The COMET Sleep Research Platform

Deborah A Nichols, Steven DeSalvo, Richard A Miller, Darrell Jónsson, Kara S Griffin, Pamela R Hyde, James K Walsh, Clete A Kushida, Deborah A Nichols, Steven DeSalvo, Richard A Miller, Darrell Jónsson, Kara S Griffin, Pamela R Hyde, James K Walsh, Clete A Kushida

Abstract

Introduction: The Comparative Outcomes Management with Electronic Data Technology (COMET) platform is extensible and designed for facilitating multicenter electronic clinical research.

Background: Our research goals were the following: (1) to conduct a comparative effectiveness trial (CET) for two obstructive sleep apnea treatments-positive airway pressure versus oral appliance therapy; and (2) to establish a new electronic network infrastructure that would support this study and other clinical research studies.

Discussion: The COMET platform was created to satisfy the needs of CET with a focus on creating a platform that provides comprehensive toolsets, multisite collaboration, and end-to-end data management. The platform also provides medical researchers the ability to visualize and interpret data using business intelligence (BI) tools.

Conclusion: COMET is a research platform that is scalable and extensible, and which, in a future version, can accommodate big data sets and enable efficient and effective research across multiple studies and medical specialties. The COMET platform components were designed for an eventual move to a cloud computing infrastructure that enhances sustainability, overall cost effectiveness, and return on investment.

Keywords: COMET; business intelligence; cloud computing; comparative effectiveness research; obstructive sleep apnea; research platform.

Figures

Figure 7.
Figure 7.
CET Content Collection: COMET Data Pipeline Subsystem
Figure 1.
Figure 1.
COMET Platform Layers
Figure 2.
Figure 2.
CET Requirements for the Application Software Layer of the COMET Platform
Figure 3.
Figure 3.
Data Processing: COMET Data Pipeline Subsystem
Figure 4.
Figure 4.
Power Pivot Dashboard: COMET Collaboration and Presentation Subsystem
Figure 5.
Figure 5.
Power Pivot Report: COMET Collaboration and Presentation Subsystem
Figure 6.
Figure 6.
Future Cloud Computing Service Model
https://www.ncbi.nlm.nih.gov/pmc/articles/instance/4371444/bin/egems1059f8.jpg

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Source: PubMed

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