Search clinical trials for: prophylactic treatment

Total 63979 results

St. Olavs Hospital
Ullevaal University Hospital; Oslo University Hospital; University Hospital of... and other collaborators

Not yet recruiting

Prophylactic Treatment With Atorvastatin for Episodic Migraine. (EStatinMig)

Episodic Migraine
Yonsei University

Not yet recruiting

Clinical Trial for Non-inferiority and Safety of Tenofovir Alafenamide and Tenofovir Disoproxil Fumarate in Patients With Hematologic Malignancies Who Require Prophylactic Hepatitis B Antiviral Treatment

Patients With Malignant Blood Disease Requiring Hepatitis B Antiviral Medication
Loewenstein Hospital

Recruiting

Prophylactic Pregabalin Treatment Following Spinal Cord Injury

Spinal Cord Diseases | Spinal Cord Injuries

Israel
Centre Hospitalier Régional Metz-Thionville

Recruiting

Real-life Study of the Efficacy of Management of Migraine Patients After Failure of 2 Prophylactic Treatments (EVIREMIG)

Migraine

France
Children's Hospital of Fudan University

Recruiting

Preventive Effect of Prophylactic Oral Antibiotics Against Cholangitis After Kasai Portoenterostomy

Cholangitis | Anti-Bacterial Agents | Biliary Atresia

China
Chongqing University Cancer Hospital

Recruiting

Early Intervention to Prevent Lower Limb Lymphedema of Gynecological Malignancy

Uterine Cervical Neoplasms | Lymphedema | Endometrial Neoplasms | Treatment Effectiveness

China
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Prophylactic Frequent Premature Ventricular complexeS sUPPression on Left ventriculaR Function impairmEnt in aSymptomatic patientS (SUPPRESS)

Ventricular Dysfunction, Left | Premature Ventricular Contractions
AHS Cancer Control Alberta

Not yet recruiting

Prophylactic Mesalamine to Prevent Colitis Following Treatment With Ipilimumab/Nivolumab (Ipi/Nivo) (IMPACT 1)

Diarrhea | Advanced Melanoma | Immune-related Adverse Event | Advanced Rectal Carcinoma

Canada
Shanghai 10th People's Hospital

Recruiting

Safety and Efficacy of Prophylactic Arterial Embolization in the Treatment of Angiography-negative Acute Upper Gastrointestinal Bleeding

Acute Gastrointestinal Bleeding

China
The First Affiliated Hospital of Dalian Medical...
Cancer Institute and Hospital, Chinese Academy of Medical Sciences; Chinese... and other collaborators

Recruiting

Efficacy and Safety of rhTPO's Prophylactic Treatment of CTIT in Patients With High Risk of Cardiac Injury (Circular)

Cancer Treatment Induced Thrombocytopenia

China
Ionis Pharmaceuticals, Inc.

Recruiting

A Study to Assess the Long-Term Safety and Efficacy of Donidalorsen in the Prophylactic Treatment of Hereditary Angioedema (HAE)

Hereditary Angioedema

United States, Puerto Rico, Belgium, Bulgaria, Canada, France, Germany, Israel, Italy, Netherlands, Poland, Spain, Turkey, United Kingdom
Gerhild Becker

Recruiting

Protreat-Trial: Prophylactic Antiemetic Treatment of Opioid-induced Nausea and Vomiting (OINV) in Palliative Care (ProTreat)

Pain | Nausea | Vomiting | Advanced Cancer

Germany
Zealand University Hospital

Recruiting

Prophylactic Antibiotic Treatment in Hemodialysis (PANTHEM)

Hemodialysis

Denmark
Peking University First Hospital

Recruiting

The Efficacy and Safety of 12-week SOF/VEL Regimen Combined With Prophylactic Use of TAF for Treatment-naïve Genotype 1-6 HCV/HBV Co-infection Adult Patients With or Without Compensated Cirrhosis in China (BDTAF)

