Search clinical trials for: metabolite identification

Total 1795 results

Basilea Pharmaceutica

Completed

A Study to Assess the Mass Balance Recovery and Metabolite Profile & Identification of [14C]-APX001 in Healthy Males

Fungal Infection

United Kingdom
Kazia Therapeutics Limited
Quotient Sciences

Completed

Mass Balance Recovery, Metabolite Profile, and Metabolite Identification of [14C]-Paxalisib in Healthy Male Subjects

Healthy

United Kingdom
Reata, a wholly owned subsidiary of Biogen

Completed

A Human AME Study for Omaveloxolone

Healthy Male Subjects

United States
San Diego State University

Active, not recruiting

Dose-dependent Identification of Unique Biomarkers

Healthy

United States
AstraZeneca
Quotient Sciences

Completed

A Study to Assess the Mass Balance Recovery, Metabolite Profile and Metabolite Identification of [14C]AZD9833

ER-positive, HER2-negative Breast Cancer

United Kingdom
Senju Pharmaceutical Co., Ltd.
Quotient Sciences

Completed

Single Dose ADME Study of [14C]SJP-0008 in Healthy Male Subjects

Healthy Volunteers

United Kingdom
Bial R&D Investments, S.A.

Completed

Mass Balance Recovery and Metabolite Identification of Carbon-14 BIA 28-6156

Parkinson Disease

United Kingdom
AB Science

Completed

Mass Balance Recovery, Metabolite Profile and Metabolite Identification of 14C-AB1010 in Healthy Male Subjects

Healthy Volunteers

United Kingdom
Xenon Pharmaceuticals Inc.

Completed

Single-dose Mass Balance Recovery and Metabolite Profile and Identification of 14C-XEN1101

Healthy Volunteers

United Kingdom
Biogen
Denali Therapeutics Inc.

Completed

A Study of Mass Balance, Pharmacokinetics, Metabolite Profile, and Metabolite Identification of BIIB122/DNL151 in Healthy Male Subjects

Healthy Volunteers

United States
MedDay Pharmaceuticals SA
Quotient Sciences

Completed

Mass Balance Recovery, Metabolite Profile and Metabolite Identification of [14C]-MD1003 in Healthy Male Subjects

Healthy Volunteers

United Kingdom
AstraZeneca
Quotient Sciences

Completed

A Study to Assess the Mass Balance Recovery, Pharmacokinetics, Metabolite Profile and Metabolite Identification of [14C]AZD4831

Cardiovascular Disease

United Kingdom
AstraZeneca
Quotient Sciences

Completed

Mass Balance Recovery, Pharmacokinetics and Metabolite Profile and Identification of [14C]AZD7594

Asthma

United Kingdom
Celtaxsys, Inc.
Quotient Sciences

Completed

Mass Balance Recovery, Metabolite Profile and Metabolite Identification of [14C]-Acebilustat (CTX-4430)

Heathy Volunteers

United Kingdom
ASLAN Pharmaceuticals

Completed

Open, Single-dose/-Period Study to Assess Mass Balance Recovery, Metabolite Profile/Identification of 14C-Varlitinib

Healthy Volunteers

United Kingdom
Nabriva Therapeutics AG
Quotient Clinical

Completed

A Study to Assess Mass Balance Recovery, Metabolite Profile and Identification of IV and Oral 14C-BC-3781

Healthy

United Kingdom
Pfizer

Completed

Mass Balance Recovery, Metabolite Profile and Metabolite Identification of [14C]NXL104

Healthy

United Kingdom
Bial - Portela C S.A.

Completed

Mass Balance Recovery, Metabolite Profile and Metabolite Identification of [14C]-BIA 9-1067

Parkinson Disease

United Kingdom
Sanwa Kagaku Kenkyusho Co., Ltd.

Completed

A Study to Assess the Mass Balance Recovery, Metabolite Profile and Metabolite Identification of [14C]-SK-1405

Pruritus

United Kingdom
Henri Mondor University Hospital

Completed

Identification of a New Metabolite of Furosemide in Humans (PYPARK)

Treatment by Furosemide
Jiangsu HengRui Medicine Co., Ltd.

Unknown

the Food Effect Pharmacokinetic, Material Balance and Metabolite Identification of SP2086 in Healthy Volunteers

Type 2 Diabetes

China
Jiangsu HengRui Medicine Co., Ltd.

Completed

The Metabolite Identification and Material Balance Study of SP2086

Type 2 Diabetes
Seoul National University Hospital

Completed

Identification and Evaluation of Endogenous Markers for the Assessment of CYP3A Activity

Healthy

Korea, Republic of
LG Life Sciences

Completed

Study in Healthy Male Subjects Designed to Assess the Mass Balance Recovery, Metabolite Profile and Metabolite Identification of [14C] LC15-0444

Healthy

Korea, Republic of
Tioga Pharmaceuticals

Completed

A Metabolite Identification, Mass Balance, and PK Study of [14C]-Asimadoline to Healthy Adult Male Volunteers

Healthy

United States
Seoul National University Hospital
Ministry of Education Science and Technology, Korea

Completed

Identification and Evaluation of Endogenous Markers for the Assessment of CYP3A Activity Using Metabolomics

Healthy

Korea, Republic of
Hôpital NOVO

Not yet recruiting

Identification of Post-Traumatic Stress Disorder in Adult Patients With Substance Use Disorders (IRTIPAP)

Post Traumatic Stress Disorder

France
The First Affiliated Hospital with Nanjing Medical...

