Search clinical trials for: oral therapeutic

Total 29079 results

Cerevel Therapeutics, LLC

Not yet recruiting

A Trial to Assess the Absorption, Metabolism, Excretion, and Mass Balance of [14C]-Darigabat After a Single Oral Dose in Healthy Male Participants

Healthy Participants

United States
Eilean Therapeutics

Recruiting

Study of Single and Multiple Ascending Doses of ZE46-0134 in Healthy Volunteers

AML

Australia
Universidad Miguel Hernandez de Elche
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la...

Not yet recruiting

Early Intervention With Therapeutic Exercise in Plantar Fasciopathy (PIPex-FP)

Plantar Fascitis

Spain
Centre Hospitalier Universitaire de Saint Etienne
Ministry of Health, France

Not yet recruiting

Therapeutic Effect of Hydroxychloroquine on Immunoglobulin A (IgA) Nephropathy Course QUIgAN Study (QUIgAN)

IgA Nephropathy

France
Nested Therapeutics, Inc

Recruiting

A Study to Investigate the Safety and Efficacy of NST-628 Oral Tablets in Subjects With Solid Tumors (NST-628)

Glioma | Melanoma | NSCLC | Oncology | Solid Tumor, Adult | MEK Mutation | RAF Gene Mutation | Ras (KRAS or NRAS) Gene Mutation | MAPK Pathway Gene Mutation

United States, Australia
Iama Therapeutics S.r.l.

Recruiting

IAMA-6 Oral Dose Study in Healthy Adults

Neurodevelopmental Disorders

Italy
Gerbera Therapeutics, Inc.

Not yet recruiting

A Study to Assess the Efficacy, Safety, and Tolerability of Oral NORA520 in Adults With Severe Postpartum Depression (NuMom)

Postpartum Depression | Depression, Postpartum | Postnatal Depression | Post-partum Depression | Post-Natal Depression

United States
Denali Therapeutics Inc.

Recruiting

A Phase 1, Open-label Study of the Absorption, Metabolism, and Excretion of [14C]-DNL343 Following a Single Oral Dose in Healthy Male Participants

Healthy Volunteers

United States
Biora Therapeutics, Inc.

Recruiting

BT-600 Single and Multiple Ascending Oral Doses in Healthy Adult Subjects

Healthy

United States
Istituti Clinici Scientifici Maugeri SpA
Società Italiana Cardiologia Ospedalità Accreditata (SICOA)

Recruiting

Therapeutic Strategy With Direct Oral Anticoagulants and Antiaggregant Drugs in Ischemic Heart Disease (PRODOAC)

Atrial Fibrillation

Italy
German Breast Group
GlaxoSmithKline; Stemline Therapeutics, Inc.

Not yet recruiting

Evaluating the Addition of Elacestrant (Oral SERD) to Niraparib (PARP-inhibitor) in Patients With Advanced/Metastatic HR+/HER2- Breast Cancer (ELEMENT)

BRCA1 Mutation | BRCA2 Mutation | PALB2 Gene Mutation | Hormone Receptor Positive HER-2 Negative Breast Cancer | Advanced or Metastatic Breast Cancer

Germany
University of Minnesota

Recruiting

Evaluation of an Oral Microbiota-based Therapeutic as a Treatment Option for PSC

Primary Sclerosing Cholangitis

United States
Wake Forest University Health Sciences

Not yet recruiting

Histidine Oral Supplementation as a Therapeutic Modality for Alzheimer's Disease

Alzheimer Disease

United States
University of Texas Southwestern Medical Center
assertio Therapeutics, Inc

Not yet recruiting

Intra-nasal Ketorolac for Acute Ureteral Stent-associated Pain Following Ureteroscopy for Stone Disease

Urolithiasis | Post Operative Pain | Ureter Calculi | Stent Complication

United States
Hillhurst Biopharmaceuticals, Inc.
National Heart, Lung, and Blood Institute (NHLBI)

Not yet recruiting

A Safety, Efficacy, and Pharmacokinetic (PK) Study of HBI-002, an Oral Carbon Monoxide (CO) Therapeutic, in Subjects With Sickle Cell Disease (SCD)

Anemia, Sickle Cell

United States
Peking University People's Hospital

Recruiting

Progesterone Therapeutic Regimen Plus Statins in Young Women With Early Endometrial Carcinoma and Atypical Endometrial Hyperplasia

Atypical Endometrial Hyperplasia and Endometrial Carcinoma Stage I

China
Memorial Sloan Kettering Cancer Center
Astellas Pharma US, Inc.; Corcept Therapeutics; Breast Cancer Research Foundation

Recruiting

A Study of Enzalutamide, Enzalutamide in Combination With Mifepristone, or Chemotherapy in People With Metastatic Breast Cancer

Metastatic Breast Cancer

United States
YourChoice Therapeutics, Inc.

