Search clinical trials for: pharmacokinetic modeling

Total 13005 results

Boston Children's Hospital

Not yet recruiting

A Safety and Feasibility Trial Protocol of Metformin in Infants After Perinatal Brain Injury

Hypoxic-Ischemic Encephalopathy | Infant Development | Neurodevelopment | HIE
University Medical Center Groningen

Recruiting

[18F]MC225-PET in Neurodegenerative Disease

Parkinson Disease | Neurodegenerative Diseases | Alzheimer Disease | Mild Cognitive Impairment

Netherlands
University Hospital, Montpellier

Not yet recruiting

Pharmacokinetic Modeling of Methadone (PKMETHAHOME)

Toxicomania
Ain Shams University

Recruiting

PK of SOF/LED in HCV - Infected Adolescents With Haematological Disorders

HCV Infection | Beta Thalassemia Major

Egypt
University Hospital, Rouen

Recruiting

Population Pharmacokinetic Modeling to Optimize the Dosage of the Piperacillin / Tazobactam Combination in Patients With Sepsis in Intensive Care (OPT-TAZ)

Resuscitation Patients With Sepsis

France
University Hospital, Geneva

Completed

Antithrombotics' Therapeutic Optimization in Hospitalized Patients Using Physiologically- and Population-based Pharmacokinetic Modeling (OptimAT)

Cardiovascular Diseases

Switzerland
University of Colorado, Denver

Completed

Effects of Augmented Renal Clearance on Pharmacokinetic and Pharmacodynamic Properties of Levetiracetam in Subarachnoid Hemorrhage

Subarachnoid Hemorrhage

United States
Dent Neuroscience Research Center

Terminated

Central Nervous System Effects Following Infusion of Diphenhydramine Using Pharmacokinetic and Pharmacodynamic Modeling

Central Nervous System Effects of Diphenhydramine | Pharmacokinetics of Diphenhydramine

United States
Ain Shams University
Cairo University

Completed

Pharmacokinetics of Ledipasvir/Sofosbuvir in Hepatitis C Virus-Infected Children With Hematological Malignancy

Hepatitis C, Chronic | Hematologic Malignancy

Egypt
Centre Hospitalier Universitaire de Nīmes

Completed

Personalized Dose Optimization of Amikacin Guided by Pharmacokinetic Modeling Software in Patients With Septic Shock (AMINO BESTDOSE)

Shock, Septic

France
Poznan University of Medical Sciences
University at Buffalo; The Greater Poland Cancer Centre

Active, not recruiting

Translational PKPD Modeling of Anti-infective Drugs Used in Pediatric Units.

Population Modeling of Anti-infective Drugs

Poland
Indiana University

Completed

Pharmacokinetics (PK) and Modeling of Betamethasone Therapy in Threatened Preterm Birth

Premature Labor

United States
Assistance Publique - Hôpitaux de Paris

Completed

Comparison of Two Dosage Adjustment Strategies of Vancomycin in Children (OPTIBAYE)

Methicillin-resistant Staphylococcal Infections

France
Assistance Publique - Hôpitaux de Paris
URC-CIC Paris Descartes Necker Cochin

Completed

Pharmacokinetics of Amiodarone in Children (PK-AMIO)

Heart Rhythm Disorder

France
Assistance Publique - Hôpitaux de Paris
Baxter Healthcare Corporation

Terminated

PK Driven Prophylaxis for Hemophilia A (OBTC)

Hemophilia A

France
Children's Hospital Los Angeles
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Development of Voriconazole Pharmacokinetics and Metabolism in Children and Adolescents

Pharmacokinetics | Voriconazole

United States
Sutep Jaruratanasirikul
Prince of Songkla University

Completed

Pharmacodynamics Modeling to Optimize Dosage Regimens of Sulbactam in Patients With Acinetobacter Infections

Acinetobacter Infections

Thailand
Stanford University
David Drover, MD

Completed

Pharmacokinetic (PK) and Pharmacodynamic (PD) Modeling of Ampicillin and Gentamicin in Peripartum Patients

Drug Metabolism During Pregnancy

United States
University Hospital, Basel, Switzerland

Completed

Physiologically-based Pharmacokinetic Modeling of Ivermectin in Healthy Human Volunteers (IVMPBPK)

Malaria

Switzerland
Rennes University Hospital

Unknown

EC-MOTION : ExtraCorporeal Membrane Oxygenation and Therapeutic Drug Monitoring of Drugs of infectION (EC-MOTION)

Infection

France
Maastricht University Medical Center

Completed

Blood-brain Barrier Quantification in Cerebral Small Vessel Disease

Cerebral Hemorrhage | Cerebral Small Vessel Disease | Blood-Brain Barrier Permeability | Cortical Stroke

Netherlands
Prince of Songkla University

Completed

Population Pharmacokinetics and Pharmacodynamics Modeling to Optimize Dosage Regimen of Levofloxacin

Healthy Volunteers

Thailand
Onze Lieve Vrouw Hospital
University Ghent

Completed

Individualized Cefepime Dosing Study (INCED)

Antimicrobial Treatment
Université de Montréal
Institut de Recherche Robert-Sauvé en Santé et en Sécurité du Travail

Unknown

Impact of Thermal Stress on Pulmonary Absorption and Toxicokinetics of 3 Organic Solvents

Heat

Canada
University of Erlangen-Nürnberg Medical School
German Federal Ministry of Education and Research

Completed

Pain Therapy After Elective Cardiac Surgery (PKPDHM-001)

Pain

Germany
Stanford University

Completed

PK/PD Modeling of Magnesium in the Mother and Neonate

Magnesium Sulfate Pharmacokinetics and Pharmacodynamics

United States
Seoul National University Hospital

Completed

Hematopoietic Stem Cell Transplantation Based on Pharmacokinetic and Pharmacodynamic Modeling

Hematopoietic Stem Cell Transplantation

Korea, Republic of
University of Sao Paulo
Fundação de Amparo à Pesquisa do Estado de São Paulo; Conselho Nacional de...

