Search clinical trials for: multicenter randomized control clinical trial

Total 117826 results

Beijing Tiantan Hospital

Not yet recruiting

Ticagrelor With Aspirin Dual Antiplatelet Therapy Combined With Intravenous Thrombolysis for Ischemic Stroke (TAPIS)

Ischemic Stroke, Acute
Huashan Hospital

Recruiting

aSAH Treatment Based on Intraventricular ICP Monitoring: A Prospective, Multicenter, Randomized and Controlled Trial (ASTIM-MT)

Intracranial Pressure Increase | Aneurysmal Subarachnoid Hemorrhage

China
Peking University Third Hospital
Beijing Yanqing Hospital

Recruiting

A Prospective Multicenter Cohort Study About Internal Fixation Using PFUN Versus PFNA for Femoral Intertrochanteric Fracture

Femoral Intertrochanteric Fractures

China
Auckland City Hospital

Not yet recruiting

Depth of Anesthesia on Postoperative Delirium and Cognitive After Surgery (Balanced-2)

Delirium | Anesthesia | Cognitive Decline | Cognition Disorder | Surgery-Complications | Delirium, Postoperative
University Hospital, Tours
Hospices Civils de Lyon; Centre Hospitalier Universitaire Dijon; CHU de Reims; University... and other collaborators

Not yet recruiting

Effect of Long-term Carvedilol to Prevent Decompensation or Death in Patients With Asymptomatic Child-Pugh A5 to B8 Cirrhosis and Clinically Significant Portal Hypertension: a Multicenter Double-blind Randomized Control Trial (CARVECIR)

Clinically Significant Portal Hypertension | Asymptomatic Cirrhosis

France
Escient Pharmaceuticals, Inc

Recruiting

Phase 2, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Effects of EP262 in Subjects With Chronic Spontaneous Urticaria (CALM-CSU)

Chronic Spontaneous Urticaria

Spain, United States, Germany, Canada, Poland, Netherlands
University of California, San Diego
National Institute on Drug Abuse (NIDA); RTI International; Drexel University

Recruiting

A Systems Analysis and Improvement Approach for Optimizing HIV Service Delivery in Syringe Services Programs (SAIA-SSP-HIV)

HIV Infections

United States
National Cancer Institute, Lithuania

Recruiting

Transanal Irrigation - Best Treatment Possibility for Low Anterior Resection Syndrome? Multicenter, Randomized Clinical Trial

Low Anterior Resection Syndrome

Lithuania
University Medical Center Groningen

Not yet recruiting

Clinical Validation of the C-Arm Rotational View (CARV) to Avoid Rotational Malalignment After Intramedullary Nailing of Tibial Shaft Fractures.

Surgery | Tibial Fractures | Complication,Postoperative

Australia, Netherlands
First Affiliated Hospital of Zhejiang University
Zhejiang Cancer Hospital; West China Hospital; Third Affiliated Hospital, Sun... and other collaborators

Recruiting

A Multicenter, Randomized, Parallel-controlled Clinical Trial Protocol to Validate the Safety and Efficacy of a Steep Pulse Therapy System for the Treatment of Liver Tumors

A Steep Pulse Therapy System for the Treatment of Liver Tumors

China
wang shusen

Recruiting

Tucidinostat and Metronomic Capecitabine for Metastatic Triple-negative Breast Cancer:a Multicenter,Open-label, Randomized Controlled, Phase II Clinical Trial

Triple Negative Breast Cancer

China
Assistance Publique Hopitaux De Marseille

Recruiting

Evaluation of the Efficacy of Early Implantation of a Percutaneous Left Ventricular Assist Devices in Acute Coronary Syndrome Complicated by Cardiogenic Shock Compared to Conventional Therapy: a Prospective, Multicenter, Randomized, Controlled and Open-label Clinical Trial (ULYSS)

Cardiogenic Shock

France
Wex Pharmaceuticals Inc.

