Search clinical trials for: standard of care in IDH1 mutant acute myeloid leukemia
Total 488069 results
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Duke UniversityEunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaboratorsRecruitingHeart Failure | Pain | Pneumonia | Hypertension | Edema | Hemophilia | Insomnia | Pulmonary Arterial Hypertension | Coagulation Disorder | Asthma in Children | Down Syndrome | Attention Deficit Hyperactivity Disorder | Bronchopulmonary Dysplasia | Hypokalemia | Hyperphosphatemia | Primary Hyperaldosteronism | Adrenal Insufficiency and other conditionsUnited States, Canada
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NewLink Genetics CorporationCompletedAcute Myeloid LeukemiaUnited States
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Forma Therapeutics, Inc.CompletedAcute Myeloid Leukemia | Myelodysplastic Syndrome | Acute Myelogenous LeukemiaUnited States, Spain, Korea, Republic of, Australia, Canada, Germany, France, United Kingdom, Italy
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University College DublinRush University Medical Center; Royal College of Surgeons, Ireland; Mater Misericordiae... and other collaboratorsTerminatedBone DemineralizationIreland
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Servier Affaires MédicalesRecruitingAcute Myeloid Leukemia (AML)Netherlands, Italy, Austria, France
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Eli Lilly and CompanyLoxo Oncology, Inc.Active, not recruitingAcute Myeloid Leukemia (AML) | Chronic Myelomonocytic Leukemia (CMML) | Myelodysplastic Syndrome (MDS) | Myeloproliferative Neoplasms (MPNs)United States, Spain, Korea, Republic of, France, Taiwan, Australia, Belgium, Singapore, Israel, Canada, Germany, Finland
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National Taiwan University HospitalUnknownAcute Myeloid LeukemiaTaiwan
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Institut de Recherches Internationales ServierRecruitingMyelodysplastic Syndromes | Relapsed or Refractory Acute Myeloid Leukemia (AML) | Untreated AML | Other IDH1-mutated Positive Hematologic MalignanciesUnited States, France
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Aptose Biosciences Inc.Active, not recruitingAcute Myeloid Leukemia | Myelodysplastic SyndromesUnited States
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Agios Pharmaceuticals, Inc.CompletedMyelodysplastic Syndrome | Hematologic Malignancies | Acute Myeloid Leukemia (AML)United States, France
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Novartis PharmaceuticalsActive, not recruitingAdvanced Malignancies That Harbor IDHR132 MutationsBelgium, Germany, Spain, Canada, Australia, United States, Netherlands, Singapore
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Institut de Recherches Internationales ServierCelgene CorporationActive, not recruitingUntreated AML | Newly Diagnosed Acute Myeloid Leukemia (AML) | AML Arising From Myelodysplastic Syndrome (MDS) | AML Arising From Antecedent Hematologic Disorder (AHD) | AML Arising After Exposure to Genotoxic InjuryUnited States, Germany, Netherlands
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Massachusetts General HospitalAgios Pharmaceuticals, Inc.CompletedIDH1 Mutation Myeloid NeoplasmsUnited States
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Groupe Francophone des MyelodysplasiesActive, not recruitingAcute Myeloid Leukemia | Myelodysplastic SyndromesFrance, Italy
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iOMEDICO AGRecruitingAcute Myeloid Leukemia (AML)Germany
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Rigel PharmaceuticalsNationwide Children's HospitalNot yet recruitingAstrocytoma | High Grade Glioma | Oligodendroglioma | Diffuse Intrinsic Pontine Glioma | Diffuse Midline Glioma, H3 K27M-Mutant | WHO Grade III Glioma | Metastatic Brain Tumor | Spinal Tumor | Astrocytoma, Grade III | Astrocytoma, Grade IV | IDH1 Mutation | WHO Grade IV Glioma | Thalamus Tumor | IDH1 R132 | IDH1 R132C | IDH1 R132H and other conditionsUnited States, Australia, United Kingdom, Canada, Germany, Netherlands
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Mingge LLCFudan University; Huashan HospitalActive, not recruitingGlioma, Malignant | Computer-AssistedChina
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Institut de Recherches Internationales ServierCompletedMetastatic Cholangiocarcinoma | Advanced CholangiocarcinomaUnited States, Spain, Korea, Republic of, Italy, France, United Kingdom
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Hospital General de MexicoUnknown
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AnHeart Therapeutics Inc.RecruitingIDH1 Inhibitor AB-218 in Patients With Advanced IDH1 Mutant Cholangiocarcinoma and Other Solid TumorCholangiocarcinoma With IDH1 Mutation | Solid Tumors With IDH1 MutationChina
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BayerActive, not recruitingSolid TumorsUnited States, Germany, Japan, Denmark
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BayerCompletedLeukemia, Myeloid, AcuteUnited States, Germany
