Use of national standards to monitor HIV care and treatment in a high prevalence city-Washington, DC

Amanda D Castel, Arpi Terzian, Rachel Hart, Nabil Rayeed, Mariah M Kalmin, Heather Young, Alan E Greenberg, DC Cohort Executive Committee, Amanda D Castel, Arpi Terzian, Rachel Hart, Nabil Rayeed, Mariah M Kalmin, Heather Young, Alan E Greenberg, DC Cohort Executive Committee

Abstract

We sought to benchmark the quality of HIV care being received by persons living with HIV in care in Washington, DC and identify individual-level and structural-level differences. Data from the DC Cohort, an observational HIV cohort of persons receiving outpatient care in DC, were used to estimate the Institute of Medicine (IOM) and Department of Health and Human Services (HHS) quality of care measures. Differences in care by demographics and clinic type were assessed using χ2 tests and multivariable regression models. Among 8,047 participants, by HHS standards, 69% of participants were retained in care (RIC), 95% were prescribed antiretroviral therapy (ART), and 84% were virally suppressed (VS). By IOM standards, 84% were in continuous care; and 78% and 80% underwent regular CD4 and VL monitoring, respectively. Screening for syphilis, chlamydia, and gonorrhea was 51%, 31%, and 26%, respectively. Older participants were 1.5 times more likely to be RIC compared to younger participants (OR: 1.5; 95% CI: 1.3, 1.8). Participants enrolled in community-based clinics were more likely to be RIC (OR: 1.7; 95% CI: 1.4, 2.0) versus those enrolled at hospital-based clinics. Older participants were more likely to achieve VS than younger participants (OR: 1.8; 95% CI: 1.5, 2.2) while Black participants were less likely compared to white participants (OR: 0.4; 95% CI: 0.3, 0.5). Despite high measures of quality of care, disparities remain. Continued monitoring of the quality of HIV care and treatment can inform the development of public health programs and interventions to optimize care delivery.

Conflict of interest statement

Competing Interests: Despite the role of Cerner Corporation in the design and conduct of the DC Cohort study and analysis, this commercial affiliation does not alter our adherence to PLOS one policies on sharing data and materials.

Figures

Fig 1. Proportion of DC cohort participants…
Fig 1. Proportion of DC cohort participants meeting criteria for selected HHS and IOM indicators for quality of care, DC cohort, 2011–2016.
This figure represents individuals who were enrolled in the DC Cohort as of September 30, 2016 and met the criteria for selected Department of Health and Human Services and Institute of Medicine HIV quality of care indicators. While high proportions of participants met the HIV-related indicators (69%-95%), screening for sexually transmitted infections was relatively low (26%-51%).

