Search clinical trials for: retinal amyloid

Total 5439 results

NeuroVision Imaging

Recruiting

Effect of LEQEMBI on Cerebral and Retinal Amyloid in Mild Cognitive Impairment Due to Alzheimer's Disease

Alzheimer Disease | Mild Cognitive Impairment

United States
Sanguine Biosciences

Recruiting

Tissue Repository Providing Annotated Biospecimens for Approved Investigator-directed Biomedical Research Initiatives

Heart Diseases | Stroke | Lymphoma | Multiple Sclerosis | Kidney Diseases | Diabetes | Leukemia | Age-Related Macular Degeneration | Cancer | Arthritis | Schizophrenia | Thyroid Diseases | Parkinson Disease | Hepatitis | Vasculitis | Psoriasis | Asthma | Amyloidosis | Fibromyalgia | Graves Disease | Alzheimer Disease | Celiac Disease | Cirr... and other conditions

United States
Amydis Inc.

Recruiting

AMDX-2011P Retinal Tracer in Subjects With Neurodegenerative Diseases Associated With Amyloidogenic Proteinopathy (PROBE)

Parkinson Disease | Amyotrophic Lateral Sclerosis

United States
Oregon Health and Science University

Recruiting

OCT Angiography and NRAI in Dementia

Dementia | Alzheimer Disease | Mild Cognitive Impairment

United States
Janssen Research & Development, LLC

Active, not recruiting

Cognitive Health in Ageing Register: Investigational, Observational and Trial Studies in Dementia Research: Prospective Readiness Cohort Study (CHARIOT:PRO)

Alzheimer's Disease | Plaque, Amyloid

United Kingdom
University of California, Davis
National Institute on Aging (NIA)

Enrolling by invitation

Can (Optical Coherence Tomography) Pictures of the Retina Detect Alzheimer's Disease at Its Earliest Stages?

Alzheimer Disease | Mild Cognitive Impairment

United States
Chippewa Valley Eye Clinic
TA-Sciences

Completed

Telomerase Activator and Retinal Amyloid

Alzheimer Disease

United States
Sutter Health

Completed

Effect of IVIG on Cerebral and Retinal Amyloid in Mild Cognitive Impairment Due to Alzheimer Disease

Mild Cognitive Impairment

United States
Universitaire Ziekenhuizen KU Leuven

Unknown

Optical Coherence Tomography in Cerebral Amyloidosis

Dementia | Alzheimer Disease | Mild Cognitive Impairment | Lewy Body Disease | Dementia Alzheimers | Dementia, Lewy Body

Belgium
GlaxoSmithKline
Quintiles, Inc.

Completed

Pharmacokinetic (PK) Study of GSK933776 in Healthy Volunteers

Atrophy, Geographic

United States
Ray Therapeutics, Inc.

Not yet recruiting

Study to Evaluate Safety of RTx-015 Injection in Retinitis Pigmentosa Patients

Retinitis Pigmentosa

United States
Helse Møre og Romsdal HF

Not yet recruiting

ATTR Cardiac Amyloidosis in a Selected Population

Carpal Tunnel Syndrome | Cardiac Amyloidosis | ATTR Amyloidosis Wild Type | ATTR Gene Mutation
Sohag University

Not yet recruiting

Impact of Diabetes Mellitus on Retinal Microvasculature in Patients Without Clinical Retinopathy Using Optical Coherence Tomography Angiography

Diabetic Retinopathy, DR
Chengdu Origen Biotechnology Co., Ltd.

Not yet recruiting

Safety and Tolerability of KH658 Gene Therapy in Subjects With Neovascular Age-related Macular Degeneration (nAMD)

Age-related Macular Degeneration

China
Yongyong MA

Recruiting

Daratumumab/Daratumumab and Hyaluronidase-fihj in Combination With Pomalidomide and Dexamethasone for the Treatment of Patients With Newly Diagnosed AL Amyloidosis: a Prospective, Multicenter, Single-arm Study

Amyloid Light-chain Amyloidosis

China
PYC Therapeutics

Not yet recruiting

MAD of IVT VP-001 in PRPF31 Mutation-Associated Retinal Dystrophy Subjects (Wallaby)

Eye Diseases | Retinal Degeneration | Retinal Dystrophies | Retinal Disease | Retinitis Pigmentosa 11

United States
Unity Health Toronto

Not yet recruiting

The Genetics Navigator: Evaluating a Digital Platform for Genomics Health Services

