Search clinical trials for: open capsule

Total 12792 results

Bristol-Myers Squibb

Recruiting

A Study to Assess the Relative Bioavailability of 5 mg Mavacamten Opened Capsule Administered Via Nasogastric Tube Compared to Intact Oral 5 mg Mavacamten in Healthy Participants

Healthy Volunteers

United States
Kyowa Kirin Korea Co., Ltd.

Recruiting

Multicenter, Open, Prospective, 48 Weeks, Observational Study ,Evaluate the Safety and Efficacy of Nephoxil Capsule

Hyperphosphatemia

Korea, Republic of
Supernus Pharmaceuticals, Inc.

Recruiting

Open-label Safety and Efficacy of SPN-812 (Viloxazine Extended-release Capsule) in Adults With ADHD and Mood Symptoms

Attention-Deficit/Hyperactivity Disorder

United States
Hanita Lenses

Recruiting

Influence of CleaRing Open-capsule Device on Refractive Predictability in Cataract Patients (Part 2) (CleaRing)

Posterior Capsule Opacification

Israel
Carlos Roberto Simons-Linares

Recruiting

OPEN Versus InTact Capsule Proton Pump Inhibitors for the Treatment of Marginal Ulcers (OPEN-IT)

Marginal Ulcer

United States
Morten Steen Kvistholm Jensen
Odense University Hospital; Zealand University Hospital; Rigshospitalet, Denmark and other collaborators

Recruiting

Treatment Effects of Bisoprolol and Verapamil in Symptomatic Patients With Non-obstructive Hypertrophic Cardiomyopathy (TEMPO II)

Non-obstructive Hypertrophic Cardiomyopathy

Denmark
European Institute of Oncology

Recruiting

Metronomic Temozolomide in Unfit NENs Patients Metronomic Temozolomide in Unfit Patients With Advanced Neuroendocrine Neoplasms (NENs): MeTe Study (MeTe)

Frailty | Neuroendocrine Tumors | Chemotherapy Effect

Italy
National Institute of Allergy and Infectious Diseases...
SIGA Technologies

Recruiting

Study of Tecovirimat for Human Monkeypox Virus (STOMP)

Monkeypox | MPOX

United States, Puerto Rico, Brazil, South Africa, Argentina, Mexico, Japan, Thailand, Peru
Novartis Pharmaceuticals

Recruiting

A 24-week Prospective, Open-label, Multicenter, Single-arm rPMS Study in Real-world Setting for Atectura®

Asthma

Korea, Republic of
Fulcrum Therapeutics

Recruiting

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of FTX-6058

Sickle Cell Disease | Sickle Cell Anemia

United States
Centre Hospitalier Universitaire, Amiens

Recruiting

Comparison of Azathioprine to Methotrexate in Combination Therapy With Adalimumab in Crohn's Disease: an Open-label Randomized Controlled Trial (COMET)

Crohn Disease | Methotrexate | Azathioprine

France
Shandong University

Recruiting

A Multicenter Randomized Open-label Study of Diammonium Glycyrrhizinate Enteric-coated Capsule Plus DXM Versus DXM in Treatment of ITP

Immune Thrombocytopenia

China
Ain Shams University

Recruiting

Preoperative Coadministration of Low-concentration Carbohydrate and Nitrates Loading vs Low- Concentration Carbohydrate Loading Alone in Patients Undergoing Open Gynecological Surgeries

Length of Hospital Stay

Egypt
Hanita Lenses

Recruiting

Influence of Clearing Open-capsule Device on Refractive Predictability in Cataract Patients

Cataract

Israel
Tongji Hospital

Recruiting

Open-label Study of Neuraminidase Inhibitor Treatment in STEMI Patients

ST Elevation Myocardial Infarction | STEMI

China
Cure HHT
University of North Carolina

Not yet recruiting

Pazopanib for the Treatment of Epistaxis in Hereditary Hemorrhagic Telangiectasia

Epistaxis | Hereditary Hemorrhagic Telangiectasia
Minneamrita Therapeutics LLC
Translational Drug Development

Recruiting

A Phase 1, Multi-Center, Open-Label, Dose-Escalation, Safety, Pharmacokinetic, and Pharmacodynamic Study of Minnelide™ Capsules Given Alone or in Combination With Protein-Bound Paclitaxel in Patients With Advanced Solid Tumors (Minnelide 101)

Breast Cancer | Gastric Cancer | Pancreatic Cancer | Solid Tumor | Advanced Cancer | Colo-rectal Cancer | Prostate Cancer Metastatic | Solid Carcinoma | Solid Carcinoma of Stomach | Cancer of Stomach

United States
Beyond Batten Disease Foundation
Theranexus

Active, not recruiting

An Open-label Safety, Pharmacokinetic, and Efficacy Study of Miglustat for the Treatment of CLN3 Disease

Batten Disease

United States
Albireo

Completed

An Open Label, Single-dose, Single Period ADME Study of A4250 in Healthy Subjects

Primary Biliary Cirrhosis | Alagille Syndrome | Progressive Familial Intrahepatic Cholestasis | Orphan Cholestatic Liver Diseases

United Kingdom
Supernus Pharmaceuticals, Inc.