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Daiichi Sankyo Co., Ltd.Active, not recruiting
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NYU Langone HealthNovartisWithdrawn
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Hebei Yanda HospitalBeijing Tiantan HospitalUnknown
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Regina Elena Cancer InstituteUniversity of Roma La Sapienza; Fondazione I.R.C.C.S. Istituto Neurologico... and other collaboratorsActive, not recruiting
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National Center for Tumor Diseases, HeidelbergGerman Cancer Research Center; University Hospital Heidelberg; Neuro-Oncology...Completed
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Servier Bio-Innovation LLCInstitut de Recherches Internationales ServierNot yet recruitingLocally Advanced or Metastatic Conventional Chondrosarcoma With an IDH1 Mutation, Untreated or Previously Treated With 1 Systemic Treatment Regimen
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Melbourne HealthAnHeart Therapeutics Inc.; Walter and Eliza Hall Institute of Medical ResearchActive, not recruiting
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Xennials Therapeutics Australia Pty LtdPinotbio, Inc.TerminatedAdvanced Solid Tumor | High-grade Glioma | Platinum-Resistant Ovarian Cancer | Platinum-Resistant Urothelial CarcinomaAustralia
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Istituto Clinico HumanitasCelgeneUnknownAcute Myeloid Leukemia | IDH2 Gene Mutation | IDH1 Gene MutationItaly
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Institut de Recherches Internationales ServierCompletedGlioma | Cholangiocarcinoma | Chondrosarcoma | Other Advanced Solid TumorsUnited States, France
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Eli Lilly and CompanyLoxo Oncology, Inc.Active, not recruitingGlioma | Cholangiocarcinoma | Chondrosarcoma | Any Solid TumorUnited States, Spain, Korea, Republic of, Australia, Japan, Taiwan, France, Singapore, Hong Kong
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Novartis PharmaceuticalsWithdrawnAcute Myeloid Leukemia (AML)
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Institut de Recherches Internationales ServierActive, not recruiting
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Institut de Recherches Internationales ServierActive, not recruiting
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Institut National de la Santé Et de la Recherche...CompletedNon Invasive Diagnosis of GliomaFrance
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Memorial Sloan Kettering Cancer CenterAstellas Pharma US, Inc.RecruitingAcute Myeloid Leukemia (AML)United States
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Assistance Publique - Hôpitaux de ParisActive, not recruitingRecurrent IDH1/2 Mutated GliomaFrance
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Agios Pharmaceuticals, Inc.Approved for marketingAcute Myeloid Leukemia | Relapsed Pediatric AML | Relapsed Adult AML
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Servier Bio-Innovation LLCInstitut de Recherches Internationales ServierRecruitingIDH1-mutant CholangiocarcinomaUnited States, United Kingdom
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Yale UniversityWithdrawnAcute Myeloid Leukemia | Myelodysplastic SyndromesUnited States
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Northwestern UniversityNational Cancer Institute (NCI)RecruitingRecurrent Acute Myeloid Leukemia | Recurrent Myelodysplastic Syndrome | Refractory Acute Myeloid Leukemia | Refractory Myelodysplastic Syndrome | Recurrent Myeloproliferative NeoplasmUnited States
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University of ChicagoRecruitingMyeloproliferative Neoplasm | Blood Cancer | IDH2 Gene Mutation | IDH1 Mutation | IDH MutationUnited States
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CStone PharmaceuticalsCompletedRelapsed or Refractory Acute Myeloid LeukemiaChina
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Jason J. Luke, MDBristol-Myers Squibb; Agios Pharmaceuticals, Inc.CompletedGlioma | Advanced Solid Tumor | IDH1 MutationUnited States
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AnHeart Therapeutics Inc.Recruiting
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National Cancer Institute (NCI)SuspendedMalignant Solid Neoplasm | Refractory Malignant Solid Neoplasm | Refractory CholangiocarcinomaUnited States
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Vanderbilt-Ingram Cancer CenterAstex Pharmaceuticals, Inc.; Forma Therapeutics, Inc.WithdrawnAcute Myeloid Leukemia | Myelodysplastic Syndrome | Recurrent Acute Myeloid Leukemia | Recurrent Myelodysplastic Syndrome | Refractory Acute Myeloid Leukemia | Refractory Myelodysplastic Syndrome
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M.D. Anderson Cancer CenterRecruitingAcute Myeloid Leukemia | Myelodysplastic Syndrome | Recurrent Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia | Hematopoietic and Lymphoid System Neoplasm | Myeloproliferative NeoplasmUnited States