Recruiting

A Randomized, Double-Blind, Placebo Controlled, Multicenter, Efficacy and Safety Trial of Single Cycle Tetrodotoxin in the Treatment of Chemotherapy Induced Neuropathic Pain

Chemotherapy-induced Peripheral Neuropathy | Chemotherapy-induced Neuropathic Pain

United States
Chengdu Easton Biopharmaceuticals Co,Ltd

Recruiting

A Randomized, Double-blind, Placebo-controlled, Multicenter Clinical Trial to Evaluate the Clinical Efficacy and Safety of Yogliptin Tablets

Type 2 Diabetes

China
The Affiliated Nanjing Drum Tower Hospital of Nanjing...
Nanjing First Hospital, Nanjing Medical University; Wuxi People's Hospital; Changzhou... and other collaborators

Recruiting

Effects of Liraglutide, Empagliflozin and Linagliptin on the Cognitive Function in T2DM Patients With Mild Cognitive Impairment: a Multicenter, Randomized, Parallel Controlled Clinical Trial (LIGHT-MCI)

Type 2 Diabetes Mellitus | Mild Cognitive Impairment

China
Universität des Saarlandes
Interdisciplinary Center Clinical Trials (IZKS), University Medical Center...

Recruiting

A Prospective, Multicenter, Randomized, Blinded, Sham-controlled, Feasibility Study of Renal Denervation in Patients With Chronic Heart Failure (RE-ADAPT-HF)

Chronic Heart Failure | Cardio-Renal Syndrome

Germany
Peking University Third Hospital
West China Hospital; Shanghai Ninth People's Hospital Affiliated to Shanghai... and other collaborators

Recruiting

A Prospective Multicenter Cohort Study About Internal Fixation Using FNS Versus MCS for Femoral Neck Fracture

Femoral Neck Fractures

China
University Hospital Tuebingen
Federal Ministry of Health, Germany; University of Ulm; Department of Psychiatry... and other collaborators

Recruiting

Treatment of Major Depressive Disorder With Bilateral Theta Burst Stimulation (TBS-D)

Major Depressive Disorder

Germany
The Affiliated Hospital of Inner Mongolia Medical...
Inner Mongolia Agricultural University; Inner Mongolia People's Hospital; Inner... and other collaborators

Recruiting

Probiotics for Gout / Hyperuricemia: A Randomized, Intervention, Parallel Controlled, Multicenter Clinical Trial

Hyperuricemia | Gout

China
Sanofi
Regeneron Pharmaceuticals

Completed

A Phase 4, Randomized, Double-blind, Placebo-controlled,Multicenter, Parallel-group Study of the Effect of Dupilumab on Sleep Disturbance in Patients With Uncontrolled Persistent Asthma (MORPHEO)

Asthma

Spain, United States, Argentina, Canada, Germany, Italy, Netherlands, Portugal, Russian Federation, Ukraine, United Kingdom
Shanghai Eye Disease Prevention and Treatment Center
Xinhua Hospital, Shanghai Jiao Tong University School of Medicine; Shanghai... and other collaborators

Completed

The Effectiveness and Safety of Low-intensity Single-wavelength Red Light in Controlling High Myopia in Children and Adolescents：A Randomized, Controlled, Multicenter Clinical Trial

Age 3 to 16 Years (Inclusive), Male or Female | Clinical Diagnosis Confirming That Myopia Has Occurred in at Least One Eye | The Guardian Voluntarily Signed the Subject's Informed Consent Form

China
Medesis Pharma SA

Terminated

NanoMn®_COVID-19 A Prospective, Multicenter, Randomized, Placebo-controlled, Parallel-group, Double-blind Trial to Evaluate the Clinical Efficacy of NanoManganese® on Top of Standard of Care, in Adult Patients With Moderate to Severe Coronavirus Disease 2019 (COVID-19)

COVID-19 Pandemic

Brazil
AbbVie

Completed

A Multicenter, Randomized, Double-Blind, Placebo Controlled Induction Study to Evaluate the Efficacy and Safety of Risankizumab in Participants With Moderately to Severely Active Ulcerative Colitis

Ulcerative Colitis (UC)

United States, Argentina, Austria, Belgium, Brazil, Bulgaria, Canada, Chile, China, Colombia, Croatia, Czechia, Denmark, Egypt, France, Germany, Greece, Israel, Italy, Japan, Korea, Republic of, Latvia, Lithuania, Malaysia, Mexico, Nether... and more
Beijing Tiantan Hospital
Ministry of Science and Technology of the People's Republic of China

Active, not recruiting

Intensive Medical Therapy for High-risk Intracranial or Extracranial Atherosclerosis (INSPIRES)

Transient Ischemic Attack | Acute Stroke

China
3M

Completed

Randomized, Controlled Multicenter Trial of Vacuum Assisted Closure Therapy™ in Diabetic Foot Ulcers