References

    1. Office of National AIDS Policy. National HIV/AIDS Strategy for the United States 2015 [Available from: .
    1. Valdiserri R, Forsyth A, Yakovchenko V, Koh H. Measuring What Matters: Development of Standard Indicators across the US Department of Health and Human Services Public Health Reports. Public Health Reports. 2013;128(5): 354–9. doi:
    1. Health Resources Services Administration. The HIV/AIDS Program: HAB performance measures group 1 [Available from: .
    1. Ford M, Spicer C. Monitoring HIV care in the United States. National Academies Press. 2012;1:150–2.
    1. Althoff K, Reberio P, Brooks J, Buchacz K, Gebo K, Martin J et al. Disparities in the quality of HIV care when using US Department of Health and Human Services indicators. Clinical infectious diseases. 2014;58(8): 1185–9. DOI:10.1093/cid/ciu044 doi:
    1. Burchell A, Gardner S, Light L, Ellis B, Antoniou T, Bacon J et al. Implementation and Operational Research. JAIDS Journal of Acquired Immune Deficiency Syndromes. 2015;70(1):e10–e9. DOI: 10.1097/QAI.0000000000000690 doi:
    1. Hall H, Gray K, Tang T, Li J, Shouse L, Mermin J. Retention in Care of Adults and Adolescents Living in 13 US Areas. JAIDS Journal of Acquired Immune Deficiency Syndromes. 1824;60(1):77–82. DOI: 10.1097/QAI.0b013e318249fe90
    1. Mahle Gray K, Tang T, Shouse L, Li J, Mermin J, Hall H. Using the HIV Surveillance System to Monitor the National HIV/AIDS Strategy. American Journal of Public Health. 2012;103(1):141–7. DOI: 10.2105/AJPH.2012.300859 doi:
    1. District of Columbia Department of Health HIV/AIDS Hepatitis, STD, and TB Administration. Annual Epidemiology and Surveillance Report, 2015 [Available from: .
    1. Greenberg A, Hays H, Castel A, Subramanian T, Happ L, Jaurretche M et al. Development of a large urban longitudinal HIV clinical cohort using a web-based platform to merge electronically and manually abstracted data from disparate medical record systems: technical challenges and innovative solutions. Journal of the American Medical Informatics Association. 2015;23(3): 635–43. DOI: 10.1093/jamia/ocv176 doi:
    1. Patient Protection Act. USC § 18001 2010 [Available from: .
    1. Castel A, Opoku J, Powers Happ L et al. Increasing the Completeness of Health Surveillance and Clinical Research Databases: Linkage of District of Columbia Surveillance Data with DC Cohort Study Data-Washington, DC. National HIV Prevention Conference 2015.
    1. Castel AD, on behalf of the DC Cohort Executive Commitee. Implementation of a City-Wide Cohort of HIV-Infected Persons in Care in Washington DC. The XIX International AIDS Conference2012.
    1. Rebeiro P, Althoff K, Lau B, Gill J, Abraham A, Horberg M et al. Laboratory Measures as Proxies for Primary Care Encounters: Implications for Quantifying Clinical Retention Among HIV-infected Adults in North America. American Journal of Epidemiology. 2015;182(11):952–60. DOI: 10.1093/aje/kwv181. Epub 2015 Nov 17. doi:
    1. Sabharwal C, Braunstein S, Robbins R, Shepard C. Optimizing the Use of Surveillance Data for Monitoring the Care Status of Persons Recently Diagnosed with HIV in NYC. JAIDS Journal of Acquired Immune Deficiency Syndromes. 2014;65(5): 571–8. DOI: 10.1097/QAI.0000000000000077. doi:
    1. Cohen S, Hu X, Sweeney P, Johnson A, Hall H. HIV Viral Suppression Among Persons With Varying Levels of Engagement in HIV Medical Care, 19 US Jurisdictions. JAIDS Journal of Acquired Immune Deficiency Syndromes. 2014;67(5):519–27. DOI: 10.1097/QAI.0000000000000349. doi:
    1. Dean B, Hart R, Buchacz K, Bozzette S, Wood K, Brooks J. HIV Laboratory Monitoring Reliably Identifies Persons Engaged in Care. JAIDS Journal of Acquired Immune Deficiency Syndromes 2015;68(2):133–9. DOI: 10.1097/QAI.0000000000000406. doi:
    1. Rebeiro P, Gange S, Horberg M, Abraham A, Napravnik S, Samji H et al. Geographic Variations in Retention in Care among HIV-Infected Adults in the United States. PLOS ONE 2016;11(1). DOI: 10.1371/journal.pone.0146119.
    1. Yehia B, Rebeiro P, Althoff K, Agwu A, Horberg M, Samji H et al. Impact of Age on Retention in Care and Viral Suppression. JAIDS Journal of Acquired Immune Deficiency Syndromes 2015;68(4):413–9. DOI: 10.1097/QAI.0000000000000489 doi:
    1. Marks G, Gardner L, Craw J, Crepaz N. Entry and retention in medical care among HIV-diagnosed persons: a meta-analysis. AIDS 2010;24(17):2665–78. DOI: 10.1097/QAD.0b013e32833f4b1b. doi:
    1. Yehia B, Stephens-Shields A, Fleishman J, Berry S, Agwu A, Metlay J et al. The HIV Care Continuum: changes over time in retention in care and viral suppression. PLOS ONE. 2015;10(6). e0129376 DOI:10.1371/journal.one.0129376. doi:
