Search clinical trials for: severe eosinophilic asthma, late-onset, fixed obstruction

Total 12615 results

Aristotle University Of Thessaloniki
NHS Pulmonary Clinic G. Papanikolaou Hospital, Thessaloniki, Greece; Pulmonary... and other collaborators

Active, not recruiting

Efficacy of Mepolizumab in Severe Asthmatics on a Long Term (MESILICO) (MESILICO)

Severe Asthma | Asthma; Eosinophilic | Late-Onset Asthma

Greece
Hat Yai Medical Education Center

Recruiting

Role of Parasympathetic Activity in Mild to Severe Asthma With Fixed Airway Obstruction (PARASMA Study) (PARASMA)

Asthma | Airway Obstruction | Airway Remodeling | Parasympathetic Nervous System Diseases

Thailand
AstraZeneca

Completed

Efficacy, Safety and Tolerability of Two Fixed Dose Combinations of Aclidinium Bromide/Formoterol Fumarate, Aclidinium Bromide, Formoterol Fumarate and Placebo for 28-Weeks Treatment in Patients With Moderate to Severe, Stable Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease

United States, Australia, Canada, New Zealand
AstraZeneca

Completed

Pharmacokinetic, Safety and Tolerability Study of Aclidinium/Formoterol Fixed Dose Combination and Formoterol in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease (COPD)

United States
AstraZeneca

Not yet recruiting

A Non-interventional, Prospective Study With Benralizumab (AIR POWER)

Asthma, Bronchial
Saint Petersburg State University, Russia

Not yet recruiting

Influence of Lung Ultrasonography on the Prognosis and Postoperative Outcomes in Cardiac Surgical Patients

Ischemic Heart Disease | Mitral Insufficiency | Aortic Stenosis, Severe | Mitral Stenosis | Aortic Insufficiency | Ascending Aortic Aneurysm | Mitral Stenosis With Insufficiency | Tricuspid Insufficiency

Russian Federation
University of North Carolina, Chapel Hill
Sanofi; Regeneron Pharmaceuticals

Not yet recruiting

Dupilumab for Eosinophilic Esophagitis With Severe Strictures (DESTRICT)

Eosinophilic Esophagitis | EoE

United States
AstraZeneca
Parexel

Not yet recruiting

A Study to Assess the Lung Exposure Bioequivalence of Budesonide, Glycopyrronium, & Formoterol (BGF) Metered Dose Inhaler (MDI) Hydrofluoroolefin (HFO) With a Spacer (Treatment B), BGF MDI Hydrofluoroalkane (HFA) With a Spacer (Treatment A), as Well as BGF MDI HFO Without a Spacer (Treatment C)

Healthy

Germany
Medical University of Graz

Not yet recruiting

Clock Proteins as Prognostic Markers (CLOCK-PM)

Severe Eosinophilic Asthma
Aristotle University Of Thessaloniki
University Hospital of Crete; University Hospital of Patras; Pulmonary Clinic... and other collaborators

Recruiting

BenRalizumab Effect on Airway Remodeling in Severe asTHma (BREATH)

Airway Remodeling | Asthma; Eosinophilic

Greece
Qilu Hospital of Shandong University

Recruiting

Effects of Levosimendan on Cardiac Function After TAVR in Patients With Heart Failure

Heart Failure | Aortic Stenosis, Severe

China
Hospital Universitario La Paz

Not yet recruiting

VARC-TAVI VALVE IMPLANTATION) (VARC-TAVI)

Severe Aortic Stenosis | Vascular Complications | TAVI\(Transcatheter Aortic Valve Implantation\)
Second Affiliated Hospital, School of Medicine,...

Recruiting

Comparison of a Single Versus Double Perclose Technique for TAVR (Single)

Severe Aortic Stenosis

China
Massachusetts General Hospital
Patient-Centered Outcomes Research Institute; University of Colorado, Denver; Emory University and other collaborators

Not yet recruiting

Promoting Shared Decision Making for Severe Aortic Stenosis (IMPACT SDM)

Aortic Stenosis

United States
St. Antonius Hospital

Recruiting

Future Optimal Research and Care Evaluation - Aortic Stenosis (FORCE-AoS)

Severe Aortic Valve Stenosis | Moderate Aortic Valve Stenosis

Netherlands
St. Antonius Hospital
ZonMw: The Netherlands Organisation for Health Research and Development; Pitié-Salpêtrière...

