Search clinical trials for: toxicity adjusted dose

Total 22622 results

Baylor College of Medicine
National Cancer Institute (NCI)

Completed

Dose Adjusted EPOCH-R, to Treat Mature B Cell Malignancies (DA-EPOCH-R)

Diffuse Large B Cell Lymphoma | Post Transplant Lymphoproliferative Disorder | Primary Mediastinal (Thymic) Large B-cell Lymphoma

United States
National Cancer Institute (NCI)

Completed

Phase II Study of Dose-Adjusted EPOCH-Rituximab in Adults With Untreated Burkitt Lymphoma and c-MYC+ Diffuse Large B-Cell Lymphoma

Burkitt Lymphoma | Plasmablastic Lymphoma | Diffuse Large B-cell Lymphoma, c-MYC Positive

United States
National Cancer Institute, Naples

Active, not recruiting

STAD-1 Small Cell Lung Cancer Toxicity Adjusted Dosing Study (STAD-1)

Small Cell Lung Cancer

Italy
Institut Cancerologie de l'Ouest

Completed

Efficacy and Tolerance Evaluation in FOLFIRINOX Dose Adjusted in Elderly Patients With a Metastatic Pancreatic Cancer (PAMELA70)

Toxicity | Pancreatic Metastatic Cancer

France
National Cancer Institute (NCI)

Completed

Phase 1 Trial of Siplizumab and Dose-Adjusted EPOCH-Rituximab in T- and NK-Cell Lymphomas

Subcutaneous Panniculitis-Like T-Cell Lymphoma | T-Cell Peripheral Lymphoma | Gamma Delta Hepatosplenic T-Cell Lymphoma | NK T-Cell Lymphoma

United States
Hospital Universitario Principe de Asturias

Unknown

DA-EDOCH14-R in Poor-prognosis Diffuse Large B-cell Lymphoma

Diffuse Large B-Cell Lymphoma (DLBCL)

Spain
Fondazione Policlinico Universitario Agostino Gemelli...

Not yet recruiting

Evaluation of Ultraaccelerated High Dose Rate Intrauterine Interventional Radiotherapy (EROS3)

Locally Advanced Cervical Carcinoma
Beijing Hospital of Traditional Chinese Medicine

Not yet recruiting

A Multicentre Randomized Controlled Clinical Study on the Chitosan Nanocrystalline Qinteng Huoxue Runji Ointment Therapy for Psoriasis With Blood Stasis Syndrome.

Plaque Psoriasis
Institute of Hematology & Blood Diseases Hospital...

Not yet recruiting

Efficacy and Safety of Low-dose Chemotherapy Plus Immuno-targeted Drugs in Newly Diagnosed Elderly/Unfit Ph- B-ALL

Precursor Cell Lymphoblastic Leukemia-Lymphoma
Valenta Pharm JSC

Recruiting

Pharmacokinetics and Bioequivalence of Doxylamine+Pyridoxine and Diclectin

Nausea

Russian Federation
Omar Mahmoud

Not yet recruiting

Dose Adjusted Chemoradiotherapy in HPV-Associated Oropharynx Cancer of the Elderly ((DACHOC-E))

Frailty | Oropharynx Cancer
National Institute of Diabetes and Digestive and...

Not yet recruiting

Variability In Mixed Meal Tests: Fixed Versus Adjusted to Energy Needs Caloric Dose

Obesity | Healthy Volunteer

United States
University of Oklahoma

Not yet recruiting

Relugolix + Enzalutamide Study in High-Risk Prostate Cancer

Androgen Deprivation Therapy | Locally Advanced Prostate Cancer

United States
Sohag University

Not yet recruiting

Evaluation of High Dose Methotrexate Toxicity

Methotrexate Toxicity
Rajiv Gandhi Cancer Institute & Research Center...
Varian, a Siemens Healthineers Company

Recruiting

Dose Escalation Using Hypoxia-adjusted Radiotherapy (DE-HyART)

Head and Neck Squamous Cell Carcinoma

India
CHU de Quebec-Universite Laval

Recruiting

A Trial Evaluating Toxicity of SBRT and LDRB in Localized Prostate Cancer.

