- ICH GCP
- US Clinical Trials Registry
- Klinisk forsøg NCT01458834
Attentional Training for Smoking Cessation Via Handheld Device or Personal Computer
27. juli 2026 opdateret af: Boston University Charles River Campus
Several studies indicate that cigarette smokers show an attentional bias for cigarette-related cues, meaning that they more quickly detect and attend to and have more difficulty disengaging in cigarette-related information than neutral information.
This bias is associated with craving and relapse following attempts to quit.
This experiment will examine whether a computerized attentional training procedure will successfully reduce attentional bias towards smoking cues and reduce craving in regular cigarette smokers.
The attentional training will be administered in a novel format in which participants complete 5-minute long training sessions 3 times per day and can complete the trainings via home computer or handheld device such as the iPhone, Android phone, or iPod touch.
A baseline assessment in the laboratory will measure attentional bias to smoking cues and craving following smoking cue exposure.
Participants will then be randomly assigned to either the active training condition or a control condition.
In both conditions, participants will be asked to complete brief training sessions 3 times daily for one week using their personal computer or handheld device.
Following one week of training, participants will return to the lab for endpoint assessment of attentional bias and craving.
The investigators hypothesize that compared to the control condition, the active training condition will significantly reduce attentional bias toward smoking related cues and cue-induced cigarette craving.
Studieoversigt
Status
Afsluttet
Betingelser
Intervention / Behandling
Undersøgelsestype
Interventionel
Tilmelding (Faktiske)
60
Fase
- Ikke anvendelig
Kontakter og lokationer
Dette afsnit indeholder kontaktoplysninger for dem, der udfører undersøgelsen, og oplysninger om, hvor denne undersøgelse udføres.
Studiesteder
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Massachusetts
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Boston, Massachusetts, Forenede Stater, 02215
- Boston University Charles River Campus
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Deltagelseskriterier
Forskere leder efter personer, der passer til en bestemt beskrivelse, kaldet berettigelseskriterier. Nogle eksempler på disse kriterier er en persons generelle helbredstilstand eller tidligere behandlinger.
Berettigelseskriterier
Aldre berettiget til at studere
18 år og ældre (Voksen, Ældre voksen)
Tager imod sunde frivillige
Ingen
Beskrivelse
Inclusion Criteria:
- Age 18-65.
- Familiarity with a computer keyboard and mouse.
- Must own a iPhone, iPod Touch, or Google Android-based phone (such as the Droid or Nexus One) or have regular access to the Internet via personal computer.
- Current regular smoker, as defined by self-reported use of at least 1 year and a current average of at least 10 cigarettes smoked per day.
Exclusion Criteria:
1. Individuals with current suicidality (determined by a score of 2 or 3 on item 9 of the Beck Depression Inventory given following consent) will be excluded from further participation.
Studieplan
Dette afsnit indeholder detaljer om studieplanen, herunder hvordan undersøgelsen er designet, og hvad undersøgelsen måler.
Hvordan er undersøgelsen tilrettelagt?
Design detaljer
- Primært formål: Behandling
- Tildeling: Randomiseret
- Interventionel model: Parallel tildeling
- Maskning: Dobbelt
Våben og indgreb
Deltagergruppe / Arm |
Intervention / Behandling |
|---|---|
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Eksperimentel: Active attention training condition
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Participants will complete a computerized probe-discrimination task from their home computer or handheld electronic device 3 times per day for one week.
Each training session will consist of 160 trials.
In each trial, two pictures (smoking-related or neutral) will appear on the screen simultaneously and then disappear.
An arrow will appear in the location of one of the pictures (< or >).
Participants are asked to quickly identify the direction of the arrow by pressing a button.
In the active training task, the arrow will replace the neutral pictures 80% of the time.
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Placebo komparator: Kontroltilstand
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Participants will complete a computerized probe-discrimination task from their home computer or handheld electronic device 3 times per day for one week.
Each training session will consist of 160 trials.
In each trial, two pictures (smoking-related or neutral) will appear on the screen simultaneously and then disappear.
An arrow will appear in the location of one of the pictures (< or >).
Participants are asked to quickly identify the direction of the arrow by pressing a button.
In the control training task, the arrow will replace the neutral and smoking-related pictures with equal frequency.
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Hvad måler undersøgelsen?
Primære resultatmål
Resultatmål |
Tidsramme |
|---|---|
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Brief Questionnaire of Smoking Urges (QSU-Brief)
Tidsramme: Assessed at baseline and endpoint visits (one week apart)
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Assessed at baseline and endpoint visits (one week apart)
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Attentional Bias Scores
Tidsramme: Assessed at baseline and endpoint visits (one week apart)
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Assessed at baseline and endpoint visits (one week apart)
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Samarbejdspartnere og efterforskere
Det er her, du vil finde personer og organisationer, der er involveret i denne undersøgelse.
Samarbejdspartnere
Efterforskere
- Ledende efterforsker: Samantha Moshier, MA, Boston University Charles River Campus
Datoer for undersøgelser
Disse datoer sporer fremskridtene for indsendelser af undersøgelsesrekord og resumeresultater til ClinicalTrials.gov. Studieregistreringer og rapporterede resultater gennemgås af National Library of Medicine (NLM) for at sikre, at de opfylder specifikke kvalitetskontrolstandarder, før de offentliggøres på den offentlige hjemmeside.
Studer store datoer
Studiestart
1. september 2011
Primær færdiggørelse (Faktiske)
1. december 2012
Studieafslutning (Faktiske)
1. december 2012
Datoer for studieregistrering
Først indsendt
22. oktober 2011
Først indsendt, der opfyldte QC-kriterier
22. oktober 2011
Først opslået (Anslået)
25. oktober 2011
Opdateringer af undersøgelsesjournaler
Sidste opdatering sendt (Faktiske)
29. juli 2026
Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier
27. juli 2026
Sidst verificeret
1. oktober 2011
Mere information
Begreber relateret til denne undersøgelse
Nøgleord
Andre undersøgelses-id-numre
- BU-2453
Plan for individuelle deltagerdata (IPD)
Planlægger du at dele individuelle deltagerdata (IPD)?
INGEN
Disse oplysninger blev hentet direkte fra webstedet clinicaltrials.gov uden ændringer. Hvis du har nogen anmodninger om at ændre, fjerne eller opdatere dine undersøgelsesoplysninger, bedes du kontakte register@clinicaltrials.gov. Så snart en ændring er implementeret på clinicaltrials.gov, vil denne også blive opdateret automatisk på vores hjemmeside .