Search clinical trials for: open label pilot study

Total 126419 results

Sunnybrook Health Sciences Centre

Recruiting

Accelerated, Theta-burst Stimulation for the Treatment of Post-concussion Syndrome - Open-label Pilot Study

Post-Concussion Syndrome

Canada
Sir Ganga Ram Hospital

Recruiting

Vegetarian Versus Non Vegetarian Based Diet in the Recurrence of Hepatic Encephalopathy in Patients With Cirrhosis: An Open Label Pilot Study

Hepatic Encephalopathy

India
Lindsey Russell, MD
Napo Pharmaceuticals, Inc.

Not yet recruiting

Open-Label Pilot Study With Crofelemer in Patients With Short Bowel Syndrome

Short Bowel Syndrome

United States
Chinese University of Hong Kong

Recruiting

Open-label Pilot Study Synbiotic Treatment for Autism Spectrum Disorder

Anxiety | Autism Spectrum Disorder

Hong Kong
M.D. Anderson Cancer Center

Recruiting

A Pilot, Open-Label Study of Luspatercept for Patients With Lower Risk Myelodysplastic Syndromes (MDS)

Myelodysplastic Syndromes

United States
University of Stellenbosch
University of Rochester; Fogarty International Center of the National Institute...

Recruiting

A Pilot Study of Metformin to Reduce Cerebrovascular Dysfunction in Participants With HIV and Metabolic Syndrome. (SMART)

Metabolic Syndrome | HIV Seropositivity

South Africa
University Hospital, Tours

Recruiting

Finger Food, Pleasure at Your Fingertips: Randomized Pilot Study, Open-label and Parallel Groups (PLAID)

Undernutrition | Elderly Person

France
liberDi Ltd.

Not yet recruiting

A Prospective, Open-label, Multi-center Pilot Study to Evaluate the Safety, Feasibility and Usability of the IDA (CSP-027-21)

Chronic Kidney Disease Stage V
Donald Jeffrey Newport
Sage Therapeutics

Recruiting

An Open Label Pilot Study of IV Brexanolone for the Treatment of Post-Traumatic Stress Disorder

Post-Traumatic Stress Disorder

United States
Li Zhang, MD

Recruiting

An Open Label, Multicenter Phase 2 Study of Durvalumab (MEDI4736) + Olaparib as Maintenance Therapy in Chinese

Small Cell Lung Cancer | Lung Cancer | Durvalumab

China
Centre for Addiction and Mental Health

Recruiting

Neural Correlates of Ketamine's Anti-suicidal Effects in Bipolar Depression (DEEPP)

Suicidality | Bipolar Disorder (BD)

Canada
NovoCure GmbH
Merck Sharp & Dohme LLC

Recruiting

EF-36/Keynote B36: A Pilot, Randomized, Open-label Study of Tumor Treating Fields (TTFields, 150 kHz) Concomitant With Pembrolizumab for First Line Treatment of Advanced or Metastatic Non-small Cell Lung Cancer (KEYNOTE B36)

Non-small Cell Lung Cancer

United States
Universitair Ziekenhuis Brussel

Recruiting

Neuromodulation in the Elderly Depressed: a Brain Imaging Pilot Study

Depressive Disorder, Treatment-Resistant | Old Age

Belgium
NovoCure Ltd.

Recruiting

Open-Label Pilot Study of OPTUNE® With High Density Transducer Arrays for the Treatment of Recurrent GBM

Glioblastoma Multiforme

Czechia
Istituto Auxologico Italiano

Active, not recruiting

Pilot Open Label Study With Commercial Supplementation in Healthy Subjects (AUXNUTRIMMUN)

Supportive Care

Italy
Lykos Therapeutics

Completed

Randomized, Double-blind, Active Placebo-Controlled Pilot Study of MDMA-assisted Psychotherapy in People With Chronic PTSD

Posttraumatic Stress Disorder (PTSD)

Israel
Medical University of South Carolina
National Center of Neuromodulation for Rehabilitation

Completed

Plasticity Using Stimulation and Habit: A Pilot Open-label rTMS Study for MCI (PUSH-Pilot)

Mild Cognitive Impairment

United States
Centre for Addiction and Mental Health

Completed

Intranasal Ketamine in Ultra-REsistant Depression (SURE-ECT Non Responders) (SURE-ECT)

