Search clinical trials for: off-label use

Total 20804 results

American Society of Clinical Oncology
Bristol-Myers Squibb; Eli Lilly and Company; Bayer; Merck Sharp & Dohme LLC; Pfizer; AstraZene... and other collaborators

Recruiting

TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer (TAPUR)

Lymphoma, Non-Hodgkin | Multiple Myeloma | Advanced Solid Tumors

United States
University Hospital, Toulouse

Completed

The RITAI Cohort: An Observational Study on Rituximab Off-label Use for Auto-immune Disorders (RITAI)

Cryoglobulinemia | Cold Agglutinin Disease | Pemphigus | Auto-immune Thrombocytopenic Purpura | Hemolytic Auto-immune Anaemia

France
Federal University of São Paulo

Unknown

Efficacy and Safety of Low-dose Oral Isotretinoin for Seborrhea

Quality of Life | Seborrheic Dermatitis | Seborrhea

Brazil
Regeneron Pharmaceuticals

Not yet recruiting

An Observational Study to Investigate the Use of Aflibercept 8 mg to Treat Adult Patients With Neovascular Age-Related Macular Degeneration (nAMD) and Diabetic Macular Edema (DME) in a Real-World Setting (SPECTRUM-US)

Visual Impairment | Diabetic Macular Edema (DME) | Neovascular Age-related Macular Degeneration (nAMD) | Wet Age-related Macular Degeneration (AMD)
Washington University School of Medicine
United States Agency for International Development (USAID); University of Ghana

Not yet recruiting

Peanut-based School Meals in Rural Ghana to Improve Attendance and Retention (PEANUT-SMART)

School Feeding Programs | Child Nutrition | School Attendance | School Dropouts | School Enrollment

Ghana
University Hospital, Ghent
Belgium Health Care Knowledge Centre

Not yet recruiting

Proactive TDM Versus Standard Use of Biologics in Psoriasis (HELIOS)

Psoriasis Vulgaris

Belgium
Center of Implantology, Oral and Maxillofacial...

Recruiting

Adjunctive Use of Dermal Matrix to Compensate Dimensional Changes in the Reconstructive Therapy of Peri-implantitis

Peri-Implantitis

Spain
Essen Biotech

Not yet recruiting

Investigation Into the Use of BAH243 Lentiviral Vector for Gene Therapy in Treating Sickle Cell Disease (BAH243)

Sickle Cell Disease | Sickle-Cell Disease With Crisis

China
Aelis Farma
National Institute on Drug Abuse (NIDA)

Not yet recruiting

Drug-Drug Interaction Between THC and AEF0117 (DDI)

Cannabis Abuse
Assiut University

Not yet recruiting

Result Of Use Of Wide Awake Local Anaesthesia In Fixation Of Ankle Fractures

Local Anesthesis
University of Chicago

Not yet recruiting

Development of a Mobile Health Intervention for Electronic Cigarette Use Among Young Adults (EQUIP)

Cigarette Smoking | Tobacco Products | Electronic Nicotine Delivery Systems
University of Pittsburgh

Not yet recruiting

The Use of Remote Monitoring to Improve Patient-Reported Outcomes and Readmission Rates Following Radical Cystectomy

Quality of Life | Bladder Cancer

United States
Mahidol University
Health Systems Research Institute; The Heart Association of Thailand

Not yet recruiting

COhort of antithrOmbotic Use and cLinical Outcomes in Patients With Atrial Fibrillation (COOL-AF) Phase 2

Atrial Fibrillation

Thailand
Medical University of South Carolina
National Institute on Drug Abuse (NIDA)

Not yet recruiting

A Brief Intervention for Cannabis Use

Cannabis Use Disorder
Massachusetts General Hospital
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Not yet recruiting

12-Step Facilitation/MET/CBT (InTEGRA) vs. MET/CBT for Youth With Alcohol and Other Drug Use Disorder: A Multisite RCT (InTEGRA)

Alcohol Use Disorder | Cannabis Use Disorder

United States
Universidad de Almeria

Not yet recruiting

Use of GI BIOTICS 100B UFC to Improve Intestinal Health in Older Adults (GIBIOTICS)

