Descriptive retrospective study analyzing relevant factors related to dental implant failure

L Castellanos-Cosano, A Rodriguez-Perez, S Spinato, M Wainwright, G Machuca-Portillo, M-A Serrera-Figallo, D Torres-Lagares, L Castellanos-Cosano, A Rodriguez-Perez, S Spinato, M Wainwright, G Machuca-Portillo, M-A Serrera-Figallo, D Torres-Lagares

Abstract

Background: The objective of this retrospective descriptive study was to analyze the characteristics of incident reports provided by dentists while using a specific brand of dental implants.

Material and methods: The study was carried out in collaboration with Oxtein Iberia S.L., with the company providing access to the incident database in order to evaluate the characteristics of incidents from January 2014 to December 2017 (a total of 917 over four years). The data sheet recorded different variables during each of the stages of implant treatment, from initial implant placement to subsequent prosthetic rehabilitation. These variables included age, sex, systemic pathologies, smoking habits, bone quality, implant type, prosthesis type, and type of load applied, among others. SPSS Statistics was used to perform statistical analysis of the qualitative variables (univariate logistic regressions, χ2 test, Haberman's adjusted standardized residuals).

Results: The total study sample consisted of 44,415 implants shipped from Oxtein warehouses on the dates indicated, of which 917 implants (2.1%) were flagged due to reports of lack of primary stability, failed osseointegration, or implant failure within one year of placement. When analyzing incident reports, it was observed that 61.6% of incidents occurred in male patients, compared to 38.4% in female patients. The average age of patients in the reported cases was 56.12 ± 12.15 years. A statistically significant correlation was discovered between incidents of implant failure and tobacco use, diabetes, heart disease, poor oral hygiene, previous infection, poor bone quality, and bruxism (p < 0.05). A (statistically significant) higher rate of incidents was also observed in tapered, internal connection, Grade IV titanium, narrow, and short implants.

Conclusions: Analysis of these implants reveals a higher rate of complication in short, tapered, internal connection and narrow-diameter implants. These data can help and encourage clinicians to use the utmost surgical precautions when placing these implants.

Conflict of interest statement

Conflicts of interest None declared.

Figures

Figure 1
Figure 1
Images of the implants used in the present study. a) M12: Morse taper connection, aggressive tapered profile, Grade IV titanium; b) M8: Internal octagon connection, less aggressive cylindrical profile, Grade IV titanium; c) L35: Internal hexagon connection, cylindrical profile, Grade V titanium; d) L6: External hexagon connection, cylindrical profile, Grade V titanium; e) N35: Internal hexagon connection, tapered profile, Grade V titanium; f) N6: External hexagon connection, tapered profile, Grade V titanium.

