Development of a brief scale of everyday functioning in persons with serious mental illness

Brent T Mausbach, Phillip D Harvey, Sherry R Goldman, Dilip V Jeste, Thomas L Patterson, Brent T Mausbach, Phillip D Harvey, Sherry R Goldman, Dilip V Jeste, Thomas L Patterson

Abstract

We developed and tested the validity of a brief scale to assess everyday functioning in persons with serious mental illness. A sample of 434 adults with schizophrenia or schizoaffective disorder were administered the University of California, San Diego, Performance-Based Skills Assessment (UPSA), which assesses functional skills in 5 areas of life functioning (eg, finances and planning). Through use of factor analysis, we developed the UPSA-Brief, which consists of 2 subscales (communication and financial) from the original UPSA. UPSA-Brief scores were correlated with cognitive functioning, symptoms of psychosis, age, and education. We further tested the sensitivity and specificity of the UPSA-Brief for predicting residential independence using receiver-operating characteristic (ROC) curves. Finally, sensitivity to change was assessed through comparison of 2 interventions for improving UPSA-Brief scores. UPSA-Brief scores were highly correlated with scores on the full version of the UPSA (r = .91), with overall cognitive functioning (r = .57), and with negative symptoms (r = -.32). The discriminant validity of the UPSA-Brief was adequate (ROC area under the curve [AUC] = 0.73; 95% confidence interval [CI]: 0.67-0.78), with greatest dichotomization for the UPSA-Brief at a cutoff score of 60. The UPSA-Brief was significantly better than the Dementia Rating Scale, Positive and Negative Syndromes Scale positive, and Positive and Negative Syndromes Scale negative at predicting residential independence (all P values < .05). Participants receiving a behavioral intervention also improved significantly compared with a support condition (P = .023). The UPSA-Brief has adequate psychometric properties, predicts residential independence, is sensitive to change, and requires only 10-15 minutes to administer. Therefore, the UPSA-Brief may be a useful performance-based functional outcome scale.

Figures

Fig. 1.
Fig. 1.
Receiver-operating characteristic analysis of comparison: prediction of residential independence. The UPSA-Brief and UPSA area under the curve estimates were 0.73 (95% confidence interval [CI]: 0.67–0.78) and 0.74 (95% CI: 0.68–0.79), respectively. UPSA = University of California, San Diego, Performance-Based Skills Assessment.

Source: PubMed

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