Search clinical trials for: vytorin

Total 51 results

Organon and Co

Completed

A Multicenter, Randomized, Open Label Study to Evaluate the Lipid Lowering Efficacy and Safety of Vytorin® 10/20 vs. Atorvastatin 10mg in Hypercholesterolemia Patients With Metabolic Syndrome in Korea (0653A-129)(COMPLETED)

Hypercholesterolemia
Organon and Co

Completed

Ezetimibe/Simvastatin (MK-0653A) Versus Rosuvastatin Versus Doubling Statin Dose in Participants With Cardiovascular Disease and Diabetes Mellitus (MK-0653A-133)(COMPLETED)

Diabetes Mellitus | Cardiovascular Disorder
Organon and Co

Completed

A Study to Assess the Cholesterol Lowering Effect of an Ezetimibe/Simvastatin Combination Tablet Compared to Another Cholesterol Lowering Drug in Patients With High Cholesterol and With High Cardiovascular Risk (0653A-809)(COMPLETED)

Hypercholesterolemia
Organon and Co

Completed

Ezetimibe/Simvastatin (10 mg/40 mg) vs. the Doubling of Atorvastatin in High Risk Participants (MK-0653A-134 AM1)(COMPLETED)

Hypercholesterolemia
Organon and Co

Completed

Ezetimibe/Simvastatin in Patients With Metabolic Syndrome (0653A-107)(COMPLETED)

Metabolic Syndrome | Hypercholesterolemia
Organon and Co

Completed

Ezetimibe (+) Simvastatin vs. Atorvastatin Comparative Study in DM or Metabolic Syndrome Patients (0653A-093)

Hypercholesterolemia
University at Buffalo
Kaleida Health

Completed

To Study the Effect of Vytorin on Intracellular Lipid and Inflammation in Obese Subjects

Inflammation

United States
Baylor College of Medicine
Merck Sharp & Dohme LLC

Completed

Effects of Ezetimibe, Simvastatin, and Vytorin on Reducing L5 a Subfraction of LDL in Patients With Metabolic Syndrome. (Merck-123)

Metabolic Syndrome

United States
Cedars-Sinai Medical Center
Roswell Park Cancer Institute

Completed

Cellular Effect of Cholesterol-Lowering Prior to Prostate Removal

Prostate Cancer

United States
Amarin Pharma Inc.

Completed

Efficacy and Safety of AMR101 (Ethyl Icosapentate) in Patients With Fasting Triglyceride (Tg) Levels ≥ 500 and ≤ 2000 mg/dL (MARINE)

Hypertriglyceridemia

United States, Netherlands, Russian Federation, Ukraine, Denmark, Finland, Germany, India, Italy, Mexico, South Africa
Amarin Pharma Inc.

Completed

Effect of AMR101 (Ethyl Icosapentate) on Triglyceride (Tg) Levels in Patients on Statins With High Tg Levels (≥ 200 and < 500 mg/dL) (ANCHOR)

Hypertriglyceridemia

United States
Amarin Pharma Inc.

Completed

A Study of AMR101 to Evaluate Its Ability to Reduce Cardiovascular Events in High-Risk Patients With Hypertriglyceridemia and on Statin (REDUCE-IT)

Cardiovascular Diseases

United States, Australia, Canada, India, Netherlands, New Zealand, Poland, Romania, Russian Federation, South Africa, Ukraine
Organon and Co

Completed

Ezetimibe Plus (+) Simvastatin Versus Atorvastatin Comparative Study (0653A-092)(COMPLETED)

Hypercholesterolemia
Organon and Co

Completed

Begin With The Right Patients With Dual-Inhibition Action Therapy Through Vytorin for Newly Diagnosed Dyslipidemia Patients (0653A-172)(COMPLETED) (BRAVO)

Hypercholesterolemia
Organon and Co

Completed

Vytorin (10/20 Or 10/40) Compared to Atorvastatin (10 mg or 20 mg) in Patients With Coronary Artery Disease (0653A-126)(COMPLETED)

