Search clinical trials for: randomised double blind crossover trial

Total 46845 results

Woolcock Institute of Medical Research
University of Sydney

Completed

Cannabinol Use in Patients With Insomnia Disorder (CUPID)

Insomnia Disorder

Australia
Imperial College London
Foundation for Circulatory Health

Completed

The Effect of Nebivolol on Insulin Sensitivity

Hypertension

United Kingdom
Adocia

Completed

A Double-blinded, Randomised, Two -Period Crossover Euglycemic Clamp Trial Investigating the Pharmacokinetics, Glucodynamics and Safety of BioChaperone Insulin Lispro and Insulin Lispro (Humalog®) in Subjects With Type 1 Diabetes

Diabetes Mellitus Type 1

Germany
Adocia

Completed

A Double-blinded, Randomised, Three-period Crossover Euglycaemic Clamp Trial Investigating the Pharmacokinetics, Glucodynamics and Safety of BioChaperone Human Insulin, Human Insulin (Huminsulin® Normal) and Insulin Lispro (Humalog®) in Subjects With Type 1 Diabetes

Diabetes Mellitus Type 1

Germany
Adocia

Completed

A Double-blinded, Randomised, Four-period Crossover Euglycemic Clamp Trial Investigating the Dose-response and Dose-exposure Relationship of BioChaperone Insulin Lispro in Three Different Doses in Subjects With Type 1 Diabetes

Diabetes Mellitus Type 1

Germany
University of Aarhus
Spirare ApS

Completed

Efficacy and Safety of Nasal Filters on Seasonal Allergic Rhinitis (Hay Fever)

Rhinitis, Allergic, Seasonal

Denmark
Medical University of Graz

Completed

A Randomised, Single Centre, Double-Blind, Two-Period Crossover, Glucose Clamp Trial (ENM-HS-001)

Diabetes, Type I

Austria
Azienda Ospedaliera Universitaria Policlinico "G...

Recruiting

Randomised Double-blind Active vs. Placebo Clinical Trial on the Effect of a Food Supplement on IBS-D in Children

Irritable Bowel Syndrome With Diarrhea

Italy
Yanbing Li

Not yet recruiting

Efficacy and Safety of Chiglitazar Added to Glargine in Patients With Type 2 Diabetes

Efficacy and Safety of Chiglitazar Sodium in the Treatment of T2DM Patients | Metformin Combined With Insulin Glargine in the Treatment of Type 2 Diabetes Patients Who Still Have Poor Hypoglycemic Effect | 128 Patients Were Randomly Assigned 1:1 | Metformin and Insulin Glargine Combined... and other conditions

China
The Florey Institute of Neuroscience and Mental...
The University of Queensland; Mobius Medical Pty Ltd.

Recruiting

A Double-blind Randomised, Placebo-controlled Clinical Trial to Test Ambroxol Treatment in ALS (AMBALS)

Amyotrophic Lateral Sclerosis

Australia
COMPASS Pathways

Recruiting

A Phase II, Multicentre, Randomised, Double-blind, Controlled Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Efficacy of COMP360 in Participants With Recurrent Major Depressive Disorder

Major Depressive Disorder

United States
Godavari Biorefineries Limited

Not yet recruiting

Phase One Clinical Trial to Assess the Safety, Tolerability and Pharmacokinetics of MSP008-22 in Healthy Adult Volunteers

COVID-19

India
Cambridge University Hospitals NHS Foundation Trust
University of Cambridge

Recruiting

CCMR Two: A Phase IIa, Randomised, Double-blind, Placebo-controlled Trial of the Ability of the Combination of Metformin and Clemastine to Promote Remyelination in People With Relapsing-remitting Multiple Sclerosis Already on Disease-modifying Therapy

Multiple Sclerosis

United Kingdom
Wuerzburg University Hospital

Recruiting

Dystonia Image-based Programming of Stimulation: A Prospective, Randomized, Double-blind Crossover Trial (DIPS)

Dystonia | Deep Brain Stimulation

Germany
Federal University of Paraíba

Recruiting

Effects of Dualsite Anodic tDCS on Lower Limbs Function in Patients After Stroke: Randomized, Double-blind, Placebo-controlled, Crossover Trial

Stroke, Chronic

Brazil
Professor Robert Sutton
Merck Sharp & Dohme LLC; Medical Research Council; Liverpool University Hospitals... and other collaborators

Recruiting

Randomised Treatment of Acute Pancreatitis With Infliximab: Double-blind Multi-centre Trial (RAPID-I) (RAPID-I)

Acute Pancreatitis

United Kingdom
University Hospital, Clermont-Ferrand
Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement and other collaborators

Terminated

GlutN : Randomized, Double-blind, Crossover Clinical Trial to Confirm the Role of Gluten in Non-celiac Gluten Sensitivity (GLUTN)

The Objective is to Confirm the Role of Gluten in Triggering the Digestive and Extradigestive Symptoms of NCGS

France
Geistlich Pharma AG

Withdrawn

AMIC vs. MFx in the Ankle (AMARTA)

