Acceptability of Iron- and Zinc-Biofortified Pearl Millet (Dhanashakti)-Based [corrected] Complementary Foods among Children in an Urban Slum of Mumbai, India

Samantha Lee Huey, Sudha Venkatramanan, Shobha A Udipi, Julia Leigh Finkelstein, Padmini Ghugre, Jere Douglas Haas, Varsha Thakker, Aparna Thorat, Ashwini Salvi, Anura V Kurpad, Saurabh Mehta, Samantha Lee Huey, Sudha Venkatramanan, Shobha A Udipi, Julia Leigh Finkelstein, Padmini Ghugre, Jere Douglas Haas, Varsha Thakker, Aparna Thorat, Ashwini Salvi, Anura V Kurpad, Saurabh Mehta

Abstract

Biofortification, a method for increasing micronutrient content of staple crops, is a promising strategy for combating major global health problems, such as iron and zinc deficiency. We examined the acceptability of recipes prepared using iron- and zinc-biofortified pearl millet (FeZnPM) (~80 ppm Fe, ~34 ppm Zn, varietal Dhanashakti), [corrected] compared to conventional pearl millet (CPM) (~20 ppm Fe, ~19 ppm Zn) in preparation for an efficacy trial. Our objective was to examine the acceptability of FeZnPM compared to CPM among young children and mothers living in the urban slums of Mumbai. Standardized traditional feeding program recipes (n = 18) were prepared with either FeZnPM or CPM flour. The weight (g) of each food product was measured before and after consumption by children (n = 125) and the average grams consumed over a 3-day period were recorded. Mothers (n = 60) rated recipes using a 9-point hedonic scale. Mean intakes and hedonic scores of each food product were compared using t-tests across the two types of pearl millet. There were no statistically significant differences in consumption by children (FeZnPM: 25.27 ± 13.0 g; CPM: 21.72 ± 6.90 g) across the food products (P = 0.28). Overall mean hedonic scores for all recipes were between 7 to 9 points. CPM products were rated higher overall (8.22 ± 0.28) compared to FeZnPM products (7.95 ± 0.35) (P = 0.01). FeZnPM and CPM were similarly consumed and had high hedonic scores, demonstrating high acceptability in this population. These results support using these varieties of pearl millet in a proposed trial [http://Clinicaltrials.gov ID: NCT02233764; Clinical Trials Registry of India (CTRI), reference number REF/2014/10/007731, CTRI number CTRI/2015/11/006376] testing the efficacy of FeZnPM for improving iron status and growth.

Keywords: ICTP-8203; acceptability; biofortification; children; iron; iron deficiency; pearl millet.

