Search clinical trials for: preoperative radiotherapy and local excision

Total 472213 results

Stanford University

Recruiting

Surgical Excision vs Neoadjuvant Radiotherapy+Delayed Surgical Excision of Ductal Carcinoma (NORDIS)

Ductal Breast Carcinoma in Situ

United States
CNAO National Center of Oncological Hadrontherapy
Foundation IRCCS San Matteo Hospital

Recruiting

Carbon Ions Radiation Therapy for Resectable or Borderline Resectable Pancreas Adenocarcinoma (PIOPPO)

Pancreas Adenocarcinoma | Resectable Pancreatic Cancer | Cancer of Pancreas

Italy
NRG Oncology
National Cancer Institute (NCI)

Recruiting

Comparing Proton Therapy to Photon Radiation Therapy for Esophageal Cancer

Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8 | Postneoadjuvant Therapy Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8 | Postneoadjuvant Therapy Stage IIIA Gastroesophageal Junction Adenocarcinoma AJCC v8 | Postneoadjuvant Therapy Stage IIIB Gastroesophageal... and other conditions

United States
Yonsei University

Not yet recruiting

Evaluation of Efficacy, Quality of Life and Cost Effectiveness of Short-course Radiotherapy Followed by Capecitabine Plus Oxaliplatin chemotheRapy and TME for High-risk Rectal Cancer (ESCORT Trial)

Locally Advanced Rectal Cancer

Korea, Republic of
Sixth Affiliated Hospital, Sun Yat-sen University

Recruiting

Total Mesorectal Excision(TME) With Lateral Lymph Node Dissection Versus TME After Neoadjuvant Chemo-radiotherapy (TELEPHOME)

Rectal Neoplasm Malignant

China
Azienda Ospedaliero-Universitaria Careggi

Recruiting

Radiotherapy in Preoperative Setting With CyberKnife for Breast Cancer (ROCK)

Early Breast Cancer

Italy
University of Birmingham

Recruiting

Can we Save the Rectum by Watchful Waiting or TransAnal Surgery Following (Chemo)Radiotherapy Versus Total Mesorectal Excision for Early REctal Cancer? (STAR-TREC)

Adenocarcinoma of the Rectum

Denmark, Netherlands, United Kingdom, Belgium, Sweden
Tata Memorial Hospital

Recruiting

Perioperative Therapy Preoperative Chemotherapy Versus Chemoradiotherapy in Locally Advanced Gall Bladder Cancers (POLCAGB)

Gall Bladder Cancers

India
Medical University of Vienna

Recruiting

p53 and Response to Preoperative Radiotherapy for T2 and T3 (PART1)

Rectal Cancer

Austria
Dr. Gordon Buduhan
University of Toronto; London Health Sciences Centre; CancerCare Manitoba

Recruiting

Preoperative Chemotherapy vs. Chemoradiation in Esophageal / GEJ Adenocarcinoma (POWERRANGER)

Esophageal Cancer | Adenocarcinoma, Esophageal | Adenocarcinoma, Gastroesophageal Junction

Canada
National Cancer Institute (NCI)

Suspended

Testing Nivolumab and Ipilimumab With Short-Course Radiation in Locally Advanced Rectal Cancer

Stage III Rectal Cancer AJCC v8 | Locally Advanced Rectal Adenocarcinoma | Stage II Rectal Cancer AJCC v8

United States
National Cancer Institute (NCI)

Active, not recruiting

Atezolizumab, Pemetrexed Disodium, Cisplatin, and Surgery With or Without Radiation Therapy in Treating Patients With Stage I-III Pleural Malignant Mesothelioma

Biphasic Mesothelioma | Epithelioid Mesothelioma | Stage III Pleural Malignant Mesothelioma AJCC v7 | Stage I Pleural Malignant Mesothelioma AJCC v7 | Stage IA Pleural Malignant Mesothelioma AJCC v7 | Stage IB Pleural Malignant Mesothelioma AJCC v7 | Stage II Pleural Malignant Mesothelioma AJCC...

United States
Hoffmann-La Roche
NSABP Foundation Inc; German Breast Group

Active, not recruiting

A Study of Trastuzumab Emtansine Versus Trastuzumab as Adjuvant Therapy in Patients With HER2-Positive Breast Cancer Who Have Residual Tumor in the Breast or Axillary Lymph Nodes Following Preoperative Therapy (KATHERINE)

Breast Cancer

United States, Italy, United Kingdom, Canada, Czechia, Argentina, Austria, Belgium, Brazil, China, France, Germany, Guatemala, Ireland, Panama, Spain, Sweden, Taiwan, Turkey, Colombia, Hong Kong, Peru, Switzerland, South Africa, Israel, G... and more
Sun Yat-sen University