Diabetic Foot Ulcers

United States, Canada
Holy Stone Healthcare Co., Ltd
inVentiv Health Clinical

Completed

A Phase 2a, Multicenter, Randomized, Double-blind, Parallel Group, Placebo-controlled Trial of IBD98-M

Colitis, Ulcerative

Italy
Gachon University Gil Oriental Medical Hospital
Kyung Hee University Hospital at Gangdong; Kyunghee University Medical Center; Sangji University Oriental Medical Hospital and other collaborators

Completed

Efficacy and Safety of Ucha-Shinki-Hwan on Korean Patients With Cold Hypersensitivity in the Hands and Feet-Double Blinded, Randomized, Multicenter, Placebo Controlled Clinical Trial

Cold Hypersensitivity

Korea, Republic of
Universidade Federal do Rio de Janeiro
Financiadora de Estudos e Projetos; Hospital Universitario Pedro Ernesto; National... and other collaborators

Completed

Nitazoxanide Therapy for Patients With COVID-19 Pneumonia

Pneumonia, Viral | Covid19 | Corona Virus Infection

Brazil
Pfizer

Completed

Randomized, Double-Blind, Placebo-Controlled, Phase 2 Study In Subjects With Osteoarthritic Pain Of The Knee

Osteoarthritis, Knee

Korea, Republic of, United States
Daiichi Sankyo, Inc.

Completed

A Multicenter, Randomized, Placebo-Controlled, Double-Blind Study of SUN13834 in Adult Subjects With Atopic Dermatitis

Atopic Dermatitis

United States
Gachon University Gil Oriental Medical Hospital
DongGuk University; Sangji University Oriental Medical Hospital, Korea

Completed

A Pilot Study Exploring the Efficacy and Safety of Herbal Medicine on Korean Obese Women With Metabolic Syndrome Risk Factors - Double Blinded, Randomized, Multicenter, Placebo Controlled Clinical Trial -

Obesity | Metabolic Syndrome

Korea, Republic of
AO Clinical Investigation and Publishing Documentation

Completed

PHILOS Augmented - a Multicenter Randomized Controlled Trial

Humerus Fractures | Closed Fracture of the Proximal Humerus

Belgium, Austria, Germany, Switzerland
Zhujiang Hospital
The First Affiliated Hospital of Anhui Medical University; The First Affiliated... and other collaborators

Unknown

Transurethral Plasmakinetic Enucleation of Prostate Versus Transurethral Resection of Prostate (ERP)

Benign Prostatic Hyperplasia

China
The George Institute
National Health and Medical Research Council, Australia; Baxter Healthcare...

Completed

A Clinical Trial of IntensiVE Dialysis (ACTIVE)

End Stage Renal Disease | Renal Replacement Therapy | End Stage Kidney Disease | Renal Dialysis | Uremia

New Zealand, Canada, Australia, China
Second Affiliated Hospital, School of Medicine,...

Unknown

Non-inferiority Evaluation of Multicenter, Randomized, Single-blind, Parallel-controlled Clinical Trials on the Safety and Efficacy of Full-suture Anchors for Rotator Cuff Injury and/or Shoulder Instability Surgery (MST-002)

Shoulder Instability Rotator Cuff Injury

China
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Unknown

A Randomized, Double-blind, Placebo-controlled, Multicenter and Phase Ⅱa Clinical Trial for the Effectiveness and Safety of Baicalein Tablets in the Treatment of Improve Other Aspects of Healthy Adult With Influenza Fever

Influenza
Pfizer

Terminated

A Phase 2B Multicenter, Randomized, Comparative Trial Of UK-453,061 Versus Etravirine In Combination With Darunavir/Ritonavir And A Nucleos(t)Ide Reverse Transcriptase Inhibitor For The Treatment Of Antiretroviral Experienced HIV-1 Infected Subjects With Evidence Of NNRTI Resistant HIV-1

HIV-1

Spain, United Kingdom, Malaysia, United States, Portugal, Brazil, Germany, Italy, Poland, Puerto Rico, South Africa, Taiwan, Ukraine
Pfizer

Completed

Subcutaneous Treatment In Randomized Subjects To Evaluate Safety And Efficacy In Generalized Lupus Erythematosus (BUTTERFLY)

Lupus Erythematosus, Systemic

United States, Germany, Taiwan, Hungary, Poland, Colombia, Argentina, Romania, Chile, Puerto Rico, Korea, Republic of, Moldova, Republic of, Peru
Universitätsklinikum Köln
The Clinical Trials Centre Cologne

Unknown

A Multicenter, Randomized, Controlled Study to Assess Mitral vAlve reconsTrucTion for advancEd Insufficiency of Functional or iscHemic ORigiN (MATTERHORN)

Mitral Valve Insufficiency

Germany
Daewon Pharmaceutical Co., Ltd.

