Search clinical trials for: pharmacokinetic interactions

Total 13225 results

Shouyao Holdings (Beijing) Co. LTD

Not yet recruiting

A Study to Evaluate the Effect of Itraconazole and Rifampicin on the Pharmacokinetics of SY-5007 in Healthy Subjects

Healthy Subjects

China
dr. Tom van der Hulle
Leiden University Medical Center

Recruiting

The Pharmacological Effects of Using Cabozantinib With a Light Breakfast (Skippy 1)

Renal Cell Carcinoma

Netherlands
JW Pharmaceutical

Completed

To Evaluate the Safety and Pharmacokinetic Interactions in Healthy Volunteers

Healthy

Korea, Republic of
University of Alabama at Birmingham
Merck Sharp & Dohme LLC; University of Washington; Wits Reproductive Health and...

Active, not recruiting

Evaluation of Pharmacokinetic Drug-drug Interactions Between Hormonal Contraceptives and Doravirine-containing ART Among Women Living With HIV in South Africa (EPIC)

HIV Infections | Contraception | Drug-drug Interaction

South Africa
AstraZeneca
Parexel

Completed

Study to Assess the Effect of Sodium Zirconium Cyclosilicate on the Pharmacokinetics of Tacrolimus and Cyclosporin in Healthy Subjects

Hyperkalaemia

Germany
Vertex Pharmaceuticals Incorporated

Completed

A Study to Evaluate the Pharmacokinetic Drug-drug Interactions Between VX-548, Midazolam, and Digoxin

Pain

United States
Pop Test Oncology LLC
Baylor College of Medicine; Michael E. DeBakey VA Medical Center; Congressionally... and other collaborators

Completed

Effects of Ethanol on the Pharmacokinetics of PT-150 (Formerly ORG34517) (PT150 PK Study)

Potential Treatment for Alcohol Dependence-Alcohol Interaction

United States
National Institutes of Health Clinical Center (CC)

Completed

Impact of Steady State Cobicistat and Darunavir/Cobicistat on the Pharmacokinetics and Pharmacodynamics of Oral Anticoagulants (Rivaroxaban, Apixaban) in Health Volunteers

Healthy Volunteers

United States
Sumitomo Pharma America, Inc.

Completed

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Drug Interaction Potential of Napabucasin in Healthy Volunteers

Drug-drug Interactions

United States
Seoul National University Bundang Hospital

Enrolling by invitation

A Drug-drug Interaction Study to Evaluate the Effect of Rifampicin on the Pharmacokinetics of Methotrexate in Elderly Subjects

Drug Interactions

Korea, Republic of
National Institutes of Health Clinical Center (CC)

Completed

Impact of Weekly Administration of Rifapentine and Isoniazid on Steady State Pharmacokinetics of Tenofovir Alafenamide in Healthy Volunteers (YODA)

Healthy Volunteers

United States
LI YAN

Completed

Effect of Azole/Echinocandin Use on Tacrolimus Pharmacokinetics

Kidney Transplant Patients

China
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Withdrawn

Pharmacokinetic Interactions of ENG Subdermal Implants With Long-Acting Cabotegravir (CAB-LA) and LA Rilpivirine (RPV-LA) (CARLA)

HIV-1-infection
Il-Yang Pharm. Co., Ltd.

Completed

Study to Evaluate Pharmacokinetic Drug Interactions and Safety of Ilaprazole and Aceclofenac

Drug Interaction Potentiation

Korea, Republic of
Il-Yang Pharm. Co., Ltd.