Hypercholesterolemia
Organon and Co

Completed

Vytorin As Strategy To Reduce Dislipidemia In Adults (0653A-148)

Hyperlipidemia
Organon and Co

Withdrawn

A Study to Evaluate the Efficacy and Safety of Vytorin Versus Standard Treatment of Other Statins in Moderate, Moderately High and High Risk Participants (MK-0653A-406) (VYCTORY)

Dyslipidemia
Organon and Co

Completed

EASEGO Study: Doubling of Atorvastatin/Simvastatin or INEGY in Patients With Hypercholesterolemia and Coronary Artery Disease(CAD)(0653A-089)

Atherosclerosis
Organon and Co

Terminated

Vytorin Treating Uncontrolled Lipids (VyTUL) Study (0653A-122)

Cardiovascular Diseases | Diabetes Mellitus
Organon and Co
Merck Sharp & Dohme LLC

Completed

Effect of Ezetimibe Plus Simvastatin Versus Simvastatin Alone on Atherosclerosis in the Carotid Artery (ENHANCE)(P02578) (ENHANCE)

Atherosclerosis | Hypercholesterolemia | Hyperlipoproteinemia Type II
Organon and Co
Merck Sharp & Dohme LLC

Completed

Assessment of Interaction Between Vytorin and Niaspan in Healthy Subjects (P04955AM2)

Hypercholesterolemia | Hyperlipidemia
Organon and Co

Completed

Vytorin Reexamination Study (0653A-174)

Primary Hypercholesterolemia and Homozygous Familial Hypercholesterolemia (HoFH)
Organon and Co
Merck Sharp & Dohme LLC; Schering-Plough

Completed

Effects of Vytorin Versus Placebo in Subjects With Primary Hypercholesterolemia (Study P04420)

Hypercholesterolemia
Organon and Co

Completed

IMPROVE-IT: Examining Outcomes in Subjects With Acute Coronary Syndrome: Vytorin (Ezetimibe/Simvastatin) vs Simvastatin (P04103)

Myocardial Infarction | Hypercholesterolemia
Organon and Co

Completed

Post-marketing Surveillance of the Safety, Tolerability and Efficacy of Vytorin (Ezetimibe + Simvastatin) Tablet Among Filipino Patients (Study P05647)

Hypercholesterolemia
University of Colorado, Denver
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Merck...

Completed

Clinical Trial of Zocor (Simvastatin) and Vytorin (Ezetimibe/Simvastatin) in Adolescents With Type 1 Diabetes

Dyslipidemia | Type 1 Diabetes Mellitus

United States
Institut de Médecine et d'Epidémiologie Appliquée...
Merck Sharp & Dohme LLC; Institut National de la Santé Et de la Recherche Médicale...

Completed

Short Duration Therapy of Acute Hepatitis C Genotypes 1 or 4 (SAHIV)

HIV | Acute Hepatitis C

France
Ache Laboratorios Farmaceuticos S.A.

Completed

Efficacy/Safety of Rosuvastatin+Ezetimibe in High Risk Patients With Primary Hypercholesterolemia/Mixed Dyslipidemia (LANCE)

Dyslipidemia | Hypercholesterolemia

Brazil
University of Maryland, Baltimore
Merck Sharp & Dohme LLC

Completed

Simvastatin With or Without Ezetimibe and Atherothrombotic Biomarker Assessment

Metabolic Syndrome

United States
Pfizer

Completed

Evaluation Of Acceptability And Satisfaction Of Hemophilia Patients Treated With FusENGO

Hemophilia A

Italy
Johns Hopkins University
National Institute on Aging (NIA)

Completed

High-Density Lipoprotein (HDL) Cholesterol Increased Plaque Stabilization in the Elderly (NIA-Plaque)

Cardiovascular Disease | Atherosclerosis

United States
University of Virginia
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health...

Completed

Comprehensive Magnetic Resonance of Peripheral Arterial Disease

Peripheral Artery Disease

United States
Complexa, Inc.

