Search clinical trials for: sirolimus

Total 1208 results

Fondazione Evidence per Attività e Ricerche Cardiovascolari...

Not yet recruiting

SPAGO: Sirolimus Paclitaxel Angiographic Gain Objective (SPAGO)

Coronary Artery Disease | Percutaneous Coronary Intervention | Coronary Artery Lesion | Stenosis Coronary
Children's National Research Institute
The Hospital for Sick Children; Ann & Robert H Lurie Children's Hospital of... and other collaborators

Recruiting

Sickle Cell Disease Transplant Using a Nonmyeloablative Approach for Patients With Anti-donor Red Cell AntibodY (SUN-RAY)

Sickle Cell Disease

United States
BrosMed Medical Co., Ltd
Chinese Academy of Medical Sciences, Fuwai Hospital

Not yet recruiting

Efficacy and Safety of Sirolimus-coated Coronary Balloon Dilatation Catheter for Coronary Small Vessels

Coronary Artery Disease
University Hospital, Toulouse

Not yet recruiting

Safety Study for the Use of Rapamycin in Children With Familial Adenomatous Polyposis (RAPA-4-PAF)

Familial Adenomatous Polyposis

France
M.D. Anderson Cancer Center
Aadi Bioscience

Not yet recruiting

A Phase I Trial of Combination Gemcitabine and Nab-Sirolimus in Advanced Leiomyosarcomas or Advanced Soft-Tissue Sarcomas With TSC2 or TSC1 Loss-of-function Mutations or Deletions

Leiomyosarcoma | Soft-tissue Sarcomas

United States
Advanced MedTech Solutions Pvt. Ltd.

Not yet recruiting

Advapro Coronary Stent System in Coronary Artery Diseased Patients. (RESTORE)

Coronary Artery Disease | Coronary Stent Implantation | De Novo Stenosis Lesion
City of Hope Medical Center
National Cancer Institute (NCI)

Not yet recruiting

225Ac-DOTA-Anti-CD38 Daratumumab Monoclonal Antibody With Fludarabine, Melphalan and Total Marrow and Lymphoid Irradiation as Conditioning Treatment for Donor Stem Cell Transplant in Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia and Myelodysplastic Syndrome

Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia | Myelodysplastic Syndrome

United States
Peking University People's Hospital

Not yet recruiting

Sirolimus+Abatacept+Mycophenolate Mofetil for Prophylaxis of aGVHD in Patients Receiving Haplo-HSCT Who Are Intolerant to Calcineurin Inhibitors

Myelodysplastic Syndromes | Acute Leukemia | Severe Aplastic Anemia
Concept Medical Inc.
Cardiovascular Research Foundation, New York

Not yet recruiting

MagicTouch™Sirolimus-Coated Balloon for Treatment of Coronary Artery Lesions in Small Vessels (MAGICAL-SV)

Cardiovascular Diseases | Coronary Artery Disease | Native Coronary Artery Stenosis
M.D. Anderson Cancer Center

Not yet recruiting

Low-Dose Sirolimus to Increase Hematopoietic Function in Patients With RUNX1 Familial Platelet Disorder

Familial Platelet Disorder | Hematopoietic

United States
Palvella Therapeutics, Inc.

Not yet recruiting

A Phase 3 Randomized, Double-Blind, Placebo-Controlled Study Evaluating Safety and Efficacy of QTORIN 3.9% Rapamycin Anhydrous Gel in the Treatment of Microcystic Lymphatic Malformations (SELVA)

Microcystic Lymphatic Malformation

United States
Tongji Hospital
Wuhan University; Wuhan Central Hospital; Wuhan Fourth Hospital

Recruiting

The Effects of Sirolimus in Patients With Dilated Cardiomyopathy Infected With Kaposi Sarcoma-associated Virus (SDCMK)

Dilated Cardiomyopathy | Kaposi's Sarcoma-Associated Herpesvirus Infection

China
Fundación EPIC

Recruiting

Plan to Evaluate Early Endothelialization of a Polymer Free Sirolimus-eluting Coronary Stent System (VIVO ISARTM) Compared With Everolimus-eluting Durable Polymer Stent (XIENCE SkypointTM) in Patients Undergoing Percutaneous Coronary Intervention.

Coronary Artery Disease

Spain
University National Heart Hospital
Meril Life Sciences Pvt. Ltd.

Recruiting

Scoring-Balloon Angioplasty and Sirolimus-Eluting Balloon Angioplasty for the Treatment of Diffuse, Small Vessel Coronary Artery Disease (SCA-DEB Study) (SCA-DEB)

Coronary Artery Disease

Bulgaria
Concept Medical Inc.