Recruiting

Personalized, CT-guided Antithrombotic Therapy Versus Lifelong Single Antiplatelet Therapy to Reduce Thromboembolic and Bleeding Events in Non-atrial Fibrillation Patients After Transcatheter Aortic Valve Implantation (POP ATLANTIS)

Severe Aortic Valve Stenosis

Netherlands
University of Manitoba

Recruiting

Post Spinal Hemodynamic Changes in Aortic Stenosis and Mitral Regurgitation by VIS Index and Echocardiography

Severe Aortic Valve Stenosis | Severe Mitral Valve Regurgitation

Canada
St. Joseph's Healthcare Hamilton
Trudell Medical International

Not yet recruiting

Effect of OPEP on Mucus Plugging and Airflow Obstruction in Patients With Moderate-to-severe Asthma (AeroMUC)

Asthma

Canada
Pan Xiangbin

Recruiting

A Prospective, Multicenter, Single-arm Study to Evaluate a Transcatheter Aortic Valve System Safety and Efficacy for the Treatment of Patients With Severe Aortic Stenosis

Severe Aortic Stenosis

China
University of Göttingen

Recruiting

Exercise CMR in (p)LF-LG AS

Aortic Stenosis, Severe

Germany
IRCCS San Raffaele

Not yet recruiting

Monocentric Retrospective Observational Study for Validation of Meta-analysis of the Metatrascryptome and Transcriptome of Eosynophyl Esophagitis

Eosinophilic Esophagitis

Italy
National and Kapodistrian University of Athens

Recruiting

Mepolizumab Effectiveness in Patients With Chronic Rhinosinusitis, Nasal Polyps and Comorbid Severe Eosinophilic Asthma (MepoRiNaPAs)

Chronic Rhinosinusitis With Nasal Polyps | Chronic Rhinosinusitis Without Nasal Polyps | Severe Eosinophilic Asthma

Greece
University Hospital of Ferrara

Recruiting

Analysis of Calcium Score of Severe Aortic Stenosis in Patients With and Without Cardiac Amyloidosis (CAUSATIVE Study) (CAUSATIVE)

Aortic Stenosis, Severe | Amyloidosis Cardiac

Italy
Guy's and St Thomas' NHS Foundation Trust
King's College London

Not yet recruiting

Outcome Prediction in Patients With Aortic Stenosis After TAVI (PREDICT-TAVI)

Aortic Stenosis, Severe

United Kingdom
GlaxoSmithKline

Not yet recruiting

REIMAGINE - Real World EvaluatIon of Mepolizumab in Severe Asthma achievinG on Treatment clinIcal remissioN, a prospEctive Study (REIMAGINE)

Asthma
Jordan Collaborating Cardiology Group

Not yet recruiting

Prevalence of ATTR Cardiac Amyloidosis in Patients Undergoing TAVR

Aortic Valve Stenosis | Severe Aortic Stenosis | ATTR Amyloidosis Wild Type | Middle East Studies
Advagene Biopharma Co. Ltd.
Taipei Medical University Hospital

Recruiting

AD17002 Treating Poorly Controlled, Moderate to Severe Eosinophilic Asthma

Eosinophilic Asthma

Taiwan
Ceric Sàrl
European Cardiovascular Research Center; Biosensors International

Not yet recruiting

All Women Comparing Self-expanding ALLEGRA Valve to Any Other Balloon-expandable Valve

Aortic Stenosis, Severe
Ibrahim Talal Elshamy

Recruiting

Endoscopic Frontal Sinus Surgery Draf III in Moderate to Severe Eosinophilic Chronic Rhinosinusitis With Polyps

Chronic Rhinosinusitis With Nasal Polyps | Endoscopic Frontal Sinus Surgery | Draf III | Draf I or IIa

Egypt
Valve Medical

Recruiting

FIH Study of the GEMINUS TAVI System in Patients With Severe Symptomatic Aortic Stenosis

Aortic Valve Stenosis

Israel
Protembis GmbH

Recruiting

The PROTEMBO Trial

Severe Aortic Valve Stenosis

United States
Heinrich-Heine University, Duesseldorf
German Research Foundation; University Bonn; University Cologne; Collaborative...

Not yet recruiting

Biomarkers and Mechanisms of Disease Progression and Outcome of Aortic Stenosis in Humans

Disease Progression | Aortic Stenosis | Genetics | Pathogenesis | Aortic Valve Calcification | Imaging

Germany
Ceric Sàrl
European Cardiovascular Research Center

Not yet recruiting

The Use of ACURATE Neo 2 Valve in Patients With Symptomatic Aortic Valve Stenosis (BSC07)

Severe Aortic Valve Stenosis

Lebanon, Saudi Arabia, Egypt
Areteia Therapeutics

Recruiting

A Study to Assess the Effect of Dexpramipexole in Adolescents and Adults With Severe Eosinophilic Asthma (EXHALE-3) (EXHALE-3)

Asthma | Eosinophilic Asthma | Asthma; Eosinophilic

United States, South Africa, United Kingdom, Korea, Republic of
NVT GmbH

Recruiting

Investigation of the NVT ALLEGRA Plus THV System in Patients With Severe Aortic Stenosis or Failed Surgical Aortic Bioprosthesis (EMPIRE-II)

Transcatheter Aortic Valve Implantation

Finland, Spain, Germany, Poland, Switzerland
IRCCS Policlinico S. Donato

Recruiting

OUTcomes Evaluation of Current Therapeutic STrategies for Severe Aortic Valve steNosis anD the agING Population in ITALY (OUTSTANDING)

