Search clinical trials for: safety and efficacy

Total 470166 results

Incyte Biosciences Japan GK

Not yet recruiting

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Axatilimab Monotherapy in Japanese Participants With Recurrent or Refractory Active Chronic Graft-Versus-Host Disease

Chronic Graft-versus-host-disease
Materia Medica Holding

Recruiting

Clinical Trial of the Efficacy and Safety of Raphamin in Combined Treatment of Community-acquired Pneumonia

Pneumonia | Community-acquired Pneumonia

Russian Federation
Henan Provincial People's Hospital

Not yet recruiting

Safety and Efficacy of Fospropofol vs Propofol During Invasive Mechanical Ventilation.

Invasive Mechanical Ventilation
Medical University of Warsaw

Recruiting

Efficacy and Safety of Low-dose Sesame Oral Immunotherapy in Pediatric Patients

Food Allergy

Poland
All India Institute of Medical Sciences, Bhubaneswar

Not yet recruiting

Efficacy and Safety of add-on Apremilast Versus add-on Methotrexate in Patients With Oral Lichen Planus

Oral Lichen Planus

India
hemotune AG

Not yet recruiting

First in Human Trial to Assess the Safety & Efficacy of HemoSystem REBOOT in Patients With Sepsis-induced Immunosuppression ((RESTORE))

Septic Shock

Switzerland
Glyscend, Inc.

Not yet recruiting

A 16-Week Study to Evaluate the Efficacy, Safety, and Tolerability of GLY-200 in Participants With Obesity

Obesity

United States
Herbarium Laboratorio Botanico Ltda

Not yet recruiting

Efficacy and Safety Study of Products Based on Tribulus Terrestris, L. in Men With Oligospermia

Oligospermia
Hongmeng Yu

Recruiting

Efficacy and Safety of Induction Chemotherapy for Olfactory Neuroblastoma (ESICON) (ESICON)

Olfactory Neuroblastoma

China
AMIpharm Co., Ltd.

Recruiting

Evaluate the Efficacy and Safety of AYP-101 for the Reduction of Submental Fat in Chin Area

Healthy

Korea, Republic of
Claris Biotherapeutics, Inc.

Recruiting

Study to Evaluate the Safety and Efficacy of CSB-001 Ophthalmic Solution 0.1% in Subjects With Corneal Scars

Corneal Scar

United States
Ono Pharmaceutical Co. Ltd

Recruiting

A Study to Investigate the Efficacy and Safety of ONO-4578 in Combination With Nivolumab and Chemotherapy in Chemotherapy-naïve Participants With HER2-negative Unresectable Advanced or Recurrent Gastric Cancer (Including Esophagogastric Junction Cancer)

Gastric Cancer

Japan
Beijing Tiantan Hospital
SDM Bio Service Inc.

Recruiting

A Study Evaluating the Safety and Efficacy of Neuroprotective Peptide CN-105 Peptide in Patients With Acute Supratentorial Intracerebral Hemorrhage

Intracerebral Hemorrhage

China
McGill University Health Centre/Research Institute...
The Hospital for Sick Children

Recruiting

Investigating Modified Protocols of Oral Immunotherapy to Validate Efficacy and Safety (IMPROVES)

Egg Allergy | Peanut Allergy | Milk Allergy, Cow's

Canada
Xijing Hospital

Recruiting

Safety and Efficacy of Post-marketing Transcatheter Aortic Valves in "Real World" Chinese Patients

Aortic Valve Disease Mixed

China
Tianjin Eye Hospital

Recruiting

Evaluation of the Safety and Efficacy of Rigid Breathable Scleral Contact Lenses for the Correction of Ametropia

Corneal Astigmatism | Ocular Surface Disease | Contact Lens Complication | Irregular Astigmatism

China
Ruijin Hospital

Not yet recruiting

The Efficacy and Safety of Chidamide, Anti-PD-1 Antibody in Combination With Pegaspargase Versus DDGP in the Treatment of Newly Diagnosed, Stage III to IV Extranodal Natural Killer/T-Cell Lymphoma

Extranodal Natural Killer T Cell Lymphoma

China
Atara Biotherapeutics

Recruiting

A Study to Evaluate the Safety and Preliminary Efficacy of ATA3219 in Participants With Relapsed/Refractory B-cell Non-Hodgkin Lymphoma