Active, not recruiting

PD1 Antibody Toripalimab and Chemoradiotherapy for dMMR/MSI-H Locally Advanced Colorectal Cancer

DMMR Colorectal Cancer | MSI-H Colorectal Cancer | Locally Advanced Colorectal Cancer

China
Johns Hopkins University

Withdrawn

Preoperative Image-based Education Effect on Postoperative Satisfaction of Patients Undergoing First-time Dermatologic Surgery

Skin Cancer | Skin Wound
Sir Run Run Shaw Hospital

Active, not recruiting

Preoperative Short-course Radiation Followed by Envafolimab Plus CAPEOX for MSS Locally Advanced Rectal Adenocarcinoma (PRECAM)

MSS Locally Advanced Rectal Adenocarcinoma

China
Swiss Group for Clinical Cancer Research

Completed

Preoperative Chemoradiotherapy vs. Chemotherapy Alone in NSCLC Patients

Lung Cancer

Germany, Serbia, Switzerland
Memorial Sloan Kettering Cancer Center
University of Colorado, Denver; Washington University School of Medicine; University... and other collaborators

Active, not recruiting

Trial Evaluating 3-year Disease Free Survival in Patients With Locally Advanced Rectal Cancer Treated With Chemoradiation Plus Induction or Consolidation Chemotherapy and Total Mesorectal Excision or Non-operative Management

Rectal Cancer

United States
Prof. Dr. med. Claus Rödel
Johann Wolfgang Goethe University Hospital; Deutsche Krebshilfe e.V., Bonn...

Completed

Induction Chemotherapy Before or After Preoperative Chemoradiotherapy and Surgery for Locally Advanced Rectal Cancer (CAOAROAIO-12)

Rectal Neoplasms | Rectal Cancer Stage II | Rectal Cancer Stage III

Germany
NRG Oncology
National Cancer Institute (NCI)

Terminated

Testing the Addition of Targeted Radiation Therapy to Surgery and the Usual Chemotherapy Treatment (Pemetrexed and Cisplatin [or Carboplatin]) for Stage I-IIIA Malignant Pleural Mesothelioma

Pleural Biphasic Mesothelioma | Pleural Epithelioid Mesothelioma | Stage I Pleural Malignant Mesothelioma AJCC v8 | Stage IA Pleural Malignant Mesothelioma AJCC v8 | Stage IB Pleural Malignant Mesothelioma AJCC v8 | Stage II Pleural Malignant Mesothelioma AJCC v8 | Stage IIIA Pleural Malignant...

United States, Canada
Duke University

Completed

Single Dose Partial Breast Radiotherapy (RSU)

Breast Cancer

United States
Duke University
Gateway for Cancer Research

Active, not recruiting

Preoperative Single-Fraction Radiotherapy in Early Stage Breast Cancer

Breast Cancer

United States
Karolinska Institutet
Swedish Cancer Society

Completed

Sexual Function and Wellbeing in Males With Rectal Cancer

Rectal Cancer

Sweden
Institut du Cancer de Montpellier - Val d'Aurelle

Completed

Sphincter-preserving Surgery After Preoperative Treatment of Ultra-low Rectal Carcinoma (GRECCAR1)

Rectal Cancer

France
Istituto Scientifico Romagnolo per lo Studio e...

Completed

Phase II Study of Up-front Chemotherapy and Neo-adjuvant Short-course Radiotherapy for Resectable Rectal Carcinoma (COLORE) (COLORE)

Rectal Carcinoma

Italy
University of Alabama at Birmingham
Aventis Pharmaceuticals; Pharmacia and Upjohn

Completed

Irinotecan and Taxotere With Radiotherapy as Preoperative Treatment in Resectable Esophageal Cancer

Esophageal Cancer | Cancer of the Esophagus | Esophageal Neoplasm | Esophagus Cancer | Cancer of Esophagus

United States
Sun Yat-sen University
The First Affiliated Hospital with Nanjing Medical University; Zhejiang Cancer... and other collaborators

Active, not recruiting

CONVERT: Neoadjuvant Chemotherapy Alone Versus Preoperative Chemoradiation for Locally Advanced Rectal Cancer Patients

Rectal Neoplasms

China
H. Lee Moffitt Cancer Center and Research Institute

Terminated

Preoperative Stereotactic Ablative Body Radiotherapy (SABR) for Early-Stage Breast Cancer

Breast Cancer | Breast Cancer Female | Breast Adenocarcinoma

United States
Jagiellonian University

Completed

Randomized Clinical Trial on Preoperative Radiotherapy 25 Gy in Rectal Cancer

Rectal Cancer

Poland
Southwest Oncology Group
National Cancer Institute (NCI)

