Prevalence of healthcare-associated infections, estimated incidence and composite antimicrobial resistance index in acute care hospitals and long-term care facilities: results from two European point prevalence surveys, 2016 to 2017

Carl Suetens, Katrien Latour, Tommi Kärki, Enrico Ricchizzi, Pete Kinross, Maria Luisa Moro, Béatrice Jans, Susan Hopkins, Sonja Hansen, Outi Lyytikäinen, Jacqui Reilly, Aleksander Deptula, Walter Zingg, Diamantis Plachouras, Dominique L Monnet, Healthcare-Associated Infections Prevalence Study Group, Carl Suetens, Katrien Latour, Tommi Kärki, Enrico Ricchizzi, Pete Kinross, Maria Luisa Moro, Béatrice Jans, Susan Hopkins, Sonja Hansen, Outi Lyytikäinen, Jacqui Reilly, Aleksander Deptula, Walter Zingg, Diamantis Plachouras, Dominique L Monnet, Healthcare-Associated Infections Prevalence Study Group

Abstract

Point prevalence surveys of healthcare-associated infections (HAI) and antimicrobial use in the European Union and European Economic Area (EU/EEA) from 2016 to 2017 included 310,755 patients from 1,209 acute care hospitals (ACH) in 28 countries and 117,138 residents from 2,221 long-term care facilities (LTCF) in 23 countries. After national validation, we estimated that 6.5% (cumulative 95% confidence interval (cCI): 5.4-7.8%) patients in ACH and 3.9% (95% cCI: 2.4-6.0%) residents in LTCF had at least one HAI (country-weighted prevalence). On any given day, 98,166 patients (95% cCI: 81,022-117,484) in ACH and 129,940 (95% cCI: 79,570-197,625) residents in LTCF had an HAI. HAI episodes per year were estimated at 8.9 million (95% cCI: 4.6-15.6 million), including 4.5 million (95% cCI: 2.6-7.6 million) in ACH and 4.4 million (95% cCI: 2.0-8.0 million) in LTCF; 3.8 million (95% cCI: 3.1-4.5 million) patients acquired an HAI each year in ACH. Antimicrobial resistance (AMR) to selected AMR markers was 31.6% in ACH and 28.0% in LTCF. Our study confirmed a high annual number of HAI in healthcare facilities in the EU/EEA and indicated that AMR in HAI in LTCF may have reached the same level as in ACH.

Keywords: AMR; HAI; LTCF; PPS; antimicrobial resistance; burden; healthcare-associated infections; hospitals; long-term care facilities; point prevalence survey.

Conflict of interest statement

Conflict of interest: None declared.

Figures

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Figure
Correlations of composite index of antimicrobial resistance, EU/EEA countries and Serbia, 2016–2017

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Source: PubMed

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