Search clinical trials for: oncology, cancer, tumour, neoplasm, anticancer drug, food effect, area under the curve, pharmacokine

Total 246831 results

AstraZeneca

Completed

Study to Assess the Blood Levels and Safety of Olaparib in Patients With Advanced Solid Tumours and Normal Liver Function or Mild or Moderate Liver Impairment

Solid Tumours

France, United Kingdom, Czechia, Korea, Republic of, Netherlands
AstraZeneca

Completed

Study to Assess the Blood Levels and Safety of Olaparib in Patients With Advanced Solid Tumours and Normal or Impaired Kidney Function

Solid Tumours

Belgium, France, Netherlands, United Kingdom, Denmark
AstraZeneca

Completed

To Assess the Effect of Itraconazole (a CYP3A4 Inhibitor) on the Pharmacokinetics of Olaparib, and the Effect of Olaparib on QT Interval Following Oral Dosing of a Tablet Formulation to Patients With Advanced Solid Tumours

Solid Tumours

Belgium, Denmark, United Kingdom, Netherlands
AstraZeneca

Completed

To Determine the Effect of Food on the Pharmacokinetics of Olaparib and the Effect of Olaparib on QT Interval Following Oral Dosing of a Tablet Formulation in Patients With Advanced Solid Tumours

Solid Tumours

Denmark, Belgium, United Kingdom, Netherlands
AstraZeneca

Completed

D081AC00001 Food Interaction With Olaparib Capsule in Patients With Solid Tumours

Solid Tumours

Belgium, United Kingdom, Netherlands
AstraZeneca

Completed

Study to Assess the Blood Levels and Safety of AZD9291 in Patients With Advanced Solid Tumours and Normal Liver Function or Mild or Moderate Liver Impairment

Solid Tumours

United States, Spain, Belgium, France, Korea, Republic of, United Kingdom
Novartis Pharmaceuticals

Not yet recruiting

Two-period Crossover Study to Demonstrate the Comparability of Pharmacokinetics of Subcutaneous Ianalumab Between 2mL Auto-injector/2mL PFS with1mL Pre-filled Syringe in Adult Participants With Autoimmune Disease

Rheumatoid Arthritis | Systemic Lupus Erythematosus | Sjögrens Disease
Pfizer

Recruiting

A Study for Two Tablet Forms of The Study Medicine (PF-07220060) in Healthy Adults

Healthy Participants

United States
University Hospital, Basel, Switzerland

Completed

Probability of Optimal Target Attainment of Amikacin in Patients With Febrile Neutropenia During Treatment for a Hematological Disorder

Febrile Neutropenia (FN)

Switzerland
Abion Inc

Completed

To Evaluate the Safety, Pharmacokinetic and the Effect of Food After Administration of ABN401 in Healthy Adult Volunteers

Solid Tumor

Korea, Republic of
VIST - Faculty of Applied Sciences
Tosla d.o.o.; Slovenian Research and Innovation Agency

Enrolling by invitation

The Effect of 24-week Dietary Intake of Food Supplements on Hair (TO-HAIR)

Hair Loss | Hair Thinning

Slovenia
AstraZeneca

Completed

Study to Determine the Effect of Food on the Blood Levels of AZD9291 Following Oral Dosing of a Tablet Formulation in Patients With Non-Small Cell Lung Cancer

Advanced Non Small Cell Lung Cancer | Advanced (Inoperable) Non Small Cell Lung Cancer

France, Korea, Republic of, United Kingdom, Spain
EA Pharma Co., Ltd.

Completed

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, Bioavailability, and Food-effects of EA1080 in Healthy Caucasian and Japanese Male Participants

Healthy Volunteers

United Kingdom
Bristol-Myers Squibb

Withdrawn

A Study to Evaluate the Effect of Food on the Drug Levels of BMS-986196 in Healthy Adult Participants

Healthy Adult Volunteers
Radiation Therapy Oncology Group
National Cancer Institute (NCI); NRG Oncology

Active, not recruiting

Hormone Therapy, Radiation Therapy, and Steroid 17alpha-monooxygenase TAK-700 in Treating Patients With High-Risk Prostate Cancer

