Search clinical trials for: metformin

Total 2494 results

Eli Lilly and Company

Active, not recruiting

A Study to Evaluate Tirzepatide (LY3298176) in Pediatric and Adolescent Participants With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin or Basal Insulin or Both (SURPASS-PEDS)

Glucose Metabolism Disorders | Diabetes Mellitus, Type 2 | Diabetes Mellitus | Endocrine System Diseases | Type2 Diabetes | Metabolic Disease | T2DM (Type 2 Diabetes Mellitus) | T2D

United States, India, Australia, United Kingdom, Mexico, Brazil, Israel, France, Italy
Tufts Medical Center

Active, not recruiting

A Pragmatic Approach to Lower Diabetes Risk After Gestational Diabetes

Diabetes Mellitus, Type 2 | PreDiabetes | Diabetes, Gestational

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Active, not recruiting

Metformin Hydrochloride in Preventing Breast Cancer in Patients With Atypical Hyperplasia or In Situ Breast Cancer

Ductal Breast Carcinoma in Situ | BRCA1 Mutation Carrier | BRCA2 Mutation Carrier | Atypical Ductal Breast Hyperplasia | Lobular Breast Carcinoma in Situ

United States
Khyber Medical University Peshawar

Completed

Effect of Metformin and Combination of Olive Oil Plus Nutritional Supplements on Inflammatory Markers IL-6 and IL-8 in PCOS.

PCO

Pakistan
SINA Health Education and Welfare Trust
Horizon Pharmaceutical Pvt Ltd

Completed

Evaluating the Efficacy and Safety of Empagliflozin Addition to Insulin and Oral Antidiabetic Medication (OAD) Regimen in Poorly Controlled Type 2 Diabetes and Obese Patient

Glucose Metabolism Disorders | Diabetes Mellitus, Type 2 | Hypoglycemic Agents | Empagliflozin

Pakistan
SINA Health Education and Welfare Trust

Completed

Empagliflozin vs Metformin on Metabolic Dysfunction in Polycystic Ovary Syndrome With or Without Comorbidity or Multimorbidity

Polycystic Ovary Syndrome | Weight Gain | HbA1c

Pakistan
Daewoong Pharmaceutical Co. LTD.

Active, not recruiting

The Efficacy and Safety of DWP16001 in Combination With Metformin in T2DM Patients Inadequately Controlled on Metformin

Glucose Metabolism Disorders | Diabetes Mellitus, Type 2 | Diabetes Mellitus | Endocrine System Diseases | Metabolic Disease

China
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

An Endometrial Cancer Chemoprevention Study of Metformin

Gynecology

United States
Cerevel Therapeutics, LLC

Completed

A Trial to Evaluate the Effects of Itraconazole and Carbamazepine on the Pharmacokinetics of Emraclidine and of Emraclidine on the Pharmacokinetics of Metformin in Healthy Adult Participants

Healthy Volunteers

United States
Merck Sharp & Dohme LLC
Pfizer

Active, not recruiting

Ertugliflozin Type 2 Diabetes Mellitus (T2DM) Pediatric Study (MK-8835/PF-04971729) (MK-8835-059)

Type 2 Diabetes Mellitus

United States, Belgium, Canada, Colombia, Costa Rica, Dominican Republic, France, Guatemala, Hungary, Israel, Italy, Malaysia, Mauritius, Mexico, Philippines, Poland, Russian Federation, Saudi Arabia, Turkey, Ukraine, United Arab... and more
Mayo Clinic
National Institute on Aging (NIA)

Completed

Metformin Effect on Brain Function in Insulin Resistant Elderly People

Obesity | Insulin Resistance | Obesity, Abdominal

United States
PharmaLinea Ltd.

Completed

Daily Oral Iron Supplementation for Replenishment of Depleted Iron in Adults (IRON-RELOAD)

Iron-deficiency | Iron Deficiency Anemia

Slovenia
Genentech, Inc.