Completed

Open-label Long-Term Safety and Efficacy of SPN-812 (Viloxazine Extended-release Capsule) in Adults With ADHD

Attention-Deficit/Hyperactivity Disorder

United States
Xiromed LLC
Laboratorios Liconsa

Completed

Open Label Study to Assess the Effect of Patient Use and Robustness of Tiotropium 18ug Inhalation Powder, Hard Capsule,Zephir Inhaler Device

COPD

United States, India
Yuhan Corporation

Completed

A Randomized, Active-controlled, Parallel, Open-label, Multicenter, Phase 4 Study to Compare the Efficacy and Safety of Pregabalin Sustained Release Tablet and Pregabalin Immediate Release Capsule in Type II Diabetic Patients With Peripheral Neuropathic Pain

Diabetes Mellitus, Type 2 | Neuropathic Pain

Korea, Republic of
Mirum Pharmaceuticals, Inc.

Completed

Open Label, Continuation Study of Cholic Acid in Subjects With Inborn Errors of Bile Acid Synthesis

Bile Acid Synthesis Defect

United States
Institut für Klinische Krebsforschung IKF GmbH...
Merck Sharp & Dohme LLC; Medizinische Hochschule Hannover, Germany, Prof. Dr...

Active, not recruiting

Pembrolizumab and Lenvatinib in Patients With Advanced HCC Who Are Refractory to Atezolizumab and Bevacizumab/ IO-based Therapy

Hepatocellular Carcinoma

Germany
Karuna Therapeutics

Active, not recruiting

An Open-label Study to Assess the Long-term Safety, Tolerability, and Efficacy of KarXT in Adult Patients With Schizophrenia (EMERGENT-5)

Schizophrenia

United States
Timothy L. Brown
National Highway Traffic Safety Administration (NHTSA); Cognitive Research... and other collaborators

Completed

Validation of the Drug Impaired Driving Scenario (DIDS) on the CRCDS-miniSim (PDID)

Driving Under the Influence | Driving Behavior

United States
Karuna Therapeutics

Terminated

An Open-label Study to Assess the Long-term Safety, Tolerability, Effectiveness, and Durability of Effect of KarXT in Patients With DSM-5 Diagnosis of Schizophrenia (PENNANT)

Schizophrenia

United States
Otsuka Pharmaceutical Development & Commercialization...

Completed

Open-label, Single-dose Trial to Assess the Pharmacokinetics of Centanafadine Extended-release Capsules in Pediatric Participants With Attention-deficit Hyperactivity Disorder (ADHD)

Attention Deficit Hyperactivity Disorder

United States
Diurnal Limited
National Institutes of Health (NIH)

Withdrawn

Open-label Comparison of Chronocort® Versus Standard Glucocorticoid Replacement Therapy (RESTORE)

Congenital Adrenal Hyperplasia

United States
AstraZeneca

Completed

Phase III Open Label Study of MEDI 4736 With/Without Tremelimumab Versus Standard of Care (SOC) in Recurrent/Metastatic Head and Neck Cancer (KESTREL)

Squamous Cell Carcinoma of the Head and Neck

United States, Canada, France, Italy, Spain, United Kingdom, Poland, Taiwan, Thailand, Vietnam, Belgium, Germany, Korea, Republic of, Brazil, India, Japan, Philippines, Russian Federation, Austria, Ukraine, Greece, Slovakia, Romania
AstraZeneca
Parexel

Terminated

Evaluation of AZD8154 Concentrations in Blood

Asthma

Germany
UCB PHARMA Inc. (US)

Completed

This Trial, Evaluating the Long-term Safety and Tolerability of Brivaracetam Will Provide Subjects Suffering From Epilepsy, Who May Have Benefited From Brivaracetam as Adjunctive Treatment, the Opportunity to Receive Open Label Brivaracetam Treatment

Epilepsy

United States, Australia, Brazil, Canada, India, Mexico
KemPharm, Inc.

Completed

KP415 Open-Label Safety Study in Children (6-12 Years of Age) With ADHD

ADHD

United States
Virginia Commonwealth University
National Institutes of Health (NIH); Medical College of Wisconsin; OpenBiome; Hunter...

