Respiratory physiology of pregnancy: Physiology masterclass

Antonella LoMauro, Andrea Aliverti, Antonella LoMauro, Andrea Aliverti

Abstract

Physiology masterclass: respiratory physiology of pregnancy http://ow.ly/UvYXt.

Conflict of interest statement

Conflict of interest None declared.

Figures

Figure 1
Figure 1
Flow diagram summarising the most important effects of biochemical (left) and mechanical (right) pregnancy-induced factors on pulmonary function, ventilatory pattern and gas exchange. PO2: oxygen tension; PCO2: carbon dioxide tension; FRC: functional residual capacity; ERV: expiratory reserve volume; TLC: total lung capacity; IC: inspiratory capacity; VC: vital capacity; ↑: increased; ↓: decreased; ≈: no change.

References

    1. Weinberger SE, Weiss ST, Cohen WR, et al. . Pregnancy and the lung. Am Rev Respir Dis 1980; 121: 559–581.
    1. Contreras G, Gutiérrez M, Beroíza T, et al. . Ventilatory drive and respiratory muscle function in pregnancy. Am Rev Respir Dis 1991; 144: 837–841.
    1. Gilroy RJ, Mangura BT, Lavietes MH. Rib cage and abdominal volume displacements during breathing in pregnancy. Am Rev Respir Dis 1988; 137: 668–672.
    1. Jensen D, Webb KA, Davies GA, et al. . Mechanical ventilatory constraints during incremental cycle exercise in human pregnancy: implications for respiratory sensation. J Physiol 2008; 586: 4735–4750.
    1. Jensen D, Duffin J, Lam YM, et al. . Physiological mechanisms of hyperventilation during human pregnancy. Respir Physiol Neurobiol 2008; 161: 76–86.
    1. Lyons HA, Antonio R. The sensitivity of the respiratory center in pregnancy and after administration of progesterone. Trans Assoc Am Physicians 1959; 72: 173–180.
    1. McAuliffe F, Kametas N, Costello J, et al. . Respiratory function in singleton and twin pregnancy. BJOG 2002; 109: 765–769.
    1. Kolarzyk E, Szot WM, Lyszczarz J. Lung function and breathing regulation parameters during pregnancy. Arch Gynecol Obstet 2005; 272: 53–58.
    1. Grindheim G, Toska K, Estensen ME, et al. . Changes in pulmonary function during pregnancy: a longitudinal cohort study. BJOG 2012; 119: 94–101.
    1. Lapinsky SE, Tram C, Mehta S, et al. . Restrictive lung disease in pregnancy. Chest 2014; 145: 394–398.
    1. Lemos A, de Souza AI, Figueiroa JN, et al. . Respiratory muscle strength in pregnancy. Respir Med 2010; 104: 1638–1644.
    1. McGinty AP. The comparative effects of pregnancy and phrenic nerve interruption on the diaphragm and their relation to pulmonary tuberculosis. Am J Obstet Gynecol 1938; 35: 237–248.
    1. Gilleard WL, Brown JM. Structure and function of the abdominal muscles in primigravid subjects during pregnancy and the immediate postbirth period. Phys Ther 1996; 76: 750–762.
    1. Weis CA, Triano JJ, Barrett J, et al. . Ultrasound assessment of abdominal muscle thickness in postpartum vs nulliparous women. J Manipulative Physiol Ther 2015; 38: 352–357.
    1. Campbell LA, Klocke RA. Implications for the pregnant patient. Am J Respir Crit Care Med 2001; 163: 1051–1054.
    1. da Silva EG, de Godoy I, de Oliveira Antunes LC, et al. . Respiratory parameters and exercise functional capacity in preeclampsia. Hypertens Pregnancy 2010; 29: 301–309.
    1. Vos R, Ruttens D, Verleden SE, et al. . Pregnancy after heart and lung transplantation. Best Pract Res Clin Obstet Gynaecol 2014; 28: 1146–1162.
    1. Norwood F, Rudnik-Schöneborn S. 179th ENMC international workshop: pregnancy in women with neuromuscular disorders 5–7 November 2010, Naarden, The Netherlands. Neuromuscul Disord 2012; 22: 183–190.
    1. Duarte AG. ARDS in pregnancy. Clin Obstet Gynecol 2014; 57: 862–870.
    1. Lapinsky SE, Kruczynski K, Slutsky AS. Critical care in the pregnant patient. Am J Respir Crit Care Med 1995; 152: 427–455.

Source: PubMed

Sponsorer og samarbejdspartnere

Medicinske tilstande

Narkotikainterventioner

3
Abonner