High-grade B-cell Lymphoma | MCL | Diffuse Large B-cell Lymphoma (DLBCL) | Relapsed/Refractory B-cell Non-Hodgkin Lymphoma | DLBCL/High-grade B-cell Lymphoma With MYC and BCL2 Rearrangements | Anaplastic Lymphoma Kinase-Positive Large B-Cell Lymphoma | LBCL With IRF4 Rearrangement | High-grade B-cell... and other conditions

United States
Institute of Hematology & Blood Diseases Hospital...
Fosun Pharmaceutical Distribution Jiangsu co., Limited

Not yet recruiting

Efficacy and Safety of Avatrombopag vs. Avatrombopag Combined With rhTPO in the Treatment of SAA

Anemia, Aplastic
Beijing Tiantan Hospital
ZhongSheng BioTech Inc.

Recruiting

Safety and Efficacy Study for DC Vaccine in Recurrent or Progressive High-grade Gliomas

WHO Grade III Gliomas | WHO Grade IV Gliomas

China
Oystershell NV
Eurofins

Not yet recruiting

Clinical Investigation for the Evaluation of Efficacy and Safety of Two Medical Devices for Onychomycosis Treatment

Onychomycosis
First Affiliated Hospital Bengbu Medical College

Not yet recruiting

Efficacy and Safety of Intratumoral Injection of Recombinant Human Adenovirus Type 5 Combined With Tislelizumab and Lenvatinib in the Treatment of Advanced Hepatocellular Carcinoma

Hepatocellular Carcinoma
PTC Therapeutics

Recruiting

An Extension Study to Evaluate the Long-Term Safety and Efficacy of PTC518 in Participants With Huntington's Disease (HD)

Huntington Disease

Australia, France, Germany, Netherlands, United Kingdom, Spain, Austria, Canada, Italy, New Zealand
Sirtsei Pharmaceuticals, Inc.
Rho, Inc.

Recruiting

A Study of the Efficacy and Safety of SP-624 in the Treatment of Adults With Major Depressive Disorder

Major Depressive Disorder

United States
Shandong Suncadia Medicine Co., Ltd.

Not yet recruiting

Efficacy and Safety of HRS-7535 Tablets in Obese Subjects .

Overweight and Obesity
Shanghai 6th People's Hospital

Not yet recruiting

Efficacy and Safety of Fospropofol for Same-day Bidirectional Endoscopy in Elderly Patients

Elderly Patients
Shanghai General Hospital, Shanghai Jiao Tong University...
Shenzhen Zhongke Qiyuan Biotechnology Co., Ltd.

Recruiting

Clinical Study on the Safety and Efficacy of QY-1-T in the Treatment of HBV-associated Advanced Liver Cancer

Liver Cancer

China
Tanta University

Recruiting

Comparative Clinical Study to Evaluate the Possible Efficacy and Safety of Oral N-Acetyl Cysteine Versus Rectal Diclofenac in the Prevention of Post Endoscopic Retrograde Cholangiopancreatography Pancreatitis

Post ERCP Pancreatitis

Egypt
Yonsei University

Not yet recruiting

Efficacy and Safety of T-DXd in HER2-mutant Advanced Lung Cancer Patients With Asymptomatic Brain Metastases (ELPIS)

Non Small Cell Lung Cancer

Korea, Republic of
Hangzhou Grand Biologic Pharmaceutical, Inc.

Not yet recruiting

Efficacy and Safety of Histamine Human Immunoglobulin in the Treatment of Chronic Spontaneous Urticaria (CSU)

Chronic Spontaneous Urticaria
Sanofi Pasteur, a Sanofi Company

Recruiting

Efficacy, Immunogenicity, and Safety Study of a Respiratory Syncytial Virus Vaccine in Infants and Toddlers (PEARL)

RSV Immunisation

United States, Argentina, Honduras
Fundación Pública Andaluza para la Investigación...

Not yet recruiting

Proof-of-concept to Evaluate the Efficacy and Safety of Prednisone in Idiosyncratic Hepatotoxicity (DILICORT)

Prednisone | Hepatotoxicity | Idiosyncratic Drug Effect
Pharming Technologies B.V.
Laboratory Corporation of America; CMIC Co, Ltd. Japan; Axial Biotech, Inc

Recruiting

An Open-Label Study to Assess the Safety & Efficacy of Leniolisib in Japanese Patients With APDS

APDS Gene Mutation

Japan
Neuracle Science Co., LTD.
Samsung Medical Center; Korea University Anam Hospital; Severance Hospital

Recruiting

A Phase 1b/2a, Study Evaluating the Safety, PK/PD and Efficacy of NS101 in Healthy Volunteers and SSNHL Patients

Sudden Sensorineural Hearing Loss | Seneorineural Deafness

Korea, Republic of
Kowa Research Institute, Inc.