Gut Microbiota | Strength | Gut Health | Intestinal Inflammation | Digestive System

Spain
McMaster University

Not yet recruiting

Randomized Trial to Evaluate the Usefulness of Mental Health e-Learning

Depression | Anxiety
Médecins du Monde
University of Bristol; PATH; UNITAID; Burnet Institute; Population Services International and other collaborators

Not yet recruiting

Low Dead-space Injecting Equipment Distribution Program for People Who Inject Drugs in Low- and Middle-income Countries

Hepatitis | Hiv | Drug Use
IR Technology, LLC

Not yet recruiting

Clinical Trial of the invisaRED® IR REHAB Device When Used as an Adjunctive Therapy for Nociceptive Musculoskeletal Pain

Musculoskeletal Pain | Nociceptive Pain
Hacettepe University

Recruiting

Use of Plantar Flexion Resistant Ankle-Foot Orthosis in Stroke Patients With Genurecurvatum Gait

Chronic Stroke

Turkey
Peking University First Hospital

Recruiting

Establishment of a Multidimensional Prediction Model for the Natural Course of VHL Disease-related Renal Cell Carcinoma

Renal Cell Carcinoma | VHL Syndrome

China
Boston University
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Not yet recruiting

Online Intervention for Transgender/Nonbinary Young Adults' Experiences With Alcohol and Romantic Relationships

Depression, Anxiety | Alcohol Use, Unspecified | Relationship, Social | Transgenderism

United States
mAbxience Research S.L.

Recruiting

A Study Investigating the Safety, Absorption, and Elimination of MB04, a New Compound That May Potentially be Used in the Treatment of Autoimmune Disorders (MB04-A-01-23)

Healthy Volunteers

Netherlands
Dong-A ST Co., Ltd.

Not yet recruiting

A Study to Evaluate Safety, Tolerability, and PK of DA-7503 in Healthy Adult and Elderly Participants

Healthy

Korea, Republic of
Jack Rubinstein

Not yet recruiting

Effects of Remote Cardiac Ischemic Preconditioning

Effects of Tefillin Use on Markers of Preconditioning

United States
Hannover Medical School
Boehringer Ingelheim

Not yet recruiting

Study of Empagliflozin in Patients With Autosomal Dominant Polycystic Kidney Disease (EMPA-PKD) (EMPA-PKD)

Autosomal Dominant Polycystic Kidney
GRIN Therapeutics, Inc.

Recruiting

A Study of Radiprodil on Safety, Tolerability, Pharmacokinetics, and Effect on Seizures and Behavioral Symptoms in Patients With TSC or FCD Type II

Tuberous Sclerosis Complex | Focal Cortical Dysplasia

Spain, United Kingdom, Australia, Belgium, Canada, Italy, Poland
Université de Sherbrooke

Recruiting

Cyclosporine and Intense Pulsed Light for Dry Eye in Contact Lens Users (CycliP)

Dry Eye | Contact Lens Complication

Canada
University of Limerick

Recruiting

A Physiotherapy-led Disease-agnostic Telerehabilitation Programme for People With Chronic Health Conditions

Chronic Conditions, Multiple

Ireland
Mustafa Kemal University

Recruiting

Stress Ball Use in Patients Undergoing Coronary Angiography

Pain

Turkey
Universitätsklinikum Köln

Not yet recruiting

Investigation of the Audible ICD Alert Tone

Implantable Defibrillator User

Germany
Coloplast A/S

Recruiting

Investigation of a New Rectal Catheter for Users of Transanal Irrigation

Bowel Management

Denmark
Vanderbilt University Medical Center

Recruiting

Network-Targeted Neuromodulation for Nicotine Dependence in Schizophrenia

Schizophrenia | Nicotine Dependence

United States
Suzhou Kerui Medical Technology Co., Ltd

Not yet recruiting

A Clinical Trial to Evaluate the Safety and Efficacy of Single-use Fibrous Ring Sutures for the Suture of Fibrous Ring Incision After Nucleus Pulposus Removal

Intervertebral Disc Disorder
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); New Mexico State University; National Cancer...