Chronic Hepatitis B | Chronic Hepatitis C

China
Odense University Hospital

Recruiting

Bacterial Interference for Preventing Recurrent Urinary Tract Infection - New Ways of Treatment (BIrUTI)

Recurrent Urinary Tract Infections

Denmark
European Organisation for Research and Treatment...
UNICANCER

Recruiting

PRophylactic Cerebral Irradiation or Active MAgnetic Resonance Imaging Surveillance in Small-cell Lung Cancer Patients (PRIMALung Study) (PRIMALung)

Extensive-stage Small-cell Lung Cancer | Limited Stage Small Cell Lung Cancer

United Kingdom, Belgium, Switzerland, Italy, France, Germany, Poland, Spain, Austria
American Thrombosis and Hemostasis Network
LFB USA, Inc.

Recruiting

SEVENFACT® for Bleeding Events in Hemophilia With Inhibitors

Hemophilia A With Inhibitor | Hemophilia B With Inhibitor

United States
Merck Sharp & Dohme LLC

Recruiting

Placebo-controlled, Study of Concurrent Chemoradiation Therapy With Pembrolizumab Followed by Pembrolizumab and Olaparib in Newly Diagnosed Treatment-Naïve Limited-Stage Small Cell Lung Cancer (LS-SCLC) (MK 7339-013/KEYLYNK-013)

Small Cell Lung Cancer

United States, Australia, Belgium, Bulgaria, Canada, China, France, Greece, Hungary, Israel, Italy, Japan, Korea, Republic of, Lithuania, Mexico, Portugal, Romania, Russian Federation, Serbia, South Africa, Spain, Turkey, Ukraine, United... and more
SWOG Cancer Research Network
National Cancer Institute (NCI)

Recruiting

S1827 (MAVERICK) Testing Whether the Use of Brain Scans Alone Instead of Brain Scans Plus Preventive Brain Radiation Affects Lifespan in Patients With Small Cell Lung Cancer

Extensive Stage Lung Small Cell Carcinoma | Limited Stage Lung Small Cell Carcinoma | Lung Small Cell Carcinoma

United States, Canada, Korea, Republic of, Mexico
University of Calgary

Not yet recruiting

Cannabis for the Prophylactic Treatment of Migraine

Chronic Migraine
Instituto Nacional de Cancerologia de Mexico
Instituto Nacional de Enfermedades Respiratorias

Recruiting

Prophylactic Inhaled Steroids to Reduce Radiation Pneumonitis Frequency and Severity in Lung Cancer Patients

Radiation Pneumonitis

Mexico
Peng Zhang

Recruiting

Neoadjuvant Therapy Combined With Radical Surgery for the Treatment of Small Cell Lung Cancer (SCLC) in II and IIIA Stage

Small-cell Lung Cancer

China
Centre Hospitalier Universitaire de Nīmes

Recruiting

Shared Medical Decision Making in the Prophylactic Treatment of Bipolar Disorder (ShareD-BD)

Bipolar Disorder

France
Institute of Cancer Research, United Kingdom
National Cancer Institute (NCI); ECOG-ACRIN Cancer Research Group

Recruiting

International Penile Advanced Cancer Trial (International Rare Cancers Initiative Study) (InPACT)

Squamous Cell Carcinoma of the Penis, Usual Type

United States, United Kingdom
Assaf-Harofeh Medical Center
Rambam Health Care Campus; Rabin Medical Center; Tel-Aviv Sourasky Medical Center and other collaborators

Recruiting

Prophylactic Irradiation to the Contralateral Breast for BRCA Mutation Carriers Undergoing Treatment for Breast Cancer

Breast Cancer

Israel
Bayer

Active, not recruiting

Study to Evaluate the Efficacy (Effect on Disease) and Safety of Finerenone on Morbidity (Events Indicating Disease Worsening) & Mortality (Death Rate) in Participants With Heart Failure and Left Ventricular Ejection Fraction (Proportion of Blood Expelled Per Heart Stroke) Greater or Equal to 40% (FINEARTS-HF)