Recruiting

First in Human Study Evaluating Single Ascending Oral Doses of YCT-529 in Healthy Males

Male Contraception

United Kingdom
ATXA Therapeutics Limited
Hammersmith Medicines Research

Recruiting

Safety, Pharmacokinetics (PK) and Relative Bioavailability of NTP42:KVA4 as a Solid Oral Dose

Healthy

United Kingdom
Hoffmann-La Roche

Recruiting

A Study to Evaluate Efficacy and Safety of Giredestrant Compared With Fulvestrant (Plus a CDK4/6 Inhibitor), in Participants With ER-Positive, HER2-Negative Advanced Breast Cancer Resistant to Adjuvant Endocrine Therapy (pionERA Breast Cancer)

Estrogen Receptor-Positive, HER2-Negative Advanced Breast Cancer

Belgium, Korea, Republic of, United States, Canada, China, Italy, France, Brazil, Australia, Argentina, Hong Kong, Portugal, Spain, Taiwan, India, Costa Rica, Israel, Thailand, Germany, New Zealand, Poland, Chile, Colombia, Guatemala, H...
Spero Therapeutics
GlaxoSmithKline

Recruiting

A Study of Oral Tebipenem Pivoxil Hydrobromide (TBP-PI-HBr) Compared to Intravenous Imipenem-cilastatin in Participants With Complicated Urinary Tract Infection (cUTI) or Acute Pyelonephritis (AP) (PIVOT-PO)

Urinary Tract Infection | Acute Pyelonephritis

Moldova, Republic of, Georgia, United States, Serbia, Bulgaria, Romania, South Africa, Bosnia and Herzegovina, Croatia, Hungary, Poland, Slovakia
Neumora Therapeutics, Inc.

Recruiting

Study to Assess the Effects of Oral NMRA-335140 in Participants With Major Depressive Disorder

Major Depressive Disorder

United States
Neumora Therapeutics, Inc.

Recruiting

Study to Assess the Effects of Oral NMRA-335140 Versus Placebo in Participants With Major Depressive Disorder

Major Depressive Disorder

United States, Canada
Al-Azhar University

Not yet recruiting

The Premedication Properties of Oral Melatonin in Pediatrics Undergoing Therapeutic Cardiac Catheterization

Anesthesia

Iraq
Neumora Therapeutics, Inc.

Recruiting

Study to Evaluate the Effects of Oral NMRA 335140 Versus Placebo in Participants With Major Depressive Disorder

Major Depressive Disorder

United States
Cara Therapeutics, Inc.

Recruiting

Study to Evaluate the Efficacy and Safety of Oral Difelikefalin for Moderate to Severe Pruritus in Subjects With Notalgia Paresthetica

Pruritus | Notalgia Paresthetica

United States, Poland, Spain, Canada, Germany
Flare Therapeutics Inc.

Recruiting

A Study of FX-909 in Patients With Advanced Solid Malignancies, Including Advanced Urothelial Carcinoma

Advanced Solid Tumors Cancer | Advanced Urothelial Carcinoma | Open Label | Oral Drug Administration

United States
Jinnah Postgraduate Medical Centre

Not yet recruiting

Efficacy of L-Ornithine L-Aspartate and Polyethylene Glycol in Cirrhotic Patients With Overt Hepatic Encephalopathy

Hepatic Encephalopathy Stage 2 | Hepatic Encephalopathy Stage 3 | Hepatic Encephalopathy Stage 4

Pakistan
Artios Pharma Ltd

Recruiting

Study of ART6043 in Advanced/Metastatic Solid Tumors Patients

Advanced Solid Tumor | Metastatic Solid Tumor

United States
Cognition Therapeutics

Recruiting

Study to Evaluate the Efficacy and Safety of Oral CT1812 in Participants With Geographic Atrophy (GA) Secondary to Dry Age-Related Macular Degeneration (AMD).

Age-Related Macular Degeneration

United States
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield; University of Cambridge; University of Newcastle Upon-Tyne and other collaborators

Recruiting

Pulmonary Hypertension: Intensification and Personalisation of Combination Rx (PHoenix)

Pulmonary Arterial Hypertension

United Kingdom
Shanghai Ninth People's Hospital Affiliated to...

Not yet recruiting

Elective vs Therapeutic Neck Dissection in Treatment of Patients With Clinical T1/2N1M0 Oral Squamous Cell Carcinoma

Oral Squamous Cell Carcinoma | Neck Dissection
Corcept Therapeutics

Recruiting

Study to Determine the Prevalence of Hypercortisolism in Patients With Type 2 Diabetes and Treatment With Korlym® (Mifepristone) (CATALYST)

Diabetes Mellitus, Type 2 | Hypercortisolism

United States
Arisan Therapeutics, Inc.
United States Department of Defense; Battelle Memorial Institute; The Defense...

Recruiting

A Study to Assess the Safety, Tolerability, and Pharmacokinetics of Oral ARN-75039 in Healthy Adult Subjects

Lassa Virus Infection

United States
Onconic Therapeutics Inc.