Not yet recruiting

EQQUAL-NM for the Promotion of Smoking Cessation in Sexual and Gender Minority Young Adults in New Mexico

Cigarette Smoking-Related Carcinoma

United States
Hutchmed

Not yet recruiting

A Clinical Study of HMPL-506 in Patients With Hematological Malignancies

Hematological Malignancies
London Health Sciences Centre
Western University

Not yet recruiting

Use of 81 vs 325mg of ASA in Treatment of BCVI

Carotid Artery Injuries | Traumatic Injury | Vertebral Artery Injury
University Hospital "Sestre Milosrdnice"

Not yet recruiting

The Impact of Rhinoplasty Approach and Used Autologous Cartilage Grafts on the Nasal Skin-soft Tissue Envelope Metabolism

Rhinoplasty | Nasal Skin-soft Tissue Envelope Metabolism | Lactic Acid | Autologous Cartilage Grafting
Ain Shams University

Not yet recruiting

The Use of Lung US, Fluoroscopy and Auscultation to Confirm Proper Positioning of Left Sided DLT : A Comparative Study

Endotracheal Tube Wrongly Placed During Anesthetic Procedure
Istituto Ortopedico Rizzoli

Not yet recruiting

FAldini Sport Total Joint Arthroplasty-Knee II (FAST-K II)

Knee Osteoarthritis
Indivior Inc.

Not yet recruiting

Proof of Concept and Dose-ranging Study of INDV-2000 in Individuals With Moderate to Severe Opioid Use Disorder

Opioid Use Disorder
Cairo University

Not yet recruiting

Antibiotic Use and Resistance KAP Among Dental Interns

Antibiotic Side Effect | Antibiotic Resistant Infection
Prisma Health-Upstate
National Institute on Drug Abuse (NIDA); Clemson University

Recruiting

Development, Refinement, and Validation of a Peer Support Specialist Checklist for Individuals With Opioid Use Disorder / STAMPS: South Carolina Buprenorphine Treatment Initiation, Adherence, and Retention Utilizing Mobile Health Units and Peer Support Specialists

Opioid Use Disorder

United States
Fondazione Policlinico Universitario Agostino Gemelli...

Not yet recruiting

HYPERTESSA "HyperTessa User Experience Study (HTUX)"

Hypertension

Italy
Hospices Civils de Lyon

Not yet recruiting

Peer Support in Alcohol Dependence (PEERSIAD)

Alcohol Use Disorder

France
VA Office of Research and Development

Not yet recruiting

Personalized Approach Bias Modification in Heavy Drinking Veterans With Mild to Moderate Traumatic Brain Injury (TABM)

Alcohol Use Disorder | Mild-Moderate Traumatic Brain Injury

United States
Wayne State University

Not yet recruiting

Warrior CARE: Cannabis Behavioral Health (CBH)

Suicide | Post Traumatic Stress Disorder | Cannabis Use | Veterans | Marijuana

United States
Mayo Clinic
National Cancer Institute (NCI)

Not yet recruiting

Photoradiation With Verteporfin to Facilitate Immunologic Activity of Pembrolizumab in Unresectable, Locally Advance or Metastatic Pancreatic Cancer

Stage II Pancreatic Cancer AJCC v8 | Stage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Metastatic Pancreatic Adenocarcinoma | Locally Advanced Pancreatic Adenocarcinoma | Unresectable Pancreatic Adenocarcinoma

United States
McGill University Health Centre/Research Institute...

Recruiting

The Feasibility and Clinical Utility of the Use of Virtual Reality for the Management of Pediatric Dental Anxiety

Dental Anxiety | Behavior | Children, Only

Canada
HALEON

Not yet recruiting

A Real-World Evidence Study to Evaluate the Effects of Voltaren Use on Mobility and Quality of Life in Participants With Knee Osteoarthritis Pain

Pain

Search clinical trials for: off-label use

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Germany

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations