Search clinical trials for: open-label extension

Total 2159 results

Novartis Pharmaceuticals

Completed

CLCZ696B2319E1 OL Extension Study to Evaluate Long-term Safety of Sacubitril/Valsartan in Pediatric Patients With HF

Heart Failure

United States, Italy, Croatia, India, Japan, Poland, Spain, Taiwan, Austria, Korea, Republic of, Germany, Lebanon, Thailand, Canada, Bulgaria, Russian Federation, Turkey, Switzerland, Argentina, Hungary, Portugal, Finland, South Africa and more
Novartis Pharmaceuticals

Completed

Rainbow Extension Study (RainbowExt)

Retinopathy of Prematurity (ROP)

United States, Austria, Belgium, Croatia, Czechia, Denmark, Egypt, France, Germany, Greece, Hungary, India, Italy, Japan, Malaysia, Romania, Russian Federation, Saudi Arabia, Slovakia, Taiwan, Turkey, United Kingdom, Lithuania, Estonia
Dermavant Sciences GmbH
IQVIA Biotech

Completed

Long Term Extension Study of Tapinarof for Plaque Psoriasis in Adults (3003)

Plaque Psoriasis

United States, Canada
MedImmune LLC

Completed

MEDI2228 in Subjects With Relapsed/Refractory Multiple Myeloma (MEDI2228)

Relapsed/Refractory Multiple Myeloma

United States, Australia, Spain, Greece
Stealth BioTherapeutics Inc.

Terminated

A Trial to Evaluate Safety and Efficacy of Elamipretide Primary Mitochondrial Myopathy Followed by Open-Label Extension (MMPOWER-3)

Primary Mitochondrial Myopathy

United States, Germany, Canada, Italy, United Kingdom, Denmark, Hungary
Pfizer

Completed

Open Label Extension In Cancer Patients

Neoplasms | Bone Metastases

United States, Croatia, Slovakia, India, Poland, Austria, Bosnia and Herzegovina, Hungary, Korea, Republic of, Latvia
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Extension Study Of Long-Term Safety And Efficacy Of Pregabalin As Monotherapy (Lyrica) In Patients With Partial Seizures

Epilepsy

United States, Ukraine, Hong Kong, Czechia
GlaxoSmithKline

Completed

A Multi-center, Open-label Extension, Safety Study of Mepolizumab in Subjects With Hypereosinophilic Syndrome (HES) From Study 200622

Hypereosinophilic Syndrome

United States, Poland, Spain, France, Belgium, Germany, Argentina, Russian Federation, Mexico, Italy, Brazil, United Kingdom, Romania
Novartis Pharmaceuticals

Completed

A Placebo-controlled Study of Efficacy & Safety of 2 Trough-ranges of Everolimus as Adjunctive Therapy in Patients With Tuberous Sclerosis Complex (TSC) & Refractory Partial-onset Seizures (EXIST-3)

Tuberous Sclerosis Complex-associated Refractory Seizures

United States, Colombia, Belgium, France, Japan, Taiwan, Turkey, Spain, Thailand, Korea, Republic of, Australia, Hungary, United Kingdom, Canada, Norway, Germany, Italy, Russian Federation, Denmark, Argentina, Netherlands, Greece, P... and more
BioMarin Pharmaceutical

Terminated

A Study of the Safety, Tolerability & Efficacy of Long-term Administration of Drisapersen in US & Canadian Subjects

Muscular Dystrophies

United States, Canada
AbbVie (prior sponsor, Abbott)

Completed

Open-label Study of the Safety and Efficacy of Adalimumab in the Treatment of Hidradenitis Suppurativa (PIONEER (OLE))

Hidradenitis Suppurativa
GlaxoSmithKline

Terminated

Open-Label Extension Study Of Rosiglitazone XR As Adjunctive Therapy In Subjects With Mild-to-Moderate Alzheimers

Alzheimer's Disease

Australia, Spain, United States, Bulgaria, Germany, Belgium, Canada, Hong Kong, Korea, Republic of, Portugal, Argentina, Chile, Greece, Slovenia, Czechia, France, Hungary, Italy, South Africa, India, Sweden, Netherlands, Philippines, ... and more
GlaxoSmithKline

Terminated

Study Of Rosiglitazone XR In Subjects With Mild-to-Moderate Alzheimers

Alzheimer's Disease

United States, Bulgaria, Germany, Estonia, Korea, Republic of, China, Greece, Hungary, Russian Federation, Philippines, Austria, Chile, Mexico, Croatia, New Zealand, Peru, Puerto Rico, United Kingdom
Tonix Pharmaceuticals, Inc.