Completed

Oral Fecal Transplant in Cirrhosis

Hepatic Encephalopathy | Cirrhosis, Liver

United States
University of Oxford
Pfizer

Completed

A Multicentre Open-label Two-arm Randomised Superiority Clinical Trial of Azithromycin Versus Usual Care In Ambulatory COVID19 (ATOMIC2) (ATOMIC2)

COVID-19

United Kingdom
Major Extremity Trauma Research Consortium

Completed

Improving Pain Management and Long Term Outcomes Following High Energy Orthopedic Trauma (Pain Study) (PAIN)

Orthopaedic Fractures

United States
Sihuan Pharmaceutical Holdings Group Ltd.

Unknown

Open-label Study to Assess the Absorption, Metabolism, Excretion, and Mass Balance of a Single Oral Dose of [14C]-20 mg/100 μCi Anaprazole Sodium Enteric-coated Capsule in Healthy Adult Male Subjects

Healthy Male Volunteers
Microbiome Health Research Institute
University of Wisconsin, Madison; Indiana University

Completed

A Trial of Encapsulated Fecal Microbiota for Vancomycin Resistant Enterococcus Decolonization

Antibiotic Resistant Strain

United States
Zhongshan Ophthalmic Center, Sun Yat-sen University

Unknown

Effect of Ginkgo Biloba Capsule on Visual Function of Primary Open-angle Glaucoma With Blood Stasis Syndrome

Primary Open Angle Glaucoma | Drug Effect

China
University of California, Los Angeles
OpenBiome; Finch Research and Development LLC.

Withdrawn

Pilot Study Using Oral Capsule FMT to Decolonize GI CRE

Enterobacteriaceae Infections | Fecal Microbiota Transplantation
Eunice Kennedy Shriver National Institute of Child...
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National...

Completed

Effects of Colchicine in Non-Diabetic Adults With Metabolic Syndrome

Obesity | Metabolic Disease

United States
Medtronic - MITG

Completed

A Pilot and Feasibility Study to Evaluate Capsule Endoscopy (MA-79)

Upper Gastrointestinal Hemorrhage

Hong Kong, Israel
Astellas Pharma Europe Ltd.

Terminated

A Paediatric, Open, Follow up Study With Modigraf Examining Safety and Efficacy in de Novo Allograft Recipients (PROGRESSION)

Liver Transplantation | Kidney Transplantation | Heart Transplantation

Belgium, France, Germany, Poland, Spain, United Kingdom
The First Affiliated Hospital with Nanjing Medical...

Unknown

Lenalidomide, Rituximab, Gemcitabine, Oxaliplatin and Dexamethasone in Relapse and Refractory DLBCL (R2-GOD)

Diffuse Large B-cell Lymphoma Recurrent | Diffuse Large B Cell Lymphoma Refractory

China
AstraZeneca

Completed

A Study to Evaluate Bioavailability and Food Effect of Selumetinib (AZD6244) in Healthy Male Participants

Healthy Participants | Neurofibromatosis Type 1 (NF1)-Related Plexiform Neurofibromas (PNs)

United States
Allama Iqbal Open University Islamabad
King Edward Medical University

Completed

Role of Omega-3 Polyunsaturated Fatty Acid in the Management of Major Depressive Disorder.

Role of Omega-3 Polyunsaturated Fatty Acid in the Management of Major Depressive Disorder: A Randomized Controlled Trial

Pakistan
Horizon Pharma USA, Inc.

Completed

Open-Label, Safety and Superior Effectiveness Study of Cysteamine Bitartrate Delayed-Release Capsules (RP103) in Cystinosis

Cystinosis

France, United States, United Kingdom, Belgium, Italy, Netherlands
Herlev Hospital
GENIS

Terminated

Gemcitabine and Capecitabine With or Without T-ChOS as Adjuvant Therapy for Patients With Resected Pancreatic Cancer (CHIPAC)

Pancreatic Cancer

Denmark
Medical University of South Carolina
National Institute on Drug Abuse (NIDA); American Academy of Child Adolescent...

Completed

An Open-Label Trial of N-Acetylcysteine in Cannabis Dependent Adolescents (NAC MJ Pilot)

Cannabis Dependence

United States
Ultragenyx Pharmaceutical Inc

Completed

An Open Label Phase 2 Extension Study of Higher Dose Sialic Acid-Extended Release (SA-ER) Tablets and Sialic Acid-Immediate Release (SA-IR) Capsules in Patients With Glucosamine (UDP-N-acetyl)-2-Epimerase (GNE) Myopathy

GNE Myopathy | Hereditary Inclusion Body Myopathy (HIBM)

United States, Israel

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