Completed

A Study of the PK Interaction of CXA-10 With Pravastatin and Vytorin® in Healthy Males (DDI)

Acute Kidney Injury

United States
Hospital Universitario 12 de Octubre
Merck Sharp & Dohme LLC

Completed

Vytorin on Carotid Intima-media Thickness and Overall Rigidity (VYCTOR)

Cardiovascular Diseases
Instituto Nacional de Ciencias Medicas y Nutricion...
Merck Sharp & Dohme LLC

Withdrawn

Efficacy of Ezetimibe/Simvastatin 10/20 mg and MK0524A (1-2 g/Day) in Mixed Hyperlipidemia and Two or More Risk Factors

Cardiovascular Diseases | Hyperlipidemia
Korea University

Withdrawn

Effects on Atherosclerosis Regression of Ezetimibe or Ezetimibe Plus Simvastatin; Evaluated by Fluorodeoxyglucose Positron Emission Tomography (FDG-PET)

Atherosclerosis

Korea, Republic of
University of Miami

Completed

Vytorin in the Treatment of Alopecia Areata

Alopecia Areata

United States
Gachon University Gil Medical Center

Completed

Vascular and Metabolic Effects of Vytorin vs Simvastatin

Hypercholesterolemia

Korea, Republic of
Gachon University Gil Medical Center

Completed

Vascular and Metabolic Effects of Vytorin

Hypercholesterolemia

Korea, Republic of
University of Guadalajara

Completed

Statins for Oxidative Stress and Mitochondrial Function in Diabetic Polyneuropathy

Oxidative Stress | Diabetic Polyneuropathy

Mexico
University of Oxford
Merck Sharp & Dohme LLC

Completed

Treatment of HDL to Reduce the Incidence of Vascular Events HPS2-THRIVE (HPS2-THRIVE)

Cardiovascular Disease | Diabetes Mellitus | Peripheral Arterial Disease | Coronary Heart Disease

United Kingdom
Yonsei University

Completed

Early Effects of Intensive Lipid Lowering Treatment With Ezetimibe/ Simvastatin (Vytorin®) Assessed by Virtual Histology-Intravascular Ultrasound (VH-IVUS) and Optical Coherence Tomography (OCT) on Plaque Characteristics in Patients With Acute Coronary Syndrome

Acute Coronary Syndrome

Korea, Republic of
Fundación Lindavista del Corazón AC

Terminated

Left Ventricular Hypertrophy Reduction With Statins in Hypertensives Patients (MK0653A-168)

Hypertension
Bronx VA Medical Center

Completed

Comparison of the Effect of Vytorin 10/80 Tablet Split Into 4 and Simvastatin 20 Milligrams on Low-density Lipoprotein (LDL) Cholesterol

Hypercholesterolemia

United States
University of Oxford
National Health and Medical Research Council, Australia; Merck Sharp & Dohme... and other collaborators

Completed

Study of Heart and Renal Protection (SHARP)

Kidney Disease, Chronic

United Kingdom
Federal University of Bahia
Escola Bahiana de Medicina e Saude Publica

Unknown

Pleiotropism of Statin Therapy in High Dose Versus Low Dose Combined With Ezetimibe

Endothelial Function

Brazil
Seoul National University Hospital
Merck Sharp & Dohme LLC

Unknown

Study to Compare the Effect of Vytorin (Simvastatin/Ezetimibe) 10/20mg Versus Atorvastatin 20mg on ApoB/ApoA1 Ratio in Subjects With Diabetes

Type 2 Diabetes Mellitus Without Insulin Treatment

Korea, Republic of
University of Sao Paulo

Completed

Antiplatelet and Anti-inflammatory Effects of Statins and Ezetimibe

Stable Angina

Brazil
Brasilia Heart Study Group

Completed

Additive Effect of Ezetimibe Upon Simvastatin During Myocardial Infarction

Myocardial Infarction

Brazil
National Cheng-Kung University Hospital

Completed

Vascular Effects of Ezetimibe/Simvastatin and Simvastatin on Atherosclerosis

Atherosclerosis

Taiwan

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