Connective Tissue Diseases | Neurodevelopmental Disorders | Retinal Disease | Epilepsy in Children | Cardiac Conditions

Canada
Duke University
National Eye Institute (NEI); National Institutes of Health (NIH)

Not yet recruiting

Peripheral Retina Robotically Aligned OCT Study (PR-RAOCT)

Retinal Disease

United States
Ascidian Therapeutics, Inc

Recruiting

Prescreening Study to Identify Potential Participants for ACDN-01 Clinical Trials

Stargardt Disease | Stargardt Disease 1 | Juvenile Macular Degeneration | Cone Rod Dystrophy

United States
Hoffmann-La Roche
Shanghai Roche Pharmaceutical Co., Ltd

Recruiting

Real World Evidence in China: Faricimab Use in Diabetic Macular Edema, Retinal Vein Occlusion, and Neovascular Age-Related Macular Degeneration (The Farseeing Study)

Diabetic Macular Edema | Retinal Vein Occlusion | Neovascular Age-related Macular Degeneration

China
Washington University School of Medicine

Recruiting

Beta Amyloid PET Imaging for Alzheimer Disease With [18F]-Fluselenamyl

Alzheimer Disease

United States
Splice Bio

Recruiting

An Observational Study in Subjects to Follow the Progression of Stargardt Disease Type 1 (STGD1) Caused by Bi-Allelic Autosomal Recessive Mutations in the ABCA4 Gene (POLARIS)

Stargardt Disease | Stargardt's Disease | STGD1 | Stargardt
Walailak University

Not yet recruiting

Comparative Study of Decellularized Human Amniotic Membrane Hydrogel and Inverted Internal Limiting Membrane Flap in Idiopathic Large Macular Holes (MACROHOLE)

Macular Holes
Zhejiang Provincial People's Hospital

Recruiting

Fundus Optical coheRence Tomography Angiography Evaluation for Small-vessel Health in Cerebral Small Vessel Disease (FRESH-CSVD)

Cerebral Small Vessel Diseases | Retinal Ischemia | Choroid; Injury

China
Bayer

Not yet recruiting

A Study to Learn About the Safety of BAY3283142 in People With Mild to Moderate High Blood Pressure

Chronic Kidney Disease | Arterial Hypertension | Non-proliferative Diabetic Retinopathy

Germany
Gérond'if

Not yet recruiting

Cardiac Amyloidosis pRevaleNce of in OLDer Subjects Affected by Heart Failure (ARNOLD)

Cardiac Amyloidosis

France
Eye & ENT Hospital of Fudan University
The Eye Hospital of Wenzhou Medical University

Not yet recruiting

Targeting NUDT21 siRNA Drugs for Patients With Refractory Retinoblastoma

Retinoblastoma | Refractory
Massachusetts Eye and Ear Infirmary

Not yet recruiting

The Safety and Efficacy of Intravitreal Topotecan for the Treatment of Proliferative Vitreoretinopathy

Rhegmatogenous Retinal Detachment | Proliferative Vitreoretinopathy | Proliferative Vitreo-Retinopathy
Zhejiang University

Not yet recruiting

Comparing Artificial Intelligence for Assisted Diagnosis of Diabetic Retinopathy

Diabetic Retinopathy | Diabetic Macular Edema

China
Bayer
Regeneron Pharmaceuticals

Recruiting

A Study to Learn More About How Well 8 Milligram Aflibercept Works and How Safe it is in Chinese Participants With Diabetic Macular Edema (PHOTONiC)

Diabetic Macular Edema

China, Hong Kong
Leiden University Medical Center
The Dutch Brain Foundation (funding)

Not yet recruiting

Stimulating Amyloid Clearance in Cerebral Amyloid Angiopathy (Clear-Brain)

Cerebral Amyloid Angiopathy
Jeffrey Zonder

Not yet recruiting

DapagliFLOzin in Renal AL Amyloidosis (FLORAL) (FLORAL)

Renal AL Amyloidosis

United States
Peking University People's Hospital

Recruiting

Daratumumab, Bortezomib, Cyclophosphamide, and Dexamethasone Therapy for Patients With MIDD

Monoclonal Gammopathy of Renal Significance

China
University of Edinburgh

Not yet recruiting

Retinal Vessel Leakage in Cerebral Small Vessel Disease

Cerebral Small Vessel Diseases | Vascular Dementia | Lacunar Stroke
AstraZeneca

Recruiting

Hereditary Transthyretin Amyloidosis Polyneuropathy in Patients With Carpal Tunnel Syndrome in Russia (LOCUS)

Carpal Tunnel Syndrome | Amyloidosis | Polyneuropathy | Hereditary Transthyretin Amyloidosis

Russian Federation
Li Xiaorong
Shanghai Refreshgene Technology Co., Ltd.