Depression

Canada
Hospital Universitari de Bellvitge

Completed

Feasibility and Effect of a Multidisciplinary Telematics Approach for Chronic Non-specific Low Back Pain: a Randomized, Open-label, Controlled, Pilot Clinical Trial. Study Protocol

Low Back Pain

Spain
Virginia Commonwealth University
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Completed

Open Label Pilot Study of Perampanel for the Treatment of Alcohol Use Disorder

Alcohol Disorders

United States
Sunnybrook Health Sciences Centre

Completed

An Open Label, Single-Centre, Pilot Study of Everolimus With EBRT for the Treatment of mNET Liver Metastasis (EBRT)

Carcinoma, Neuroendocrine

Canada
Tonix Pharmaceuticals, Inc.

Withdrawn

An Open-Label, Randomized Pilot Study Comparing the Safety of a Single Dose of TNX-1300 to Usual Care (UC) Alone for the Treatment of Signs and Symptoms of Acute Cocaine Intoxication in Male Emergency Department (ED) Subjects

Cocaine Intoxication

United States
Takeda
Ovid Therapeutics Inc.

Completed

A Multicenter, Open-label, Pilot Study of Soticlestat (TAK-935/OV935) in Participants With 15Q Duplication Syndrome (Dup 15q) or Cyclin-Dependent Kinase-Like 5 (CDKL5) Deficiency Disorder (ARCADE STUDY)

15q Duplication Syndrome | CDKL5 Deficiency Disease

United States
Icahn School of Medicine at Mount Sinai

Completed

Apremilast in the Treatment of Central Centrifugal Cicatricial Alopecia (CCCA)

Central Centrifugal Cicatricial Alopecia

United States
Steeve Provencher
Resverlogix Corp

Completed

Apabetalone for Pulmonary Arterial Hypertension: a Pilot Study (APPRoAcH-p)

Pulmonary Arterial Hypertension

Canada
University of Maryland, Baltimore

Withdrawn

Long Acting Paliperidone in Dually Diagnosed People With Schizophrenia: An Open-label Pilot Study

Schizophrenia

United States
Oregon Health and Science University
Pfizer

Completed

Tofacitinib Hypothesis-generating, Pilot Study for Corticosteroid-Dependent Sarcoidosis

Sarcoidosis | Sarcoidosis, Pulmonary | Sarcoidosis Lung

United States
National Institute of Allergy and Infectious Diseases...
Glaxo Wellcome

Completed

Treatment of Acyclovir-Resistant Mucocutaneous Herpes Simplex Disease in Patients With AIDS: Open Label Pilot Study of Topical Trifluridine

HIV Infections | Herpes Simplex

United States
Hoffmann-La Roche

Terminated

A Study of Balovaptan in Adults With Autism Spectrum Disorder With a 2-Year Open-Label Extension

Autism Spectrum Disorder

United States, Canada, France, Italy, Spain, United Kingdom
Massachusetts General Hospital

Withdrawn

A Pilot Open Labeled Study of Tacrolimus in Alzheimer's Disease.

Alzheimer Disease | Mild Cognitive Impairment
MyoKardia, Inc.

Completed

A Phase 2 Open-label Pilot Study Evaluating MYK-461 in Subjects With Symptomatic Hypertrophic Cardiomyopathy and Left Ventricular Outflow Tract Obstruction (PIONEER-HCM)

Cardiomyopathy, Hypertrophic Obstructive | Left Ventricular Outflow Tract Obstruction

United States
Boston Scientific Corporation

Completed

An Open-label, Single-dose Pilot Study to Evaluate Varisolve® (Polidocanol Endovenous Microfoam (PEM)) 0.125% [0.2%] for Varicose Veins

Varicose Veins

United States
New York State Psychiatric Institute

Completed

An Open-Label Pilot Study of Sublocade as Treatment for Opiate Use Disorder

Opioid-use Disorder

United States
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

A Pilot Open-Label Crossover Bioavailability Study of Celecoxib in Healthy Volunteers

Healthy Volunteers

Singapore
Spire, Inc.
ResMed

Completed

An Exploratory, Observational, Non-interventional, Open Label, Remote Pilot Study to Assess Adherence in COPD Subjects

