Search clinical trials for: neoantigen

Total 137 results

First Affiliated Hospital of Wenzhou Medical University

Not yet recruiting

Neoantigen Reactive T Cells c for Chinese Patients With Advanced Gastric Cancer

Advanced Gastric Cancer
JIANG LONGWEI
Nanjing University

Recruiting

A Study of Tumor Neoantigen-specific T Cells in the Treatment of Advanced Solid Tumors (Neoantigen-T)

Tumor, Solid

China
Yongyi Zeng

Not yet recruiting

Neoantigen Vaccine Plus Capecitabine as Adjuvant Therapy for Intrahepatic Cholangiocarcinoma After Radical Resection

Intrahepatic Cholangiocarcinoma
Wu Wenming
NeoCura

Not yet recruiting

XH001 Combination With Ipilimumab and Chemotherapy for Patients With Resected Pancreatic Cancer

Pancreatic Cancer

China
Sichuan University

Recruiting

Neoantigen Vaccine Plus Anti-PD1 and Chemotherapy as an Adjuvant Therapy for Pancreatic Cancer

Pancreatic Cancer | Adjuvant Therapy

China
Jonsson Comprehensive Cancer Center

Not yet recruiting

A Vaccine (Neoantigen-Targeted ppDC) for the Treatment of H3 G34-mutant Diffuse Hemispheric Glioma

Diffuse Hemispheric Glioma, H3 G34-Mutant

United States
Second Affiliated Hospital of Wenzhou Medical University

Recruiting

Application of MRD Combined With Personalized Vaccine in the Treatment of Postoperative Recurrence Prevention of EOC

Epithelial Ovarian Cancer

China
Jinling Hospital, China
Jiangsu Synthgene Biotechnology Co.Ltd.

Recruiting

Study of Neoantigen mRNA Vaccines in Patients With Resectable Pancreatic Cancer

Pancreatic Cancer

China
The University of Hong Kong-Shenzhen Hospital

Not yet recruiting

iTAPVR Study - Phase II Randomized Study

Advanced Tumors
Second Affiliated Hospital of Guangzhou Medical...

Recruiting

Anti-cancer Neoantigen mRNA Vaccine to Treat Solid Tumors

Solid Tumor, Adult

China
Second Affiliated Hospital of Guangzhou Medical...

Recruiting

Anti-cancer Neoantigen Polypeptide Vaccine to Treat Solid Tumors

Solid Tumor, Adult

China
Shanghai Jiao Tong University School of Medicine

Recruiting

Treatment of Advanced Endocrine Tumor With Iindividualized mRNA Neoantigen Vaccine (mRNA-0523-L001)

Medullary Thyroid Cancer | Pancreatic Neuroendocrine Tumor | Adrenal Cortical Carcinoma | Thymic Neuroendocrine Carcinoma

China
The Affiliated Nanjing Drum Tower Hospital of Nanjing...

Recruiting

Efficacy and Safety of Neoantigen Peptide Vaccine in the Treatment of Advanced NSCLC Progressed After EGFR-TKI Treatment

NSCLC | EGFR Gene Mutation

China
Sir Run Run Shaw Hospital
Hangzhou Neoantigen Therapeutics Co., Ltd.

Recruiting

Clinical Study of Personalized mRNA Vaccine Encoding Neoantigen in Combination With Standard First-line Treatment in Subjects With Advanced Digestive System Neoplasms

Digestive System Neoplasms

China
Sir Run Run Shaw Hospital
Hangzhou Neoantigen Therapeutics Co., Ltd.

Recruiting

Clinical Study of Personalized mRNA Vaccine Encoding Neoantigen in Subjects With Resected Digestive System Neoplasms

Digestive System Neoplasms

China
Sir Run Run Shaw Hospital
Hangzhou Neoantigen Therapeutics Co., Ltd.

Recruiting

Clinical Study of Personalized mRNA Vaccine Encoding Neoantigen Alone in Subjects With Advanced Digestive System Neoplasms

Digestive System Neoplasms

China
Peking Union Medical College Hospital

Recruiting

A Clinical Study of mRNA Vaccine (ABOR2014/IPM511) in Patients With Advanced Hepatocellular Carcinoma

Advanced Hepatocellular Carcinoma

China
Stemirna Therapeutics
Peking University Cancer Hospital & Institute

Not yet recruiting

Clinical Study of mRNA Vaccine in Patients With Advanced Malignant Solid Tumors

Advanced Malignant Solid Tumors
jianming xu
NeoCura

Recruiting

A Safety and Efficacy Study of XH001 Combined With Sintilimab Injection in Advanced Solid Tumors

Solid Tumor

China
Merck Sharp & Dohme LLC
ModernaTX, Inc.