Completed

Open Label Extension Safety and Efficacy Study of TNX-102 SL Tablets in Military Related PTSD and Related Conditions (P202)

PTSD

United States
TetraLogic Pharmaceuticals

Completed

Birinapant With 5-azacitidine in MDS Subjects Who Are Naïve, Have Relapsed or Are Refractory to 5-azacitidine Therapy

Myelodysplastic Syndrome

United States
Pfizer

Terminated

A Phase 2 Extension Study To Enroll Subjects Who Were Enrolled In B5301001 Study

Hypertrophic Scars Resulting From Prior Breast Scar Revision Surgery

United States
GlaxoSmithKline

Completed

Long-term Extension Study Evaluating Extended Release Ropinirole XL (Formerly Referred to as Ropinirole CR) in Patients Who Already Completed Either Study 167 or 164

Parkinson Disease

United States
UCB Biopharma SRL

Not yet recruiting

An Open-label Extension Study to Evaluate Subcutaneous Zilucoplan in Pediatric Participants With Generalized Myasthenia Gravis (ziMyG+)

Generalized Myasthenia Gravis
Zydus Therapeutics Inc.

Not yet recruiting

Open-Label Extension Study of Saroglitazar Magnesium in Participants With Primary Biliary Cholangitis

Primary Biliary Cholangitis

United States, Turkey, Argentina
Biohaven Therapeutics Ltd.

Not yet recruiting

BHV-7000 Open-Label Extension Bipolar Mania Study

Bipolar Disorder
Supplement Formulators, Inc.
Compound Solutions Inc.

Recruiting

Effectiveness of a Butyrate Formulation and Butyrate + Polyphenol Formulation on Gut Health, Permeability and Associated Symptoms

Gut Health

United States
Ultragenyx Pharmaceutical Inc

Not yet recruiting

Long-term Extension of GTX-102 in Angelman Syndrome

Angelman Syndrome

United States, Australia, Canada, Germany, United Kingdom, Israel, France, Spain
Bruno Minotti
Roland Bingisser, Principal Investigator, Head of Emergency Department, University... and other collaborators

Not yet recruiting

Open-Label Placebo for Non-Specific Pain in the ED (OLP_EM)

Pain, Acute
Fudan University
The University of Hong Kong

Not yet recruiting

Impact of a Mock-up Fact-checking Extension on HPV Vaccine Misinformation: A Survey Experiment

HPV Vaccine

China
Takeda

Not yet recruiting

A Long-Term Extension Study of Vedolizumab in Children and Teenagers With Ulcerative Colitis (UC) or Crohn's Disease (CD)

Crohn's Disease | Ulcerative Colitis
Constellation Pharmaceuticals

Not yet recruiting

An Extension Study for Patients Previously Enrolled in Studies With Pelabresib

Solid Tumor | Hematologic Malignancy | Advanced Malignancies
The University of Texas Health Science Center,...
Brighter Bites and Humana Foundation

Not yet recruiting

Brighter Bites & University of Texas Physicians Produce Rx Extension: Evaluating the Effectiveness of a Prospective Clinical Nutrition Study With Produce Prescriptions

Obesity, Childhood

United States
McGill University Health Centre/Research Institute...
The Hospital for Sick Children; Canadian Institutes of Health Research (CIHR); Unity Health Toronto and other collaborators

Not yet recruiting

Patient Navigator Intervention for Migrant Children With Special Healthcare Needs Experiencing Care Transitions

Patient Navigation

Canada
University of California, San Francisco

Not yet recruiting

Open-label Placebo (COLP) for Pain in Adolescent Idiopathic Scoliosis (AIS) Surgery+Surgical Treatment of Idiopathic Scoliosis

Adolescent Idiopathic Scoliosis (AIS)

United States
University of Copenhagen
University of Southern Denmark; Danish Research Centre for Magnetic Resonance; Faculty of Health, Medicine and Life Sciences, Maastricht University and other collaborators

Recruiting

Effect of Sleep Extension on Overweight and Learning in Children (More2Sleep)

Child Behavior | Child Development | Child Obesity | Sleep Duration

Denmark
Novartis Pharmaceuticals

Recruiting

Open-label, Long-term Safety Study of Secukinumab in Polymyalgia Rheumatica (PMR) (REPLENISH-EXT)

Polymyalgia Rheumatica

Australia
Mustafa Kemal University

Recruiting

Comparison of Exercise Effects in Individuals With Flatfoot

Flat Foot [Pes Planus] (Acquired), Unspecified Foot

Turkey
Children's Hospital of Eastern Ontario

Not yet recruiting

PRecisiOn Microbiome Directed ExtensiOn of Anti-TNFα Crohn's Disease ThErapy in Children: The PROMOTE Trial (PROMOTE)

Inflammatory Bowel Diseases | Crohn Disease

Canada
University Hospital, Bordeaux

Recruiting

Fluid Responsiveness Evaluation by a Non-invasive Method in Children, Extended to PREterm Infants - FRENCH-PREMA (FRENCH-PREMA)

Premature Baby 26 to 32 Weeks | Premature Baby 33 to 36 Weeks

France
GB002, Inc.