Not yet recruiting

Study on the Mechanism of ZhenQiFuZheng in the Treatment of Allergic Rhinitis Based on Intestinal Flora and Metabolites

Rhinitis, Allergic
Aalto University
Helsinki University Central Hospital; Business Finland

Recruiting

Early Identification of Age-related Hearing Impairment

Hearing Loss, Age-Related

Finland
Masonic Cancer Center, University of Minnesota
National Cancer Institute (NCI)

Recruiting

Evaluation of Early Identification of Cognitive Side Effects of Immunotherapy

Malignant Solid Neoplasm | Hematopoietic and Lymphatic System Neoplasm

United States
Centre Hospitalier Universitaire de Nīmes

Not yet recruiting

Identification of Limiting Factors in the Locomotor Activity of Individuals With Lower Limb Amputation: (AMPUTEEFACT)

Lower Limb Amputation
Ospedale San Raffaele
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico

Recruiting

Identification of New Biological Markers for the Progression of Mycobacterium Abscessus-induced Lung Disease in Cystic Fibrosis (BioMol-MA)

Non-Tuberculous Mycobacterial Pneumonia | Cystic Fibrosis Lung

Italy
VA Office of Research and Development

Not yet recruiting

A Partnered Evaluation to Improve the Identification and Management of Functional Impairment and Frailty Among Older Veterans in Primary Care Settings

Frailty | Functional Impairment

United States
University of Texas Southwestern Medical Center

Recruiting

Identification of Metabolic Phenotypes Associated With Melanoma Metastasis

Melanoma (Skin)

United States
Centre Hospitalier Universitaire de Besancon

Not yet recruiting

Identification of Biomarkers Associated With the Presence of Malignant Pancreatic Lesions Compared to Benign Lesions. (PANORAMA)

Benign Pancreatic Lesion

France
Fox Chase Cancer Center
Janssen Pharmaceuticals

Not yet recruiting

Increasing Pre-Surgical Identification of Muscle Invasive Tumor Evaluations Prior to Planned Cystectomy (INSITE) (INSITE)

Urothelial Carcinoma | Non-Muscle Invasive Bladder Urothelial Carcinoma | Muscle Invasive Bladder Urothelial Carcinoma

United States
Center for Reproductive Health & Gynecology
Butterfly Biosciences, Inc

Recruiting

UTERINE EVALUATION FOR THE IDENTIFICATION OF PATHOLOGY. This Study Will Compare the Intrauterine Pathology Detection Rate Between Standard of Care Hydrosonography, and a New Visual Saline Infusion Device Providing Direct Visualization of the Uterus.

Fertility Issues | Hysteroscopy | Gynecology | Hysteroscopy Technique | Uterus Abnormal | Infertility Female | Visualization

United States, Mexico
BrightHeart

Not yet recruiting

Fetal Heart Ultrasound Suspicious Radiographic Finding Identification - Reader Study

Congenital Heart Disease
University of Campania "Luigi Vanvitelli"
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico; University of Milan and other collaborators

Recruiting

The PRO-FUTURE Project (PRO-FUTURE)

Chronic Kidney Diseases | Ureteropelvic Junction Obstruction

Italy
Kessler Foundation

Not yet recruiting

A Strength-Based Intervention to Improve Job Interview Skills in Young Adults in a Community Setting

Autism Spectrum Disorder
Fundació Eurecat
University Rovira i Virgili

Not yet recruiting

Association Between Training Load and Lactate and Other Metabolites Analyzed by Metabolomic and Proteomic Techniques (PROTEOMET)

Lactate | Metabolomics | Proteomics | Sports Performance

Spain
Mayo Clinic

Recruiting

Non-Invasive Identification of Endometrial Cancer/Endometrial Atypical Hyperplasia With an AI-Based Classifier Applied to Transvaginal Ultrasound in Patients With Post-Menopausal Bleeding

Endometrial Carcinoma

United States
The Cleveland Clinic

Recruiting

Microbial Metabolites and Outcomes of Pregnancy Study (MMOPS)

Hypertensive Disorder of Pregnancy

United States
Poitiers University Hospital

Not yet recruiting

Anatomo-clinico-biological Profiles in Severe Nasal Polyps

NASAL POLYPS
Fundación Iniciativa para las Neurociencias (FINCE)

Not yet recruiting

Phenotyping and Identification of Biological Markers in STXBP1 Encephalopathy (FIMBEX)

STXBP1 Encephalopathy With Epilepsy

Spain
Center Eugene Marquis

Not yet recruiting

Identification of Risk Factors for Brain Recurrence in Patients With HER2-positive Localised Breast Cancer (CRANIUM)

HER2-positive Breast Cancer
Medical University of Vienna
University of Zurich; Centre Hospitalier Universitaire Dijon; Fundacion Clinic... and other collaborators

Not yet recruiting

Personalized Monitoring of Non-foveal, Non-vision Compromising Atrophic Age-related Macular Degeneration With Artificial Intelligence and Identification of Disease Progression (APENNINES)

Age-Related Macular Degeneration | Geographic Atrophy
Medical University of Vienna
University of Zurich; Centre Hospitalier Universitaire Dijon; Fundacion Clinic... and other collaborators

Not yet recruiting

Personalised Monitoring of Early and Intermediate Age-related Macular Degeneration With Artificial Intelligence and Identification of Disease Progression (SUDETES)

Age-Related Macular Degeneration
Fondazione IRCCS Ca' Granda, Ospedale Maggiore...

Recruiting

Identification of Biomarkers and Molecular Targets Involved on Intervertebral Disc Degeneration and Discogenic Pain

Intervertebral Disc Degeneration | Discogenic Pain | Discogenic Disease

Italy
Peking Union Medical College Hospital

Not yet recruiting

Biomarker Identification and Nutritional Intervention of Primary Sarcopenia Based on Gut-muscle Axis

Sarcopenia

China

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