Not yet recruiting

Sirolimus Coated BALloon Versus Standard Balloon Angioplasty in The Treatment of Below The Knee Arterial Disease (MAGICAL BTK)

Arterial Disease of Legs
University of Ulm

Recruiting

Whey Protein Pre-load and Postprandial Glycemia in Pregnancy (ProGs)

Pregnancy | Postprandial Glycemia

Germany
Sohag University

Recruiting

Role of Sirolimus in Treatment of Microcystic , Mixed Lymphatic and Vascular Malformations

Vascular Malformations | Microcystic Lymphatic Malformation | Combined Vascular Malformation

Egypt
Diabetes Free, Inc.

Not yet recruiting

Tolerance to Islet Allotransplants in Diabetes

Diabetes Mellitus Type 2 - Insulin-Treated
The University of Texas Health Science Center,...

Not yet recruiting

Impact of Methadone on Prolonged Mechanical Ventilation in Patients on Continuous Treatment With Opioids (IMPACTOR)

Effect of Methadone on the Duration on Mechanical Ventilation

United States
Huashan Hospital

Not yet recruiting

Hemorrhagic Brainstem Cavernous Malformations Treatment With Sirolimus: a Single Centre, Randomised, Placebo-controlled Trial (CALM)

Cavernous Malformations | Brain Stem Hemorrhage

China
Genoss Co., Ltd.

Recruiting

Evaluation of Effectiveness and Safety of Abluminal Biodegradable Polymer Sirolimus-eluting Stent (GENCOMX)

Coronary Artery Disease | Percutaneous Coronary Intervention

Korea, Republic of
Case Comprehensive Cancer Center

Not yet recruiting

Intestinal & Multivisceral Transplantation for Unresectable Mucinous Carcinoma Peritonei (TRANSCAPE) (TRANSCAPE)

Pseudomyxoma Peritonei | Secondary Malignant Neoplasm of Peritoneum | Secondary Malignant Neoplasm of Retroperitoneum

United States
Stanford University

Not yet recruiting

Sirolimus for Improving Social Abilities in People With PTEN Germline Mutations

PTEN Gene Mutation | PTEN Hamartoma Tumor Syndrome | PTEN Hamartoma Syndrome

United States
Markus Mapara
ITB-Med LLC

Recruiting

Siplizumab for Sickle Cell Disease Transplant (CD2 SCD)

Anemia, Sickle Cell

United States
Genoss Co., Ltd.

Recruiting

Evaluating Efficacy and Safety of 1-year of DAPT After Genoss DES Sirolimus-eluting Stent Implantation in Patients (DAPTLONG)

Coronary Artery Disease | Percutaneous Coronary Intervention | Dual Antiplatelet Therapy

Korea, Republic of
R3 Vascular Inc.

Not yet recruiting

Bioresorbable Sirolimus-Eluting Scaffold Treatment for Below the Knee Disease (ELITE-BTK)

Chronic Limb-Threatening Ischemia
Genoss Co., Ltd.

Recruiting

Efficacy of OSFIT Drug-Eluting Stent in Coronary Ostial Artery Stenosis

Coronary Artery Disease | Drug-eluting Stent

Korea, Republic of
National Institute of Allergy and Infectious Diseases...

Not yet recruiting

Advancing Transplantation Outcomes in Children (ADVANTage)

Kidney Transplant

United States
Shanghai Bomaian Medical Technology Co., Ltd

Not yet recruiting

Rapamycin Coated Balloon Dilation Catheter for Arteriovenous Fistula

Peripheral Arterial Disease
Steven Hays, MD
OrphAI Therapeutics

Recruiting

LAM-001 in Lung Transplant Recipients With Bronchiolitis Obliterans Syndrome. (INSPO-BOS)

Lung Transplantation | Chronic Lung Allograft Dysfunction | Bronchiolitis Obliterans Syndrome

United States
Aadi Bioscience, Inc.

Recruiting

Trial of Nab-Sirolimus in Combination With Letrozole in Patients With Advanced or Recurrent Endometrioid Endometrial Cancer

Cancer | Endometrial Cancer | Tumor | Recurrent Endometrial Carcinoma | Endometrioid Endometrial Cancer | Endometrioid Tumor

United States
Aadi Bioscience, Inc.

Recruiting

Trial of Nab-sirolimus in Patients With Well-differentiated Neuroendocrine Tumors (NETs) of the Gastrointestinal Tract, Lung, or Pancreas Who Have Not Received Prior Treatment With mTOR Inhibitors

Neuroendocrine Tumors | Pancreatic Neuroendocrine Tumor | Gastrointestinal Neuroendocrine Tumor | NET | Pulmonary Neuroendocrine Tumor

United States
Biotyx Medical (Shenzhen) Co., Ltd.
VascuScience GmbH; Mediolanum Cardio Research Srl; Euroimage Research Srl

Recruiting

IBS Titan™ Sirolimus-eluting Iron Bioresorbable Peripheral Scaffold System Clinical Trial

Critical Limb Ischemia | Infrapopliteal Lesions

Italy
iVascular S.L.U.