Aortic Valve Stenosis

Italy
Areteia Therapeutics

Recruiting

A Study to Assess the Effect of Dexpramipexole in Adolescents and Adults With Severe Eosinophilic Asthma. (EXHALE-2)

Asthma | Eosinophilic Asthma | Asthma; Eosinophilic

United States, United Kingdom, Georgia, Romania, Brazil, Bulgaria, Korea, Republic of, Poland, Serbia, Argentina
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Severe Eosinophilic Asthma Phenotypes During Childhood Have Various Origins (SAMP 2)

Asthma in Children | Severe Asthma

France
Azienda Usl di Bologna
Università degli Studi di Ferrara; University Hospital of Ferrara; Azienda Unità...

Recruiting

TRanscatheter Aortic-Valve Implantation With or Without On-site Cardiac Surgery: the TRACS Trial (TRACS)

Aortic Stenosis, Severe

Italy
Sanofi
Regeneron Pharmaceuticals

Recruiting

A Study to Investigate the Efficacy and Safety of Dupilumab Therapy Compared With Placebo in Participants Aged ≥18 Years With Moderately to Severely Active Ulcerative Colitis With an Eosinophilic Phenotype (LIBERTY-UC SUCCEED (Study in UC for Clinical Efficacy Evaluation of Dupilumab))

Colitis Ulcerative

Argentina, Korea, Republic of, Mexico, United States, Canada, Chile, Japan, Puerto Rico, South Africa, Taiwan, Turkey
GCS Ramsay Santé pour l'Enseignement et la Recherche

Recruiting

Predictive Value of Pre-TAVI Infrahissian Conduction Time in the Occurrence of Complete Atrioventricular Block (TAVHIS)

Aortic Stenosis, Severe

France
AstraZeneca
Parexel

Recruiting

A Multicentre, Randomised, Double-blind, Parallel Group, Placebo-controlled, Time-to-first Asthma Exacerbation Phase III Efficacy and Safety Study of Benralizumab in Paediatric Patients With Severe Eosinophilic Asthma (DOMINICA) (DOMINICA)

Asthma

Korea, Republic of, Spain, United States, Argentina, France, Italy, Taiwan, Germany, United Kingdom, Poland, Canada
Chinese Academy of Medical Sciences, Fuwai Hospital

Not yet recruiting

A Clinical Trial of the Transcatheter Aortic Valve Implantation System With a Prospective, Multi-Center, One-Arm Approach to Evaluate the Efficacy and Safety in the Treatment of Patients With Severe Aortic Stenosis

Aortic Stenosis

China
Duk-Woo Park, MD
CardioVascular Research Foundation, Korea; Daewoong Pharmaceutical Co. LTD.

Not yet recruiting

ENAVOgliflozin Outcome Trial in Patients With Severe Aortic Stenosis After Transcatheter Aortic Valve Replacement (ENAVO-TAVR)

Aortic Valve Stenosis

Korea, Republic of
McMaster University
Sanofi

Not yet recruiting

IL-13 Blockade and Airway Autoimmunity in Asthma (IL-SAA)

Airway Auto Immunity in Asthma
Heinrich-Heine University, Duesseldorf
Edwards Lifesciences

Recruiting

VRAP-Heart - Virtual Reality Assisted Patient Empowerment for Interventions in Structural Heart Disease (VRAP-Heart)

Severe Aortic Valve Stenosis

Germany
Elsan
European Clinical Trial Experts Network; Belledonne clinic

Recruiting

Prospective Evaluation of the Quality of Life of Elderly Patients Undergoing Transfemoral Percutanous Aortic Valve Replacement (TAVI) for the Treatment of Severe Aortic Stenosis. (TAVI QdV)

Quality of Life | Aortic Valve Replacement | Transfemoral Approach

France
JenaValve Technology, Inc.

Not yet recruiting

TAVIS Registry - Trilogy Heart Valve System for Management of Patients With Aortic Valve Disease (TAVIS)

Aortic Valve Stenosis | Aortic Valve Disease | Heart Valve Diseases | Ventricular Outflow Obstruction | Constriction, Pathologic | Aortic Valve Stenosis With Insufficiency | Cardiovascular Diseases in Old Age | Aortic Stenosis, Severe | Aortic Valve Regurgitation

Germany
Sunshine Guojian Pharmaceutical (Shanghai) Co.,...

Not yet recruiting

A Phase II Study of 610 in Participants With Severe Eosinophilic Asthma

Asthma

China
Qilu Hospital of Shandong University

Not yet recruiting

Safety and Efficacy of Emergent TAVI in Patients With Severe AS

Emergencies | Aortic Valve Stenosis | Transcatheter Aortic Valve Implantation

Search clinical trials for: severe eosinophilic asthma, late-onset, fixed obstruction

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