Search clinical trials for: thorough qt study

Total 118558 results

Cortexyme Inc.

Completed

GAIN Trial: Phase 2/3 Study of COR388 in Subjects With Alzheimer's Disease

Alzheimer Disease

United States, Spain, Poland, United Kingdom, France, Netherlands
BioLineRx, Ltd.
Celerion

Completed

Study to Investigate the Effect of BL-8040 (Motixafortide) on the QTc Interval in Healthy Subjects

Healthy Subjects

United States
Eli Lilly and Company
Loxo Oncology, Inc.

Completed

A Study of Effect of Selpercatinib (LY3527723) on Corrected QT (QTc) Interval in Healthy Participants

Healthy

United States
Takeda

Withdrawn

A Study of Soticlestat in Healthy Adults To Evaluate the Effect on QTc Interval

Healthy Volunteers
Taisho Pharmaceutical Co., Ltd.

Completed

A QT/QTc Evaluation Study of TS-142 in Healthy Adult Subjects

Healthy Subjects

Japan
Astex Pharmaceuticals, Inc.

Completed

Thorough QT Assessment of Cedazuridine in Healthy Subjects

Healthy Volunteers

Netherlands
QT Ultrasound LLC

Active, not recruiting

Clinical PRoduct DevelOpment StudyinG the QT Ultrasound® BReast ScannEr With Volunteer SubjectS (PROGRESS)

Volunteer Subjects

United States
Connect Biopharma Australia Pty Ltd

Completed

A Study to Investigate the Effects of CBP-307 on the Heart Rate-corrected QT Interval (QTc) in Healthy Subjects

Autoimmune Diseases

Australia, United States
Daiichi Sankyo Co., Ltd.
AstraZeneca

Completed

Phase 1 Study to Evaluate the Effect of DS-8201a on the QT/QTc Interval and Pharmacokinetics in HER2-Expressing Breast Cancer

Malignant Neoplasm of Breast

Japan
University of Rochester
Gilead Sciences

Completed

Long-term Efficacy Study of Sodium Channel Blocker in LQT3 Patients

Long QT Syndrome

United States
AMAG Pharmaceuticals, Inc.

Completed

A Study of the Electrocardiogram Effects and Pharmacokinetics of Ferumoxytol in Healthy Men and Women

Anemia

United States
Concert Pharmaceuticals

Completed

A Randomized Study to Evaluate the Effects of CTP-543 on the QT/QTc Intervals in Health Volunteers

Healthy Volunteers

United States
Alexion Pharmaceuticals
Celerion

Completed

A Study of the Cardiac Effects of ALXN2050 in Healthy Adults

Healthy

United States
Corcept Therapeutics

Completed

T/QT Study to Investigate the Effect of Relacorilant on Cardiac Repolarization in Healthy Volunteers

Healthy

United States
Alexion Pharmaceuticals
Achillion, a wholly owned subsidiary of Alexion

Completed

A Study of the Cardiac Effects of Danicopan in Healthy Adults

Healthy

United States
BioMarin Pharmaceutical

Completed

A Phase 1 Study to Evaluate Effects of Sapropterin Dihydrochloride on QTc Intervals in Healthy Adult Subjects

Phenylketonuria

United States
University Hospital, Bordeaux

Completed

Study of Arrhythmia and ECG Abnormalities in Patients With COVID-19 (RYTHMO-COV)

Arrhythmia | SARS-CoV-2 Infection

France
Shire

Completed

Guanfacine Immediate-release Electrocardiogram Results (QTc) Study

Healthy Volunteers

United States
Acerta Pharma BV

Completed

A Study to Evaluate the Effect of ACP-196 on the Heart Rate-corrected QT Interval in Healthy Adult Participants

Healthy Volunteers

United States
XenoPort, Inc.

Completed

A Study to Evaluate the Effect of Gabapentin on Cardiac Repolarization in Healthy Volunteers

Restless Legs Syndrome

United States
QT Ultrasound LLC

Completed

Case Collection Study to Determine the Accuracy, Call Back and Cancer Detection Rates of QT Ultrasound in Breast Imaging (ACCRUE)

Breast

United States
QT Ultrasound LLC

Completed

Case Collection Study in the Evaluation of Doubling Time Rates in Non-Suspicious Breast Masses Using QT Ultrasound Technology (EVALUATE)

Breast Fibroadenoma

United States
Nantes University Hospital

Completed

CIQTP Prolongation : Role and Mechanism in Sudden Cardiac Death (IQARE-SCD)

Sudden Cardiac Death

France
Cancer Institute and Hospital, Chinese Academy...
QTC care

Suspended

A Real-world Clinical Study of Kapok Initiative

Quality of Life

China
University of Pisa

Unknown

SGLT-2 and DPP-4 Inhibition, Subclinical Inflammation of the Genito-urinary Tract and Risk of Infections. (UTI-flog)

Type 2 Diabetes | Urinary Tract Infections

Italy
Gilead Sciences

Completed

Study to Evaluate the Effect of Eleclazine on QT, Safety, and Tolerability in Participants With Long QT2 Syndrome

LQT2 Syndrome

United States
Pfizer

Withdrawn

A Study To Evaluate The Safety And Efficacy Of PF-06826647 In Participants With Moderate To Severe Ulcerative Colitis

Ulcerative Colitis

United States
Teva Pharmaceuticals USA

Withdrawn

An Open-Label, Single-Center Study to Evaluate the Exposure-Response Relationship Between the Plasma Drug Concentrations and the Change From Baseline in QTc at Steady State Following Once-daily Administration of CASSIPA® in Opioid Dependent Subjects.

