Search clinical trials for: nucleoside analogues

Total 453 results

Qilu Hospital of Shandong University

Recruiting

Development and Validation of Models to Predict Functional Cure in Patients With CHB After Peg-IFN Based Therapy

Hepatitis B, Chronic

China
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Recruiting

A Clinical Study of TQA3605 Tablets Monotherapy or in Combination With Nucleoside (Acid) Analogues in Treatment Naive and Treated Patients With Chronic Hepatitis B

Chronic Hepatitis b

China
Wen-hong Zhang
The First Affiliated Hospital with Nanjing Medical University; The First Affiliated... and other collaborators

Not yet recruiting

Predictive Value of HBV pgRNA on Long-term Outcomes in Hepatitis B Patients Treated With Antiviral Therapy

HCC | HBV

China
Beijing Ditan Hospital

Recruiting

Study of COVID-19 Infection and Its Clinical Prognosis in Chronic Hepatitis B Patients With Antiviral Therapy

Chronic Hepatitis B | COVID-19 Infection

China
National Taiwan University Hospital
PharmaEssentia

Recruiting

Comparing P1101 to Entecavir in Patients With HBeAg(-) Hepatitis B Under Long-term Nucleos(t)Ide Analogue Therapy

Chronic Hepatitis B Virus Infection

Taiwan
Beijing Ditan Hospital
Beijing YouAn Hospital; Beijing 302 Hospital/5th Medical Center of Chinese...

Recruiting

The Study on Optimal Treatment and Clinical Outcome of Chronic Hepatitis B Patients With Inactive Hypoviremia

Chronic Hepatitis B

China
Beijing Ditan Hospital
Beijing YouAn Hospital; Beijing 302 Hospital/5th Medical Center of Chinese...

Recruiting

The Study on Clinical Outcome and Treatment Optimization of Chronic Hepatitis B Patients With Hypoviremia

Chronic Hepatitis B

China
Third Affiliated Hospital, Sun Yat-Sen University

Recruiting

Peginterferon Treatment Study for Inactive Chronic Hepatitis B Patients

Hepatitis B, Chronic

China
Shanghai Pudong Hospital

Not yet recruiting

Plasma Purification and Chronic Hepatitis B

Chronic Hepatitis b
Third Affiliated Hospital, Sun Yat-Sen University

Recruiting

Nucleoside (Acid) Analogues Treatment in Patients With Normal ALT and Positive HBVDNA. (ALTHBV)

Hepatitis B Virus

China
Third Affiliated Hospital, Sun Yat-Sen University

Recruiting

Three Types of Nucleotide/Nucleoside Analogues Therapy in Patients With Hepatitis b Virus Related Compensated Cirrhosis

Hepatitis B | Compensated Cirrhosis

China
Third Affiliated Hospital, Sun Yat-Sen University

Recruiting

Three Types of Nucleotide/Nucleoside Analogues Therapy in Patients With Chronic Hepatitis b

Chronic Hepatitis b

China
Third Affiliated Hospital, Sun Yat-Sen University

Recruiting

Three Types of Nucleotide/Nucleoside Analogues Treatment in HBV Related ACLF (HBV)

Acute-On-Chronic Liver Failure | Hepatitis B

China
Chengdu Suncadia Medicine Co., Ltd.

Active, not recruiting

A Phase II Clinical Study of the Efficacy and Safety of HRS9950 Tablets in Chronic Hepatitis B Patients Who Are Virologically Suppressed on Nucleoside or Nucleotide Analogues (NAs)

Chronic Hepatitis B

China
IlDong Pharmaceutical Co Ltd

Completed

Study to Assess the Antiviral Activity and Safety Endpoints for the Treatment of Besifovir 150mg Compared to Tenofovir 300mg in Chronic Hepatitis B Patients Who Have Resistance to Nucleoside Analogues (HBV)

Chronic Hepatitis B

Korea, Republic of
Xingfei Pan

Enrolling by invitation

Efficacy and Adverse Effects of Nucleoside Analogues (TDF/LDT) in Preventing Mother-to-child Transmission of HBV

Chronic Hepatitis b | Women

China
Tasly Tianjin Biopharmaceutical Co., Ltd.