Not yet recruiting

Ischemic and Bleeding Outcomes After Angiolite Stent Implantation and an Abbreviated Dual Antiplatelet Therapy (ANGIODAPT)

Coronary Artery Disease
University of Wisconsin, Madison
National Institutes of Health (NIH); National Institute on Aging (NIA)

Recruiting

Rapalog Pharmacology (RAP PAC) Study

Aging

United States
M.A. Med Alliance S.A.

Recruiting

SELUTION 4 De Novo Small Vessel IDE Trial

Coronary Artery Disease

United States
Singapore General Hospital
National Medical Research Council (NMRC), Singapore

Recruiting

Sirolimus Drug-coated Balloon Versus Stent Graft (SUSTAIN)

Blood Vessel Prosthesis | Arteriovenous Shunt Thrombosis

Singapore
Peking Union Medical College Hospital

Recruiting

Sirolimus in the Treatment of Refractory/Relapsed wAIHA

Warm Autoimmune Hemolytic Anemia

China
Xue-chun Lu

Recruiting

Combination Regimen With Sodium Valproate for Severe Hemophilia: a Single-arm, Phase 1, Pilot Trial.

Hemophilia

China
Wrightington, Wigan and Leigh NHS Foundation Trust
Professor Azfar Zaman - Freeman Hospital, Newcastle

Recruiting

Large De-NOVo Coronary artEry Disease Treated With Sirolimus Drug Eluting Balloon (LOVE DEB)

Coronary Artery Disease

United Kingdom
Concept Medical Inc.
Cardiovascular Research Foundation, New York

Not yet recruiting

MagicTouch for Treatment of In-Stent Restenosis in Coronary Artery Lesions (MAGICAL ISR)

Cardiovascular Diseases | Coronary Artery Disease | In-Stent Restenosis

United States
National Cancer Institute (NCI)

Recruiting

Immunotherapy in Combination With Prednisone and Sirolimus for Kidney Transplant Recipients With Unresectable or Metastatic Skin Cancer

Metastatic Melanoma | Unresectable Melanoma | Clinical Stage III Cutaneous Melanoma AJCC v8 | Metastatic Merkel Cell Carcinoma | Metastatic Skin Squamous Cell Carcinoma | Clinical Stage IV Cutaneous Melanoma AJCC v8 | Metastatic Basal Cell Carcinoma | Unresectable Merkel Cell Carcinoma | Unresectable... and other conditions

United States
Xuanwu Hospital, Beijing

Recruiting

Drug-eluting Stenting Versus Medical Treatment for Extracranial Vertebral Artery Stenosis (VISTA)

Ischemic Stroke | Vertebral Artery Stenosis

China
Melanoma and Skin Cancer Trials Limited
Monash University; The University of Queensland

Not yet recruiting

Topical Sirolimus in Chemoprevention of Facial Squamous Cell Carcinomas in Solid Organ Transplant Recipients (SiroSkin) (SiroSkin)

Skin Cancer | Solid Organ Transplant Recipients

Australia
Mirati Therapeutics Inc.
Aadi Bioscience, Inc.

Recruiting

Adagrasib in Combination With Nab-Sirolimus in Patients With Advanced Solid Tumors and Non-Small Cell Lung Cancer With a KRAS G12C Mutation (KRYSTAL -19)

NSCLC | Metastatic Cancer | Advanced Cancer | Solid Tumor, Adult | Malignant Neoplastic Disease

United States
Columbia University

Recruiting

Effect of Rapamycin in Ovarian Aging (Rapamycin)

Perimenopausal

United States
University of Miami

Recruiting

Levels of Circulating Tumor DNA as a Predictive Marker for Early Switch in Treatment for Patients With Metastatic (Stage IV) Breast Cancer

Breast Cancer | Metastatic Breast Cancer | ER-positive Breast Cancer | HER2-negative Breast Cancer

United States
Masonic Cancer Center, University of Minnesota

Recruiting

Allo HSCT Using RIC and PTCy for Hematological Diseases

Follicular Lymphoma | Myelodysplastic Syndromes | Leukemia, Myeloid | Myelofibrosis | Burkitt Lymphoma | Marginal Zone Lymphoma | Acute Lymphocytic Leukemia | Acute Myelogenous Leukemia | Chronic Myelogenous Leukemia | Prolymphocytic Leukemia | Plasma Cell Leukemia | Myeloproliferative Neoplasm | Small Lymphocytic... and other conditions

United States
Hospital Universitario La Fe

Recruiting

Cutting Balloon Predilation Prior to Abluminus Sirolimus-eluting Stent Implantation (CUT-DRESS). (CUT-DRESS)

Coronary Artery Disease | Percutaneous Coronary Intervention | Cutting Balloon

Spain
IGLESIAS Juan Fernando
Clinical Trials Unit University of Bern

Not yet recruiting

STEMI Treated With a Polymer-free Sirolimus-coated Stent and P2Y12 Inhibitor-based SAPT Versus Conventional DAPT (STARS DAPT)

ST Elevation Myocardial Infarction

Switzerland

Search clinical trials for: sirolimus

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