Search clinical trials for: watch and wait

Total 472228 results

Children's Oncology Group

Not yet recruiting

A Study Using Risk Factors to Determine Treatment for Children With Favorable Histology Wilms Tumors (FHWT)

Stage I Kidney Wilms Tumor | Stage II Kidney Wilms Tumor | Stage III Kidney Wilms Tumor | Stage IV Kidney Wilms Tumor
M.G. Besselink

Recruiting

Preventing Recurrent 'Idiopathic' Acute Pancreatitis Through Laparoscopic Cholecystectomy (PICUS-2) (PICUS-2)

Idiopathic Acute Pancreatitis

Netherlands
Fudan University
Shanghai Zhongshan Hospital; RenJi Hospital; First Hospital of China Medical... and other collaborators

Not yet recruiting

Organ Preservation With Tislelizumab and Total Neoadjuvant Therapy in Patients With Low Rectal Cancer: RELIEVE -01 Study

Rectal Cancer | RECTAL NEOPLASMS
Mayo Clinic

Not yet recruiting

Stereotactic Body Radiation Therapy Plus Androgen Receptor Pathway Inhibitor and Androgen Deprivation Therapy for Treatment of Metastatic, Recurrent Hormone-Sensitive Prostate Cancer, DIVINE Trial (DIVINE)

Recurrent Prostate Cancer | Castration-resistant Prostate Cancer | Stage IVB Prostate Cancer AJCC v8 | Recurrent Castration-Sensitive Prostate Carcinoma

United States
Tampere University Hospital
Turku University Hospital; Helsinki University Central Hospital; Oulu University... and other collaborators

Recruiting

Nordic ORgan Preservation Pilot Approach Nonrandomised Single-Arm Trial for Non-Operative Management of Rectal Cancer (NORPPA-1)

Rectal Cancer | Rectal Adenocarcinoma

Finland, Estonia
Tata Memorial Centre

Not yet recruiting

Study for Wait and Watch Suitable in Rectal Cancer (ARROW)

Rectal Neoplasms
Academic and Community Cancer Research United

Not yet recruiting

Epcoritamab Compared to Observation for Treating B-cell Lymphoma Patients Not in Complete Remission After CD19-directed CAR-T Therapy

Primary Mediastinal Large B-Cell Lymphoma | Diffuse Large B-Cell Lymphoma, Not Otherwise Specified | Transformed Indolent B-Cell Non-Hodgkin Lymphoma to Diffuse Large B-Cell Lymphoma

United States
Peking University Cancer Hospital & Institute

Recruiting

Organ Preservation First Strategy and Intentional Watch and Wait for MRI Defined Low-risk Rectal Cancer

Rectal Cancer

China
Jinhua Central Hospital

Not yet recruiting

Node-sparing Radiotherapy Combined With Total Neoadjuvant CAPOX and Sintilimab for MSS Middle and Low Rectal Cancer (CASINOs)

Locally Advanced Rectal Cancer

China
University Hospital, Strasbourg, France
Direction Générale de l'Offre des Soins (DGOS)

Recruiting

Cryoablation Versus Medical Therapy in Desmoid Tumors Progressing After Watchful Waiting (CRYODESMO-02)

Desmoid Tumor

France
GERCOR - Multidisciplinary Oncology Cooperative...

Recruiting

Watch-and-Wait Approach With Dostarlimab in Localized dMMR/MSI-H Gastric Cancer: GERCOR Phase II Study (DEWI)

Gastric Adenocarcinoma | Adenocarcinoma - GEJ

France
Osaka University

Recruiting

A Multicenter Single-arm P2 to Evaluate Safety and Efficacy of the Total Neoadjuvant Therapy for cT2 Rectal Cancer (AMBITION)

Rectal Cancer

Japan
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Recruiting

Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab

Anatomic Stage I Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage III Breast Cancer AJCC v8 | Early Stage Triple-Negative Breast Carcinoma

United States, Puerto Rico
NeoTract, Inc.

