Back pain in seniors: the Back pain Outcomes using Longitudinal Data (BOLD) cohort baseline data

Jeffrey G Jarvik, Bryan A Comstock, Patrick J Heagerty, Judith A Turner, Sean D Sullivan, Xu Shi, David R Nerenz, Srdjan S Nedeljkovic, Larry Kessler, Kathryn James, Janna L Friedly, Brian W Bresnahan, Zoya Bauer, Andrew L Avins, Richard A Deyo, Jeffrey G Jarvik, Bryan A Comstock, Patrick J Heagerty, Judith A Turner, Sean D Sullivan, Xu Shi, David R Nerenz, Srdjan S Nedeljkovic, Larry Kessler, Kathryn James, Janna L Friedly, Brian W Bresnahan, Zoya Bauer, Andrew L Avins, Richard A Deyo

Abstract

Background: Back pain represents a substantial burden globally, ranking first in a recent assessment among causes of years lived with disability. Though back pain is widely studied among working age adults, there are gaps with respect to basic descriptive epidemiology among seniors, especially in the United States. Our goal was to describe how pain, function and health-related quality of life vary by demographic and geographic factors among seniors presenting to primary care providers with new episodes of care for back pain.

Methods: We examined baseline data from the Back pain Outcomes using Longitudinal Data (BOLD) registry, the largest inception cohort to date of seniors presenting to a primary care provider for back pain. The sample included 5,239 patients ≥ 65 years old with a new primary care visit for back pain at three integrated health systems (Northern California Kaiser-Permanente, Henry Ford Health System [Detroit], and Harvard Vanguard Medical Associates [Boston]). We examined differences in patient characteristics across healthcare sites and associations of patient sociodemographic and clinical characteristics with baseline patient-reported measures of pain, function, and health-related quality of life.

Results: Patients differed across sites in demographic and other characteristics. The Detroit site had more African-American patients (50%) compared with the other sites (7-8%). The Boston site had more college graduates (68%) compared with Detroit (20%). Female sex, lower educational status, African-American race, and older age were associated with worse functional disability as measured by the Roland-Morris Disability Questionnaire. Except for age, these factors were also associated with worse pain.

Conclusions: Baseline pain and functional impairment varied substantially with a number of factors in the BOLD cohort. Healthcare site was an important factor. After controlling for healthcare site, lower education, female sex, African-American race, and older age were associated with worse physical disability and all of these factors except age were associated with worse pain.

Trial registration: Clinical Trials.gov NCT01776242; Registration date: June 13, 2012.

Figures

Figure 1
Figure 1
Consort diagram depicting patient flow from initial screening through enrollment.
Figure 2
Figure 2
Roland-Morris Disability Questionnaire (RMDQ) and average back pain intensity in past week by age, race, sex and education stratified by site. a, c, e, and g display the baseline measure of back-related physical disability (the Roland-Morris disability questionnaire) and b, d, f, h display the baseline measure of pain (a numerical rating scale of average back pain in past week), stratified by site and compared with key demographic variables. a and b depict baseline measures by age; c and d depict baseline measures by race; e and f depict baseline measures by sex; and g and h depict baseline measures by education. Each outcome by demographic boxplot displays the within-group mean (horizontal in the center of the box) +/- the within-group standard deviation (upper and lower edges of the box). The vertical lines display the within-group range of scores.
Figure 3
Figure 3
RMDQ and back pain intensity by ICD-9-CM code stratified by site. a displays the baseline measure of back-related physical disability (the Roland-Morris disability questionnaire) and b displays the baseline measure of pain (a numerical rating scale of average back pain in past week), stratified by site and compared with primary diagnosis code for the index visit using ICD-9-CM. Each outcome by demographic boxplot displays the within-group mean (horizontal in the center of the box) +/- the within-group standard deviation (upper and lower edges of the box). The vertical lines display the within-group range of scores.

