowiecka Hospital, Warsaw, Poland
Medical University of Warsaw

Not yet recruiting

The High Initial Dose of Monitored Vitamin D Supplementation in Preterm Infants. (HIDVID)

Nephrolithiasis | Vitamin D Deficiency | Metabolic Bone Disease | Osteopenia of Prematurity | Late-Onset Neonatal Sepsis

Poland
Jiangxi Provincial Cancer Hospital

Recruiting

The Prognostic Value of the Degree of Pathological Response of Induction Chemotherapy for NPC

Nasopharyngeal Carcinoma | Tumor Microenvironment | Pathologic Complete Response

China
University of Central Florida
American College of Sports Medicine

Recruiting

Dose-Response Effect Exercise and Depression

Depression

United States
First Affiliated Hospital Xi'an Jiaotong University
Shaanxi Provincial People's Hospital; Henan Provincial People's Hospital; 521... and other collaborators

Not yet recruiting

Response of Intracardiac Thrombus to Anticoagulants in Patients With Non-valvular Atrial Fibrillation (LYSIS) (LYSIS)

Atrial Fibrillation | Intracardiac Thrombus

China
University Medical Center Groningen
Centre Hospitalier Universitaire de Nice; LungenClinic Grosshansdorf

Recruiting

Clinical Validation and Benchmarking of Top Performing ctDNA Diagnostics - Stage III NSCLC (MRD-LUNG)

Lung Cancer Stage III

France, Germany, Netherlands
Osijek University Hospital

Recruiting

Perioperative Adiponectin and Postoperative Inflammatory Response After Major Abdominal Surgery (ADIPOS)

Systemic Inflammatory Response Syndrome | Postoperative Complications | Surgery | Obesity, Abdominal

Croatia
Erasmus Medical Center

Not yet recruiting

Can we Use a Simple Blood Test to Reduce Unnecessary Adverse Effects From Radiotherapy by Timely Identification of Radiotherapy-resistant Rectal Cancers? MeD-Seq Rectal Study

Pathological Response Rate, Circulating Tumour DNA
Institut Cancerologie de l'Ouest

Not yet recruiting

Prediction in Silico of Pathological Response in a Prospective Cohort Study of Early Breast Cancer Patients (NEOEPICURE)

Breast Cancer

France
Centre Hospitalier Rouffach

Recruiting

Added Value of a Neuroendocrine Test Battery in the Response to Repetitive Transcranial Magnetic Stimulation (rTMS) Treatment (Endo-rTMS)

Major Depression

France
The First Affiliated Hospital with Nanjing Medical...

Recruiting

Omission of ALND in Breast Cancer Patients With Axillary pCR

Breast Cancer | Pathological Complete Response | Axillary Lymph Node Dissection | Neoadjuvant Systemic Therapy | Axillary Lymph

China
Institut Guttmann
University of Barcelona

Recruiting

Home-based Non-invasive Brain Stimulation for Treatment-resistant Depression Feasibility, Efficacy and Biomarker of Treatment Response

Major Depressive Disorder

Spain
Shanghai Pulmonary Hospital, Shanghai, China
Zunyi Medical College; Ningbo HwaMei Hospital, Zhejiang, China; The First Affiliated...

Recruiting

Deep Learning Signature for Predicting Complete Pathological Response to Neoadjuvant Chemoimmunotherapy in Non-small Cell Lung Cancer

Non-small Cell Lung Cancer | Neoadjuvant Chemoimmunotherapy | Complete Pathological Response

China
Maastricht University Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development

Recruiting

Optimizing Access Surgery In Senior Hemodialysis Patients (OASIS)

Hemodialysis Access Failure | Arteriovenous Fistula | Vascular Access Complication | Arteriovenous Graft | Dialysis Access Malfunction | Central Venous Catheter Related Bloodstream Infection

Netherlands
Yale University
National Institute of Mental Health (NIMH)

Recruiting

Alpha-Amino-3-Hydroxy-5-Methyl-4- Isoxazole Propionic Acid Receptor Components of the Anti-Depressant Ketamine Response

Bipolar Disorder | Depressive Disorder, Major | Post Traumatic Stress Disorder

United States
Centre hospitalier de l'Université de Montréal...