Completed

Study to Evaluate Pharmacokinetic Drug Interactions and Safety of Naproxen, Aceclofenac, Celecoxib and Ilaprazole

Drug Interaction Potentiation

Korea, Republic of
Washington State University
National Center for Complementary and Integrative Health (NCCIH)

Active, not recruiting

Clinical Evaluation of the Pharmacokinetic Goldenseal-Metformin Interaction in Diabetic Patients

Diabetes Mellitus, Type 2 | Interaction, Adverse Herb-Drug

United States
Washington State University
National Center for Complementary and Integrative Health (NCCIH)

Completed

Assessing Goldenseal-drug Interactions Using a Probe Drug Cocktail Approach

Interaction Drug Food

United States
Hanmi Pharmaceutical Company Limited

Completed

Pharmacokinetic Drug Interactions Between HGP1607 and HGP1501

Healthy Male Volunteers

Korea, Republic of
JW Pharmaceutical

Completed

To Evaluate the Pharmacokinetic Interactions and Safety in Healthy Volunteers

Healthy

Korea, Republic of
JW Pharmaceutical

Completed

To Evaluate the Pharmacokinetic Drug Interactions, Safety and Drug Tolerance in Healthy Volunteers

Healthy

Korea, Republic of
Calliditas Therapeutics AB

Completed

Study to Evaluate the Pharmacokinetics and Drug-Drug Interactions of Setanaxib in Healthy Adult Male and Female Subjects

Phase 1

France
Xspray Pharma AB
Axis Clinicals Limited

Completed

Evaluating the Effects of Omeprazole on the Pharmacokinetics of XS004 (Dasatinib) Tablets in Healthy Adult Subjects Under Fasting Conditions

Pharmacokinetics | Drug Interactions

United States
Aurinia Pharmaceuticals Inc.

Completed

Drug-Drug Interaction Study to Investigate Effects of Voclosporin on Pharmacokinetics of Simvastatin (Statin-DDI)

Drug-drug Interaction

United States
University of North Carolina, Chapel Hill
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Prospective Cohort Evaluating Pregnancy Rates, PK Interactions Among HIV+ Women on EFV Initiating LNG Implant or DMPA (FP-ART)

HIV Infections

Malawi
Viriom

Completed

Pharmacokinetics Study to Evaluate Drug-Drug Interactions and Safety of Elpida® in Co-Administration With Other Drugs

HIV-1-infection

Russian Federation
National Institute of Allergy and Infectious Diseases...

Completed

A Study to Assess the Effect of Concomitant Administration of Fluconazole on the Clinical Pharmacokinetics of Methadone

HIV Infections | Candidiasis

United States
National Institute of Allergy and Infectious Diseases...

Completed

Safety and Tolerance of Zidovudine With Probenecid and the Effect of Probenecid on Zidovudine Pharmacokinetics Over Four Weeks

HIV Infections

United States
Shionogi

Completed

Evaluation of Safety, Tolerability, Pharmacokinetics, Drug-Drug and Food Interactions of Single and Multiple Doses of S-648414 in Healthy Adults

Healthy Volunteer

United States, Japan
National Institute of Allergy and Infectious Diseases...

Completed

Drug Interactions of Amprenavir and Efavirenz, in Combination With a Second Protease Inhibitor, in HIV-Negative Volunteers

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

Interactions Between HIV Protease Inhibitors and Calcium Channel Blockers

Cardiovascular Diseases | HIV Infections | Hypertension

United States
National Institute of Allergy and Infectious Diseases...
AIDS Clinical Trials Group

Completed

Drug Interactions Between Lopinavir/Ritonavir and Oral or Patch Contraceptives in HIV Infected Women

HIV Infections | Pregnancy

United States, Puerto Rico
National Institute of Allergy and Infectious Diseases...

Completed

Effect of Fluconazole, Clarithromycin, and Rifabutin on the Pharmacokinetics of Sulfamethoxazole-Trimethoprim and Dapsone and Their Hydroxylamine Metabolites

HIV Infections | Bacterial Infections | Mycoses

United States
National Institute of Allergy and Infectious Diseases...
Bristol-Myers Squibb; ICN Pharmaceuticals

Completed

A Phase I Open-Label Study of the Safety, Tolerance, and Pharmacokinetic Interactions of Combination Didanosine and Ribavirin in HIV-Positive Individuals

HIV Infections

United States
Yale University
Gilead Sciences

Withdrawn

A Study of the Pharmacokinetic and Pharmacodynamic Interactions Between Bictegravir, Tenofovir Alafenamide and Rifapentine in Healthy Adult Subjects

Tuberculosis | Hiv

United States
Makerere University
University of Turin, Italy; University of Liverpool; European and Developing...