Recruiting

A Clinical Study of V940 Plus Pembrolizumab in People With High-Risk Melanoma (V940-001)

Melanoma

Spain, Italy, Poland, Brazil, Australia, Chile, Canada, Portugal, Turkey, Germany, Greece, Israel, Sweden, New Zealand, United States, Belgium, France, Taiwan, United Kingdom, South Africa, Denmark, Argentina, Colombia, Japan, Switzerland
Ruijin Hospital
Shanghai Xinpu BioTechnology Company Limited

Recruiting

Personalized Tumor Vaccines and Pembrolizumab in Patients With Advanced Solid Tumors

Advanced Solid Tumor

China
Ruijin Hospital

Recruiting

Personalized Tumor Vaccines and Pabolizumab in Patients With Advanced Pancreatic Cancer

Advanced Pancreatic Cancer

China
Neogap Therapeutics AB
Karolinska University Hospital; CTC Clinical Trial Consultants AB; Region Västmanland and other collaborators

Recruiting

A First-In-Human Trial of pTTL in Advanced Colorectal Cancer

Colorectal Cancer

Sweden
Cancer Institute and Hospital, Chinese Academy...

Recruiting

LK101 Combined With PD-1 or PD-L1 Monoclonal Antibody in the Treatment of Lung Cancer

Advanced Lung Carcinoma

China
BGI, China
Fudan University; Shanghai 10th People's Hospital

Recruiting

Neo-T in Treating Patients With Advanced Solid Tumors(GI-NeoT-03)

Solid Tumor

China
BGI, China
Wuhan Union Hospital, China

Recruiting

Treatment of Advanced Solid Tumors With Neo-T(GI-NeoT-02)

Solid Tumor

China
National Health Research Institutes, Taiwan
National Cheng-Kung University Hospital

Recruiting

Neoantigen Derived DCs as Cancer Treatment

Solid Tumor | Refractory Tumor

Taiwan
Shanghai Zhongshan Hospital

Not yet recruiting

Clinical Study of mRNA Vaccine in Patients With Liver Cancer After Operation

Posto Perative Hepatocellular Carcinoma
The First Affiliated Hospital of Nanchang University
Shanghai Dengding BioAI Co.

Recruiting

Using Neoantigen Peptide Vaccine/Neoantigen-based DC to Treat Advanced Malignant Solid Tumors

Advanced Malignant Solid Tumors

China
Washington University School of Medicine
Incyte Corporation; PapiVax Biotech, Inc.

Recruiting

Neoantigen-based Personalized DNA Vaccine With Retifanlimab PD-1 Blockade Therapy in Patients With Newly Diagnosed, Unmethylated Glioblastoma

Unmethylated Glioblastoma

United States
TVAX Biomedical
FDA Office of Orphan Products Development

Recruiting

Study of Neoantigen-specific Adoptive T Cell Therapy for Newly Diagnosed MGMT Negative Glioblastoma Multiforme (GBM)

Glioblastoma Multiforme of Brain

United States
SLK Kliniken Heilbronn GmbH

Recruiting

IVAC-RCC-001: A Personalized Neoantigen Vaccine as Add-on to Standard of Care Checkpoint Inhibitor in Advanced/Metastatic RCC Patients

Advanced Renal Cell Carcinoma

Germany
Fudan University

Recruiting

Peripheral Blood Neoantigen Specific T Cells Predict the Efficacy of Immunotherapy for Esophageal Squamous Cell Carcinoma

Esophageal Squamous Cell Carcinoma

China
Shanghai 10th People's Hospital
Hangzhou NeoVax Biotechnology Co. LTD

Recruiting

Neoantigens Phase I Trial in Newly Diagnosed Glioblastoma Patients

Glioma, Malignant | Antigen-specific Vaccines | Individualized Treatment

China
University Medical Center Ho Chi Minh City (UMC)

Not yet recruiting

Computational Prediction and Experimental Validation of Gastric Cancer Associated Neoantigens