Prostate Cancer

United States, Canada
TYK Medicines, Inc

Completed

A Study to Assess the Effect of Food on the Pharmacokinetics of TY-9591 in Healthy Volunteers

Healthy Volunteers

China
Cingulate Therapeutics

Completed

Fed-Fast Crossover Study to Assess the Effect of Food With CTx-1301 in Healthy Subjects (Fed-Fast)

Healthy Volunteers in Fed and Fasted State

United States
Pfizer

Completed

Evaluation of the Relative Bioavailability of Bosutinib Capsules Under Fed Condition and Estimation of Food Effect on Orally Administered Bosutinib Capsule

Healthy Participants

Belgium
Hoffmann-La Roche

Completed

A Study to Investigate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Food Effect of RO6953958 in Healthy Participants

Mental Disorders | Neurodevelopmental Disorders | Autism Spectrum Disorder | Autistic Disorder | Child Development Disorders, Pervasive

United Kingdom
Agios Pharmaceuticals, Inc.

Completed

A Study to Compare the Relative Bioavailability of Two AG-881 Formulations and Evaluate the Effect of Food and Omeprazole on the Pharmacokinetics of AG-881

Healthy Volunteers

United States
Clarus Therapeutics, Inc.
Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center

Completed

Pharmacokinetic Study of Oral Testosterone (T) Ester Formulations in Hypogonadal Men

Hypogonadism

United States
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Bioequivalence Study Of Gabapentin Between Tablet And Liquid Formulation And The Food Effect Study Of Liquid Formulation

Healthy

Singapore
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single Ascending Doses of ACT-1004-1239 in Healthy Male Subjects

Healthy

United States
Korea Otsuka Pharmaceutical Co., Ltd.

Completed

To Evaluate Food Effect on the Pharmacokinetics of Rebamipide in Healthy Volunteers

Healthy Volunteers

Korea, Republic of
AstraZeneca

Completed

To Assess Safety and Effect of Olaparib on the Pharmacokinetics of Anastrozole, Letrozole & Tamoxifen, and Their Effect on Olaparib, in Patients With Advanced Solid Cancer

Solid Tumours

Belgium, Denmark, France, United Kingdom, Netherlands
IVFarma LLC
NADIM LLC

Completed

The Safety and Pharmacokinetics of Primapur and Gonal-f

Pharmacokinetics | Absorption | Area Under Curve

Russian Federation
Sun Yat-sen University

Completed

Chemoembolization With or Without Mixing the Chemotherapy With Lipiodol for Unresectable HCC

Hepatocellular Carcinoma

China
Pfizer

Completed

A Study To Understand Safety And Plasma Concentrations Of PF-06669571 During And Following The Oral Administration Of Single And Multiple Doses Of PF-06669571 In Healthy Volunteers Under Fasted And Fed Conditions

Healthy

United States
EA Pharma Co., Ltd.

Completed

Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AJM347 in Healthy Male Caucasian and Japanese Subjects in the Fasted and Fed State

Healthy Participants

United Kingdom
Idorsia Pharmaceuticals Ltd.

Completed

A Clinical Study to Investigate the Potential Interactions Between Food and ACT-541468 and Between ACT-541468 and Midazolam

Healthy Subjects

Germany
AstraZeneca
Quintiles, Inc.

Completed

Phase I Study to Assess the Effect of Food on AZD1775 Pharmacokinetics in Patients With Advanced Solid Tumours

Solid Tumours

France, United Kingdom, Netherlands
North-West University, South Africa
Global Alliance for Improved Nutrition; Unilever R&D; DSM Ltd

Completed

Randomized Controlled Trial in South Africa Comparing the Efficacy of Complementary Food Products on Child Growth (TSWAKA)

Malnutrition

South Africa
Millennium Pharmaceuticals, Inc.

Completed

Pharmacokinetics Study of Oral IXAZOMIB in Participants With Advanced Nonhematologic Malignancies or Lymphoma

Lymphoma | Nonhematologic Malignancies

United States
National Institute of Allergy and Infectious Diseases...

Terminated

Hormone Replacement Therapy and Anti-HIV Drugs in HIV-Infected, Postmenopausal Women

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

Effects of Ribavirin on Zidovudine or Stavudine

HIV Infections | Hepatitis C

United States
Astellas Pharma Europe B.V.