Not yet recruiting

RELIEF Study: Real-world Evaluation of LUTS Interventions and Patient Experience During Follow-up (RELIEF)

Benign Prostatic Hyperplasia
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Recruiting

Testing the Use of BRAF-Targeted Therapy After Surgery and Usual Chemotherapy for BRAF-Mutated Colon Cancer

Stage III Colon Cancer AJCC v8 | Colon Adenocarcinoma | Microsatellite Stable Colon Carcinoma | Stage IIB Colon Cancer AJCC v8 | Stage IIC Colon Cancer AJCC v8

United States
SWOG Cancer Research Network
National Cancer Institute (NCI); Genentech, Inc.

Recruiting

Testing Drug Treatments After CAR T-cell Therapy in Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma

Diffuse Large B-Cell Lymphoma | Recurrent Diffuse Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Grade 3b Follicular Lymphoma | Transformed Follic Lymph to Diff Large B-Cell Lymphoma | Transformed Marg Zone Lymph to Diff...

United States
Ascension South East Michigan

Recruiting

Watchful Waiting for Complete Responders to Therapy in Rectal Cancer

Rectal Cancer

United States
Rutgers, The State University of New Jersey
New Jersey Governor's Council for Medical Research and Treatment of Autism

Recruiting

Transdiagnostic Group Therapy (GBAT) for Autistic Adults With Personalized Therapeutics ((GBAT+))

GBAT+Individual | GBAT+Engagement Booster | GBAT+Both

United States
Zhejiang Cancer Hospital
Jiangsu HengRui Medicine Co., Ltd.

Recruiting

Watch and Wait for NeoAdjuvant Concurrent Radiochemotherapy Combined With Camrelizumab in Patients With Resectable ESCC (WATCHER)

Esophageal Squamous Cell Carcinoma

China
Na Homolce Hospital
Centre of Cardiovascular and Transplantation Surgery, Czech Republic; St. Anne... and other collaborators

Recruiting

Early Aortic vaLve surgEry Versus wAtchful waitiNg Strategy in Severe Asymptomatic aOrtic reguRgitation (ELEANOR)

Aortic Valve Regurgitation

Serbia, Czechia, Belgium
Azienda Ospedaliero-Universitaria Careggi
Società Italiana di Urologia (SIU); Italian Group for Advanced Laparo-Endoscopic...

Recruiting

International REgistry of COnservative or Radical Treatment of Localized Kidney Tumors (i-RECORd)

Kidney Cancer

Italy, United States, Spain, United Kingdom, Belgium, Austria, Brazil, Greece, Japan, Netherlands, Poland, Russian Federation, Singapore
Sun Yat-sen University

Recruiting

Watch and Wait Versus Surgical Treatment for Clinical Complete Responders After Non-Curative Therapy for Hepatocellular Carcinoma (WATCH)

Hepatocellular Carcinoma

China
Lund University

Recruiting

Effect of Ventilation Tubes in Otitis-prone Children

Recurrent Acute Otitis Media

Sweden
University Hospital, Ghent

Recruiting

RCT Treatment Versus Non Treatment of Low-risk BCCs in Elderly (BASINEL)

Elderly | Basal Cell Carcinoma

Belgium
Hospital Israelita Albert Einstein
Ministry of Health, Brazil

Recruiting

Brazilian Total Neoadjuvant Therapy Trial (BRAZIL-TNT)

Colorectal Neoplasms

Brazil
National Cancer Institute (NCI)

Recruiting

Evaluating the Addition of the Immunotherapy Drug Atezolizumab to Standard Chemotherapy Treatment for Advanced or Metastatic Neuroendocrine Carcinomas That Originate Outside the Lung

