Search clinical trials for: standard therapy exists

Total 62738 results

City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

RNR Inhibitor COH29 in Treating Patients With Solid Tumors That Are Refractory to Standard Therapy or For Which No Standard Therapy Exists

Unspecified Adult Solid Tumor, Protocol Specific

United States
Abramson Cancer Center of the University of Pennsylvania

Completed

Phase 1, Open-Label, Dose-Escalation Study of CP-870,893 in Patients With Solid Tumors

Advanced Solid Tumors

United States
Taiho Oncology, Inc.

Completed

Study Comparing the Pharmacokinetics of FTD as a Component of TAS-102 With FTD Alone

Advanced Solid Tumors

United States
Genentech, Inc.

Completed

A Study of Hedgehog Pathway Inhibitor GDC-0449 in Patients With Locally Advanced or Metastatic Solid Tumors That Are Refractory to Standard Therapy or for Whom No Standard Therapy Exists

Solid Cancers
Taiho Oncology, Inc.

Completed

Study Comparing the Bioavailability of TAS-102 Tablets to an Oral Solution Containing Equivalent Amounts of FTD and TPI

Advanced Solid Tumors (Excluding Breast Cancer)

United States
Taiho Oncology, Inc.

Completed

Study to Evaluate the Cardiac Safety of TAS-102 in Patients With Advanced Solid Tumors

Advanced Solid Tumors (Excluding Breast Cancer)

United States
Genentech, Inc.

Completed

A Study of Pharmacokinetic Drug Interaction Study of the Hedgehog Pathway Inhibitor GDC-0449 in Combination With Rosiglitazone or Combined Oral Contraceptive in Patients With Locally Advanced or Metastatic Solid Tumors That Are Refractory to Standard Therapy or for Whom No Standard Therapy Exists

Solid Cancers

United States
Synta Pharmaceuticals Corp.

Completed

Study of STA-9090, Administered Once-Weekly in Patients With Solid Tumors

Solid Tumors

United States
Bristol-Myers Squibb

Completed

Study of Dasatinib (BMS-354825) in Patients With Solid Tumors

Tumors

Japan
Mayo Clinic

Not yet recruiting

Pleural Space Saline Irrigation in Addition to Standard Intrapleural Thrombolytic Therapy in Empyema/Complicated Parapneumonic Effusion

Pleural Infection

United States
Rijnstate Hospital

Recruiting

Comparison of Apnea-Hypopnea Index in Patients With or Without Preventive Oxygen Therapy After Bariatric Surgery (OXYBAR)

Obesity | Obstructive Sleep Apnea | Bariatric Surgery Candidate

Netherlands
Baylor Research Institute
National Institute on Disability, Independent Living, and Rehabilitation...

Recruiting

Early Robotic Gait Training After Stroke (ERA Stroke)

Stroke

United States
University of Hail

Not yet recruiting

Decompression Versus Heat and Decompression in Knee OA

Knee Osteoarthritis

Saudi Arabia
Boston Medical Group

Recruiting

Effectiveness and Safety of TENS Therapy for Premature Ejaculation (TENSPE2)

Premature Ejaculation | TEN | Sex Disorder

Mexico
University of Southern California
National Cancer Institute (NCI)

Not yet recruiting

Access to Genetic Testing in Underserved Patients With Cancer

Malignant Solid Neoplasm | Breast Carcinoma | Metastatic Prostate Carcinoma | Ovarian Carcinoma | Triple-Negative Breast Carcinoma | Male Breast Carcinoma | Pancreatic Exocrine Neoplasm | Stage IVB Prostate Cancer American Joint Committee on Cancer v8

United States
Emory University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Not yet recruiting

Automated Insulin Delivery for Inpatients With Dysglycemia (AIDING)

Type 1 Diabetes | Type 2 Diabetes

United States
Kite, A Gilead Company
Arcellx, Inc.