Unknown

Safety and Efficacy of Therapeutic Hepatitis B Adenovirus Injection (T101) Combined With Nucleoside (Acid) Analogues in Chronic Hepatitis B Patients

Hepatitis B Virus (HBV)

China
Henlix, Inc

Unknown

Evaluate the Efficacy and Safety of HLX10 in Chronic Hepatitis B Patients

Hepatitis B, Chronic

Taiwan
F-star Therapeutics, Inc.
PRA Health Sciences

Terminated

Evaluating the Safety and Efficacy of Inarigivir in Non-cirrhotic, Hepatitis B e Antigen-negative Subjects Infected With HBV Virus and Receiving or Stopping Treatment With a NUC Inhibitor

Hepatitis B | Hepatitis B, Chronic | HBV

Canada, United Kingdom
University of Colorado, Denver
National Institute of Allergy and Infectious Diseases (NIAID); University of...

Completed

Effect of Gender and HIV Infection on Zidovudine and Lamivudine Pharmacokinetics

HIV

United States
Beijing Ditan Hospital

Unknown

A Cohort Study on Long-term Clinical Outcomes of Antiviral Therapy in Patients With Chronic Hepatitis B and Cirrhosis

Chronic Hepatitis b

China
Germans Trias i Pujol Hospital
Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la...

Completed

Study to Determine the Pharmacokinetic Behavior of Antiretroviral Drugs in Patients Infected by HIV

HIV Infections

Spain
Seng Gee Lim
Singapore General Hospital; Tan Tock Seng Hospital; Changi General Hospital

Unknown

Halting Nucleoside Analogues in Chronic Hepatitis B (HALT-NUCS)

Chronic Hepatitis B

Singapore
Seng Gee Lim
Merck Sharp & Dohme LLC; Singapore General Hospital; Tan Tock Seng Hospital; Changi... and other collaborators

Completed

Efficacy of Switching or Adding Pegylated Interferon in Chronic Hepatitis B Patients on Long Term Oral Antiviral Therapy (SWAP)

Chronic Hepatitis B

Singapore
Beijing Ditan Hospital

Unknown

Cohort Study of Clinical Outcomes in Chronic HBV Infection Patients With Low HBsAg Under Unplanned Intervention

Chronic Hepatitis B Infection

China
Seng Gee Lim
National Medical Research Council (NMRC), Singapore; Singapore Clinical Research...

Unknown

Tenofovir Versus Tenofovir + Telbivudine for Chronic Hepatitis B (DUAL)

Chronic Hepatitis B

Singapore
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID); Merck Sharp... and other collaborators

Completed

A5288/MULTI-OCTAVE: Management Using Latest Technologies to Optimize Combination Therapy After Viral Failure (MULTI-OCTAVE)

HIV-1 Infection

Kenya, Brazil, South Africa, Uganda, Zimbabwe, India, Malawi, Haiti, Thailand, Peru
Third Affiliated Hospital, Sun Yat-Sen University
Peking University; First People's Hospital of Foshan; Shenzhen Third People's...

Unknown

The Optimizing Treatment of PegIFN Alfa in HBeAg-negative CHB Patients With Low Level HBsAg

Chronic Hepatitis B

China
Asociacion para el Estudio de las Enfermedades...
Merck Sharp & Dohme LLC

Completed

Bitherapy With the Combination of Raltegravir and Darunavir (BIRDi) (BIRDi)

HIV/AIDS | Comorbidities

Spain
King Abdullah International Medical Research Center
Hoffmann-La Roche

Unknown

To Study the Effect of Adding on Pegylated Interferon (PEG-INF) Therapy for Patients Diagnosed With Chronic Hepatitis B (RC14/055)

Hepatitis B

Saudi Arabia
Beijing Ditan Hospital

Unknown

The Changes of Cytokines During Antiviral Therapy

Chronic Hepatitis B Infection

China
Beijing Ditan Hospital

Unknown

The Changes of Treg Cells Frequency and Function During Antiviral Therapy

Chronic Hepatitis B Infection

China
Beijing Ditan Hospital

Unknown

The Changes of Natural Killer Cells Frequency and Function During Antiviral Therapy