Heart Failure

United States, Spain, Denmark, Korea, Republic of, Taiwan, Australia, Hong Kong, Russian Federation, Israel, Canada, Malaysia, United Kingdom, Latvia, Netherlands, Japan, Brazil, China, Lithuania, Poland, Turkey, Italy, Austria, Bul... and more
CHRISTUS Health

Completed

Efficacy of Prophylactic Treatment of Oral Prochlorperazine for Acute Mountain Sickness (PAMS)

Acute Mountain Sickness | AMS

United States
SWOG Cancer Research Network
National Cancer Institute (NCI)

Terminated

Prophylactic Antiviral Therapy in Patients With Current or Past Hepatitis B Virus Infection Receiving Anti-Cancer Therapy for Solid Tumors

Malignant Solid Neoplasm | Hepatitis B Infection

United States, Guam
CSL Behring

Active, not recruiting

Long-term Safety and Efficacy of CSL312 (Garadacimab) in the Prophylactic Treatment of Hereditary Angioedema Attacks

Hereditary Angioedema

Australia, Canada, United States, New Zealand, Germany, Hong Kong, Netherlands, Taiwan, Czechia, Israel, Hungary, Japan, Russian Federation, Spain
Dompé Farmaceutici S.p.A

Completed

Clinical Trial of Efficacy and Safety of Levopront® 30 mg/5 ml in Patients With Dry Cough (LDP0114)

Cough

Russian Federation
Institut National de la Santé Et de la Recherche...
UPCET; PARTNERS for International clinical Research; European Fundation for the... and other collaborators

Active, not recruiting

Prophylactic Treatment of the Ductus Arteriosus in Preterm Infants by Acetaminophen (TREOCAPA)

Acetaminophen | Patency of the Ductus Arteriosus | Extreme Prematurity

France, Norway, Belgium, Estonia, Ireland, Switzerland, Sweden, Denmark, Finland, Hungary, Italy, Portugal
Helsinn Healthcare SA
Chiltern International Inc.

Completed

Dose Finding Study in Colorectal Cancer Patients Receiving 5-FU-based Chemotherapy to Assess the Efficacy of Elsiglutide in the Prevention of Chemotherapy Induced Diarrhea (CID)

Drug and/or Toxin-induced Diarrhea

Ukraine, Germany, Poland, Russian Federation, Belarus, Bulgaria, Hungary, Czechia
Merck Sharp & Dohme LLC

Active, not recruiting

A Study of Doravirine/Islatravir (DOR/ISL, MK-8591A) for the Treatment of Human Immunodeficiency Virus 1 (HIV-1) Infection in Participants Who Previously Received DOR/ISL (MK-8591A-054)

HIV Infection

United States, Russian Federation, Argentina, Australia, Canada, Chile, Colombia, Israel, Japan, New Zealand, Puerto Rico, South Africa, Switzerland, Taiwan, United Kingdom
Merck Sharp & Dohme LLC

Completed

Doravirine/Islatravir (DOR/ISL) in Heavily Treatment-Experienced (HTE) Participants for Human Immunodeficiency Virus Type 1 (HIV-1) Infection (MK-8591A-019)

HIV-1 Infection

United States, Australia, Canada, Chile, Colombia, France, Germany, Italy, Japan, Korea, Republic of, Peru, Portugal, Puerto Rico, Russian Federation, South Africa, Spain, Ukraine, United Kingdom
KalVista Pharmaceuticals, Ltd.

Terminated

A Trial to Evaluate the Efficacy and Safety of Different Doses of KVD824 for Prophylactic Treatment of HAE Type I or II (KVD824-201)

Angioedema, Hereditary, Types I and II

United States, Czechia, Germany, Hungary, Italy, North Macedonia, United Kingdom, Australia, Bulgaria, Canada, France, New Zealand, Puerto Rico
Allergan

Completed

Atogepant for Prophylaxis of Migraine in Participants Who Failed Previous Oral Prophylactic Treatments. (ELEVATE)

Episodic Migraine

United States, Australia, Canada, Czechia, Denmark, France, Germany, Hungary, Italy, Netherlands, Poland, Russian Federation, Spain, Sweden, United Kingdom
Takeda