Not yet recruiting

A Study Comparing Anitocabtagene Autoleucel to Standard of Care Therapy in Participants With Relapsed/ Refractory Multiple Myeloma (iMMagine-3)

Multiple Myeloma
Dokuz Eylul University

Not yet recruiting

Effects of Corrective External Support and Regional Vibration Applications in Subacromial Pain Syndrome

Subacromial Pain Syndrome
Shanghai Changzheng Hospital

Recruiting

UCMSCs Combined With Standard Therapy for the Treatment of Newly Diagnosed Type 1 Diabetes

Newly Diagnosed Type 1 Diabetes Mellitus

China
Johns Hopkins University

Recruiting

Using Personalized Assessments in the Treatment of Childhood OCD

Obsessive-Compulsive Disorder

United States
Kyverna Therapeutics

Not yet recruiting

A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell (CD19 CAR T) Therapy, in Subjects With Systemic Sclerosis

Systemic Sclerosis | Systemic Sclerosis - Diffuse Cutaneous | Systemic Sclerosis - 2013 ACR/EULAR Classification Criteria
Janjira Petsuksiri
Mahidol University

Not yet recruiting

Orbital Radiotherapy in Grave's Ophthalmopathy 1 Week vs 2 Weeks (OraGO-1 Trial)

Thyroid Associated Ophthalmopathy

Thailand
Ohio State University Comprehensive Cancer Center

Not yet recruiting

Ketogenic Dietary Intervention to Improve Response to Immunotherapy in Patients With Metastatic Melanoma and Metastatic Kidney Cancer

Metastatic Renal Cell Carcinoma | Metastatic Cutaneous Melanoma | Stage IV Renal Cell Cancer AJCC v8 | Clinical Stage IV Cutaneous Melanoma AJCC v8

United States
The Affiliated Nanjing Drum Tower Hospital of Nanjing...

Not yet recruiting

Immunosensitized Radiotherapy Combined With Evoximab (AK112) and Chemotherapy Neoadjuvant Therapy for Stage II-III Non-small Cell Lung Cancer

Stereotactic Radiotherapy; Evoximab (AK112); New Adjuvant Therapy for Non-small Cell Lung Cancer
Genmab
BioNTech SE

Recruiting

Trial to Assess the Safety and Preliminary Efficacy of GEN1055 on Malignant Solid Tumors as Monotherapy and as Combination Therapy

Malignant Solid Tumor

Spain
Yang Jianjun, PhD

Not yet recruiting

Serplulimab Combined With Nab-paclitaxel and Cisplatin in Neoadjuvant Therapy for Resectable Esophageal Squamous Cell Carcinoma

Esophageal Squamous Cell Carcinoma
Kyverna Therapeutics

Not yet recruiting

A Study of Anti-CD19 CAR T-Cell Therapy, in Subjects With Refractory Primary and Secondary Progressive Multiple Sclerosis

Multiple Sclerosis | Multiple Sclerosis, Secondary Progressive | Multiple Sclerosis, Primary Progressive
University Hospital, Basel, Switzerland

Not yet recruiting

Validation of New Diagnostic Indices to Simplify Hyponatremia Therapy Assessment in Patients on Thiazide Diuretics

Thiazide Associated Hyponatremia

Switzerland
Lyvgen Biopharma Holdings Limited

Not yet recruiting

A Study of LVGN6051 Combination Therapy in Patient With Head and Neck Squamous Cell Carcinoma (HNSCC)

Head and Neck Squamous Cell Carcinoma

China
Mayo Clinic

Not yet recruiting

Remote Cognitive Assessment Battery and Wearable Device Monitoring Platform While Assessing the Impact of Metformin in Patients With History of Cranial Radiation Therapy

Malignant Brain Neoplasm

United States
Jonsson Comprehensive Cancer Center
National Cancer Institute (NCI)

Not yet recruiting

Improving Colonoscopy Surveillance for Patients With High Risk Colon Polyps

Colorectal Carcinoma

United States
Cancer Institute and Hospital, Chinese Academy...

Recruiting

Neo-Sequence 2：NCT Plus Anti-angiogenesis Therapy and Immunotherapy for LADGC

Gastric Cancer | Diffuse Type Carcinoma

China
Sun Yat-sen University
Kousai Bio Co., Ltd.

Not yet recruiting

KSD-101 Therapy for Standard Treatment Failed EBV-associated NPC: an Exploratory Clinical Trial

Nasopharyngeal Carcinoma

China
Health Science Center of Xi'an Jiaotong University
Huazhong University of Science and Technology; LinkDoc Technology (Beijing)...

