Search clinical trials for: varying degrees of exertion

Total 431171 results

The Cleveland Clinic

Completed

Accuracy of Commercially Available Heart Rate Monitors (HRM)

Healthy
The Cleveland Clinic

Completed

Accuracy of Commercially Available Heart Rate Monitors II

Healthy
BioVersys AG
CRU Hungary Kft

Recruiting

A Study to Assess the Phamacokinetics of BV100 in Participants With Varying Degrees of Hepatic Impairment

Healthy Participants

Hungary
PharmaMar

Recruiting

Clinical Pharmacokinetic Study of Lurbinectedin in Patients With Advanced Solid Tumors and Varying Degrees of Hepatic Impairment

Hepatic Impairment | Advanced Solid Tumor

Spain
Pfizer

Completed

STUDY OF PF-06882961 IN PARTICIPANTS WITH TYPE 2 DIABETES MELLITUS WITH VARYING DEGREES OF RENAL IMPAIRMENT AND PARTICIPANTS WITHOUT RENAL IMPAIRMENT

Healthy | Diabetes Mellitus, Type 2 | Renal Impairment

United States
Pfizer

Completed

STUDY OF PF-06882961 IN PARTICIPANTS WITH AND WITHOUT VARYING DEGREES OF HEPATIC IMPAIREMENT

Healthy Volunteers | Hepatic Impairment

United States
Ensoma

Completed

Study Assessing PK and Safety of MGTA-145 in Subjects With Normal Estimated GFR and Varying Degrees of Renal Impairment

Healthy | Renal Insufficiency

United States
Venatorx Pharmaceuticals, Inc.
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Ceftibuten/VNRX-7145 in Participants With Varying Degrees of Renal Function

Pharmacokinetics

United States
Madrigal Pharmaceuticals, Inc.

Completed

Phase 1 Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Multiple Oral Doses of MGL-3196 in Subjects With Varying Degrees of Hepatic Impairment and Healthy Matched Control Subjects

Hepatic Impairment | NASH - Nonalcoholic Steatohepatitis | Cirrhosis, Liver

United States
AstraZeneca

Completed

Study to Evaluate the Pharmacokinetics of CIN-107 in Subjects With Varying Degrees of Renal Function

Hypertension

United States
VA Office of Research and Development
University of Washington

Active, not recruiting

Orthotic Dose Response Study (ODRS)

Ankle Osteoarthritis | Flat Foot or Pes Planus

United States
Taiho Oncology, Inc.

Completed

Evaluating Patients With Varying Degrees of Renal Function

Renal Impairment

United States
Kadmon, a Sanofi Company

Completed

KD025 Hepatic Impairment Study With Normal Hepatic Function and Subjects With Varying Degrees of Hepatic Impairment

Hepatic Impairment

United States
Galectin Therapeutics Inc.

Completed

A Single-dose, Open-label, Pharmacokinetic Study of Belapectin (GR-MD-02) in Subjects With Normal Hepatic Function and Subjects With Varying Degrees of Hepatic Impairment

Hepatic Impairment

United States
Janssen Research & Development, LLC

Completed

A Study to Evaluate JNJ-64565111 Pharmacokinetics and Safety in Adult Participants With Varying Degrees of Renal Function

Kidney Failure, Chronic

United States
Bristol-Myers Squibb

Completed

A Single-dose Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of BMS-986263 in Participants With Varying Degrees of Liver Impairment

Hepatic Impairment

United States
Rhythm Pharmaceuticals, Inc.

Completed

A Phase 1 Study to Evaluate the Pharmacokinetics of Setmelanotide in Subjects With Varying Degrees of Renal Impairment

Renal Insufficiency

United States
Novartis Pharmaceuticals

Completed

PK and Safety of Midostaurin in Subjects With Impaired Hepatic Function and Subjects With Normal Hepatic Function

Hepatic Impairment

Germany, Belgium, Lithuania, United States, Bulgaria, Romania
GlaxoSmithKline
Biomedical Advanced Research and Development Authority

Completed

Pharmacokinetics (PK) Study of Gepotidacin (GSK2140944) in Adult Subjects With Varying Degrees of Hepatic Impairment and in Matched Control Subjects With Normal Hepatic Function

Infections, Bacterial

United States
Novartis Pharmaceuticals

Completed

A Phase l Study to Evaluate the Pharmacokinetics and Safety Pasireotide in Subjects With Varying Degrees of Renal Impairment Compared to Healthy Volunteers

Renal Impairment

Germany, South Africa
Novartis Pharmaceuticals

Completed

Pharmacokinetics and Safety of Single Subcutaneous Pasireotide (SOM230) in Subjects With Varying Degrees of Hepatic Function

Alcoholism | Hepatic Cirrhosis

Germany, Belgium, United States, South Africa
Novartis Pharmaceuticals

Completed

A Study of Patupilone in Patients With Advanced Solid Tumors and Varying Degrees of Hepatic Function

Advanced Malignancies | Tumors

United States
Zealand Pharma

Completed

Pharmacokinetic Profile of Glepaglutide After a Single Injection in Subjects With Varying Degrees of Renal Function

Renal Impairment

Hungary, Poland
GlaxoSmithKline

Completed

Pharmacokinetic Study of Gepotidacin in Subjects With Varying Degrees of Renal Impairment and in Subjects With Normal Renal Function

Infections, Bacterial

United States
National Cancer Institute (NCI)

Completed

Pazopanib to Treat Adults With Advanced Cancers and Varying Degrees of Liver Function