References

    1. Vos T, Flaxman AD, Naghavi M, Lozano R, Michaud C, Ezzati M, Shibuya K, Salomon J, Abdalla S, Aboyans V, Abraham J, Ackerman I, Aggarwal R, Ahn S, Ali M, AlMazroa M, Alvarado M, Anderson H, Anderson L, Andrews K, Atkinson C, Baddour L, Bahalim A, Barker-Collo S, Barrero L, Bartels D, Basáñez M-G, Baxter A, Bell M, Benjamin E. et al.Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the global burden of disease study 2010. Lancet. 2012;380:2163–2196.
    1. Collaborators USBoD. The state of US health, 1990–2010: burden of diseases, injuries, and risk factors. JAMA. 2013;310:591–608.
    1. Bressler HB, Keyes WJ, Rochon PA, Badley E. The prevalence of low back pain in the elderly: a systematic review of the literature. Spine (Phila Pa 1976) 1999;24:1813–1819.
    1. Scheele J, Luijsterburg PA, Bierma-Zeinstra SM, Koes BW. Course of back complaints in older adults: a systematic literature review. Eur J Phys Rehabil Med. 2012;48:379–386.
    1. Macfarlane GJ, Beasley M, Jones EA, Prescott GJ, Docking R, Keeley P, McBeth J, Jones G. The prevalence and management of low back pain across adulthood: results from a population-based cross-sectional study (the MUSICIAN study) Pain. 2012;153:27–32.
    1. Scheele J, Enthoven WT, Bierma-Zeinstra SM, Peul WC, van Tulder MW, Bohnen AM, Berger MY, Koes BW, Luijsterburg PA. Course and prognosis of older back pain patients in general practice: A prospective cohort study. Pain. 2013;154(6):951–957.
    1. Scheele J, Enthoven WT, Bierma-Zeinstra SM, Peul WC, van Tulder MW, Bohnen AM, Berger MY, Koes BW, Luijsterburg PA. Characteristics of older patients with back pain in general practice: BACE cohort study. Eur J Pain. 2014;18(2):279–287.
    1. Jarvik JG, Comstock BA, Bresnahan BW, Nedeljkovic SS, Nerenz DR, Bauer Z, Avins AL, James K, Turner JA, Heagerty P, Kessler L, Friedly JL, Sullivan SD, Deyo RA. Study protocol: the back pain outcomes using longitudinal data (BOLD) registry. BMC Musculoskelet Disord. 2012;13:64.
    1. Statistics NCfH. International classification of diseases, ninth revision (ICD-9)], 2009. Available at: .
    1. Roland M, Morris R. A study of the natural history of back pain: part 1: development of a reliable and sensitive measure of disability in low back pain. Spine. 1983;8:141–144.
    1. Cleeland CS, Nakamura Y, Mendoza TR, Edwards KR, Douglas J, Serlin RC. Dimensions of the impact of cancer pain in a four country sample: new information from multidimensional scaling. Pain. 1996;67:267–273.
    1. Cleeland CS, Ryan KM. Pain assessment: global use of the brief pain inventory. Ann Acad Med Singapore. 1994;23:129–138.
    1. Kroenke K, Spitzer RL, Williams JB, Lowe B. An ultra-brief screening scale for anxiety and depression: the PHQ-4. Psychosomatics. 2009;50:613–621.
    1. Lowe B, Wahl I, Rose M, Spitzer RL, Glaesmer H, Wingenfeld K, Schneider A, Brahler E. A 4-item measure of depression and anxiety: validation and standardization of the patient health questionnaire-4 (PHQ-4) in the general population. J Affect Disord. 2010;122:86–95.
    1. Brooks R. EuroQOL: the current state of play. Health Policy. 1996;37:53–72.
    1. Stevens JA, Mack KA, Paulozzi LJ, Ballesteros MF. Self-reported falls and fall-related injuries among persons aged > or =65 years--United States, 2006. CDC MMWR Morb Mortal Wkly Rep. 2008;57:225–229.
    1. Iles RA, Davidson M, Taylor NF, O’Halloran P. Systematic review of the ability of recovery expectations to predict outcomes in non-chronic non-specific low back pain. J Occup Rehabil. 2009;19:25–40.
    1. Kongsted A, Vach W, Axo M, Bech RN, Hestbaek L. Expectation of recovery from low back pain: a longitudinal cohort study investigating patient characteristics related to expectations and the association between expectations and 3-month outcome. Spine (Phila Pa 1976) 2014;39:81–90.
    1. Fenge LA, Hean S, Worswick L, Wilkinson C, Fearnley S, Ersser S. The impact of the economic recession on well-being and quality of life of older people. Health Soc Care Community. 2012;20:617–624.
