Search clinical trials for: systemic therapies

Total 8551 results

Erasmus Medical Center
Tata Memorial Centre

Not yet recruiting

Retrospective Cervical Cancer Oligo States (Recurrence, Metastasis) Multicentre Outcomes Study (Retro-COSMOS)

Recurrence | Metastasis | Cancer, Cervical
University of Southern Denmark
Hospital of South West Jutland

Not yet recruiting

Comparison of Three Different Antibiotic Treatments Against Recurrent Urinary Tract Infections in Catheterized Patients

Recurrent Urinary Tract Infections | Antibiotic Treatment | Chronic Urinary-catheter-carrier | Biofilm Infection | Replacement of Urinary Catheter
University Hospital, Toulouse

Recruiting

Clinico-biological Collection to Investigate the Physiopathology of Systemic Autoimmune Diseases (ESSAi)

Inflammatory Bowel Diseases | Vasculitis | Myositis | Lupus Erythematosus | Scleroderma

France
Swiss Group for Clinical Cancer Research
Immunophotonics, Inc.

Recruiting

Intratumoral Injection of IP-001 Following Thermal Ablation in Patients With Advanced Solid Tumors.

Advanced Solid Tumors

Switzerland
Academisch Medisch Centrum - Universiteit van Amsterdam...

Recruiting

TREAT NL (TREatment of ATopic Eczema, the Netherlands) Registry: Dutch National Registry for Patients With Moderate-to-severe Atopic Eczema on Photo- or Systemic Therapies (TREAT NL)

Moderate-to-severe Atopic Eczema

Netherlands
Second Affiliated Hospital of Guangzhou Medical...

Recruiting

CRRT Timing in Sepsis-associated AKI in ICU (CRTSAKI)

RTT | Sepsis-Associated Organ Dysfunction

China
Swiss Dermatology Network for Targeted Therapies

Recruiting

Swiss Dermatology Network of Targeted Therapies (SDNTT) (SDNTT)

Psoriasis

Switzerland
Amgen

Completed

Efficacy and Safety of AMG 570 in Subjects With Active Systemic Lupus Erythematosus (SLE)

Systemic Lupus Erythematosus (SLE)

United States, Korea, Republic of, Australia, Spain, Hungary, Bulgaria, Italy, Mexico, Germany, Japan, France, Greece, Czechia, Argentina, Portugal, Poland, Russian Federation, Hong Kong, Canada
Sidney Kimmel Comprehensive Cancer Center at Johns...
Bristol-Myers Squibb

Active, not recruiting

REACTION (Radiation Enhanced Assessment of Combination Therapies in Immuno-ONcology) - Nivolumab or Nivolumab in Combination With Other Immuno-oncology (IO) Agents After Targeted Systemic Radiation in Patients With Advanced Esophagogastric Cancer (REACTION)

Gastroesophageal Cancer | Immune Checkpoint Inhibition

United States
First Affiliated Hospital of Wenzhou Medical University
Qilu Hospital of Shandong University; Eastern Hepatobiliary Surgery Hospital; The First Affiliated Hospital of Zhejiang Chinese Medical University

Enrolling by invitation

Effect of Sarcopenia on Hepatocellular Carcinoma(HCC) After Systemic Therapies

Hepatocellular Carcinoma | Sarcopenia

China
First Affiliated Hospital of Wenzhou Medical University
Qilu Hospital of Shandong University; Eastern Hepatobiliary Surgery Hospital; The First Affiliated Hospital of Zhejiang Chinese Medical University

Enrolling by invitation

Predicting Response to Systemic Therapies for Hepatocellular Carcinoma(HCC)

Hepatocellular Carcinoma Non-resectable | Effect of Drug

China
Assiut University

Active, not recruiting

Reappraisal of the Therapies of Refractory Autoimmune Hemolytic Anemia in Systemic Lupus Erythematosus

Systemic Lupus Erythematosus | Autoimmune Hemolytic Anemia

Egypt
Centre Leon Berard

Terminated

Efficacy and Safety of Systemic Treatments of Bone Metastases From Kidney Cancer in Patients Treated With Targeted Therapies (MOSCAR)

Metastatic Renal Cell Carcinoma

France
MorphoSys AG

Completed

Observational Retrospective Cohort Study of Systemic Therapies for R/R DLBCL (RE-MIND2)

Diffuse Large B Cell Lymphoma

France, Italy, Spain, United States, Austria, Australia, Germany, Korea, Republic of, Canada, Denmark, Taiwan, United Kingdom
Fundación Pública Andaluza Progreso y Salud
Karolinska Institutet; Eli Lilly and Company; Medical University of Vienna; Sanofi and other collaborators

Completed

Molecular Reclassification to Find Clinically Useful Biomarkers for Systemic Autoimmune Diseases: Inception Cohort (PRECISESADSI)