Not yet recruiting

Open-label Extension Study of Seralutinib in Adult Subjects With PAH (PROSERA-EXT)

Pulmonary Arterial Hypertension

United States
PTC Therapeutics

Recruiting

An Extension Study to Evaluate the Long-Term Safety and Efficacy of PTC518 in Participants With Huntington's Disease (HD)

Huntington Disease

Australia, France, Germany, Netherlands, United Kingdom, Spain, Austria, Canada, Italy, New Zealand
University of Alabama, Tuscaloosa
University of Alabama at Birmingham

Recruiting

Community Stroke Self-management Program

Stroke | Blood Pressure

United States
NextPoint Therapeutics, Inc.

Recruiting

A Study of NPX887 for Participants With Solid Tumors Known to Express HHLA2/B7-H7

Metastatic Malignant Neoplasm

United States
New World Medical, Inc.

Not yet recruiting

An Extension Trial for Patients With Open-Angle Glaucoma Who Participated in the DF6-CL-20-01 Protocol.

Intraocular Pressure | Open Angle Glaucoma

Costa Rica
University of Minnesota

Recruiting

Project SHINE (Sleep Health INitiative for Equity): Culturally Informing a Sleep Extension Intervention for African American Adults

Obesity | Insufficient Sleep

United States
Cairo University

Recruiting

Effect of Combined Lumbar Traction and Repetitive Back Extension Exercise on H-reflex in Lumbosacral Radiculopathy

Lumbosacral Radiculopathy | McKenzie Derangement Syndrome

Egypt
Incyte Corporation

Recruiting

A Study to Evaluate the Long-Term Safety and Efficacy of Povorcitinib in Participants With Moderate to Severe Hidradenitis Suppurativa (STOP-HS LTE)

Hidradenitis Suppurativa (HS)

United States, Austria, Belgium, Canada, Germany, Poland, Spain, Australia, Denmark, France, United Kingdom, Japan, Bulgaria, Netherlands, Czechia, Greece, Italy
Debre Berhan University
University of South Africa

Not yet recruiting

Effect Of Health Extension Worker-Led Based Interventions on Improving Self-Management Behavior Among Diabetic Patients in Ethiopia (HEWL-SMB)

Diabetes Mellitus, Self-management Behavior and Glycosylated Hemoglobin Levels

Ethiopia
University of Utah

Recruiting

Effect of Sleep Extension on Ceramides in People With Overweight and Obesity

Sleep | Type 2 Diabetes | Sleep Deprivation | Overweight and Obesity | Insulin Sensitivity | Sleep Hygiene | Eating Habit | Lifestyle Factors | Insufficient Sleep Syndrome

United States
PharmAust Ltd
Macquarie University, Australia; Calvary Health Care Bethlehem

Recruiting

An Open Label Extension Study of Monepantel in Individuals With Motor Neurone Disease

Motor Neuron Disease

Australia
Hinova Pharmaceuticals Inc.

Recruiting

A Phase I Study to Assess the Safety, Pharmacokinetics, and Anti-Tumor Activity of Oral HP518 in mCRPC Patients

Metastatic Castration-resistant Prostate Cancer

China
Novartis Pharmaceuticals

Recruiting

Phase 3 Extension Study to Evaluate Long-term Safety of Ianalumab in Participants With Systemic Lupus Erythematosus (SIRIUS-SLE Extension). (SIRIUS-SLE LTE)

Systemic Lupus Erythematosus

Spain
University of Chicago

Recruiting

Sleep Extension or Regularity to Reduce Diabetes Risk in African American and Black Adults

Overweight or Obesity

United States
Innovent Biologics (Suzhou) Co. Ltd.

Recruiting

A Multicenter, Open-label Extension Study Evaluating the Efficacy and Safety of IBI311 in Subjects With Thyroid Eye Disease

Thyroid Eye Disease, TED

China
Sling Therapeutics, Inc.

Recruiting

A Phase 2b Extension Study of Two Doses of Linsitinib in Subjects With Active, Moderate to Severe Thyroid Eye Disease (TED)

Eye Diseases | Endocrine System Diseases | Thyroid Diseases | Thyroid Eye Disease | Graves Ophthalmopathy | Exophthalmos | Orbital Diseases | Thyroid Associated Ophthalmopathy | Graves Orbitopathy | Proptosis | IGF1R | Hashimoto

United States

Search clinical trials for: open-label extension

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