Evaluation of QTc Interval
Kyowa Kirin Co., Ltd.

Completed

A Through QT/QTc Study of KW-6356

Parkinson's Disease

Japan
Knight Therapeutics (USA) Inc

Completed

Dedicated QT Study in Bolivian Patients Taking Impavido® (Miltefosine) for Mucocutaneous Leishmaniasis

Mucocutaneous Leishmaniasis

Bolivia
Rabin Medical Center

Unknown

Voriconazole-Induced QT Interval Prolongation: A Prospective Study

Voriconazole Induced QT Interval Prolongation

Israel
Hoffmann-La Roche

Completed

Study to Investigate the Effect of Balovaptan on the QTC Interval in Healthy Subjects

Healthy Volunteers

United States
GlycoMimetics Incorporated

Completed

A Study to Evaluate the Effect of IV Doses of GMI-1070 on Qtc Intervals in Healthy African-American Adult Subjects

Healthy

United States
Zydus Therapeutics Inc.

Completed

A Study to Evaluate the Effect of Saroglitazar Magnesium on the QTc Interval in Healthy Volunteers

Healthy

India
Bayer
Merck Sharp & Dohme LLC

Completed

Study to Evaluate the QT / QTc Interval Prolongation Potential of Vericiguat

Coronary Artery Disease

Germany, Moldova, Republic of, Netherlands
Institute of Hematology & Blood Diseases Hospital

Unknown

A Study of BCMA-directed CAR-T Cells Treatment in Subjects With r/r Multiple Myeloma

Multiple Myeloma

China
Institute of Hematology & Blood Diseases Hospital
Shanghai Cell Therapy Engineering Technology Research Center Group Co., Ltd.

Unknown

Exploratory Study of CD19-targeted Chimeric Antigen Receptor T Cells(BZ019) for Relapsed and Refractory B-cell Lymphoma

Diffuse Large B Cell Lymphoma | High-grade B-cell Lymphoma | Primary Mediastinal Large B Cell Lymphoma | Transformed Lymphoma

China
Spero Therapeutics
Celerion

Completed

A Single-Dose, Randomized, Placebo- and Active-Control, Four-Way, Cross-Over Study for the Evaluation of the Effect of Tebipenem Pivoxil Hydrobromide (TBPM-PI-HBr) on the QT/QTc Intervals in Adult Healthy Subjects

TQT Study

United States
Cara Therapeutics, Inc.

Completed

Study to Investigate the Effects of Single Intravenous Doses of Difelikefalin (CR845) on the QTc Interval in Healthy Subjects

Healthy

United States
AstraZeneca
Parexel

Completed

A Study to Investigate the Effect of Single Dose of AZD6094 (600 mg) on Cardiac Repolarization in Healthy Volunteers

Solid Tumors

United States
Food and Drug Administration (FDA)
Spaulding Clinical Research LLC

Completed

CiPA Phase 1 ECG Biomarker Validation Study

Pharmacokinetics | Pharmacodynamics | Drug-induced QT Prolongation

United States
Celgene

Completed

A Phase 1 QT Study in Healthy Male Subjects (QT/QTc)

Clinical Pharmacology, Healthy Volunteer Study

United States
NorthSea Therapeutics B.V.

Completed

A Study to Evaluate the Effects of NST-4016 on QT/Corrected QT (QTc) Interval

Dyslipidemias

United Kingdom
Celgene

Completed

A Phase I Study to Assess the Safety, Pharmacokinetics, and Potential Effects of Amrubicin on the QT/QTc Interval in Cancer Patients With Advanced Solid Tumors.

Advanced Solid Tumors

United States
Pfizer

Completed

A Study To Determine The Effect Of Single-dose PF-04965842 On QTc Interval In Healthy Volunteers Compared With Placebo and Moxifloxacin

Healthy Volunteers

Belgium
Pfizer

Completed

A Phase 1 Study To Evaluate The Effect Of Glasdegib On The Cardiac Repolarization In Healthy Subjects (B1371023)

Healthy Volunteers

Belgium
Entasis Therapeutics

Completed

Study Evaluating the Effect of ETX2514 on Cardiac Repolarization in Healthy Male or Female Volunteers

Acinetobacter Baumannii-calcoaceticus Complex Infections

United States
Mitsubishi Tanabe Pharma Corporation

Completed

A Study to Evaluate the Effect of MCI-186 at Therapeutic and Supra-Therapeutic Doses on the QT Interval(QT)/Corrected QT Interval(QTc) Interval in Healthy Subjects

Healthy Adult Subjects

Japan
Novartis Pharmaceuticals

Completed

Open-label, Multi-center Protocol to Provide QTI571 to PAH Patients Who Participated in the Extension Study (A2301E1) in Japan

Severe Pulmonary Arterial Hypertension

Japan
Merck Sharp & Dohme LLC

Completed

A Study to Evaluate the Effect of MK-8669 (Ridaforolimus) on QTc Interval in Participants With Advanced Cancer (MK-8669-037)

Metastatic or Locally Advanced Cancer

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