Active, not recruiting

To Evaluate the Safety, Tolerability, and Pharmacokinetics of Inavolisib Single Agent in Participants With Solid Tumors and in Combination With Endocrine and Targeted Therapies in Participants With Breast Cancer

Breast Cancer | Solid Tumor

United States, France, Spain, United Kingdom, Canada
Medical University of Vienna
Merck Serono GmbH, Germany

Active, not recruiting

Metformin Therapy in Non-diabetic AAA Patients (MetAAA)

Abdominal Aortic Aneurysm

Austria
Bristol-Myers Squibb

Completed

A Study Investigating Interactions Between BMS-986322 and Rosuvastatin, Metformin and Methotrexate in Healthy Participants

Healthy Participants

United States
University of Alberta
Canadian Institutes of Health Research (CIHR); Women and Children's Health... and other collaborators

Suspended

Dietary Fish Oil Intervention in Polycystic Ovary Syndrome (PCOS) (PCOS)

Polycystic Ovary Syndrome | Lipid Metabolism Disorders

Canada
Menoufia University

Completed

The Impact of Metformin on the Outcome of Gouty Arthritis in a Cohort of Egyptian Gouty Patients. (Mets in gout)

Gouty Arthritis

Egypt
Kaken Pharmaceutical

Active, not recruiting

A Study to Determine the Effect of KP-001 on Metformin and Midazolam Pharmacokinetics and the Effect of Clarithromycin on KP-001 Pharmacokinetics in Healthy Adult Participants

Healthy Adults

United States
Taipei Medical University Hospital
Taipei Medical University

Completed

Clinical Efficacy and Adverse Reactions of Antipsychotic Treatment

Schizophrenia | Metabolic Disturbance | Hyperprolactinemia

Taiwan
Medical University of Graz
Winclove Probiotics B.V.; Institut AllergoSan

Completed

Probiotic Intervention in PCOS (ProPCO-RCT)

Polycystic Ovary Syndrome

Austria
Canadian Urologic Oncology Group
British Columbia Cancer Agency; Prostate Cancer Canada; BC Cancer Foundation

Terminated

Metformin in Patients Initiating ADT as Prevention and Intervention of Metabolic Syndrome (PRIME)

Metabolic Syndrome | Prostate Cancer

Canada
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Gemcitabine Hydrochloride, Paclitaxel Albumin-Stabilized Nanoparticle Formulation, Metformin Hydrochloride, and a Standardized Dietary Supplement in Treating Patients With Pancreatic Cancer That Cannot be Removed by Surgery

Pancreatic Adenocarcinoma | Unresectable Pancreatic Carcinoma | Stage III Pancreatic Cancer AJCC v6 and v7 | Stage IV Pancreatic Cancer AJCC v6 and v7

United States
UNC Lineberger Comprehensive Cancer Center
Golfers Against Cancer Grant

Active, not recruiting

Metformin With the Levonorgestrel-Releasing Intrauterine Device for the Treatment of Complex Atypical Hyperplasia (CAH) and Endometrial Cancer (EC) in Non-surgical Patients

Endometrial Cancer | Complex Atypical Hyperplasia

United States
Zhujiang Hospital
Third Affiliated Hospital, Sun Yat-Sen University; Peking University Shenzhen... and other collaborators

Completed

Study of Efficacy, Weight Control, and Safety in Newly-diagnosed Type 2 Diabetes With Different Antidiabetic Therapy

Type 2 Diabetes Mellitus

China
Anuja Dokras
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Comparing the Effects of Oral Contraceptive Pills Versus Metformin (COMET-PCOS)

PCOS

United States
Sidney Kimmel Cancer Center at Thomas Jefferson...

Completed

Durvalumab With or Without Metformin in Treating Participants With Head and Neck Squamous Cell Carcinoma

Head and Neck Squamous Cell Carcinoma | Oropharyngeal Squamous Cell Carcinoma | Oral Cavity Squamous Cell Carcinoma

United States
Massimo Falconi

Active, not recruiting

Efficacy of Chemopreventive Agents on Disease-free and Overall Survival in Patients With Pancreatic Ductal Adenocarcinoma: The CAOS Study (CAOS)

Pancreatic Cancer | Overall Survival | Disease Free Survival

Italy
Kasr El Aini Hospital

Completed

Effect of Metformin on Non PCO Women Undergoing IVF/ICSI

Infertility

Egypt
Arkansas Children's Hospital Research Institute
National Institutes of Health (NIH); National Institute of General Medical... and other collaborators

Active, not recruiting

Bioenergetics and Metabolism in Pediatric Populations

Obesity | Type 2 Diabetes Mellitus | Insulin Resistance

United States
Joslin Diabetes Center

Enrolling by invitation

Oral Hypoglycemic Therapy for Monogenic Variant Carriers of the Joslin Medalist Study

Type 1 Diabetes | Monogenic Diabetes

United States
The Hospital for Sick Children
University of Alberta; University of Waterloo

Terminated

Metformin Treatment in Infants After Perinatal Brain Injury

Premature Birth | Hypoxic Ischemic Encephalopathy of Newborn

Canada
Jagiellonian University

Active, not recruiting

dataBase for Analysis of Rectal Cancer Oncological Results (BARO)

Rectal Cancer | Lymph Node Metastases | Metformin | Overall Survival | Disease-free Survival

Poland
University of Alabama at Birmingham
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Preventing Diabetes in the Deep South: Extending Partnerships and Adapting Interventions to Reach Rural Communities at High Risk.

