"Holding-cuddling" Plus Oral Sucrose Versus Oral Sucrose for Reducing Venipuncture Pain in Newborns and Infants (Casa)
"Holding-cuddling" plus oral sucrose versus oral sucrose for reducing venipuncture pain in newborns and infants.
Neonates and infants routinely undergo venipuncture in pediatric and neonatal intensive care units.
Such procedure is painful and several units administer 24% oral sucrose with pacifier during venipuncture, as this non-pharmacological intervention is considered safe and effective for procedural pain relief in infants from birth to 3 months of age. However, several studies point out that further research is needed to assess its efficacy in combination with other behavioral interventions for analgesia during painful procedures. Current knowledge suggests that multisensorial stimulation associated with oral sucrose could allow even more effective analgesia. To date, the studied stimulation strategies are based on massage, voice, eye contact and fragrance during heel prick. The "holding-cuddling" - that is the fact of holding the child in a safe, reassuring and warm position during the examination or medical intervention is promoted by various hospitals in order to favor the comfort of all the caregivers during such a procedures. This intervention should be primarily parents-driven but, in case of unavailability, it can be performed by the nursing staff. The hypothesis of this study is that the combination of "holding-cuddling" plus oral sucrose in more effective than oral sucrose in diminishing behavioral pain response during a venipuncture in newborns or infants less than three-month-old.
Studieoversigt
Status
Betingelser
Intervention / Behandling
Undersøgelsestype
Tilmelding (Faktiske)
Fase
- Ikke anvendelig
Deltagelseskriterier
Berettigelseskriterier
Aldre berettiget til at studere
Tager imod sunde frivillige
Køn, der er berettiget til at studere
Beskrivelse
Inclusion Criteria:
- Hospitalization at CHU de la Réunion - site sud in Neonatal Intensive Care Unit or Neonatology Unit. (Neonate reanimation, pediatric reanimation or Neonatology services)
- Informed consent from holder(s) of the parental authority
Exclusion Criteria:
- Intubated ou sedated patients
- Treated with a combined analgesic during venipuncture
- Having indications against sucrose
- For which behavorial items from DAN scale are difficult to evaluate regarding their pathology (ex: severe neuromotor handicap)
Studieplan
Hvordan er undersøgelsen tilrettelagt?
Design detaljer
- Primært formål: Andet
- Tildeling: Randomiseret
- Interventionel model: Parallel tildeling
- Maskning: Ingen (Åben etiket)
Våben og indgreb
Deltagergruppe / Arm |
Intervention / Behandling |
|---|---|
|
Eksperimentel: Holding-cuddling + Sucrose
The Holding-cuddling is started 5 minutes before and the sucrose administration is started 2 minutes before blood sampling.
|
The "Holding-cuddling" is started 5 minutes before veinipuncture.
The sucrose adminstration is started 2 minutes before veinipuncture.
|
|
Aktiv komparator: Sucrose alone
The sucrose administration is started 2 minutes before blood sampling.
|
The sucrose adminstration is started 2 minutes before veinipuncture.
|
Hvad måler undersøgelsen?
Primære resultatmål
Resultatmål |
Foranstaltningsbeskrivelse |
Tidsramme |
|---|---|---|
|
Evolution of Pain
Tidsramme: At 0 and 30 seconds after the veinopuncture
|
Measure of pain by DAN scale at the time of the veinopuncture
|
At 0 and 30 seconds after the veinopuncture
|
Sekundære resultatmål
Resultatmål |
Foranstaltningsbeskrivelse |
Tidsramme |
|---|---|---|
|
Cardiac Frequency
Tidsramme: At 0 and 30 seconds after veinopuncture
|
Measure of the cardiac frequency at the time of the veinopuncture and 30 seconds after
|
At 0 and 30 seconds after veinopuncture
|
|
Oxygen saturation
Tidsramme: At 0 and 30 seconds after veinopuncture
|
Measure of the oxygen saturation at the time of the veinopuncture and 30 seconds after
|
At 0 and 30 seconds after veinopuncture
|
|
Pain at 1 min
Tidsramme: 1 min after veinopincture
|
Measure of pain by DAN scale 1 minute after veinopuncture
|
1 min after veinopincture
|
Samarbejdspartnere og efterforskere
Efterforskere
- Ledende efterforsker: Francesco BONSANTE, MD, CHU de la réunion
- Ledende efterforsker: Silvia IACOBELLI, MD, CHU de la réunion
Datoer for undersøgelser
Studer store datoer
Studiestart (Faktiske)
Primær færdiggørelse (Faktiske)
Studieafslutning (Faktiske)
Datoer for studieregistrering
Først indsendt
Først indsendt, der opfyldte QC-kriterier
Først opslået (Skøn)
Opdateringer af undersøgelsesjournaler
Sidste opdatering sendt (Faktiske)
Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier
Sidst verificeret
Mere information
Begreber relateret til denne undersøgelse
Andre undersøgelses-id-numre
- 2015/CHU/08
Plan for individuelle deltagerdata (IPD)
Planlægger du at dele individuelle deltagerdata (IPD)?
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