Advanced Extrapulmonary Neuroendocrine Carcinoma | Metastatic Extrapulmonary Neuroendocrine Carcinoma | Recurrent Extrapulmonary Neuroendocrine Carcinoma | Unresectable Extrapulmonary Neuroendocrine Carcinoma

United States
Hospital Alemão Oswaldo Cruz

Recruiting

Chemoradiation and Consolidation Chemotherapy With or Without Oxaliplatin for Distal Rectal Cancer and Watch and Wait (CCHOWW)

Rectal Cancer | Consolidation

Brazil, Argentina, Uruguay
Beijing Chao Yang Hospital

Recruiting

Multi-points and Full-thickness Biopsy in the Diagnosis of cCR After Neoadjuvant Therapy for Rectal Cancer (BIOPSY)

Rectal Cancer | Metastasis | Neoadjuvant Therapy | Complete Remission

China
Kangbuk Samsung Hospital

Recruiting

Non-OpeRative MANagement of Rectal Cancer Patients (NORMANDY)

Rectal Cancer | Chemoradiotherapy | Watch & Wait

Korea, Republic of
Sixth Affiliated Hospital, Sun Yat-sen University

Recruiting

Watch and Wait in PD-1 Monoclonal Antibody Treated dMMR/MSI-H Distal Rectal Cancer (BASKET)

Rectal Cancer

China
Maastricht University Medical Center
Dutch Heart Foundation; ZonMw: The Netherlands Organisation for Health Research... and other collaborators

Recruiting

Device-based Rate Versus Rhythm Control in Symptomatic Recent-onset Atrial Fibrillation (RACE 9 OBSERVE-AF)

Atrial Fibrillation

Netherlands
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

White Button Mushroom Sup for the Reduction of PSA in Pts With Biochemically Rec or Therapy Naive Fav Risk Prostate CA

Prostate Adenocarcinoma | Recurrent Prostate Carcinoma | Stage I Prostate Cancer AJCC v8 | Stage IIIA Prostate Cancer AJCC v8 | Stage IIC Prostate Cancer AJCC v8 | Stage IIIC Prostate Cancer AJCC v8 | PSA Failure | PSA Progression | Stage IIA Prostate Cancer AJCC v8 | Stage IIB Prostate Cancer AJCC v8

United States
BioNTech SE
Genentech, Inc.

Recruiting

A Phase II Clinical Trial Comparing the Efficacy of RO7198457 Versus Watchful Waiting in Patients With ctDNA-positive, Resected Stage II (High Risk) and Stage III Colorectal Cancer

Colorectal Cancer Stage II | Colorectal Cancer Stage III

United States, Spain, United Kingdom, Germany, Belgium, Sweden
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Recruiting

Using Biomarkers to Help Guide Safe Immunotherapy Discontinuation in Patients With Unresectable Stage IIIB-IV Melanoma, The PET-Stop Trial

Unresectable Melanoma | Clinical Stage III Cutaneous Melanoma AJCC v8 | Melanoma of Unknown Primary | Pathologic Stage IIIB Cutaneous Melanoma AJCC v8 | Pathologic Stage IIIC Cutaneous Melanoma AJCC v8 | Pathologic Stage IIID Cutaneous Melanoma AJCC v8 | Clinical Stage IV Cutaneous Melanoma AJCC... and other conditions

United States
Fudan University

Not yet recruiting

An Adaptive-design Prospective Cohort Study of Watch and Wait Strategy in Patients With Locally Advanced Rectal Cancer

Rectal Cancer

China
Peking University Cancer Hospital & Institute

Recruiting

Total Neoadjuvant Therapy Followed by 'Watch and Wait' Approach or Organ Preservation for Low-risk Rectal Cancer (BJCC-R01)

Rectum Cancer

China
Sir Mortimer B. Davis - Jewish General Hospital
Icad, Inc.