Completed

S1505: Combination Chemotherapy or Gemcitabine Hydrochloride and Paclitaxel Albumin-Stabilized Nanoparticle Formulation Before Surgery in Treating Patients With Pancreatic Cancer That Can Be Removed by Surgery

Pancreatic Adenocarcinoma | Resectable Pancreatic Carcinoma

United States
Andre Nazac

Completed

Feasibility Study of Accelerated Preoperative Radiotherapy for Early Breast Cancer

Breast Cancer

Belgium
Lawson Health Research Institute

Withdrawn

SIGNAL During a COVID-19 Pandemic

Breast Cancer
Istanbul Breast Society

Completed

Efficacy of Preoperative Radiotherapy for Non-responder Patients After Neoadjuvant Chemotherapy

Breast Cancer | Breast Neoplasms | Survivorship | Radiotherapy; Complications

Turkey
Hebei Medical University

Completed

Preoperative Concurrent Chemoradiotherapy for Potentially Resectable Adenocarcinoma of the Esophagogastric Junction (A-C)

Gastroesophageal Junction Adenocarcinoma

China
Corporacion Parc Tauli
Fundación Olga Torres

Completed

Preoperative Chemoradiotherapy and Transanal Endoscopic Microsurgery Versus Total Mesorectal Excision in T2-T3s N0, M0 Rectal Cancer

Rectal Cancer

Spain
Adlai Nortye Biopharma Co., Ltd.

Completed

Preoperative Radiotherapy and E7046 in Rectum Cancer (PRAER 1)

Neoadjuvant Therapy in Rectal Cancer

United States, United Kingdom, Poland
Cancer Institute and Hospital, Chinese Academy...

Completed

Preoperative Chemoradiotherapy With Raltitrexed for Intermediate or Locally Advanced Rectal Cancer in the Fit Elderly

Rectal Neoplasms Malignant

China
Pere Planellas Giné

Completed

Preoperative Prediction Model of Pathological Outcomes (Mesorectum Quality and Positive Circumferential Resection Margin) in Patients With Mid-low Rectal Cancer (PREMARE)

Rectal Cancer

Spain
Peking University Cancer Hospital & Institute

Completed

Total Neoadjuvant Induction and Consolidation CapeOX Plus IMRT With Capecitabine for MRI Defined High-risk Rectal Cancer

Rectal Cancer

China
Peking University Cancer Hospital & Institute

Completed

Tailored Operative or Non-operative Management for Low-risk Rectal Cancer After Intensive Neoadjuvant Treatment

Rectal Cancer

China
Yonsei Hyperthermia Study Group

Active, not recruiting

The Effect of Electro-Hyperthermia in Preoperative Radiotherapy for Locally Advanced Rectal Cancer

Hyperthermia | Rectal Cancer

Korea, Republic of
Karolinska Institutet
Swedish Cancer Society

Completed

Sexual Function and Wellbeing in Females With Rectal Cancer

Rectal Cancer

Sweden
UMC Utrecht

Withdrawn

MRI-guided Single Dose Preoperative Radiotherapy in Low-risk Breast Cancer (ABLATIVE-2)

Breast Cancer

Netherlands
Blokhin's Russian Cancer Research Center

Enrolling by invitation

Neoadjuvant Chemotherapy in Patients With Intermediate Risk Upper and Mid Rectal Cancer (RuCorT-01)

Rectal Cancer | Rectum Carcinoma | Rectal Neoplasms Malignant

Russian Federation
Asan Medical Center

Completed

Preoperative CRT With Temozolomide Plus Capecitabine in Rectal Cancer

Rectal Cancer

Korea, Republic of
National Cancer Institute, Naples

Completed

Bevacizumab With Pelvic Radiotherapy And Primary Chemotherapy in Patients With Poor-Risk Rectal Cancer (BRANCH)

Rectal Cancer
Universitair Ziekenhuis Brussel
Vrije Universiteit Brussel

Completed

Simultaneous Integrated Boost Preoperative Radiotherapy for Rectum Cancer (RectumSIB)

Rectal Cancer

Belgium
Wuhan Union Hospital, China

Active, not recruiting

Preoperative Short Course Radiotherapy With Chemotherapy and Camerelizumab in Locally Advanced Rectal Cancer

Rectal Cancer | Radiotherapy | Immunotherapy

China
Austrian Breast & Colorectal Cancer Study Group
Hoffmann-La Roche

Terminated

Preoperative Combined RadioChemo-Molecular Target Therapy With Capecitabine, Bevacizumab, and Radiotherapy

Rectal Cancer

Austria
Peking University Cancer Hospital & Institute

Unknown

Total Neoadjuvant Treatment Plus SHR1210 for High-risk Rectal Cancer and Biomarker Screening Base on Neoantigen

Rectal Cancer

China

Search clinical trials for: preoperative radiotherapy and local excision

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