Laser vs Lontophoresis in KOA
18. juni 2026 opdateret af: Abdulaziz Fahad Ahmed Alsulaimani, Kafrelsheikh University
Effectiveness of Laser Therapy Versus Lontophoresis in the Management of Knee Osteoarthritis: A Randomized Controlled Trial
This randomized controlled trial aims to compare the effectiveness of laser therapy and iontophoresis in patients with knee osteoarthritis.
The study will evaluate pain reduction, functional improvement, and knee joint mobility following
Studieoversigt
Status
Ikke rekrutterer endnu
Betingelser
Intervention / Behandling
Detaljeret beskrivelse
Participants will be randomly assigned into three groups receiving either laser therapy plus conventional physiotherapy, iontophoresis plus conventional physiotherapy, or conventional physiotherapy alone.
Outcome measures will be assessed before and after treatment
Undersøgelsestype
Interventionel
Tilmelding (Anslået)
66
Fase
- Ikke anvendelig
Kontakter og lokationer
Dette afsnit indeholder kontaktoplysninger for dem, der udfører undersøgelsen, og oplysninger om, hvor denne undersøgelse udføres.
Studiekontakt
- Navn: abdulaziz fahad alsulaimani, MASTER
- Telefonnummer: 966566613748
- E-mail: azoztaif88@hotmail.com
Deltagelseskriterier
Forskere leder efter personer, der passer til en bestemt beskrivelse, kaldet berettigelseskriterier. Nogle eksempler på disse kriterier er en persons generelle helbredstilstand eller tidligere behandlinger.
Berettigelseskriterier
Aldre berettiget til at studere
- Voksen
- Ældre voksen
Tager imod sunde frivillige
Ingen
Beskrivelse
Inclusion Criteria:
* Age 45-65 years.
- Diagnosed primary knee osteoarthritis (Grade I-II).
- Both genders.
- Ability to follow treatment protocol.
Exclusion Criteria:
* Previous knee surgery.
- Intra-articular injections within last 6 months.
- Pacemaker.
- Skin lesions at treatment area.
- Severe neurological or cardiovascular disorders.
Studieplan
Dette afsnit indeholder detaljer om studieplanen, herunder hvordan undersøgelsen er designet, og hvad undersøgelsen måler.
Hvordan er undersøgelsen tilrettelagt?
Design detaljer
- Primært formål: Behandling
- Tildeling: Randomiseret
- Interventionel model: Parallel tildeling
- Maskning: Enkelt
Våben og indgreb
Deltagergruppe / Arm |
Intervention / Behandling |
|---|---|
|
Aktiv komparator: Group A:
Low-Level Laser Therapy
|
Low-level laser therapy combined with conventional physical therapy for patients with knee osteoarthritis to reduce pain and improve functional mobility and knee joint range of motion
Conventional physical therapy program for patients with knee osteoarthritis including therapeutic exercises, stretching, strengthening exercises, and pain relief modalities to improve knee function and mobility.
|
|
Aktiv komparator: Group B
Iontophoresis
|
Conventional physical therapy program for patients with knee osteoarthritis including therapeutic exercises, stretching, strengthening exercises, and pain relief modalities to improve knee function and mobility.
Iontophoresis using dexamethasone combined with conventional physical therapy for patients with knee osteoarthritis to reduce pain and improve physical function and knee joint mobility
|
|
Aktiv komparator: Group C
Conventional Physical Therapy Only
|
Conventional physical therapy program for patients with knee osteoarthritis including therapeutic exercises, stretching, strengthening exercises, and pain relief modalities to improve knee function and mobility.
|
Hvad måler undersøgelsen?
Primære resultatmål
Resultatmål |
Tidsramme |
|---|---|
|
Pain intensity measured using Visual Analogue Scale (VAS)
Tidsramme: Baseline and after 4 weeks of treatment
|
Baseline and after 4 weeks of treatment
|
|
Functional disability measured using WOMAC.
Tidsramme: Baseline and after 4 weeks of treatment
|
Baseline and after 4 weeks of treatment
|
|
3. Knee Range of Motion (ROM).
Tidsramme: Baseline and after 4 weeks of treatment
|
Baseline and after 4 weeks of treatment
|
Sekundære resultatmål
Resultatmål |
Foranstaltningsbeskrivelse |
Tidsramme |
|---|---|---|
|
Change in physical function assessed by the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) Physical Function Subscale
Tidsramme: Baseline (Day 0) and Week 4
|
The WOMAC Physical Function Subscale consists of 17 items assessing difficulty in performing daily activities.
Scores range from 0 to 68, with higher scores indicating worse physical function.
|
Baseline (Day 0) and Week 4
|
|
2. Reduction of joint stiffness.
Tidsramme: Baseline and after 4 weeks of treatment
|
Baseline and after 4 weeks of treatment
|
|
|
Change in daily activities performance assessed by the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) Physical Function Subscale
Tidsramme: Baseline (Day 0) and Week 4
|
The WOMAC Physical Function Subscale consists of 17 items assessing difficulty in activities of daily living.
Scores range from 0 to 68, with higher scores indicating worse functional limitation.
|
Baseline (Day 0) and Week 4
|
Samarbejdspartnere og efterforskere
Det er her, du vil finde personer og organisationer, der er involveret i denne undersøgelse.
Sponsor
Efterforskere
- Studiestol: hane mohamed hamed, PHD, professor of orthopedic surgery depaetment of orthopedic surgery faculty of medicine kafrelsheikh university
- Studiestol: mahmoud mohamed ewida, PHD, professor of basic sciences for physical therapy department of basic sciences for physical therapy faculty oh physical therapy kafrelsheikh university
Datoer for undersøgelser
Disse datoer sporer fremskridtene for indsendelser af undersøgelsesrekord og resumeresultater til ClinicalTrials.gov. Studieregistreringer og rapporterede resultater gennemgås af National Library of Medicine (NLM) for at sikre, at de opfylder specifikke kvalitetskontrolstandarder, før de offentliggøres på den offentlige hjemmeside.
Studer store datoer
Studiestart (Anslået)
1. august 2026
Primær færdiggørelse (Anslået)
30. oktober 2026
Studieafslutning (Anslået)
1. april 2027
Datoer for studieregistrering
Først indsendt
12. juni 2026
Først indsendt, der opfyldte QC-kriterier
18. juni 2026
Først opslået (Faktiske)
24. juni 2026
Opdateringer af undersøgelsesjournaler
Sidste opdatering sendt (Faktiske)
24. juni 2026
Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier
18. juni 2026
Sidst verificeret
1. juni 2026
Mere information
Begreber relateret til denne undersøgelse
Yderligere relevante MeSH-vilkår
Andre undersøgelses-id-numre
- KFSIRB200-1047
Plan for individuelle deltagerdata (IPD)
Planlægger du at dele individuelle deltagerdata (IPD)?
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