Prostate Cancer

Canada
Sichuan Enray Pharmaceutical Sciences Company

Recruiting

Carbon Nanoparticle-Loaded Iron [CNSI-Fe(II)] in the Treatment of Advanced Solid Tumor (CNSI-Fe(II))

Cervical Cancer | Breast Cancer | Colorectal Cancer | Ovarian Cancer | Lung Cancer | Advanced Solid Tumor | Pancreas Cancer | Thyroid Cancer | Vulva Cancer

China
Region Örebro County
Helsinki University Central Hospital; Hospital Clinic of Barcelona; University... and other collaborators

Recruiting

Implementing Geriatric Assessment for Dose Optimization of Cyclin-dependent Kinase (CDK) 4/6-inhibitors in Older Breast Cancer Patients (IMPORTANT)

Quality of Life | Advanced Breast Cancer | Metastatic Breast Cancer | Toxicity | Older Patients

Sweden, Finland, Greece, Italy, Norway, Spain
Hospital Juarez de Mexico

Recruiting

Vitamin C and Zinc in Patients With Enterocutaneous Fistulas. (VITAC)

Enterocutaneous Fistulas

Mexico
Yale University
Kyowa Kirin, Inc.

Not yet recruiting

Study of Mogamulizumab With DA-EPOCH in Patients With Aggressive T Cell Lymphoma

T Cell Lymphoma

United States
Novartis Pharmaceuticals

Recruiting

A Phase I/II, Open-label, Multi-center Study of [225Ac]Ac-PSMA-R2 in Men With PSMA-positive Prostate Cancer With or Without Prior 177Lu-PSMA Radioligand Therapy.

Metastatic Castration-resistant Prostate Cancer (mCRPC)

France
Cari Health Inc.
Samplimy Medical AB

Recruiting

Assessment of Methadone Dose Taken Using Electrochemistry

Pain, Chronic | Metabolism Medication Toxicity | Methadone Toxicity | Methadone Overdose | Drug Metabolism, Poor, CYP2D6-Related

United States
Centre Francois Baclesse

Recruiting

Phase II Study of Intensity Modulated Radiotherapy in Dose Painting for Sinus Carcinomas After Endoscopic Surgery (SinocaRT)

Tumor, Solid

France
University of Cincinnati

Recruiting

REDEL Trial: Reduced Elective Nodal Dose for Anal Cancer Toxicity Mitigation (REDEL)

Anal Cancer

United States
Protherics Medicines Development Limited
Resonance Health

Recruiting

Retrospective Registry Study of Patients With Cancer Treated With High-dose Methotrexate

Acute Kidney Injury | Drug Toxicity

Spain, France, Italy
Seoul St. Mary's Hospital
GE Healthcare

Not yet recruiting

Low-dose Contrast Media for Low-kVp Abdomen CT

Appendicitis Acute
Moi University
Amsterdam UMC, location VUmc; Princess Maxima Center for Pediatric Oncology

Recruiting

CHildren Treated With Vincristine: A Trial Regarding Pharmacokinetics, DNA And Toxicity of Targeted Therapy In Pediatric Oncology Patients. (CHAPATI)

Pediatric Cancer

Kenya
Ottawa Hospital Research Institute

Recruiting

Evaluating an Endocrine Therapy Dose-frequency Escalation Strategy and Its Effects on Tolerability and Compliance (REaCT-TEMPO)

Breast Cancer

Canada
University Hospital, Geneva

Recruiting

Bleeding of Unknown Cause: a Swiss Case-control Study (SWISS-BUC)

Bleeding Disorder

Switzerland
Instituto Brasileiro de Controle do Cancer

Recruiting

Efficacy and Safety of Ultra_HYPofractionated RadiotHerapy in Women With BrEast CaNcer Receiving Regional Nodal Radiation vs Nodal Moderate Hypofractionated Radiotherapy (HYPHEN)

Malignant Breast Neoplasm

Brazil
Brigham and Women's Hospital

Recruiting

First in Human Phase 1 Ascending Dose Study of PanChol in Healthy Volunteers

Cholera | Cholera Vaccine Toxicity

United States
SRI International

Recruiting

Study of Single Oral Doses of HOPO 14-1 Evaluating Safety, Tolerability, Pharmacokinetics

Toxicity;Chemical

United States
Indiana University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

STTEPP: Safety, Tolerability and Dose Limiting Toxicity of Lacosamide in Patients With Painful Chronic Pancreatitis (STTEPP)

Chronic Pain | Opioid-Related Disorders | Opioid Use Disorder | Opioid Dependence | Chronic Pancreatitis | Hyperalgesia | Chronic Pain Syndrome | ERCP | Pancreatic Surgery | Chronic Abdominal Pain

United States
University of Rochester
Medical College of Wisconsin

Recruiting

A Study to Determine the Preferred Dose of the Drug, Lisinopril, for Preventing Urinary Toxicity Following Radiotherapy for Prostate Cancer

Prostate Cancer | Radiation Toxicity | Urinary Complication

United States
University Medical Center Groningen
Radboud University Medical Center; Maastricht University Medical Center; Erasmus... and other collaborators

Recruiting

Comparison of Standard Dose Alectinib to Alectinib in Adjusted Dose Based on Alectinib Bloodlevels (ADAPT ALEC)