Pre-diabetes

United States
José A. Luchsinger
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Albert... and other collaborators

Terminated

Brain Imaging in the Diabetes Prevention Program Outcomes Study (DPPOS-Brain)

Alzheimer Disease

United States
The University of Texas Health Science Center at...
National Institute on Aging (NIA)

Completed

Metformin for Preventing Frailty in High-risk Older Adults

Frailty

United States
Trisha Wise-Draper
American Cancer Society, Inc.

Active, not recruiting

Combining Pembrolizumab and Metformin in Metastatic Head and Neck Cancer Patients

Head and Neck Squamous Cell Carcinoma

United States
Novo Nordisk A/S

Withdrawn

Research Study to Compare Semaglutide Tablets With Empagliflozin or Metformin Tablets in People With Type 2 Diabetes

Diabetes Mellitus, Type 2

Thailand, Malaysia, Poland, India, Hungary, Mexico, Brazil, United States, Croatia, Romania, Bulgaria, Greece, Serbia
Garvan Institute of Medical Research
Weizmann Institute of Science

Active, not recruiting

Personalised Medicine in Pre-diabetes and Early Type 2 Diabetes (PREDICT)

Type 2 Diabetes Mellitus | Pre Diabetes

Australia
Boehringer Ingelheim

Completed

Diabetes Study of Linagliptin and Empagliflozin in Children and Adolescents (DINAMO)TM

Diabetes Mellitus, Type 2

United States, Canada, Thailand, Korea, Republic of, United Kingdom, China, Germany, Israel, Mexico, Argentina, Brazil, Colombia, Puerto Rico, Russian Federation
Khyber Medical University Peshawar

Completed

Independent and Additive Effects Of Micronutrients With Metformin In Patients With PCOS

PCOS

Pakistan
Sidney Kimmel Cancer Center at Thomas Jefferson...

Completed

Pilot Study of Metformin in Head and Neck Squamous Cell Cancer and Its Effects on Stromal-epithelial Metabolic Uncoupling

Head and Neck Squamous Cell Cancer

United States
Arkansas Children's Hospital Research Institute
National Institutes of Health (NIH); National Institute of General Medical... and other collaborators

Active, not recruiting

Immunometabolism in Pediatric Obesity (IPO)

Obesity | Type 2 Diabetes Mellitus | Insulin Resistance

United States
Ente Ospedaliero Ospedali Galliera

Active, not recruiting

A Randomized, 2x2 Factorial Design Biomarker Prevention Trial of Low-dose ASA and Metformin in Stage I-III Crc Patients (ASAMET)

Tertiary Prevention in Colon Cancer

Italy
University of Sao Paulo General Hospital

Completed

Effects of Myo-inositol in Women With Polycystic Ovary Syndrome

Polycystic Ovary Syndrome | Glucose Intolerance | Resistance, Insulin

Brazil
Taipei City Hospital
The One Biopharmaceutical Co., Ltd.

Completed

Clinical Trials Using HepatoKeeper Herbal Essentials to Treat Non-alcoholic Fatty Liver Disease and Metabolic Factors

Non-alcoholic Fatty Liver Disease | Liver Fibrosis | Liver Injury

Taiwan
HÜMEYRA ACIKAN

Completed

Effectiveness of Antidiabetic Treatment Applied in Childhood Obesity

Insulin Resistance | Childhood Obesity

Turkey
Assiut University

Terminated

Maternal and Fetal Outcome With Metformin Therapy for Obese Pregnant Women .

Metformin for Obese Pregnant Women

Egypt
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Temozolomide, Memantine Hydrochloride, Mefloquine, and Metformin Hydrochloride in Treating Patients With Glioblastoma Multiforme After Radiation Therapy

Glioblastoma | Gliosarcoma | Supratentorial Glioblastoma

United States
Mina Chung, MD
The Cleveland Clinic; American Heart Association

Active, not recruiting

Targeting Risk Interventions and Metformin for Atrial Fibrillation (TRIM-AF) (TRIM-AF)

Atrial Fibrillation

United States
Coordinación de Investigación en Salud, Mexico

Suspended

Omega 3 Polyunsaturated Fatty Acids (PUFA) or Magnesium in Obese Polycystic Ovary Syndrome Patients (OMgObPCOS)

Obesity | Polycystic Ovary Syndrome

Mexico

Search clinical trials for: metformin

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