Search clinical trials for: sever dry eye,keratoconjunctivitis sicca

Total 16486 results

Laboratoires Thea

Not yet recruiting

Comparison of the Performance and Safety of T2769 Versus Hylo-Forte® in the Treatment of Moderate to Severe Dry Eye Syndrome.

Dry Eye Syndrome
Invirsa, Inc.

Recruiting

Study of INV-102 Ophthalmic Solution in Adults With Moderate to Severe Dry Eye Disease

Dry Eye Disease

United States
Fidia Farmaceutici s.p.a.

Recruiting

Assessment of Efficacy and Safety of the Use of Two Eye Gel Products Containing 5% Dexpanthenol in Patients With Moderate to Severe Dry Eye Syndrome

Dry Eye Disease

Italy
Nu Eyne Co., Ltd.

Recruiting

Study of Application of Pulse Electrical Stimulation Around Eye in Dry Eye Disease Patients Who Are Scheduled for Laser Epithelial Keratomileusis (LASEK) Surgery

Dry Eye Disease

Korea, Republic of
Laboratoires Thea

Recruiting

Comparison of the Performance and Safety of T2769 Versus Vismed® Multi in the Treatment of Moderate to Severe Dry Eye Syndrome

Dry Eye

France
Taejoon Pharmaceutical Co., Ltd.

Recruiting

Evaluating the Efficacy and Safety of TJO-087 in Moderate to Severe Dry Eye Disease Patients

Dry Eye Syndrome

Korea, Republic of
Yonsei University

Recruiting

A Clinical Trial to Evaluate the Clinical Efficacy of Cyclosporine 0.1% (Ikervis®) for Moderate to Severe Dry Eye Patients. (IKE-03-SWITCHING)

Moderate to Severe Dry Eye

Korea, Republic of
Harbour BioMed (Guangzhou) Co. Ltd.

Recruiting

A Study Evaluating HBM9036 Efficacy and Safety on Moderate to Severe Dry Eye

Dry Eye

China
Fondation Ophtalmologique Adolphe de Rothschild

Recruiting

Three-dimensional Analysis of EMMPRIN on Conjunctival Epithelial Cells Surface in Severe Dry Eye Syndrome (ALTESSE) (ALTESSE)

Dry Eye Syndromes | Conjunctival Diseases

France
Dompé Farmaceutici S.p.A

Completed

A Study to Evaluate Safety and Efficacy of rhNGF Eye Solution vs Vehicle in Patients With Moderate to Severe Dry Eye

Dry Eye Syndrome

United States
Jadran Galenski laboratorij d.d.
Poseidon CRO

Completed

Vizol S Lipid Balance Efficacy and Safety Study in Patients With Dry Eye

Dry Eye Disease

Serbia
SCAI Therapeutics

Completed

Clinical Trial to Evaluate the Safety and Efficacy of SCAI-001 Compared to Restasis

Dry Eye Syndromes

Korea, Republic of
Dompé Farmaceutici S.p.A

Completed

Study to Evaluate Safety and Efficacy of Cenegermin (Oxervate®) vs Vehicle in Severe Sjogren's Dry Eye Disease (NGF0221)

Dry Eye Syndrome

United States, Italy
Kowa Research Institute, Inc.

Completed

A Study to Confirm the Efficacy and Safety of K-161 Ophthalmic Solution for Treatment of Moderate to Severe Dry Eye Disease

Dry Eye Disease

United States
Centro Oculistico Borroni

Completed

Quantum Molecular Resonance Electrotherapy in Severe Dry Eye Disease (QMR)

Dry Eye

Italy
Santen SAS

Completed

3-year Study in Dry Eye Disease Patients With Severe Keratitis Receiving Ikervis® (1mg/mL Ciclosporin)

Dry Eye Disease With Severe Keratitis

Czechia, France, Italy, Poland, Russian Federation, Spain, Turkey
Eximore Ltd.

Active, not recruiting

Safety, Tolerability, Plug Retention and Preliminary Efficacy of Tacrolimus-loaded Punctal Plug in Patients With Moderate to Severe Dry Eye Disease - Cohort B

Ocular Inflammation | Dry Eye | Keratoconjunctivitis Sicca

Mexico
Dompé Farmaceutici S.p.A

Active, not recruiting

Study to Evaluate Safety and Efficacy of Cenegermin (Oxervate®) vs Vehicle in Severe Sjogren's Dry Eye Disease (NGF0121 - PROTEGO-1 Study) (NGF0121)

Dry Eye

United States, Italy
Kowa Research Institute, Inc.

Completed

A Study Assessing the Safety, Efficacy, and Optimum Dosage of K-161 in Subjects With Moderate to Severe Dry Eye Disease

Dry Eye Disease

United States
SIFI SpA

Completed

Safety and Efficacy of Two Different Concentrations (0.5% and 1%) of Progesterone Topical Gel Compared to Placebo in Patients Diagnosed With Moderate to Severe Dry Eye Syndrome (ProGIFT)

Dry Eye Disease

Italy
Yonsei University

Completed

Effect of ADDE on Tear Interferometry

Dry Eye Syndromes | Tear

Korea, Republic of
Zhaoke (Guangzhou) Ophthalmology Pharmaceutical...

Completed

Assess the Safety and Efficacy of CsA Ophthalmic Gel in Subjects With Moderate to Severe Dry Eye Disease

Dry Eye

China
Universidad Nacional de Colombia

Completed

Platelet -Rich Plasma (PRP) Injection for the Treatment of Severe Dry Eye

Dry Eye | Sjogren Syndrome
Harbour BioMed (Guangzhou) Co. Ltd.