Chondral Defect | Osteochondral Lesion of Talus | Microfracture

United Kingdom
Igy Inc.
Vetanda Group Ltd

Completed

A Randomized, Double-Blind, Placebo Controlled, Crossover Trial to Evaluate Safety and Efficacy of AGY in Celiac Disease (AGY-010)

Celiac Disease

Canada
Oulu University Hospital

Completed

LTAP Block in Endometriosis Surgery - a Randomised Controlled Double-blind Trial

Postoperative Pain | Endometriosis; Peritoneum

Finland
Boehringer Ingelheim

Completed

A Prospective, Randomised, Double-blind, Double-dummy, Forced-titration, Multicentre, Parallel Group, One Year Treatment Trial to Compare Telmisartan (MICARDIS) 80 mg Versus Losartan (COZAAR) 100 mg, in Hypertensive Type 2 Diabetic Patients With Overt Nephropathy (AMADEO Study)

Hypertension | Diabetic Nephropathies

Taiwan, United States, Canada, Thailand, Korea, Republic of, Argentina, Australia, Brazil, Mexico, New Zealand
Universidad de Almeria

Completed

Efficacy of Therapy Using Monopolar Dielectric Radiofrequency Signals on the Symptoms of Myofascial Trigger Points in Patients With Chronic Nonspecific Low Back Pain.

Chronic Pain

Spain
GiMer Medical

Completed

A Prospective, Multi-site, Randomized, Sham-Controlled, Double-Blind Trial With One-Way Crossover Designed to Assess the Effectiveness and Safety of the Gimer NeuroBlock SCS Trialing System for the Treatment of Chronic Back Pain and/or Lower Limb Pain

Low Back Pain | Chronic Pain | Lower Limb Pain

Taiwan
Globe Biotech Limited

Completed

A Randomized, Double-blinded, Active Controlled Crossover Clinical Trial to Investigate PK, PD and Safety of GBPD002

Natural Blood and Blood Product Toxicity

Bangladesh
Shandong University
Fudan University; Chinese Nutrition Society

Completed

SREBF1 Polymorphism and Egg Yolk on Cardiovascular Disease Risk in Healthy Young Adults: a Randomised, Two-period, Single Blinded, Crossover Trial

Healthy | GEN1 Gene Mutation

China
AstraZeneca
Parexel

Completed

A Study to Assess the Effect of Verinurad on the Electric Activity of the Heart

Healthy Volunteers (Intended Indication: Chronic Kidney Disease)

Germany
Nutricia Research

Active, not recruiting

Renoir: A Randomised, Double-blind, Controlled Trial to Evaluate the Effects of a New Human Milk Fortifier on Growth and Tolerance in Preterm Infants. (Renoir)

Growth | Tolerance | Safety | Subjects in Need of a Human Milk Fortifier (HMF)

Netherlands, France, Germany, United Kingdom
The University of Queensland
Telethon Kids Institute

Completed

Prevention of Bronchiectasis in Infants With Cystic Fibrosis (COMBATCF)

Bronchiectasis | Cystic Fibrosis

Australia, New Zealand
Maimónides Biomedical Research Institute of Córdoba

Completed

Crossover Clinical Trial, Randomized, Double Blind, Placebo Controlled Trial

Chronic Kidney Disease

Spain
Gachon University Gil Oriental Medical Hospital
DongGuk University; Kyunghee University Medical Center; Wonkwang University Guangju... and other collaborators

Completed

Exploring the Efficacy and Safety of Herbal Medicine on Korean Obese Women With or Without Metabolic Syndrome Risk Factors - A Study Protocol for a Double-blind, Randomised, Multi-center, Placebo-controlled Clinical Trial

Obesity | Metabolic Syndrome

Korea, Republic of
Solvotrin Innovations Ltd

Active, not recruiting

A Clinical Study on Adherence and Efficacy of Different Doses of Active Iron in Treatment Resistant Subjects

Iron-deficiency | Iron Deficiency Anemia | Heavy Menstrual Bleeding | Premenopause | Iron Adverse Reaction

Ireland
Chinese University of Hong Kong
National University Hospital, Singapore; Singapore General Hospital; Changi General... and other collaborators

Completed

Partially Covered Versus Uncovered Pyloro-duodenal Stents for Unresectable Malignant Gastric Outlet Obstruction. A Double Blinded Randomised Controlled Trial.

Unresectable Malignant Gastric Outlet Obstruction

China
PepTcell Limited
Norwegian Institute of Public Health; University Medical Center Groningen; University... and other collaborators

Completed

A Randomised, Double-blind, Placebo-controlled Phase IIb Trial to Test FLU-v Vaccine

Influenza

Netherlands
Prof Gérard WAEBER
Centre Hospitalier Universitaire Vaudois; University of Lausanne; Center for...