Completed

A Multicenter, Randomized, Open-labeled, Cross-over, Active-controlled, Phase IV Clinical Trial to Evaluate the Preference of Formulation and the Efficacy and Safety of Renamezin and Kremezin in Pre-dialysis Patients With Chronic Renal Failure

Chronic Renal Failure

Korea, Republic of
Teva Pharmaceuticals USA

Completed

A Randomized, Double-Blind, Parallel-Group, Vehicle-Controlled, Multicenter Study Comparing Diclofenac Sodium Gel, 3% to Solaraze® Gel, 3% in the Treatment of Actinic Keratosis on the Face or Bald Scalp

Actinic Keratosis

United States
Opexa Therapeutics, Inc.

Completed

Study of Tcelna (Imilecleucel-T) in Secondary Progressive Multiple Sclerosis (Abili-T)

Multiple Sclerosis | Autoimmune Diseases of the Nervous System | Disease Progression | Secondary Progressive Multiple Sclerosis | Brain Atrophy

United States, Canada
DePuy Spine

Completed

A Multicenter, Randomized, Double-blind, Placebo Controlled, Clinical Trial to Evaluate the Safety, Tolerability and Preliminary Effectiveness of 2 Doses of Intradiscal rhGDF-5 (Single Administration) for the Treatment of Early Stage Lumbar Disc Degeneration

Degenerative Disc Disease

United States
Actelion

Completed

Effects of the Combination of Bosentan and Sildenafil Versus Sildenafil Monotherapy on Pulmonary Arterial Hypertension (PAH) (Compass-2)

Pulmonary Arterial Hypertension

United States, Denmark, Sweden, Germany, Spain, Brazil, Saudi Arabia, Portugal, Greece, Slovakia, United Kingdom, Czech Republic
AcelRx Pharmaceuticals, Inc.

Completed

A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial to Evaluate the Efficacy and Safety of the Sufentanil NanoTab PCA System/15 mcg (Zalviso™) for the Treatment of Post-Operative Pain in Patients After Open Abdominal Surgery

Post-Operative Pain

United States
AcelRx Pharmaceuticals, Inc.

Completed

A Multicenter, Randomized, Open-Label, Parallel-Group Trial to Compare the Efficacy and Safety of the Sufentanil NanoTab PCA System/15 mcg (Zalviso™)to Intravenous Patient-Controlled Analgesia With Morphine for the Treatment of Acute Post-Operative Pain

Post-Operative Pain

United States
SK Life Science, Inc.

Completed

A Phase 2, Multicenter, Randomized, Double-blind, Placebo Controlled Study for the Pain of Diabetic Peripheral Neuropathy

Painful Diabetic Neuropathy

United States
Hospital Universitari Vall d'Hebron Research Institute
Hospital Clinic of Barcelona; Hospital Universitari de Bellvitge; Hospital Vall... and other collaborators

Completed

Multicenter, Randomized Placebo-controlled Clinical Trial to Evaluate the Effect of Perioperative Use of Tranexamic Acid on Transfusion Requirements and Surgical Bleeding in Major Spine Surgery

Hemorrhage | Blood Transfusion | Spinal Fusion | Antifibrinolytic Agents

Spain
BioCryst Pharmaceuticals

Completed

A Phase II, Multicenter, Randomized, Placebo -Controlled, Study To Evaluate The Efficacy and Safety Of Intramuscular Peramivir 600 mg In Subjects With Uncomplicated Acute Influenza

Acute, Uncomplicated Human Influenza

United States, Australia, New Zealand, South Africa
SK Life Science, Inc.

Completed

A Multicenter, Double-Blind, Randomized, Placebo-Controlled, 12-Week, Dose-Range-Finding Trial of YKP10811 Capsules Administered Once Daily to Subjects With Chronic Idiopathic Constipation

Chronic Idiopathic Constipation

United States

3

Subscribe