Completed

A Study Evaluating the Efficacy and Safety on Moderate to Severe Dry Eye

Dry Eye

China
Instituto Universitario de Oftalmobiología Aplicada...
Santen Oy

Completed

Efficacy and Safety of Ikervis Under Controlled Environmental Conditions Environment

Dry Eye | Dry Eye Syndromes | Severe Keratitis

Spain
Epitech Mag Ltd.

Terminated

Viveye Ocular Magnetic Neurostimulation System (OMNS) for the Management of Severe Dry Eye Disease (OMNS)

Dry Eye Syndromes | Sjogren's Syndrome | ATD

Israel
Singapore National Eye Centre
Health Science Authority Singapore

Withdrawn

Autologous Plasma Treatment for Severe Dry Eye Patients

Dry Eye

Singapore
National University of Malaysia

Unknown

Umbilical Cord Serum Versus Conventional Eyedrops

Dry Eye Syndromes

Malaysia
Novartis

Completed

Safety and Efficacy of Pimecrolimus Ophthalmic Suspension in Patients With Moderate to Severe Keratoconjunctivitis Sicca

Keratoconjunctivitis Sicca

United States
Huons Co., Ltd.

Completed

Efficacy and Safety of HU007 Eye Drops in Patients With Dry Eye Syndrome

Dry Eye Syndrome

Korea, Republic of
University of Illinois at Chicago
Johnson & Johnson Vision Care, Inc.

Unknown

Senofilcon A Lenses in Moderate to Severe Dry Eye Disease

Moderate to Severe Dry Eye Disease

United States
Kuopio University Hospital
Business Finland; 4Pharma Ltd.; Finnsusp Ltd.

Completed

Piiloset Trehalose Emulsion Eye Drop Study in Moderate or Severe Dry Eye

Dry Eye Syndrome

Finland
University of Miami

Completed

Can Pregabalin Reduce the Frequency and Severity of Dry Eye Symptoms After Laser-assisted in Situ Keratomileusis?

Dry Eye

United States
Novaliq GmbH

Completed

CyclASol for the Treatment of Moderate to Severe Dry-eye Disease (DED)

Dry Eye Syndromes

United States
R-Tech Ueno, Ltd.

Completed

A Phase 1/2, RU-101 Ophthalmic Solution in Patients With Severe Dry Eye

Dry Eye

United States
Medical University of Vienna

Completed

Difference in the Frequency of Use of Lachrymal Substitutes in Patients With Moderate to Severe Dry Eye Syndrome

Dry Eye Syndromes

Austria
Medical University of Vienna

Completed

Influence of Three Different Formulations of Lachrymal Substitutes on Tear Film Thickness and Other Signs and Symptoms in Patients With Moderate to Severe Dry Eye Syndrome

Dry Eye Syndromes

Austria
Sylentis, S.A.

Completed

HELIX, a Double-masked Study of SYL1001 in Patients With Moderate to Severe Dry Eye Disease (DED)

Dry Eye Disease

Spain, Portugal, Italy, Estonia, Germany, Slovakia
Seref istek
Usak State Hospital

Completed

The Comparison of 50% AS Versus PFAT+ 0.05 % COE in Severe Dry Eye Syndrome

Dry Eye Syndrome
Pontificia Universidad Catolica de Chile
Hospital Dr Sotero del Rio

Unknown

Efficacy of Two Concentrations of Autologous Serum for the Treatment of Severe Dry Eye

Dry Eye | Keratoconjunctivitis Sicca | Lacrimal Apparatus Diseases | Conjunctival Diseases | Keratitis | Corneal Diseases | Sjogren's Syndrome

Chile
Alcon, a Novartis Company
Novartis Institutes for BioMedical Research

Completed

LME636 in the Relief of Persistent Ocular Discomfort in Subjects With Severe Dry Eye Disease

Dry Eye
Bedford Hospital NHS Trust
Anglia Ruskin University

Unknown

Fingerprick Autologous Blood (FAB) in Severe Dry Eye Disease (DED) (FAB)

Dry Eye Syndromes
Yungjin Pharm. Co., Ltd.

Completed

Phase 2 Study to Evaluation the Safety and Efficacy of Orally Administered KL7016 in Patients With Dry Eye Syndrome

Dry Eye Syndrome

Korea, Republic of
Minia University

Completed

The Effect of Ablation Depth on Dry Eye After LASIK Treatment of Myopia

Incidence and Severity of Dry Eye After Myopic LASIK
Medical University of Vienna

Completed

Added Benefits of Lachrymal Substitute Gel During the Night in Patients With Moderate to Severe Dry Eye Syndrome

Dry Eye Syndromes

Austria
Laboratoires Thea

Terminated

Comparison of the Efficacy and Safety of T2762 Versus Optive® in the Treatment of Moderate to Severe Dry Eye Syndrome

Dry Eye Syndrome

France
Allergan

Completed

A Study to Compare a New Eye Drop Formulation With Systane® Gel Drops and Genteal® Lubricant Gel Drops for Moderate to Severe Dry Eye Relief

Dry Eye Syndromes

United States
Chong Kun Dang Pharmaceutical

Unknown

Study to Evaluate the Efficacy and Safety of CKD-350

Dry Eye Syndrome

Korea, Republic of
Laboratoires Thea

Completed

Comparison of the Efficacy and Safety of T2750 and Vismed® in the Treatment of Moderate to Severe Dry Eye Syndrome

Dry Eye Syndromes

France
Michigan Cornea Consultants, PC
Kresge Eye Institute

Completed

Comparative Study of Thymosin Beta 4 Eye Drops vs. Vehicle in the Treatment of Severe Dry Eye

Dry Eye | Sjogren's Syndrome | Graft vs. Host Disease

United States

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