Chronic Hepatitis B Infection

China
Beijing Ditan Hospital

Unknown

The Changes of CD8+T Cells Frequency and Function During Antiviral Therapy

Chronic Hepatitis B Infection

China
Yao Xie

Unknown

The Changes of CD4+T Cells Frequency and Function During Antiviral Therapy

Chronic Hepatitis B Infection

China
Hoffmann-La Roche

Terminated

An Observational Study of Pegasys (Peginterferon Alfa-2a) in Patients With Chronic Hepatitis B Who Have Failed Antiviral Treatment With Nucleoside (Nucleotide) Analogues

Hepatitis B, Chronic

Poland
St Vincent's Hospital Melbourne
National Health and Medical Research Council, Australia

Unknown

Determinants of Virological Response After Discontinuation of Nucleoside Analogue Therapy in Hepatitis B Patients (STOP)

Chronic Hepatitis B.

Australia
Beijing Ditan Hospital

Unknown

Efficacy of Peginterferon Alpha 2a Therapy in Chronic Hepatitis B Patients Being Treated With Nucleoside(Acid) Analogues

Chronic Hepatitis B

China
University Hospital, Limoges

Completed

Assessment and Monitoring of Renal Proximal Tubular Tolerance of Nucleoside and Nucleotide Analogues Using Early Screening Tools in Patients Chronically Mono-infected With Hepatitis B Virus (HBVSECURE)

Hepatitis B | Renal Failure With Tubular Necrosis

France
Hoffmann-La Roche

Completed

A Study of Early Immunologic Response in Asian Patients With Chronic Hepatitis B, Treated With Pegasys (Peginterferon Alfa-2a (40KD)), Nucleoside Analogues, or Both

Hepatitis B, Chronic

Taiwan, United States, New Zealand, Singapore
Fundación Pública Andaluza Progreso y Salud

Completed

Retrospective Observational Study to Define HBsAg Loss With or Without Seroconversion to antiHBs in Patients With Chronic Hepatitis by B Virus Treated With Nucleoside/Nucleotide Analogs

Chronic Hepatitis B Treated With Nucleoside/Nucleotide Analogues

Spain
Beijing Ditan Hospital

Unknown

The Effect of Anti-viral Drugs Used in Late Pregnancy on Long-term Development of Children

the Safety of Anti-viral Drugs Used in Late Pregnancy
Fundacion SEIMC-GESIDA
Abbott

Completed

Treatment of HIV/HCV Coinfection With Peg-IFN and Ribavirin in Patients Receiving ART Monotherapy With Lopinavir/r (PEKARI)

HIV Infections | HIV/HCV Co-infection

Spain
Northwestern University
Abbott

Completed

SNAP: Switching Nucleoside Analogues Protocol - Lipoatrophy and Mitochondrial Function

HIV Infection

United States
Hospital de Calella

Completed

Study to Evaluate the Replacement of Reverse Transcriptase Nucleoside/Nucleotide Inhibitors by Nevirapine in Patients on Triple Treatment With Analogues Only

HIV Infections

Spain
National Institute of Diabetes and Digestive and...

Completed

Lamivudine for Chronic Hepatitis B

Chronic Hepatitis B | Glomerulonephritis | Polyarteritis Nodosa | Chronic Hepatitis D

United States
RSUP Fatmawati

Not yet recruiting

Ketoacid Analogues Intradialytic Effect on Inflammation

Hemodialysis Complication

Indonesia
MedSIR
Stemline Therapeutics, Inc.

Not yet recruiting

Elacestrant + Everolimus in Patients ER+/HER2-, ESR1mut, Advanced Breast Cancer Progressing to ET and CDK4/6i. (ADELA)

Advanced Breast Cancer | ER-positive Breast Cancer | HER2-negative Breast Cancer | ESR1 Gene Mutation
Novartis Pharmaceuticals

Not yet recruiting

NEPC Study: An Exploratory Safety and Efficacy Study With PSMA, SSTR2 and GRPR Targeted Radioligand Therapy in Metastatic Neuroendocrine Prostate Cancer.

Metastatic Neuroendocrine Prostate Cancer
Wageningen University

Recruiting

The EXPLAIN Study: Exploring Plant-Based Meat Analogues for Their Impact on Health (EXPLAIN)

Blood Pressure | Cardiometabolic Health

Netherlands

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