Not yet recruiting

Clinical Trial to Evaluate Food-Effects on Pharmacokinetics and Pharmacodynamics of Oral Single Dose of JP-1366 Tablet in Healthy Volunteers

Healthy

Korea, Republic of
Anthos Therapeutics, Inc.

Recruiting

Study to evaLuate the effIcacy and Safety of abeLacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral antiCoagulation (LILAC-TIMI 76) (LILAC-TIMI 76)

Atrial Fibrillation (AF)

United States, Canada, Israel, Japan, China, Brazil, Chile, United Kingdom, Bulgaria, Germany, Hungary, Italy, Poland, Romania, Spain, Czechia, Latvia, Mexico, India, Estonia
Far Eastern Memorial Hospital

Recruiting

Comparisons of the Therapeutic Effects of Dienogest and Danazol on Endometriosis

Endometriosis

Taiwan
Esperion Therapeutics, Inc.

Recruiting

A Phase 2 Clinical Study in Children With HeFH Aged 6 to 17 Treated Once Daily With Bempedoic Acid Oral Dosing (CLEAR Path 1)

Hypercholesterolemia

United States, Spain, Denmark, Canada, Netherlands, Germany
University of Southern California
Medical University of South Carolina; National Institute on Aging (NIA); Alzheimer... and other collaborators

Recruiting

Life's End Benefits of Cannabidiol and Tetrahydrocannabinol (LiBBY)

Dementia | Agitation

United States
Mirati Therapeutics Inc.

Recruiting

Combination Therapies With Adagrasib in Patients With Advanced NSCLC With KRAS G12C Mutation (202200050434)

Metastatic Lung Cancer | Advanced NSCLC

United States, Spain, Greece, Hungary, France, Italy, Poland
Rennes University Hospital

Recruiting

Microsampling Approach for Monitoring of Kinase Inhibitor Targeted Therapies (MISTIK)

Blood Concentrations of Nine Anti-cancer Drugs : Axitinib, Olaparib, regorafénib, Cabozantinib, Niraparib, Talazoparib, Palbociclib, Abemaciclib, Tucatinib

France
Sorrento Therapeutics, Inc.

Not yet recruiting

Study to Access Anti-CD38 Anibody Drug in Patients With Advanced Solid Tumors

Advanced Solid Tumor

United States
STORM Therapeutics LTD

Recruiting

Oral Administration of STC-15 in Subjects With Advanced Malignancies

Cancer | Advanced Solid Tumor | Advanced Cancer

United States
Fundamenta Therapeutics, Ltd.
The First Affiliated Hospital of Zhengzhou University

Not yet recruiting

Safety and Efficacy of ThisCART19A Bridging Hematopoietic Stem Cell Transplantation in Patients With Refractory or Relapsed B-cell Acute Lymphoblastic Leukemia

Allogeneic, CAR-T, Protein Sequestration, Non-gene Edited
National Institute of Allergy and Infectious Diseases...

Recruiting

Study of Oral TLR8 Agonist Selgantolimod on HBsAg in Participants With Both Chronic Hepatitis B and HIV

HIV Infections | Hepatitis B

Botswana, Thailand, United States, Zimbabwe, Haiti, Philippines, Brazil, Peru, South Africa, Uganda
Axsome Therapeutics, Inc.

Recruiting

Open-Label Study of AXS-07 for the Acute Treatment of Migraine in Adults With a Prior Inadequate Response to an Oral CGRP Inhibitor (EMERGE)

Migraine

United States
Cerevel Therapeutics, LLC

Recruiting

Positron Emission Tomography (PET) Trial to Evaluate Target Occupancy of CVL-354 at Kappa and Mu Opioid Receptors in Brain Following Oral Dosing

Opioid Use Disorder

United States
Monte Rosa Therapeutics, Inc

Recruiting

Study of Oral MRT-2359 in Selected Cancer Patients

NSCLC | Prostate Cancer | SCLC | DLBCL | High Grade Neuroendocrine Cancer | L-MYC and N-MYC Amplified Solid Tumors | NSCLC With High or Low L-MYC or N-MYC Expression | HR-positive, HER2-negative Breast Cancer

United States, Canada
National Institute of Allergy and Infectious Diseases...
SIGA Technologies

Recruiting

Study of Tecovirimat for Human Monkeypox Virus (STOMP)

Monkeypox | MPOX

United States, Puerto Rico, Brazil, South Africa, Argentina, Mexico, Japan, Thailand, Peru
Aminex Therapeutics, Inc.

Recruiting

Oral AMXT 1501 Dicaprate in Combination With IV DFMO

Melanoma | Cervical Cancer | Cancer | Breast Cancer | Head and Neck Cancer | Gastric Cancer | Colorectal Cancer | Esophageal Cancer | Solid Tumor | Endometrial Cancer | Advanced Cancer | Diffuse Midline Glioma, H3 K27M-Mutant | Papillary Thyroid Cancer | Solid Carcinoma | Mesotheliomas Pleural | Glioma, Malignant | Ovary Cancer and other conditions

United States, Australia

Search clinical trials for: oral therapeutic

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