Recruiting

Identifying Predictors Of Response To Mepolizumab In CRSwNP (ISS-RESMEPO)

Chronic Rhinosinusitis With Nasal Polyps

Canada
Centre Hospitalier St Anne

Not yet recruiting

Prediction of the Therapeutic Response in Depression Based on Neuro-computational Modeling Assessment of Motivation (STRATIDEP)

Major Depressive Disorder

France
Assiut University

Recruiting

Single-stage Correction of Acute Angle Coxa Vara (Coxavara)

Coxa Vara

Egypt
Janssen Research & Development, LLC

Recruiting

A Study in Participants With Major Depressive Disorder (MDD) With Anhedonia and Inadequate Response to Current Antidepressant Therapy Including a Selective Serotonin Reuptake Inhibitor (SSRI) or Serotonin Norepinephrine Reuptake Inhibitor (SNRI) (VENTURA-RWE)

Depressive Disorder, Major

United States, Korea, Republic of, Spain, Argentina, United Kingdom, Sweden, Italy, Germany, France, Canada, Brazil
Istituto Auxologico Italiano

Recruiting

Potential Predictive Biological Markers of Major Depression Response to Citalopram Therapy in Anorexia Nervosa. (ANCITA)

Anorexia Nervosa

Italy
Cancer Institute and Hospital, Chinese Academy...

Recruiting

Postoperative Management for HNSCC Based on Pathological Response of Induction Chemotherapy and Immunotherapy (HN)

Head and Neck Cancer

China
Fondazione Policlinico Universitario Agostino Gemelli...

Recruiting

MAP THE SMA: a Machine-learning Based Algorithm to Predict THErapeutic Response in Spinal Muscular Atrophy (MAP_THE_SMA-01)

Spinal Muscular Atrophy

Italy
Fondazione Policlinico Universitario Agostino Gemelli...

Recruiting

SMN Circular RNAs as Potential Biomarkers for the Therapeutic Response to Nusinersen in Spinal Muscular Atrophy Patients

Spinal Muscular Atrophy

Italy
Aristotle University Of Thessaloniki
1st ORL Department, AHEPA Hospital, Aristotle University of Thessaloniki; Department... and other collaborators

Recruiting

Biomarkers of Response to Mepolizumab Treatment in Patients With Nasal Polyps With or Without Bronchial Asthma (CALIOPI)

Asthma | Chronic Rhinosinusitis With Nasal Polyps

Greece
University of Nottingham

Recruiting

Assessing the Dose-response of Muscle Protein Synthesis to "Super-whey" in Older Adults (ARLA-WHEY)

Sarcopenia

United Kingdom
Centre Leon Berard

Recruiting

Multiparametric Quantitative MRI and Response to Neoadjuvant Radiotherapy for Soft-tissue Sarcoma (SarQuantIRM)

Soft Tissue Sarcoma | Resectable Soft Tissue Sarcoma | Adult Soft Tissue Sarcoma

France
Assaf-Harofeh Medical Center

Recruiting

Medical vs Surgical Treatment in OSA Among Children

To Evaluate PSQ as Clinical Tool in the Decision Between Medical and Surgical Treatment for Adenotonsillar Hypertrophy | To Determine Clinical Response to Montelukast or Nasal Steroids Based on PSQ Results

Israel
University Hospital, Strasbourg, France

Recruiting

Feasibility of a Newborn Screening for Spinal Muscular Atrophy (SMA) in France: DEPISMA Prefigurator Project in Grand-Est and Nouvelle-Aquitaine (DEPISMA)

Feasibility of Neonatal Screening for Spinal Amyotrophy

France
Janbubi Jandaulyet

Recruiting

Does the Presence of Cervical Facet Tropism Affect the Response to Interlaminar Epidural Steroid Injections?

Cervical Disc Herniation | Cervical Radicular Pain | Facet Tropism

Turkey
AstraZeneca
SWOG Clinical Trials Partnerships; Daiichi Sankyo

Recruiting

A Study of Dato-DXd With or Without Durvalumab Versus Investigator's Choice of Therapy in Patients With Stage I-III Triple-negative Breast Cancer Without Pathological Complete Response Following Neoadjuvant Therapy (TROPION-Breast03)

Breast Cancer

United States, China, Denmark, United Kingdom, Korea, Republic of, Canada, Germany, Italy, Belgium, Spain, Japan, France, Taiwan, Greece, Brazil, Sweden, Puerto Rico

Search clinical trials for: major pathological response

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