Gastric Cancer | Neoantigens

Vietnam
University Medical Center Ho Chi Minh City (UMC)

Not yet recruiting

Computational Prediction and Experimental Validation of Esophageal Cancer Associated Neoantigens

Esophageal Cancer | Neoantigen

Vietnam
Instituto de Medicina Regenerativa

Recruiting

Pilot Study of Neoantigen Peptides and Leukine for the Treatment of Neoplasms

Neoplasms

Mexico
YueJuan Cheng
NeoCura

Recruiting

Safety and Efficacy of Personalized Neoantigen Vaccine in Advanced Solid Tumors

Solid Tumor

China
Sichuan University

Not yet recruiting

A Translational Study of Tumor Antigen-pulsed DC Vaccine for ESCC

Esophageal Squamous Cell Carcinoma

China
Second Affiliated Hospital, School of Medicine,...
Hangzhou Neoantigen Therapeutics Co., Ltd.

Recruiting

Neoantigen Vaccine in Esophagus Cancer Patients Following Neoadjuvant Therapy and Surgical Resection

Resectable Esophageal Cancer

China
Mayo Clinic

Recruiting

Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors (PNeoVCA)

Metastatic Renal Cell Carcinoma | Anatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IIIA Breast Cancer AJCC v8 | Anatomic Stage IIIB Breast Cancer AJCC v8 | Anatomic Stage IIIC Breast Cancer AJCC v8 | Prognostic Stage III Breast Cancer AJCC v8 | Prognostic Stage IIIA Breast Cancer AJCC v8 and other conditions

United States
West China Second University Hospital

Not yet recruiting

Dendritic Cell Vaccination With Standard Postoperative Chemotherapy for the Treatment of Adult Ovarian Cancer

Recurrent Ovarian Cancer

China
Sichuan University

Not yet recruiting

Personalized Immune Cell Therapy Targeting Neoantigen of Malignant Solid Tumors

Melanoma | Carcinoma | Colorectal Cancer | Bladder Cancer

China
Shen Lin
NeoCura

Not yet recruiting

Safety and Efficacy of Personalized Neoantigen Vaccine in Advanced Gastric Cancer

Gastric Cancer

China
Stemirna Therapeutics

Recruiting

A Study of Neoantigen mRNA Personalised Cancer in Patients With Advanced Solid Tumors

Solid Tumor

Australia, Austria
jianming xu
NeoCura

Recruiting

Safety and Efficacy of Personalized Neoantigen Vaccine in Advanced Gastric Cancer, Esophageal Cancer and Liver Cancer

Gastric Cancer | Esophageal Cancer | Liver Cancer

China
Vall d'Hebron Institute of Oncology
Banc de Sang i Teixits

Recruiting

Assessment of the Safety and Tolerability of ex Vivo Next-generation Neoantigen-selected Tumor-infiltrating Lymphocyte (TIL) Therapy in Advanced Epithelial Tumors and Immune Checkpoint Blockade (ICB) Resistant Solid Tumors (NEXTGENTIL-ACT)

Epithelial Tumors, Malignant | Malignant Solid Tumor

Spain
Washington University School of Medicine
National Cancer Institute (NCI); Leidos; UNICO Foundation

Recruiting

Neoantigen Vaccines in Pancreatic Cancer in the Window Prior to Surgery

Pancreatic Cancer | Pancreas Cancer | Cancer of the Pancreas

United States
Fred Hutchinson Cancer Center
Amazon.com Services LLC

Recruiting

Personalized Neo-Antigen Peptide Vaccine for the Treatment of Stage IIIC-IV Melanoma or Hormone Receptor Positive Her2 Negative Metastatic Refractory Breast Cancer

Anatomic Stage IV Breast Cancer AJCC v8 | Prognostic Stage IV Breast Cancer AJCC v8 | Metastatic Cutaneous Melanoma | Unresectable Cutaneous Melanoma | Clinical Stage III Cutaneous Melanoma AJCC v8 | Pathologic Stage IIIC Cutaneous Melanoma AJCC v8 | Pathologic Stage IIID Cutaneous Melanoma AJCC... and other conditions

United States
National Cancer Institute (NCI)

Recruiting

Cancer Preventive Vaccine Nous-209 for Lynch Syndrome Patients

Lynch Syndrome

United States, Puerto Rico

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