Completed

Morphine Postoperative Analgesia and Pharmacokinetic/Pharmacodynamic Modeling

Cardiopulmonar Artery Bypass Grafting

Brazil
Uppsala University
University of Copenhagen

Completed

Population Pharmacokinetic-pharmacodynamic (PK-PD) Modeling of Co-administered Gabapentin in Neuropathic Pain

Post-traumatic Neuropathic Pain

Sweden
University of Cologne
University Hospital, Bonn; ZKS Köln

Completed

An Explorative Study on the Pharmacokinetics and Pharmacodynamics of Sunitinib in Healthy Volunteers

Blood Pressure
Cairo University

Not yet recruiting

Effect of Modeling Resin on Anterior Direct Composite Veneer

Dental Decay | Dental Wear
Cascade Pharmaceuticals, Inc

Not yet recruiting

Study to Evaluate Safety, Tolerability and Pharmacokinetics of CS060304 in Healthy and Elevated LDL-C Subjects

MASH

China
Shenzhen Resproly Biopharmaceutical Co., Ltd
Resproly Australia Pty Ltd

Not yet recruiting

A Study to Evaluate Safety, Tolerability and Pharmacokinetics of RSN0402 in Healthy Volunteers

Idiopathic Pulmonary Fibrosis | Lung; Disease, Interstitial, With Fibrosis

Australia
University of Minnesota

Not yet recruiting

A Placebo-controlled, Randomized Clinical Trial to Assess the Safety, Feasibility, and Pharmacokinetics of Microbiota Transplant Therapy With Antibiotic Preconditioning and Fiber Supplementation in Patients With Pulmonary Arterial Hypertension

Pulmonary Arterial Hypertension
DemeRx NB

Not yet recruiting

Multiple Ascending Dose Noribogaine PK/PD in Healthy Volunteers

Pharmacokinetics
National Institute of Allergy and Infectious Diseases...

Recruiting

Modeling Host-Pathogen Interaction Using Lymphoid Organoids

Staphylococcal Infections

United States
Enterprise Therapeutics Ltd

Recruiting

A Two-Part Study to Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of Repeat Doses of Inhaled ETD001 in People With Cystic Fibrosis

Cystic Fibrosis

Germany, France, United Kingdom
Luye Pharma Group Ltd.

Not yet recruiting

Effect of Food on the Pharmacokinetics of LPM3770164 Sustained-release Tablets

Tardive Dyskinesia | Huntington Disease

China
Medibiofarma S.L.

Recruiting

Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of MBF-015 in Huntington's Disease Patients

Huntington Disease

Spain
DSM Nutritional Products, Inc.
Nutrasource Pharmaceutical and Nutraceutical Services, Inc.

Not yet recruiting

A Pharmacokinetic Study of Single Oral Doses of Six Different Vitamin C Product Forms

Healthy | Pharmacokinetic
AstraZeneca

Recruiting

A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of AZD5148 in Healthy Adults

Healthy Participants

United States
Pfizer

Not yet recruiting

A Study to Learn How Different Forms of The Study Medicine Called Phenytoin Are Taken up Into the Blood in Healthy Adults

Healthy
Shivanka Research, LLC
Eric Solutions LLC; Clinexcel Research, Ahmedabad, India

Not yet recruiting

SAD Study to Evaluate Safety, Tolerability, and Pharmacokinetic Profile of KSHN001126 in Healthy Post-Menopausal Females

Healthy Postmenopausal Women

United States, India
Longevity Biotech Australia Pty Ltd (subsidiary)

Not yet recruiting

A Two-Part Single and Multiple Ascending Dose Trial of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of LBT-3627 in Healthy Participants and in Participants With Parkinson's Disease.

Parkinson Disease

Australia
University Hospital, Strasbourg, France

Recruiting

Optimizing the Management of Sickle Cell Patients on Hydroxyurea: The Value of Therapeutic Pharmacological Monitoring (OPTIMDREP)

Sickle Cell Disease

France
MBX Biosciences

Recruiting

Safety, Pharmacokinetics and Efficacy of MBX 2109 in Patients With Hypoparathyroidism

Hypoparathyroidism

United States
Il-Yang Pharm. Co., Ltd.

Not yet recruiting

Clinical Trial to Investigate the Effects of Food on the Pharmacokinetics and Safety of Orally Administered Radotinib

Drug Kinetics

Korea, Republic of
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Analysis of the Influence of Gastric By-Pass on the Pharmacokinetics of Common Drugs (ABSORGYP)

Bypass Bariatric Surgery

France
Zhejiang Sunshine Mandi Pharmaceutical Co.,Ltd.

Not yet recruiting

Pharmacokinetics, Safety and Tolerability of Clascoterone Cream 1% in Healthy Chinese Adult Subjects

Acne Vulgaris
Universität des Saarlandes

Recruiting

Pharmacokinetics of Bisoprolol and SGLT2i in Acutely Decompensated Heart Failure (BISO-ADHF)

Acute Decompensated Heart Failure

Germany

Search clinical trials for: pharmacokinetic modeling

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