Completed

Drug-drug Interactions Between Remdesivir and Commonly Used Antiretroviral Therapy (RemTLAR)

HIV/AIDS | Ebola

Uganda
Celgene

Completed

A Study to Evaluate Potential Cytochrome P450 and Transporter Protein Interactions With CC-99677

Healthy Volunteer

United Kingdom
Acerta Pharma BV

Completed

A Study to Evaluate Safety, Pharmacokinetics, Pharmacodynamics, Food Effects, and Drug-drug Interactions of ACP-196 in Healthy Participants

Healthy Participants

United States
Emalex Biosciences Inc.
Syneos Health; Nuventra

Terminated

Drug-Drug Interaction Study to Evaluate the Effects of Ecopipam on the Pharmacokinetics of Multiple Substrates

Drug-Interactions

United States
Cambridge University Hospitals NHS Foundation Trust
AstraZeneca; University of Cambridge

Terminated

A Study of the Pharmacokinetic and Pharmacodynamic Responses in Healthy and Altered Human Cardiovascular Systems (PRIME)

Drug-Related Side Effects and Adverse Reactions | Cardiovascular System Disease

United Kingdom
Bayer

Completed

Study in Healthy Adult Male Participants to Gather Information How the Human Body Absorbs, Distributes and Excretes the Study Drug Selitrectinib Including the Effect of the Interaction of Food With the Study Drug on the Human Body

Solid Tumors Harboring NTRK Fusion

Germany
Hanlim Pharm. Co., Ltd.

Unknown

The Study of Pharmacokinetic Interactions Between HL237 and Tacrolimus

Healthy Male Volunteers

Korea, Republic of
GlaxoSmithKline

Completed

A Cross-over Study to Evaluate the Effect of Itraconazole and Rifampicin on the Pharmacokinetics (PK) of GSK525762 in Healthy Female Subjects of Non Child Bearing Potential

Neoplasms | Drug Interactions

United States
Addpharma Inc.

Completed

Evaluating the Pharmacokinetic Interactions and Safety Between AD-2111 and AD-2112

Pain

Korea, Republic of
Radboud University Medical Center
Merck Sharp & Dohme LLC

Completed

Pharmacokinetic Study on Raltegravir and Lamotrigine (GRANOLA)

HIV Infection

Netherlands
Pfizer

Completed

Study to Evaluate the Effect of Repeat-Dose Rifampin on the Pharmacokinetics (PK) of PF-06651600

Healthy Volunteers

Belgium
Pfizer

Completed

A STUDY TO EVALUATE THE EFFECT OF PF-06651600 ON PHARMACOKINETICS OF SINGLE DOSE SUMATRIPTAN IN HEALTHY PARTICIPANTS.

Healthy Volunteers

United States
Fundación FLS de Lucha Contra el Sida, las Enfermedades...

Completed

Clinical Trial to Evaluate Pharmacological Interactions Between γ-hydroxybutyrate (GHB) and Cobicistat (GHB_Cobi)

HIV | Pharmacokinetic Interactions

Spain
AstraZeneca
Parexel

Completed

A Study in Healthy Male Subjects to Understand How Savolitinib Behaves Inside the Body (Pharmacokinetics) When Administered Alone and in Combination With Famotidine

Solid Tumours

United States
University of Southern Denmark

Completed

Inter- and Intra-individual Variations in Metformin Pharmacokinetics - The Importance of Genes and Drug Interactions

Metformin | Organic Cation Transporter 1 | Codeine

Denmark
Sihuan Pharmaceutical Holdings Group Ltd.

Unknown

Pharmacokinetic Interactions of Quadruple Therapy With Anaprazole/Amoxicilin/Clarithromycin/Bismuth

Healthy Male Volunteers

3

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