Carcinoma, Non-Small-Cell Lung | Lung Cancer | Drug Monitoring | Anaplastic Lymphoma Kinase Gene Mutation | Anaplastic Lymphoma Kinase Gene Translocation

Netherlands, France
National Cancer Institute (NCI)

Recruiting

Pomalidomide and Dose-Adjusted EPOCH +/- Rituximab for HIV-Associated Lymphomas

Burkitt Lymphoma | Plasmablastic Lymphoma | Non-Hodgkin Lymphoma | Diffuse Large Cell Lymphoma | B-Cell Neoplasm

United States
Amsterdam UMC, location VUmc
Dutch Cancer Society

Recruiting

Single-dose Preoperative Partial Breast Irradiation in Low-risk Breast Cancer Patients (ABLATIVE-2)

Breast Cancer

Netherlands
Central Hospital, Nancy, France
PAPE Elise

Not yet recruiting

Peritoneal Diffusion and Efficacy of Antibiotic Therapy in Pediatric Peritonitis (DIFFUPERPED)

Appendicitis | Peritonitis | Children, Only | Antibiotic Toxicity
Medical College of Wisconsin

Recruiting

High Dose Re-Irradiation Utilizing Advanced Deformable Image Registration (DIR) and Individualized Organ At Risk (OAR) Dose Calculations With Organ Specific Toxicity Analysis (REDIRICT)

Solid Tumor

United States
Anhui Provincial Hospital

Recruiting

Hypofraction Radiotherapy for Locally Advanced Non-small Cell Lung Cancer

Non-small Cell Lung Cancer | Toxicity Due to Radiotherapy

China
University Hospital, Caen

Not yet recruiting

Height Adjusted Versus Standardized Dose of Bupivacaine for Spinal Anesthesia (RAMCES)

Cesarean Section Complications | Regional Anesthesia Morbidity | Local Anesthetic Complication
Hospital General de Mexico

Recruiting

Efficacy of the Use of Bortezomib for the Treatment of Relapsed Leukemia or Positive MRD

Acute Lymphoblastic Leukemia, in Relapse | Chemotherapeutic Toxicity | Minimal Residual Disease

Mexico
Sheba Medical Center
Rambam Health Care Campus; AstraZeneca; Tel-Aviv Sourasky Medical Center

Recruiting

Concomitant Radiotherapy, Tremelimumab & Durvalumab for Advanced NSCLC Patients Progressing on First-line Immunotherapy (CORAL-Lung)

Metastatic or Locally Advanced NSCLC

Israel
National Cheng-Kung University Hospital
China Medical University Hospital; Taipei Veterans General Hospital, Taiwan; Kaohsiung... and other collaborators

Recruiting

Perioperative Leucovorin, Oxaliplatin, Docetaxel and S-1 (LOTS) For Locally Advanced Gastric or Gastroesophageal Junction Cancer (LOTS)

Gastric Cancer | Gastric Adenocarcinoma | Toxicity Due to Chemotherapy | Effects of Chemotherapy

Taiwan
Vejle Hospital

Recruiting

Shared Decision Making on Radiation Dose for Lung Malignancies

Lung Cancer, Non-small Cell | Lung Metastases | Radiation Toxicity | Stereotactic Body Radiation Therapy | Decision Making, Shared

Denmark
Tu Dan
Incyte Corporation

Recruiting

Ruxolitinib for Cancer Cachexia

Cachexia | Stage IV Non-small Cell Lung Cancer

United States
Advenchen Laboratories Nanjing Ltd.

Recruiting

A Phase I Study of AL8326 in Advanced Solid Tumor

Advanced Solid Tumors

China
Hospices Civils de Lyon

Recruiting

NIRAPK : Study of the Relationship(s) Between Clinical, Biological and Pharmacokinetic Metrics and Toxicities When Niraparib is Used as Maintenance Treatment for Ovarian Cancer Patients. (NIRAPK)

Adult Patients With Platinum-sensitive, Relapsed, High Grade Serous Epithelial Ovarian Cancer

France
Radboud University Medical Center
UMC Utrecht; Catharina Ziekenhuis Eindhoven; Amsterdam UMC, location VUmc; Academisch... and other collaborators

Recruiting

Aerobic Fitness or Muscle Mass Training to Improve Colorectal Cancer Outcome (AMICO)

Colorectal Cancer | Chemotherapeutic Toxicity | Lifestyle | Survivorship

Netherlands
Kiyuk Chang, MD,PhD

Recruiting

Low Dose Rosuvastatin Plus Ezetimibe Versus High-dose Rosuvastatin in AMI (ROSUZET-AMI)

Myocardial Infarction | Statin Adverse Reaction | HMG-CoA Reductase Inhibitor Toxicity

Korea, Republic of

Search clinical trials for: toxicity adjusted dose

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