Systemic Autoimmune Diseases

France, Belgium, Germany, Italy, Spain, Switzerland
Phoenicis Therapeutics

Terminated

A Double-blind, Randomized, Intra-subject Placebo-controlled, Multicenter, Multiple Dose Study, Evaluating Safety, Proof of Mechanism, Preliminary Efficacy and Systemic Exposure in Subjects With Confirmed DDEB or RDEB Diagnosis With One or More Pathogenic Mutations in Exon 73 in the COL7A1 Gene

Epidermolysis Bullosa Dystrophica, Recessive | Epidermolysis Bullosa Dystrophica, Dominant

United States, Spain, France
Institut de Cancérologie de la Loire

Terminated

Geriatric Intervention Contribution on Quality of Life of Elderly Patients With Metastatic Neoplasia (QUALI)

Elderly Patients | Systemic Treatment | Metastatic Neoplasia

France
Andalusian Initiative for Advanced Therapies -...
Iniciativa Andaluza en Terapias Avanzadas

Completed

Treatment With MSC in HIV-infected Patients With Controlled Viremia and Immunological Discordant Response

Discordant Immunological Response in HIV Infected Subjects

Spain
Institut de Cancérologie de la Loire
Saint-Louis Hospital, Paris, France; Gustave Roussy, Cancer Campus, Grand Paris

Withdrawn

Phase II Trial Assessing the Efficacy of Immuno-Radiation Abscopal Effect in Patients With Metastatic Cancers (IRAM)

Metastatic Colorectal Cancer | Metastatic Breast Cancer | Metastatic Head and Neck Cancer

France
Hospital Universitari de Bellvitge
Hospital de Sant Pau

Completed

Impact of CVVHD With Adsorption Capacity Membranes in Septic Acute Kidney Injury

Sepsis | Septic Shock | Acute Kidney Injury

Spain
Fundación Pública Andaluza Progreso y Salud
Karolinska Institutet; Eli Lilly and Company; Medical University of Vienna; Sanofi and other collaborators

Completed

Molecular Reclassification to Find Clinically Useful Biomarkers for Systemic Autoimmune Diseases: (PRECISESADS)

Systemic Autoimmune Diseases

France, Germany, Austria, Portugal, Hungary, Belgium, Italy, Spain, Switzerland
Fundación Pública Andaluza Progreso y Salud
Karolinska Institutet; Eli Lilly and Company; Medical University of Vienna; Sanofi and other collaborators

Completed

Molecular Reclassification to Find Clinically Useful Biomarkers for Systemic Autoimmune Diseases: Case-control (PRECISESADST)

Healthy Subjects

France, Austria, Germany, Portugal, Hungary, Belgium, Italy, Spain, Switzerland
Merck KGaA, Darmstadt, Germany

Completed

A Study of Efalizumab in Participants With Moderate to Severe Chronic Psoriasis Who Have Failed, Have a Contraindication to, or Are Intolerant of Other Systemic Therapies

Psoriasis

United Kingdom
Duke University

Terminated

Pharmacokinetics of Systemic Anti-Cancer Therapies in the Cerebrospinal Fluid (CSF) of Patients With Advanced Cancer

Advanced Cancer | Brain Metastasis | Metastatic Cancer Patients on an Anti-cancer Therapy

United States
Institute of Cancer Research, United Kingdom

Terminated

Evolution of Resistance to Systemic Therapies in Patients With Breast Cancer (EVOLUTION)

Metastatic Breast Cancer

United Kingdom
Chinese PLA General Hospital
Xijing Hospital; Shandong Provincial Hospital; Shandong University of Traditional...

Unknown

Low-frequency Rotating Magnetic System Combined With Systemic Anti-tumor Therapy for Advanced Lung Cancer

Lung Neoplasms

China
Centro Nacional de Investigaciones Oncologicas...
Apices Soluciones S.L.; Hospital Universitario de Fuenlabrada; Grupo Hospital...

Completed

Study of Individualized Therapies Selection for Patients With Metastatic Colorectal Carcinoma According to the Therapeutic

Metastatic Disease | Adenocarcinoma of Rectum | Adenocarcinoma of Colon

Spain
Fundación Pública Andaluza Progreso y Salud

Completed

Study of the Impact of the Minimum Inhibitory Concentration and Susceptible Cut-off Points (CLSI, EUCAST, and Pharmacokinetics/Pharmacodynamics)in Prognosis of Bacteremia by Enterobacteriaceae (BACTERIEMIA)

Bacteremia by Enterobacteriaceae

Spain
Fundación Pública Andaluza Progreso y Salud

Terminated

Efficacy of a Short-term Sequential Therapy in Non-complicated Catheter Related Bacteremia by Methicillin- Susceptible S.Aureus.