Recruiting

Watch and Wait Management on Rectal Cancer Patients Using New Swift Local Therapy (Whistle)

Rectal Cancer | Inoperable Disease | Comorbidities and Coexisting Conditions | Brachytherapy

Canada
Sun Yat-sen University

Recruiting

Pd1 Antibody Sintilimab ± Chemoradiotherapy for Locally Advanced Rectal Cancer

Colorectal Cancer Stage II | Colorectal Cancer Stage III | MSI-H | Mmr Deficiency

China
Maria Sklodowska-Curie National Research Institute...
Polish Society of Surgical Oncology

Recruiting

Organ-preserving Management in Patients With Complete or Near-complete Tumour Response After Preoperative Radio(Chemo)Therapy for Rectal Cancer

Rectal Cancer | Rectal Neoplasms

Poland
Carmel Medical Center

Not yet recruiting

Treatment of Juvenile Recurrent Parotitis: the Yield of Minimally Invasive Intervention (JRP)

Parotitis, Juvenile Recurrent

Israel
UMC Utrecht
Maastricht University Medical Center; Academisch Medisch Centrum - Universiteit... and other collaborators

Recruiting

Dutch-AMR: Early Mitral Valve Repair Versus Watchful Waiting in Asymptomatic Patients With Severe Mitral Regurgitation (Dutch-AMR)

Mitral Regurgitation

Netherlands
National Cancer Institute (NCI)

Recruiting

Testing Immunotherapy Versus Observation in Patients With HPV Throat Cancer

Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Pathologic Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Pathologic Stage III HPV-Mediated (p16-Positive)...

United States
Sixth Affiliated Hospital, Sun Yat-sen University

Recruiting

Adjuvant Chemotherapy in Clinical Local Advanced CRC Following Preoperational Therapies and pT0-3N0M0 Diagnosis (CANWATCH)

Colorectal Cancer | Adjuvant Chemotherapy

China
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Active Surveillance and Chemotherapy Before Surgery in Treating Participants With Stage II-III Rectal Cancer

Stage III Rectal Cancer AJCC v8 | Stage IIIA Rectal Cancer AJCC v8 | Stage IIIB Rectal Cancer AJCC v8 | Stage IIIC Rectal Cancer AJCC v8 | Rectal Adenocarcinoma | Stage IIA Rectal Cancer AJCC v8 | Stage IIB Rectal Cancer AJCC v8 | Stage II Rectal Cancer AJCC v8 | Stage IIC Rectal Cancer AJCC v8

United States
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

Acalabrutinib With or Without Obinutuzumab in Treating Patients With Early-Stage Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Chronic Lymphocytic Leukemia | Small Lymphocytic Lymphoma

United States
The Netherlands Cancer Institute
Dutch Cancer Society

Recruiting

"Wait-and-see" Policy for Complete Responders After Chemoradiotherapy for Rectal Cancer

Rectal Neoplasms

Netherlands, Belgium
SWOG Cancer Research Network
National Cancer Institute (NCI)

Recruiting

S1501 Carvedilol in Preventing Cardiac Toxicity in Patients With Metastatic HER-2-Positive Breast Cancer

Cardiotoxicity | Recurrent Breast Carcinoma | HER2/Neu Positive | Metastatic Malignant Neoplasm in the Brain | Stage IV Breast Cancer AJCC v6 and v7

United States, Korea, Republic of, Puerto Rico, Saudi Arabia
Centre Hospitalier Universitaire, Amiens

Recruiting

Early Mitral ValvE Repair Versus Watchful Waiting for Asymptomatic SEvere Degenerative Mitral Regurgitation (REVERSE-MR)

Degenerative Mitral Regurgitation (MR) Due to Leaflet Prolapse

France
National Cancer Institute (NCI)

Recruiting

Clonal Evolution in Follicular Lymphoma

Follicular Lymphoma

United States
Johns Hopkins University
United States Department of Defense

Recruiting

Tesamorelin to Improve Functional Outcomes After Peripheral Nerve Injury

Peripheral Nerve Injuries

United States

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