    1. Dionne CE, Von Korff M, Koepsell TD, Deyo RA, Barlow WE, Checkoway H. Formal education and back pain: a review. J Epidemiol Community Health. 2001;55:455–468.
    1. Lacey RJ, Belcher J, Croft PR. Does life course socio-economic position influence chronic disabling pain in older adults? A general population study. Eur J Pub Health. 2013;23:534–540.
    1. Bartley EJ, Fillingim RB. Sex differences in pain: a brief review of clinical and experimental findings. Br J Anaesth. 2013;111:52–58.
    1. Fillingim RB, King CD, Ribeiro-Dasilva MC, Rahim-Williams B, Riley JL. Sex, gender, and pain: a review of recent clinical and experimental findings. J Pain. 2009;10:447–485.
    1. Hurley RW, Adams MC. Sex, gender, and pain: an overview of a complex field. Anesth Analg. 2008;107:309–317.
    1. Creamer P, Lethbridge-Cejku M, Hochberg MC. Determinants of pain severity in knee osteoarthritis: effect of demographic and psychosocial variables using 3 pain measures. J Rheumatol. 1999;26:1785–1792.
    1. Thomas E, Peat G, Harris L, Wilkie R, Croft PR. The prevalence of pain and pain interference in a general population of older adults: cross-sectional findings from the North Staffordshire osteoarthritis project (NorStOP) Pain. 2004;110:361–368.
    1. Parsons S, Breen A, Foster NE, Letley L, Pincus T, Vogel S, Underwood M. Prevalence and comparative troublesomeness by age of musculoskeletal pain in different body locations. Fam Pract. 2007;24:308–316.
    1. Patel KV, Guralnik JM, Dansie EJ, Turk DC. Prevalence and impact of pain among older adults in the United States: Findings from the 2011 National Health and Aging Trends Study. Pain. 2013;154(12):2649–2657.
    1. Li CY, Sung FC. A review of the healthy worker effect in occupational epidemiology. Occup Med. 1999;49:225–229.
    1. Dave D, Rashad I, Spasojevic J. NBER working paper series. Cambridge, MA: National Bureau of Economic Research; 2006. The effects of retirement on physical and mental health outcomes.
    1. Christ SL, Lee DJ, Fleming LE, LeBlanc WG, Arheart KL, Chung-Bridges K, Caban AJ, McCollister KE. Employment and occupation effects on depressive symptoms in older Americans: does working past age 65 protect against depression? J Gerontol B Psychol Sci Soc Sci. 2007;62:S399–S403.
    1. Olsen TL, Anderson RL, Dearwater SR, Kriska AM, Cauley JA, Aaron DJ, LaPorte RE. The epidemiology of low back pain in an adolescent population. Am J Public Health. 1992;82:606–608.
    1. Baker TA, Green CR. Intrarace differences among black and white americans presenting for chronic pain management: the influence of age, physical health, and psychosocial factors. Pain Med. 2005;6:29–38.
    1. Waterman BR, Belmont PJ Jr, Schoenfeld AJ. Low back pain in the United States: incidence and risk factors for presentation in the emergency setting. Spine J. 2012;12:63–70.
    1. Carey TS, Freburger JK, Holmes GM, Jackman A, Knauer S, Wallace A, Darter J. Race, care seeking, and utilization for chronic back and neck pain: population perspectives. J Pain. 2010;11:343–350.
    1. Grotle M, Brox JI, Veierod MB, Glomsrod B, Lonn JH, Vollestad NK. Clinical course and prognostic factors in acute low back pain: patients consulting primary care for the first time. Spine (Phila Pa 1976) 2005;30:976–982.
    1. Selim AJ, Fincke G, Ren XS, Deyi RA, Lee A, Skinner K, Kazis L. Patient characteristics and patterns of use for lumbar spine radiographs: results from the veterans health study. Spine. 2000;25:2440–2444.
    1. Tubach F, Beaute J, Leclerc A. Natural history and prognostic indicators of sciatica. J Clin Epidemiol. 2004;57:174–179.
    1. Behrend C, Prasarn M, Coyne E, Horodyski M, Wright J, Rechtine GR. Smoking cessation related to improved patient-reported pain scores following spinal care. J Bone Joint Surg Am. 2012;94:2161–2166.
    1. Scheele J, Luijsterburg PA, Ferreira ML, Maher CG, Pereira L, Peul WC, van Tulder MW, Bohnen AM, Berger MY, Luijsterburg PA, Koes BW. Back complaints in the elders (BACE); design of cohort studies in primary care: an international consortium. BMC Musculoskelet Disord. 2011;12:193.

Source: PubMed

3
Abonner