Estrogen and the Outer Eye in Women During Fertility Treatment
The Influence of the Hormonal Fertility Treatment of Women, on the Eye Surface and the Eye Dryness
Studieoversigt
Status
Betingelser
Detaljeret beskrivelse
Women during their fertility treatments will be submitted to the research. The research will include 3 meetings with a doctor from the ophthalmology department. Each meeting will be individual for each participant of the research.
The meetings will take place during the day of regular appointment of the participant to the fertility clinic.
Meeting #1:
During first visit to the fertility clinic for the stimulation process.
During this day will be done:
1.Submission of the patient to the research and signing on letter of agreement 2.Blood tests for estrogen, progesterone, luteinizing hormone (LH) 3.Eye examination: 3a. Filling of Schein Questionnaire 3b. Examination of the external eye: 1.microscope, 2.Schirmer test (paper strips inserted into the eye for several minutes to measure the production of tears), 3. tear break up time test (checking the eye with the fluorescein light after painting the eye with fluorescein dye) 3c. Checking the Intra Ocular Pressure with Tonometer
Meeting #2:
During visit to the fertility clinic for the egg collection (about 10 days after meeting #1)
During this day will be done:
1.Blood tests for estrogen, progesterone, luteinizing hormone (LH) 2.Eye examination: 2a. Filling of Schein Questionnaire 2b. Examination of the external eye: 1.microscope, 2.Schirmer test (paper strips inserted into the eye for several minutes to measure the production of tears), 3. tear break up time test (checking the eye with the fluorescein light after painting the eye with fluorescein dye) 2c. Checking the Intra Ocular Pressure with Tonometer
Meeting #3:
During visit to the fertility clinic for the pregnancy test (about 14 days after meeting #2)
During this day will be done:
- Blood tests for estrogen, progesterone, luteinizing hormone (LH)
- Eye examination:
2a. Filling of Schein Questionnaire 2b. Examination of the external eye: 1.microscope, 2.Schirmer test (paper strips inserted into the eye for several minutes to measure the production of tears), 3. tear break up time test (checking the eye with the fluorescein light after painting the eye with fluorescein dye) 2c. Checking the Intra Ocular Pressure with Tonometer
Collection and summary of all the data End of the research
Undersøgelsestype
Tilmelding (Forventet)
Deltagelseskriterier
Berettigelseskriterier
Aldre berettiget til at studere
Tager imod sunde frivillige
Køn, der er berettiget til at studere
Prøveudtagningsmetode
Studiebefolkning
Beskrivelse
Inclusion Criteria:
- women during fertility treatment
- without any known eye diseases
- no current or past history of treatment against dry eye
Exclusion Criteria:
- known eye disease
- current or past history of treatment against dry eye
Studieplan
Hvordan er undersøgelsen tilrettelagt?
Design detaljer
Kohorter og interventioner
Gruppe / kohorte |
|---|
|
women during fertility treatment
|
Hvad måler undersøgelsen?
Primære resultatmål
Resultatmål |
Tidsramme |
|---|---|
|
Evidence of clinically definite dry eye confirmed by Schirmer test and tear break up time test
Tidsramme: 24 days
|
24 days
|
Sekundære resultatmål
Resultatmål |
Tidsramme |
|---|---|
|
Evidence of clinically definite dry eye confirmed by Schirmer test and tear break up time test during each on of the meetings #1,#2 (day 0, day 10)
Tidsramme: 0 days, 10 days
|
0 days, 10 days
|
Samarbejdspartnere og efterforskere
Sponsor
Datoer for undersøgelser
Studer store datoer
Studiestart
Primær færdiggørelse (Forventet)
Studieafslutning (Forventet)
Datoer for studieregistrering
Først indsendt
Først indsendt, der opfyldte QC-kriterier
Først opslået (Skøn)
Opdateringer af undersøgelsesjournaler
Sidste opdatering sendt (Skøn)
Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier
Sidst verificeret
Mere information
Begreber relateret til denne undersøgelse
Nøgleord
Yderligere relevante MeSH-vilkår
Andre undersøgelses-id-numre
- EOEDFT-2
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