Recruiting

Study to Evaluate the Efficacy and Safety of K-808 (Pemafibrate) in Participants With Primary Biliary Cholangitis (PBC) With Inadequate Response to Ursodeoxycholic Acid (UDCA) and/or Obeticholic Acid (OCA) Treatment.

Primary Biliary Cholangitis

United States, Japan
Ruijin Hospital

Recruiting

Evaluate the Efficacy and Safety of Allogeneic Haematopoietic Stem Cell Transplantation With FBM Conditioning for MDS

Myelodysplastic Syndromes | Myelodysplastic Syndrome With Excess Blasts-2 | Myelodysplastic Syndrome With Excess Blasts-1

China
L&C Bio
PROMeDis

Recruiting

Clinical Trial to Evaluate the Efficacy and Safety of MegaCarti^® in Knee Cartilage Defects

Osteoarthritis, Knee

Korea, Republic of
Korea Institute of Oriental Medicine

Recruiting

Efficacy and Safety of Combination Therapy With Bojungikki-tang and Pembrolizumab Monotherapy in Patients With Advanced Non-small Cell Lung Cancer

Non-small Cell Lung Cancer

Korea, Republic of
Jetema USA Inc.

Not yet recruiting

Clinical Trial to Evaluate the Safety and Efficacy of JTM201 to Treat Moderate or Severe Glabellar Lines

Glabellar Lines
Istituto Oncologico Veneto IRCCS
Fidia Farmaceutici s.p.a.

Not yet recruiting

A Study to Evaluate Efficacy and Safety of Hydeal Cyst® Intravesical Instillations in Patients Treated With Intravesical Chemotherapy or Immunotherapy in Non-muscle Invasive Bladder Cancer (Hydeal Cyst)

Non-muscle Invasive Bladder Cancer

Italy
Hanlim Pharm. Co., Ltd.

Recruiting

Evaluation of the Clinical Efficacy and Safety of BriTurn Injection or BrisTurn Prefilled Injection

Reversal of Neuromuscular Blockade

Korea, Republic of
Guangzhou Zhiyi Biotechnology Co., Ltd.

Recruiting

A Study to Evaluate the Efficacy and Safety of Live SK08 Powder in Patients With IBS-D

Irritable Bowel Syndrome With Diarrhea

China
Travere Therapeutics, Inc.

Recruiting

A Study to Investigate Efficacy and Safety of Pegtibatinase Compared With Placebo in Participants ≥12 to ≤65 Years of Age With Classical Homocystinuria (HCU) Due to Cystathionine Beta Synthase Deficiency Receiving Standard of Care Treatment (HARMONY)

Homocystinuria

United States
Horus Pharma
Eurofins Dermscan Pharmascan

Recruiting

Evaluation of the Efficacy and Safety of DM934 Versus Théalose on Eye Dryness

Dry Eye

France, Poland, Spain, United Kingdom
Nuwacell Biotechnologies Co., Ltd.

Not yet recruiting

A Trial to Evaluate the Safety and Preliminary Efficacy of iNK in the Treatment of Subjects With Solid Tumor

Solid Tumor
Amgen

Recruiting

A Safety and Efficacy Study of Dazodalibep in Participants With Sjögren's Syndrome (SS) With Moderate-to-Severe Symptom State

Sjögren's Syndrome (SS)

United States
SF Research Institute, Inc.

Recruiting

Long Term Safety and Efficacy of KSM-66 Ashwagandha in Adults

All

United States
Xiangya Hospital of Central South University

Recruiting

Efficacy and Safety of NSCLC Patients With/Without Adjuvant Immunotherapy Who Have Achieved pCR After Neoadjuvant Immunotherapy

Resectable/Potentially Resectable NSCLC

China
Guangdong Provincial People's Hospital

Not yet recruiting

The Safety and Efficacy of Autologous Transfusion in Spinal Surgery for Lung Cancer With Spinal Metastasis

Lung Cancer | Surgery | Autologous Blood Transfusion | Spinal Metastases | Blood Transfusion Complication
Sichuan Cancer Hospital and Research Institute

Not yet recruiting

Study on the Safety and Efficacy of MR-Linac Technique in Patients With Unresectable Locally Advanced Colon Cancer (UNLACC)

Safety and Efficacy

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