Recruiting

The Study of Huaier Granule in Postoperative Adjuvant Therapy of Resectable Pancreatic Cancer

Pancreatic Cancer Resectable

China
University of Erlangen-Nürnberg Medical School

Not yet recruiting

App-based Recording and Optimization of the Nutritional Status in Patients With Head and Neck Tumors During and After Radio(Chemo)Therapy

Squamous Cell Carcinoma of Head and Neck

Germany
Stanford University
National Institute of Mental Health (NIMH); MainSquare Co. (dba 'Teleo')

Not yet recruiting

Engagement and Clinical Impact of the Teleo Virtual Therapy Platform in Clinical Settings - Pilot RCT

Mood Disorders | Anxiety Disorders

United States
Schulthess Klinik

Not yet recruiting

Postoperative Pain After Implementation of Standardized Pain Therapy Management in Orthopaedic Patients (PAIN)

Postoperative Pain, Acute
Sun Jing

Not yet recruiting

A Clinical Study on the Efficacy and Safety of Paclitaxel Polymer Micelles and Cisplatin Combined With Cadonilimab as a Neoadjuvant Therapy for Locally Advanced Esophageal Squamous Cell Carcinoma

Neoadjuvant Therapy | Locally Advanced Esophageal Squamous Cell Carcinoma
University of Pittsburgh
American College of Radiation Oncology

Not yet recruiting

Liver Volume Variation Effect on SBRT Planning and Delivery for Upper Abdominal Malignancies

Upper Abdominal Malignancies

United States
Institute of Liver and Biliary Sciences, India

Not yet recruiting

Efficacy of Plasma Exchange Therapy vs Standard Medical Therapy in Severe Alcoholic Hepatitis With High Discriminant Function

Alcoholic Hepatitis

India
SHUANGZHENGJIA

Recruiting

The Effects of Immunonutrition Therapy on Locally Advanced Cervical Cancer Patients

Cervical Cancers

China
Zhejiang Cancer Hospital

Recruiting

A Randomized, Multicenter Phase II Basket Study of Hypofractionated Radiotherapy/Stereotactic Body Radiotherapy Followed by Immunotherapy-Based Systemic Therapy +/- L. Rhamnosus M9 for the First-Line Treatment of Advanced Digestive System Malignancies.

Gastric Cancer | Colorectal Cancer | Pancreatic Adenocarcinoma | Biliary Tract Cancer | Gastroesophageal Junction Adenocarcinoma | Liver Cancer Stage IV

China
Kaohsiung Medical University

Recruiting

Efficacies of Bismuth-amoxicillin-vonoprazan Triple Therapy, Vonoprazan-amoxicillin Dual Therapy and Proton Pump Inhibitor-based Standard Triple Therapy for Hp Eradication

Helicobacter Pylori Eradication

Taiwan
Kyverna Therapeutics

Recruiting

A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell (CD19 CAR T) Therapy, in Subjects With Refractory Lupus Nephritis (KYSA-3)

Lupus Nephritis | Lupus Nephritis - WHO Class IV | Lupus Nephritis - WHO Class III

Germany
Clexio Biosciences Ltd.

Recruiting

A Study of CLE-100 (Oral Esketamine) as an Adjunctive Treatment to Standard Antidepressants for Major Depressive Disorder (SOLEO)

Adjunctive Treatment of Major Depressive Disorder (MDD)

United States
Eli Lilly and Company

Recruiting

A Study of Lebrikizumab (LY3650150) in Adult Participants With Chronic Rhinosinusitis and Nasal Polyps Treated With Intranasal Corticosteroids (CONTRAST-NP)

Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)

Belgium, Italy, United States, Bulgaria
Shenyang Northern Hospital

Not yet recruiting

OCT or Angiography Guided De-escalation of DAPT

ST Elevation Myocardial Infarction | Dual Antiplatelet Therapy | Optical Coherence Tomography | Antiplatelet De-escalation | Neointimal Coverage

China
Eli Lilly and Company

Recruiting

A Study of Lebrikizumab in Adult Participants With Perennial Allergic Rhinitis (PREPARED-1)

Perennial Allergic Rhinitis (PAR)

United States
Guangdong Ruishun Biotech Co., Ltd
Changhai Hospital; Peking University People's Hospital; RenJi Hospital; The Affiliated...

Not yet recruiting

A Study of RJMty19 in Refractory Systemic Lupus Erythematosus (SLE)

Systemic Lupus Erythematosus

China
M.D. Anderson Cancer Center

Recruiting

STRICT - Surveillance With TRoponin During Immune Checkpoint Therapy

Immune Checkpoint Therapy

United States

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