    1. District of Columbia Department of Health HIV/AIDS H, STD, and TB Administration. HIV Care and Ryan White Dynamics 2016. Available from: .
    1. Korthuis P, McGinnis K, Kraemer K, Gordon A, Skanderson M, Justice A et al. Quality of HIV Care and Mortality Rates in HIV-Infected Patients. Clinical Infectious Diseases 2015;62(2):233–9. doi:
    1. Hall H, Frazier E, Rhodes P, Holtgrave D, Furlow-Parmley C, Tang T et al. Differences in Human Immunodeficiency Virus Care and Treatment Among Subpopulations in the United States. JAMA Internal Medicine. 2013;173(14). DOI: 10.1001/jamainternmed.2013.6841.
    1. Xia Q, Braunstein S, Wiewel E, Eavey J, Shepard C, Torian L. Persons Living with HIV in the United States. JAIDS Journal of Acquired Immune Deficiency Syndromes. 2016. DOI: 10.1097/QAI.0000000000001008
    1. Greer G, Tamhane A, Malhotra R, Burkholder G, Mugavero M, Raper J et al. Achieving Core Indicators for HIV Care Among New Patients at an Urban HIV Clinic. AIDS Patient Care and STDs. 2015;29(9):474–80. DOI: 10.1089/apc.2015.0028. doi:
    1. Berry S, Ghanem K, Mathews W, Korthuis P, Yehia B, Agwu A et al. Brief Report. JAIDS Journal of Acquired Immune Deficiency Syndromes. 2015;70(3):275–9. DOI: 10.1097/QAI.0000000000000711. doi:
    1. Mattson C, Bradley H, Beer L, Johnson C, Pearson W, Shouse R. Increased STD testing among sexually active persons receiving medical care for HIV infection in the United States. Clinical Infectious Diseases. 2016:2009–13. DOI: 10.1093/cid/ciw834
    1. Lachowsky N, Stephenson K, Cui Z. The Momentum Healthy Study Incident Syphilis, Gonorrhea, and Chlamydia infection Among a Cohort of MSM. Conference on Retroviruses and Opportunistic Infections, 2016.
    1. Dorsey K, Castel A, Allston A. The Importance of Linkage and Engagement of Care in Post HIV STI Acquisition. Conference on Retroviruses and Opportunistic Infections. 2016.
    1. Skinner J, Distefano J, Warrington J, Bailey S, Winscott M, Taylor M. Trends in Reported Syphilis and Gonorrhea among HIV-Infected People in Arizona: Implications for Prevention and Control. Public Health Reports. 2014;129(1_suppl1):85–94. DOI: 10.1177/00333549141291S113.
    1. Castel AD, Kalmin M, Hart R et al. Disparities in achieving and sustaining viral suppression among a large cohort of HIV-infected persons in care—Washington, DC. AIDS Care. 2016;28:1355–64. doi:
    1. Thakarar K, Morgan J.R, Gaeta J.M, Hohl C, & Drainoni M.L. Homelessness, HIV, and Incomplete Viral Suppression. Journal of Health Care for the Poor and Underserved. 2016. 27(1):145–56. doi:
    1. Aidala AA, Wilson MG, Shubert V, Gogolishvili D, Globerman J, Rueda S, et al. Housing Status, Medical Care, and Health Outcomes Among People Living With HIV/AIDS: A Systematic Review. American Journal of Public Health. 2016;7(4).
    1. Riley ED NT, Moore K., Cohen J, Bangsberg DR, Havlir D. Social, structural and behavioral determinants of overall health status in a cohort of homeless and unstably housed HIV- infected men. PLOS One. 2012;7(4).
    1. Milloy MJ KT, Bangsberg DR, Buxton J, Parashar S, Guillemi S, Montaner J, Wood E. Homelessness as a structural barrier to effective antiretroviral therapy among HIV-seropositive illicit drug users in a Canadian setting. AIDS Patient Care STDS.2012;26(1):60–7. doi:
    1. Zanoni B, Mayer K. The Adolescent and Young Adult HIV Cascade Care in the United States: Exaggerated Health Disparities. AIDS Patient Care and STDs. 2013;28(3):128–35. DOI:10.1089/apc.2013.0345.
    1. Schranz A, Brady K, Momplaisir F, Metlay J, Stephens A, Yehia B. Comparison of HIV Outcomes for Patients Linked at Hospitals Versus Community-Based Clinics. AIDS patient care and STDs. 2014;29(3):117–25. DOI: 10.1089/apc.2014.0199.
    1. Chu C, Umanski G, Blank A, Grossberg R, Selwyn P. HIV-infected patients and treatment outcomes: an equivalence study of community-located, primary care-based HIV treatment vs. hospital-based specialty care in the Bronx, New York. AIDS Care. 2010;22(12):1522–9. DOI: 10.1080/09540121.2010.484456. doi:
    1. Horberg M. Continuity of care: Tracking patients across health plans and clinical settings. International Association of Physicians in AIDS Care (IAPAC) 2016.
    1. Herwehe J, Wilbright W, Abrams A, Bergson S, Foxhood J, Kaiser M. Implementation of an innovative, integrated electronic medical record (EMR) and public health information exchange for HIV/AIDS. Journal of the American Medical Informatics Association. 2012;19(3):448–52. doi:

Source: PubMed

3
Abonner