Severe Chronic Obstructive Pulmonary Disease | Moderate Chronic Obstructive Pulmonary Disease

United States
Samaritan Health Services

Completed

GlitazOne Treatment for Coronavirus HypoxiA, a Safety and Tolerability Open Label With Matching Cohort Pilot Study (GOTCHA)

Coronavirus Infection | Diabetes

United States
MedDay Pharmaceuticals SA

Completed

SERENDEM : MD1003 in Patients Suffering From Demyelinating Neuropathies, an Open Label Pilot Study

Charcot-Marie-Tooth Disease | Peripheral Neuropathy | Chronic Inflammatory Demyelinating Polyneuropathy | Charcot-Marie-Tooth Disease Type 1A | Charcot-Marie-Tooth Disease, Type 1B | Anti-MAG Neuropathy

France
Amgen

Completed

Open-Label,Single-Arm Pilot Study to Evaluate the Pharmacodynamics, Pharmacokinetics, Safety, and Preliminary Efficacy of CC1004 in Subjects With Severe Plaque Type Psoriasis (PSOR-001)

Psoriasis

United States
Hospital of Prato

Unknown

Baricitinib in Symptomatic Patients Infected by COVID-19: an Open-label, Pilot Study. (BARI-COVID)

Pharmacological Action

Italy
Fundacion SEIMC-GESIDA

Completed

A Phase IV, Open-label, Randomised, Pilot Clinical Trial Designed to Evaluate the Potential Neurotoxicity of Dolutegravir/Lamivudine/Abacavir in Neurosymptomatic HIV Patients and Its Reversibility After Switching to Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide. DREAM Study (DREAM)

HIV Infections

Spain
Chung-Ang University Hosptial, Chung-Ang University...

Completed

Pilot Study of Effect of Intravenous Lidocaine on Propofol Requirement in Facial Plastic Surgery

Anesthesia, Intravenous; Surgery, Plastic

Korea, Republic of
University Hospital, Montpellier

Completed

Post TAVI Coronary REVASCularisation Guided by Myocardial Perfusion Imaging: a Prospective Open Label Pilot Study: The REVASC-TAVI Study (REVASC-TAVI)

Stable Coronary Disease | Severe and Symptomatic Aortic Stenosis

France
Erasmus Medical Center

Completed

Autofluorescent Flavoprotein Imaging of Intraepidermal Nerve Fibers: a Pilot Study

Small Fiber Neuropathy

Netherlands
Lori Davis, MD
Merck Sharp & Dohme LLC; Forest Laboratories

Completed

An Open Label Pilot Study of Adjunctive Asenapine for the Treatment of Posttraumatic Stress Disorder

Posttraumatic Stress Disorder

United States
New York State Psychiatric Institute
National Institute on Drug Abuse (NIDA)

Completed

Open-Label Pilot Study of Lisdexamfetamine for Cocaine Dependence (Vyvance)

Cocaine Dependence

United States
New York State Psychiatric Institute

Completed

Open-Label Pilot Study of Guanfacine-Extended Release for the Treatment of Cannabis Dependence (GUAN)

Cannabis Dependence

United States
Annecto LLC
Holy Redeemer Hospital

Terminated

Pilot Study Using Transcranial Electrostimulation (TESA-HB) Therapy for the Treatment of Depressive Symptoms (TESAHBPilot)

Mild to Moderate Depression

United States
Psoriasis Treatment Center of Central New Jersey

Unknown

An Open-Label, Pilot Study to Evaluate the Efficacy of Narrowband Ultraviolet-B Phototherapy Three Times Weekly for Twelve Weeks in Moderate-to-Severe Psoriasis Patients

Psoriasis

United States
The Leeds Teaching Hospitals NHS Trust

Unknown

A Prospective, Open Label, Pilot Study of Patient OutcoMes Following Successful TriAl of High Frequency SpInal CorD Stimulation at 10kHz (HF10™) Leading to Permanent Implant Compared to Trial Failure and Standard CarE for the TreatmeNt of Persistent Low BACK Pain of Neuropathic Origin (Maiden Back)

Palliative Care

United Kingdom
Royal Free Hospital NHS Foundation Trust

Unknown

AlcoChange: An Open Label Pilot Study of Smartphone Monitoring for Alcoholic Liver Disease

Alcohol-Related Disorders

3

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