Terminated

A Double Blind Randomised Placebo-controlled Trial to Assess the Role of Iron Repletion in Glucose Homeostasis. (DIAFER)

Iron-deficiency | Safety Issues | Metabolic Disorder, Glucose | Iron Toxicity | Glucose Metabolism Disorders (Including Diabetes Mellitus) | Metabolic Side Effects of Drugs

Switzerland
St. Justine's Hospital
Euro-Pharm

Completed

Vitamin D Supplementation in Children With Sickle Cell Disease

Sickle Cell Disease

Canada
University Eye Hospital, Freiburg
German Federal Ministry of Education and Research

Completed

Treatment of Optic Neuritis With Erythropoietin: a Randomised, Double-blind, Placebo-controlled Trial (TONE)

Optic Neuritis

Germany
Oslo University Hospital
Sykehuset Ostfold; Betanien Hospital

Terminated

Intravenous Bisphosphonate in Stress Fracture Treatment -A Randomised Controlled Double Blinded Multicenter Trial

Stress Fracture Foot | Stress Fracture Ankle

Norway
University of Melbourne
The University of Queensland; Swinburne University of Technology

Completed

Kava for the Treatment of Generalised Anxiety Disorder: A Double-Blind Randomised Placebo-Controlled Trial (KGAD)

Generalized Anxiety Disorder

Australia
Instituto de Investigación Hospital Universitario...

Completed

Reparative Therapy in Acute Ischemic Stroke With Allogenic Mesenchymal Stem Cells From Adipose Tissue, Safety Assessment, a Randomised, Double Blind Placebo Controlled Single Center Pilot Clinical Trial (AMASCIS-01)

Ischemic Stroke

Spain
Novo Nordisk A/S

Completed

A Multi-centre, Comparative, Double Blind, Randomised Cross-over Trial Investigating Single Dose Pharmacokinetics and Safety of Turoctocog Alfa Pegol From the Pivotal Process and Turoctocog Alfa Pegol From the Commercial Process in Patients With Severe Haemophilia A (pathfinder™7)

Congenital Bleeding Disorder | Haemophilia A

United States, Netherlands, Spain, Germany, France, Denmark
Shanghai University of Traditional Chinese Medicine
Liaoning University of Traditional Chinese Medicine; Hubei Hospital of Traditional... and other collaborators

Unknown

Tong-Luo-Qu-Tong Plaster for KOA: a Randomised, Double-blind, Parallel Positive Control, Multi-center Clinical Trial

Knee Osteoarthritis | Chronic Musculoskeletal Disease

China
University Hospital Inselspital, Berne
Bern University of Applied Sciences

Terminated

Whole-body Vibration Physiotherapy in Kidney Transplantation

Kidney Transplantation

Switzerland
Mater Misericordiae University Hospital

Completed

Single-shot Pectoral Plane(PECs) Block Versus Continuous Local Anaesthetic Infusion Analgesia or Both PECS Block and Local Anaesthetic Infusion After Breast Surgery: A Prospective Randomised, Double-blind Trial

Breast Diseases | Anesthesia | Block

Ireland
Pfizer

Completed

A Single-centre, Randomised, Double-blind, Placebo-controlled, Four Way Crossover Phase I Study to Investigate the Effect on QT/QTc Interval of Ceftazidime NXL104 or Ceftaroline Fosamil NXL104, Compared With Placebo, Using Moxifloxacin (Avelox®) as a Positive Control, in Healthy Male Volunteers

Healthy Male Volunteers

United States
Novo Nordisk A/S

Completed

A Randomised, Double-blind, Placebo-controlled, Parallel-group Trial to Assess Clinical Efficacy and Safety of NNC0114-0006 in Subjects With Active Crohn's Disease

Inflammation | Crohn's Disease

United States, Spain, Bulgaria, Czech Republic, Poland, Slovakia
University of Copenhagen
Rigshospitalet, Denmark

Completed

Effect of B-cell Depletion in Patients With Primary Sjögren's Syndrome

Fatigue | Keratoconjunctivitis Sicca | Primary Sjögren's Syndrome | Xerostomia | Hyposalivation

Denmark
Birmingham Community Healthcare NHS
NSA, LLC

Completed

Effect of Dietary Intake of Dried Whole Food Concentrates (Juice Plus) on Clinical Outcomes Following Periodontal Therapy: A Pilot Study (BHAM-NSA-05-01)

Periodontitis

United Kingdom
Novo Nordisk A/S

Completed

A Randomised, Double-blind, Placebo-controlled, Parallel-group Trial to Assess Clinical Efficacy of NNC0114-0006 in Subjects With Active Rheumatoid Arthritis

Inflammation | Rheumatoid Arthritis

Spain, Hungary, Serbia, Bulgaria, Poland, Russian Federation, Latvia
Horizon Pharma Ireland, Ltd., Dublin Ireland

Completed

Double-Blind Randomized Crossover Trial to Access Electrocardiogram Effects of HPN-100

Drug Toxicity

United States
Novo Nordisk A/S

Completed

A Randomised, Double-blind, Placebo-controlled Trial to Assess Safety, Tolerability and Pharmacokinetics of Liraglutide in Obese Adolescent Subjects Aged 12 to 17 Years

Obesity | Metabolism and Nutrition Disorder

Germany

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