Neoplasms | Lymphoma

United States
Pfizer

Completed

Study of PF-05221304 in Subjects With Varying Degrees of Hepatic Impairment

Hepatic Impairment

United States, Belgium, Czechia, Slovakia
National Cancer Institute (NCI)

Completed

Belinostat for Solid Tumors and Lymphomas in Patients With Varying Degrees of Hepatic Dysfunction

Neoplasms | Lymphomas

United States
Eli Lilly and Company

Completed

A Study of Abemaciclib in Participants With Varying Degrees of Liver Impairment

Hepatic Insufficiency

United States
Lexicon Pharmaceuticals

Completed

Study to Evaluate Sotagliflozin in Subjects With Varying Degrees of Renal Function

Healthy | Renal Impairment

United States
Cubist Pharmaceuticals LLC

Completed

Study of Pharmacokinetics of a Single IV Dose of CB-238,618 in Subjects With Varying Degrees of Renal Impairment Compared to Healthy Subjects (MK-6183-001)

Renal Impairment | Healthy Volunteers
Venatorx Pharmaceuticals, Inc.
National Institutes of Health (NIH)

Completed

VNRX-5133 With VNRX-5022 in Subjects With Varying Degrees of Renal Impairment

Pharmacokinetics

United States
Millennium Pharmaceuticals, Inc.

Completed

Pharmacokinetics of Alisertib in Adults With Advanced Solid Tumors or Relapsed/Refractory Lymphoma With Varying Degrees of Hepatic Function

Advanced Solid Tumors | Relapsed/Refractory Lymphoma

United States
Rempex Pharmaceuticals (a wholly owned subsidiary...

Completed

The Safety and Pharmacokinetics of Carbavance™ (RPX2014/RPX7009) in Subjects With Renal Insufficiency

Subjects With Varying Degrees of Renal Insufficiency and | Subjects With Normal Renal Function

United States
Amgen

Completed

Study of the Safety and Pharmacokinetics of Carfilzomib in Patients With Relapsed and Refractory Multiple Myeloma and Varying Degrees of Renal Function

Renal Insufficiency | Multiple Myeloma

United States
Hoffmann-La Roche

Completed

A Study of RO4998452 in Type 2 Diabetes Patients With Varying Degrees of Renal Impairment

Diabetes Mellitus Type 2

United States, Russian Federation
Genentech, Inc.

Completed

A Study of Vismodegib in Patients With Advanced Solid Malignancies Including Hepatocellular Carcinoma With Varying Degrees of Renal or Hepatic Function

Cancer

United States
Pfizer

Completed

A Study To Investigate The Pharmacokinetics, Safety And Tolerability Of An Intravenous And Oral Form Of A Compound In Subjects With Varying Degrees Of Renal Impairment And Normal Renal Function

Pneumonia

Belgium, United States
Cubist Pharmaceuticals LLC
Syneos Health

Terminated

Single Oral Dose of Bevenopran in Patients With Varying Degrees of Renal Impairment

Renal Impairment

United States
Eli Lilly and Company

Completed

A Single Dose Study of LY2189265 in Subjects With Varying Degrees of Hepatic (Liver) Impairment

Diabetes Mellitus, Type 2

Germany, Hungary
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Pharmacokinetics of PCI-32765 in Participants With Varying Degrees of Hepatic Impairment

Hepatic Impairment

United States
Medicure

Completed

Pharmacokinetic Evaluation of Tirofiban Using a Single High-Dose Bolus In Subjects With Varying Degrees of Renal Function

Renal Insufficiency

United States
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study to Assess the Pharmacokinetics, Pharmacodynamics, and Safety of Canagliflozin (JNJ-28431754) in Volunteers With Varying Degrees of Kidney Function

Healthy | Renal Insufficiency

United States
The University of Texas Health Science Center at...
National Cancer Institute (NCI); Lily Research Laboratories

Completed

LY231514 in Treating Patients With Locally Advanced or Metastatic Solid Tumors and Varying Degrees of Kidney Function

Unspecified Adult Solid Tumor, Protocol Specific

United States
Cephalon

Completed

A Study to Assess the Pharmacokinetics of the Hydrocodone Extended-Release Tablet (CEP-33237) in Subjects With Normal Renal Function and Subjects With Varying Degrees of Renal Impairment

Renal Impairment

United States
Novartis Pharmaceuticals

Completed

A Study of Patupilone in Patients With Advanced Solid Tumors and Varying Degrees of Hepatic Function

Advanced Malignancies | Tumors

United States
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study to Evaluate the Pharmacokinetics and Safety of Levofloxacin in Patients With Varying Degrees of Renal Function.

Renal Diseases
Karamanoğlu Mehmetbey University

Not yet recruiting

Determination of Salivary Soluble Urokinase Plasminogen Activator Receptor (SuPAR), Hypoxia-inducible Factor-1 Alpha (HIF-1α), E-cadherin, Galectin 3, IL-4, IL-10 and TNF-α Levels in Individuals With Different Degrees of Periodontal Disease

Periodontitis | Periodontal Diseases
Bristol-Myers Squibb

Not yet recruiting

Study to Assess Drug Levels and Safety of BMS-986278 in Healthy Participants and Participants With Different Degrees of Hepatic Impairment

Hepatic Impairment | Healthy Participants
VA Office of Research and Development
Northwestern University

Not yet recruiting

Movement Amplification Gait Training to Enhance Walking Balance Post-Stroke

Chronic Hemiparetic Stroke

United States
University of Vienna
Medical University of Vienna

Recruiting

Nutritional Modulation of Cognition and Brain Activity

Cognitive Change | Nutrition, Healthy | Brain Activity

Austria

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