References

    1. Lopez A, Cacoub P, Macdougall IC, Peyrin-Biroulet L. Iron deficiency anaemia. Lancet (2016) 387:907–16.10.1016/S0140-6736(15)60865-0
    1. Vucic V, Berti C, Vollhardt C, Fekete K, Cetin I, Koletzko B, et al. Effect of iron intervention on growth during gestation, infancy, childhood, and adolescence: a systematic review with meta-analysis. Nutr Rev (2013) 71:386–401.10.1111/nure.12037
    1. Beard JL. Iron biology in immune function, muscle metabolism and neuronal functioning. J Nutr (2001) 131:568S–79S; discussion 580S.
    1. Lozoff B. Early iron deficiency has brain and behavior effects consistent with dopaminergic dysfunction. J Nutr (2011) 141:740S–6S.10.3945/jn.110.131169
    1. I.C.M.R. Nutrient Requirements and Recommended Dietary Allowances for Indians. Expert Group of the Indian Council of Medical Research , editor. Hyderabad: National Institute of Nutrition, Indian Council of Medical Research; (2009).
    1. Venkatramanan S, Haas JD, Finkelstein JL, Salvi A, Thorat A, Huey SL, et al. Dietary intake and nutritional status in infants from the urban slums of Mumbai, India. FASEB J (2016) 30(1 Suppl):891–14.
    1. Huey SL, Powis LE, Venkatramanan S, Udipi SA, Finkelstein JL, Ghugre P, et al. Pre-intervention characterization of nutritional status to estimate burden and potential to benefit among mothers and their children living in urban slums of Mumbai, India. International Congress of Nutrition (Forthcoming). Buenos Aires: International Union of Nutritional Sciences; (2017).
    1. Black RE. Zinc deficiency, infectious disease and mortality in the developing world. J Nutr (2003) 133:1485S–9S.
    1. Black RE, Victora CG, Walker SP, Bhutta ZA, Christian P, De Onis M, et al. Maternal and child undernutrition and overweight in low-income and middle-income countries. Lancet (2013) 382:427–51.10.1016/S0140-6736(13)60937-X
    1. Finkelstein JL, Mehta S, Udipi SA, Ghugre PS, Luna SV, Wenger MJ, et al. A randomized trial of iron-biofortified pearl millet in school children in India. J Nutr (2015) 145:1576–81.10.3945/jn.114.208009
    1. Bouis HE. Plant breeding: a new tool for fighting micronutrient malnutrition. J Nutr (2002) 132:491S–4S.
    1. Nestel P, Bouis HE, Meenakshi JV, Pfeiffer W. Biofortification of staple food crops. J Nutr (2006) 136:1064–7.
    1. Basavaraj G, Rao PP, Bhagavatula S, Ahmed W. Availability and utilization of pearl millet in India. J SAT Agric Res (2010) 8:1–13.
    1. Finkelstein JL, Haas JD, Mehta S. Iron-biofortified staple food crops for improving iron status: a review of the current evidence. Curr Opin Biotechnol (2017) 44:138–45.10.1016/j.copbio.2017.01.003
    1. I.C.R.I.S.A.T. Pearl millet open-pollinated variety ICTP 8203. Plant Material Description No. 18. International Crops Research Institute for the Semi-Arid Tropics; (1989). p. 1–4.
    1. Kodkany BS, Bellad RM, Mahantshetti NS, Westcott JE, Krebs NF, Kemp JF, et al. Biofortification of pearl millet with iron and zinc in a randomized controlled trial increases absorption of these minerals above physiologic requirements in young children. J Nutr (2013) 143:1489–93.10.3945/jn.113.176677
    1. Prinja S, Verma R, Lal S. Role of ICDS program in delivery of nutritional services and functional integration between anganwadi and health worker in north India. J Nutr Wellness (2008) 5:8–15.
    1. Tomlins K, Manful J, Gayin J, Kudjawu B, Tamakloe I. Study of sensory evaluation, consumer acceptability, affordability and market price of rice. J Sci Food Agric (2007) 87:1564–75.10.1002/jsfa.2889
    1. Shamim AA, Hanif AA, Merrill RD, Campbell RK, Kumkum MA, Shaikh S, et al. Preferred delivery method and acceptability of Wheat-Soy Blend (WSB++) as a daily complementary food supplement in northwest Bangladesh. Ecol Food Nutr (2015) 54:74–92.10.1080/03670244.2014.930030
    1. Banerji A, Birol E, Karandikar B, Rampal J. Information, branding, certification, and consumer willingness to pay for high-iron pearl millet: evidence from experimental auctions in Maharashtra, India. Food Policy (2016) 62:133–41.10.1016/j.foodpol.2016.06.003
    1. WHO. WHO child growth standards and the identification of severe acute malnutrition in infants and children. A Joint Statement by the WHO and UNICEF. Geneva: WHO, UNICEF; (2009).
    1. Garcia-Casal MN, Pena-Rosas JP, Giyose B, Consultation Working Group Staple crops biofortified with increased vitamins and minerals: considerations for a public health strategy. Ann N Y Acad Sci (2016) 1:1–11.10.1111/nyas.13293
    1. Kodkany B, Bellad R, Mahantshetti N, Westcott J, Krebs N, Kemp J, et al. Biofortification of pearl millet with iron and zinc in a randomized controlled trial increases absorbtion of these minerals above physiologic requirements in young children – erratum. J Nutr (2013) 143:2055.10.3945/jn.113.176677
    1. Talsma EF, Melse-Boonstra A, De Kok BP, Mbera GN, Mwangi AM, Brouwer ID. Biofortified cassava with pro-vitamin A is sensory and culturally acceptable for consumption by primary school children in Kenya. PLoS One (2013) 8:e73433.10.1371/journal.pone.0073433
    1. Pachon H, Dominguez MR, Creed-Kanashiro H, Stoltzfus RJ. Acceptability and safety of novel infant porridges containing lyophilized meat powder and iron-fortified wheat flour. Food Nutr Bull (2007) 28:35–46.10.1177/156482650702800104
    1. Adu-Afarwuah S, Lartey A, Zeilani M, Dewey KG. Acceptability of lipid-based nutrient supplements (LNS) among Ghanaian infants and pregnant or lactating women. Matern Child Nutr (2011) 7:344–56.10.1111/j.1740-8709.2010.00286.x
    1. Ahmed T, Choudhury N, Hossain MI, Tangsuphoom N, Islam MM, De Pee S, et al. Development and acceptability testing of ready-to-use supplementary food made from locally available food ingredients in Bangladesh. BMC Pediatr (2014) 14:164.10.1186/1471-2431-14-164

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