Completed

A Study of Standard and Individualized Prophylactic Treatment With Advate in Men and Boys With Severe Hemophilia A (HAPKIDO)

Hemophilia A

Russian Federation
Groupe Oncologie Radiotherapie Tete et Cou
UNICANCER; Center Eugene Marquis

Active, not recruiting

Trial Evaluating the Tolerance and Safety of Durvalumab - RT Combination for Treatment in SCCHN (REWRITe)

HNSCC

France
Campus Bio-Medico University

Completed

Cyclosporine 0.1% Eye Drops as Prophylactic Treatment In Cataract Surgery (CSA2020)

Ocular Inflammation | Ocular Surface Disease

Italy
Dong-Gun Lee

Enrolling by invitation

Prophylactic Entecavir for HBV Reactivation in Past HBV Infected Patients With Hematopoietic Stem Cell Transplantation

HBV | Hematopoietic Stem Cell Transplantation | Hepatitis B Reactivation | Antiviral Drug

Korea, Republic of
Memo Therapeutics AG

Completed

To Assess the Safety and Tolerability of MTx-COVAB36 as a Therapeutic and Prophylactic Treatment Against COVID-19.

SARS-CoV-2 Infection

Australia
Amgen

Completed

Phase 3 Study With Carfilzomib and Dexamethasone Versus Bortezomib and Dexamethasone for Relapsed Multiple Myeloma Patients (ENDEAVOR)

Multiple Myeloma

Korea, Republic of, Spain, Taiwan, Canada, Australia, Israel, Italy, United States, Singapore, New Zealand, Japan, Thailand, Brazil, United Kingdom, Hungary, Czechia, Romania, Slovakia, France, Germany, Russian Federation, Bulgaria, Belgiu... and more
Prof. Dr. Richard F Schlenk

Terminated

Quizartinib and High-dose Ara-C Plus Mitoxantrone in Relapsed/Refractory AML With FLT3-ITD (Q-HAM)

AML According to WHO 2016 Classification (Except Acute Promyelocytic Leukemia) AND (Refractory to Induction Therapy OR Relapsed After First Line Treatment)

Germany
Marinomed Biotech AG

Completed

Prophylactic Treatment With Carragelose Nasal Spary to Prevent SARS-CoV-2, COVID-19, Infections in Health Care Workers

COVID-19 | Common Cold | Respiratory Viral Infection | Severe Acute Respiratory Syndrome (SARS) Pneumonia | Corona Virus Disease

Austria
Gitte Moos Knudsen

Terminated

Prophylactic Effects of Psilocybin on Chronic Cluster Headache (EPOCH)

Cluster Headache

Denmark
Daiichi Sankyo, Inc.

Completed

Edoxaban for Prevention of Blood Vessels Being Blocked by Clots (Thrombotic Events) in Children at Risk Because of Cardiac Disease

Cardiac Disease

United States, Spain, Canada, Lebanon, Turkey, Austria, Croatia, Egypt, France, Hungary, India, Israel, Ukraine, United Kingdom
Carolina Eyecare Physicians, LLC
Science in Vision; Imprimis Pharmaceuticals, Inc.

Completed

Prophylactic Treatment: Lessdrops™ vs Standard Drops Regimen

Cataract

United States
TWi Biotechnology, Inc.

Completed

Prophylactic Treatment of Skin Rash Associated With EGFR Inhibitor Therapy

EGFR Inhibitor-Induced Skin Rash

Taiwan
Prof. Dr. Matthias Preusser

Completed

A Single-blinded, Randomized, Placebo Controlled Phase II Trial of Prophylactic Treatment With Oral Azithromycin Versus Placebo in Cancer Patients Undergoing Antineoplastic Treatment During the Corona Virus Disease 19 (COVID-19) Pandemic

COVID

Austria
Göteborg University

Terminated

Saline Injections for Prophylactic Treatment of Chronic Migraine

Chronic Migraine

Sweden

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