Staphylococcus

Spain
Fundación Pública Andaluza Progreso y Salud
Ministry of Health, Spain

Terminated

Comparison of the Efficacy of Two Rituximab Treatment Regimens in Patients With Lupus Nephropathy (RITULUP)

Lupus Nephritis

Spain
Fundación Pública Andaluza Progreso y Salud

Completed

Staphylococcus Aureus Bacteremia: Impact of an Intervention Program in Improving the Clinical Management and Review of the Clinical and Molecular Epidemiology

Staphylococcus Aureus Bacteremia

Spain
Astellas Pharma Inc

Completed

Study of Micafungin in Patients With Invasive Candidiasis or Candidemia

Candidemia | Candidiasis

Belgium, France, Germany, Spain, United States, India, Canada, Brazil, Switzerland, Austria, Croatia, Netherlands, Poland, Czech Republic, United Kingdom
Merck KGaA, Darmstadt, Germany

Terminated

ChangE From Any Systemic psoriasiS therapY to Raptiva (EASY)

Chronic Plaque Psoriasis

Canada
Ministry of Health, Bhutan
Menzies School of Health Research; Asia Pacific Malaria Elimination Network

Unknown

Parasitic Clearance and Recurrence Rates Among Patients With Vivax Malaria (BCAPES)

Parasitemia

Bhutan
Rady Children's Hospital, San Diego
University of California, San Diego

Unknown

Systemic Therapies for Pediatric Atopic Dermatitis

Dermatitis, Atopic

United States
Asan Medical Center

Unknown

Early Continuous Renal Replacement Therapies (CRRT) in Patients With Severe Sepsis or Septic Shock With Acute Kidney Injury

Septic Shock | Acute Kidney Injury | Severe Sepsis

Korea, Republic of
Charite University, Berlin, Germany

Completed

Sildenafil for Treatment of Digital Ulcers in Patients With Systemic Sclerosis (Sildenafil)

Active Digital Ulcers

Germany
National Institute of Allergy and Infectious Diseases...

Completed

An Open Label Pilot Study Examining the Use of Rituximab in Patients With Wegener's Granulomatosis Who Have Experienced Disease Relapse on Standard Therapies

Wegener's Granulomatosis

United States
Peking Union Medical College Hospital
Central South University; Zhejiang University; Beijing Children's Hospital; Shenzhen... and other collaborators

Recruiting

Observational Study of Pediatric Rheumatic and Immunologic Diseases in China: The CAPRID Registry

Autoimmune Diseases | Autoinflammatory Diseases

China
PersonGen BioTherapeutics (Suzhou) Co., Ltd.

Not yet recruiting

Preliminary Clinical Study of UTAA09 Injection in the Treatment of Relapsed/Refractory Autoimmune Diseases

Rheumatoid Arthritis | Systemic Lupus Erythematosus | Systemic Sclerosis | Immune Thrombocytopenia | Sjogren's Syndrome | Idiopathic Inflammatory Myopathies | Primary Biliary Cholangitis
IRCCS San Raffaele

Recruiting

INfectious DIsease REgistry BIObank (INDI-REBIO)

Central Nervous System Infections | Infective Endocarditis | Vertebral Osteomyelitis | Bone and Joint Infections | Bloodstream Infections | Endovascular Infections | CIED-related Infections

Italy
Liangjing Lu
Shanghai Ming Ju Biotechnology Co., Ltd.

Not yet recruiting

Relmacabtagene Autoleucel for the Treatment of Systemic Sclerosis

Systemic Sclerosis

China
Indonesia University

Not yet recruiting

Comparison Between Split Septum and Mechanical Valve Needleless Connector in Preterm Babies

Sepsis, Neonatal
Central Hospital, Nancy, France

Not yet recruiting

Evaluation of Patients With Systemic Sclerosis Without Specific or Associated Autoantibodies (SCLERONAB)

Systemic Sclerosis

France
IRCCS Ospedale San Raffaele

Not yet recruiting

Validation of Human Drugs Target of Repurposed Drugs and Novel Therapies

Rare Diseases | Corneal Neovascularization | Limbal Stem Cell Deficiency | Aniridia | Neurotrophic Keratopathy | Ocular Cicatricial Pemphigoid | Ocular Graft-versus-host Disease | EEC Syndrome
GlaxoSmithKline

Not yet recruiting

A Study to Investigate the Safety and Pharmacological Effect of a Single Intravenous Infusion of Belantamab in Male and Female Participants Aged 18 to 75 With Moderate to Severe Systemic Lupus Erythematosus

Systemic Lupus Erythematosus

United States
GlaxoSmithKline

Not yet recruiting

A Study Describing the Efficacy and Safety of Belimumab Administered in Adult Participants With Early Systemic Lupus Erythematosus (SLE) (BE-EARLY)

Systemic Lupus Erythematosus
Novartis Pharmaceuticals

Not yet recruiting

Home Reported Outcomes in PNH

Paroxysmal Nocturnal Hemoglobinuria
Novartis Pharmaceuticals

Not yet recruiting

Pharmacokinetics Study of Ianalumab in Chinese Participants With Autoimmune Diseases

Systemic Lupus Erythematosus | Sjogren Disease
Centre for Human Drug Research, Netherlands

Recruiting

Deep Phenotyping of Cutaneous Lupus Erythematosus

Cutaneous Lupus Erythematosus

Netherlands

Search clinical trials for: systemic therapies

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