Completed

A Study to Assess the Safety, Tolerability and Effects of Single and Multiple Ascending Doses of ASP1707 in Healthy Male and Pre-menopausal Female Subjects, Including a Comparison of the Effects Under Fasted and Fed Conditions in Healthy Young Male Subjects

Pharmacokinetics of ASP1707 | Pharmacodynamics of ASP1707

France
Lundbeck LLC

Withdrawn

An Open-Label, Single and Multiple Oral Dose Pharmacokinetic Study of Vigabatrin in Infants With Infantile Spasms

Infantile Spasms
University of Pittsburgh
American Society for Metabolic and Bariatric Surgery

Completed

The Effect of Gastric Bypass on the Pharmacokinetics of Serotonin Reuptake Inhibitors

Depression | Anxiety Disorder | Gastric Bypass

United States
University Hospital Freiburg
Novartis

Completed

Pharmacokinetics of Two Extended-Release Formulations of Methylphenidate in Children With Attention Deficit Hyperactivity Disorder (ADHD) (MPH-Kinetics)

Attention Deficit Hyperactivity Disorder

Germany
Jeil Pharmaceutical Co., Ltd.

Recruiting

To Evaluate the Safety, Pharmacokinetic Characteristics and the Effect of Food After Administration of JLP-2004

Healthy

Korea, Republic of
Uppsala University
University of Turku; Bielefeld University; Vivo international e.V.; The Swedish... and other collaborators

Not yet recruiting

Transforming Health and Resilience In Vulnerable Environments: Mental Health, Psychosocial Support, and Climate-Smart Farming in Nakivale (THRIVE)

Malnutrition | Psychological Distress | Mental Health | Malnutrition, Child | Dietary Deficiency
Changhai Hospital
Shanghai 10th People's Hospital; Ruijin Hospital; Shanghai Ninth People's Hospital... and other collaborators

Not yet recruiting

Real-World Clinical Study on the Efficacy of Vibrating Capsule (Vibrabot Capsule) for Chronic Functional Constipation (RWS-VC)

Clinical Study | Chronic Functional Constipation

China
The University of Texas Medical Branch, Galveston

Recruiting

Weighted Blanket to Treat Anxiety Related to Trying New Foods the Pediatric Population (Food Anxiety)

Anxiety State | Avoidant Restrictive Food Intake Disorder | Picky Eating | Food Neophobia

United States
Celgene

Not yet recruiting

Study to Evaluate Safety, Drug Levels, Food and Relative Bioavailability of BMS-986365 in Healthy Adult Male Participants

Healthy Participants

United States
Unilever R&D
Atlantia Food Clinical Trials

Not yet recruiting

A Randomised, Double-blind, Placebo-controlled, Crossover Study to Evaluate the Effects of a Food Ingredient on Self-reported Stress in Healthy Adults

Stress

Ireland
Maastricht University Medical Center

Not yet recruiting

Three Channel Food Concept: the Effect Meal Service on Food Intake During Hospitalization

Protein-Energy Malnutrition | Nutrition Poor

Netherlands
Changchun GeneScience Pharmaceutical Co., Ltd.

Recruiting

A Phase I Clinical Study Evaluating the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Multiple Oral Dose Escalation of GS1-144 Tablets and the Effects of Food on the Pharmacokinetics of GS1-144 in a Chinese Population

Healthy Volunteer | Vasomotor System; Labile

China
Fore Biotherapeutics

Recruiting

A Study of the Effects of Food and Cobicistat on Plixorafenib Pharmacokinetics in Healthy Volunteers.

Healthy Volunteer

United States
University of Florida

Not yet recruiting

Examining the Impact of High-protein Oral Supplement With Liposomal Curcumin on Inflammation Markers and Oxidative Stress in Adults Undergoing Hemodialysis.

Chronic Kidney Disease 5D
International Food Policy Research Institute
UNICEF; Ethiopian Public Health Association

Not yet recruiting

Increasing the Coverage of Severe Acute Malnutrition (SAM) Treatment in Ethiopia (R-SWITCH)

Wasting | Malnutrition, Child | Acute Malnutrition, Severe

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