Recruiting

The Preliminary Safety and Efficacy of RRG001 After Vitrectomy in Subjects With Proliferative Diabetic Retinopathy (PDR)

PDR - Proliferative Diabetic Retinopathy

China
University Hospital, Ghent

Recruiting

Amyloid PET in Patients With Mild Cognitive Impairment and Early Dementia

MCI

Belgium
Regeneron Pharmaceuticals

Not yet recruiting

An Observational Study to Investigate the Use of Aflibercept 8 mg to Treat Adult Patients With Neovascular Age-Related Macular Degeneration (nAMD) and Diabetic Macular Edema (DME) in a Real-World Setting (SPECTRUM-US)

Visual Impairment | Diabetic Macular Edema (DME) | Neovascular Age-related Macular Degeneration (nAMD) | Wet Age-related Macular Degeneration (AMD)
Academisch Medisch Centrum - Universiteit van Amsterdam...

Recruiting

The Role of Red Cell Characteristics, Angiogenesis, Viscosity and Oxygenation in the Pathophysiology of Sickle Cell Related Retinopathy (RAVOS)

Sickle Cell Disease | Sickle Cell SC Disease | Sickle Cell-SS Disease | Sickle Cell Retinopathy

Netherlands
Shanghai Yao Yuan Biotechnology Ltd. (also known...

Not yet recruiting

Evaluating the Safety and Tolerability of Orally Administered DF-003 in ROSAH Syndrome Patients

ROSAH

Australia, United States
Alnylam Pharmaceuticals

Recruiting

A Phase 2 Trial of ALN-APP in Patients With Cerebral Amyloid Angiopathy (cAPPricorn-1)

Cerebral Amyloid Angiopathy

Canada
Eyestem Research Pvt. Ltd.

Recruiting

Safety & Efficacy of Eyecyte-RPE™ in Patients With Geographic Atrophy Secondary to Dry Age-related Macular Degeneration.

Eye Diseases | Age-Related Macular Degeneration | Macular Degeneration | Geographic Atrophy | Retinal Disease

India
Pfizer

Recruiting

Real-World Effectiveness of High-Dose Tafamidis on Neurologic Disease Progression in Mixed-Phenotype Transthyretin Amyloid Cardiomyopathy

Transthyretin Amyloidosis Cardiomyopathy (ATTR-CM)

United States
Ocugen

Recruiting

A Phase 3 Study Of OCU400 Gene Therapy for the Treatment Of Retinitis Pigmentosa (liMeliGhT)

Retinitis Pigmentosa

United States
Belite Bio, Inc

Not yet recruiting

A Phase 2/3 Study to Evaluate the Efficacy and Safety of Tinlarebant in Subjects With Stargardt Disease (DRAGON II)

Stargardt Disease 1 | STGD1

United States
Washington University School of Medicine
Alzheimer's Association; Eisai Inc.

Not yet recruiting

DIAN-TU Amyloid Removal Trial (ART) in Dominantly Inherited Alzheimer's Disease (DIAN-TU)

Dementia | Alzheimer's Disease | Alzheimer's Disease, Familial

United States, Australia, United Kingdom
IRCCS Policlinico S. Matteo

Recruiting

Promoting Diagnosis and Management of AL in Italy (ProDigALIty) (ProDigALIty)

AL Amyloidosis | Monoclonal Gammopathy of Undetermined Significance | Smoldering Multiple Myeloma

Italy
University of Wisconsin, Madison

Recruiting

Retinal Fundus Flavoprotein Fluorescence in Age Related Macular Degeneration (FPF in AMD)

Age-Related Macular Degeneration | Geographic Atrophy

United States
University of Wisconsin, Madison

Not yet recruiting

COmparison of Clarus and Optos Ultrawide Field Imaging Systems for Inherited Retinal Disease (COCO-IRD)

Retinal Disease

United States
Nanjing University School of Medicine

Recruiting

Daratumumab for Patients With Light Chain Amyloidosis

Light Chain (AL) Amyloidosis

China

Search clinical trials for: retinal amyloid

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