References

    1. Hickin MP, Shariff JA, Jennette PJ, Finkelstein J, Papapanou PN. Incidence and Determinants of Dental Implant Failure: A Review of Electronic Health Records in a U.S. Dental School. J Dent Educ. 2017;81:1233–42.
    1. Derks J, Tomasi C. Peri-implant health and disease: a systematic review of current epidemiology. J Clin Periodontol. 2015;42:S158–71.
    1. Berglundh T, Persson L, Klinge B. A systematic review of the incidence of biological and technical complications in implant dentistry reported in prospective longitudinal studies of at least 5 years. J Clin Periodontol. 2002;29:197–212.
    1. Regulation (EU) 2017/745 of the European Parliament and of the Council of 5 April 2017 on medical devices, amending Directive 2001/83/EC, Regulation (EC) No 178/2002 and Regulation (EC) No 1223/2009 and repealing Council Directives 90/385/EEC and 93/42/EEC (Text with EEA relevance. Brussels: EUROPEAN PARLIAMENT AND OF THE COUNCIL; 2017. [5 April 2017]. [Internet] Available from: .
    1. Bryant SR, Zarb GA. Osseointegration of oral implants in older and younger adults. Int J Oral Maxillofac Implants. 1998;13:492–9.
    1. Baqain ZH, Moqbel WY, Sawair FA. Early dental implant failure: risk factors. Br J Oral Maxillofac Surg. 2012;50:239–43.
    1. Noda K, Arakawa H, Kimura-Ono A, Yamazaki S, Hara ES, Sonoyama W. A longitudinal retrospective study of the analysis of the risk factors of implant failure by the application of generalized estimating equations. J Prosthodont Res. 2015;59:178–84.
    1. Grisar K, Sinha D, Schoenaers J, Dormaar T, Politis C. Retrospective Analysis of Dental Implants Placed Between 2012 and 2014: Indications, Risk Factors, and Early Survival. Int J Oral Maxillofac Implants. 2017;32:649–54.
    1. Brocard D, Barthet P, Baysse E, Duffort JF, Eller P, Justumus P. A multicenter report on 1,022 consecutively placed ITI implants: a 7-year longitudinal study. Int J Oral Maxillofac Implants. 2000;15:691–700.
    1. Moy PK, Medina D, Shetty V, Aghaloo TL. Dental implant failure rates and associated risk factors. Int J Oral Maxillofac Implants. 2005;20:569–77.
    1. Hasegawa T, Kawabata S, Takeda D, Iwata E, Saito I, Arimoto S. Survival of Branemark System Mk III implants and analysis of risk factors associated with implant failure. Int J Oral Maxillofac Surg. 2017;46:267–73.
    1. Anitua E, Orive G, Aguirre JJ, Ardanza B, Andia I. 5-year clinical experience with BTI dental implants: risk factors for implant failure. J Clin Periodontol. 2008;35:724–32.
    1. Derks J, Schaller D, Hakansson J, et al. Effectiveness of implant therapy analyzed in a Swedish population: prevalence of peri-implantitis. J Dent Res. 2016;95:43–9.
    1. Sverzut AT, Stabile GA, de Moraes M, Mazzonetto R, Moreira RW. The influence of tobacco on early dental implant failure. J Oral Maxillofac Surg. 2008;66:1004–9.
    1. Wagenberg B, Froum SJ. A retrospective study of 1925 consecutively placed immediate implants from 1988 to 2004. Int J Oral Maxillofac Implants. 2006;21:71–80.
    1. Montes CC, Pereira FA, Thomé G, Alves ED, Acedo RV, de Souza JR. Failing factors associated with osseointegrated dental implant loss. Implant Dent. 2007;16:404–12.
    1. Olmedo-Gaya MV, Manzano-Moreno FJ, Cañaveral-Cavero E, de Dios Luna-del Castillo J, Vallecillo-Capilla M. Risk factors associated with early implant failure: A 5-year retrospective clinical study. J Prosthet Dent. 2016;115:150–5.
    1. Carr AB, Revuru VS, Lohse CM. Association of Systemic Conditions with Dental Implant Failures in 6,384 Patients During a 31-Year Follow-up Period. Int J Oral Maxillofac Implants. 2017;32:1153–61.
    1. Lin G, Ye S, Liu F, He F. A retrospective study of 30,959 implants: Risk factors associated with early and late implant loss. J Clin Periodontol. 2018;45:733–43.
    1. Andersen OZ, Offermanns V, Sillassen M, Almtoft KP, Andersen IH, Sørensen S. Accelerated bone ingrowth by local delivery of strontium from surface functionalized titanium implants. Biomaterials. 2013;34:5883–90.
    1. Gómez-de Diego R, Mang-de la Rosa M, Romero-Pérez MJ, Cutando-Soriano A, López-Valverde-Centeno A. Indications and contraindications of dental implants in medically compromised patients: Update. Med Oral Patol Oral Cir Bucal. 2014;19:e483–9.
    1. Clementini M, Rossetti PH, Penarrocha D, Micarelli C, Bonachela WC, Canullo L. Systemic risk factors for peri-implant bone loss: a systematic review and meta-analysis. Int J Oral Maxillofac Surg. 2014;43:323–34.
    1. Esposito M, Grusovin MG, Worthington HV. Interventions for replacing missing teeth: antibiotics at dental implant placement to prevent complications (review) Cochrane Library. 2013;7:1–37.
    1. Liaw K, Delfini RH, Abrahams JJ. Dental Implant Complications. Semin Ultrasound CT MR. 2015;36:427–33.
    1. Tanner A, Maiden MF, Lee K, Shulman LB, Weber HP. Dental implant infections. Clin Infect Dis. 1997;25:S213–7.
    1. Choi YG, Eckert SE, Kang KL, Shin SW, Kim YK. Epidemiology of Implant Mortality Disparity Among Intraoral Positions and Prosthesis Types. Int J Oral Maxillofac Implants. 2017;32:525–32.
    1. Scardina GA, Messina P. Oral microcirculation in post-menopause: a possible correlation with periodontitis. Gerodontology. 2012;29:e1045–51.
    1. Chrcanovic BR, Albrektsson T, Wennerberg A. Bone Quality and Quantity and Dental Implant Failure: A Systematic Review and Meta-analysis. Int J Prosthodont. 2017;30:219–37.
    1. Jemt T, Karouni M, Abitbol J, Zouiten O, Antoun H. A retrospective study on 1592 consecutively performed operations in one private referral clinic. Part II: Peri-implantitis and implant failures. Clin Implant Dent Relat Res. 2017;19:413–22.
    1. Carr AB. Implant location and radiotherapy are the only factors linked to 2-year implant failure. J Evid Based Dent Pract. 2012;12:217–9.
    1. Legami CM, Uehara PN, Sesma N, Pannuti CM, Tortamano-Neto P, Mukai MK. Survival rate of titanium-zirconium narrow diameter dental implants versus commercially pure titanium narrow diameter dental implants: A systematic review. Clin Implant Dent Relat Res. 2017;19:1015–22.
    1. Mangano F, Lucchina AG, Brucoli M, Migliario M, Mortellaro C, Mangano C. Prosthetic Complications Affecting Single-Tooth Morse-Taper Connection Implants. J Craniofac Surg. 2018;29:2255–62.
    1. Traini T, De Paoli S, Caputi S, Iezzi G, Piattelli A. Collagen fiber orientation near a fractured dental implant after a 5-year loading period: case report. Implant Dent. 2006;15:70–6.
    1. Tabrizi R, Behnia H, Taherian S, Hesami N. What are the Incidence and Factors Associated With Implant Fracture? J Oral Maxillofac Surg. 2017;75:1866–72.
    1. Baggi L, Di Girolamo M, Vairo G, Sannino G. Comparative evaluation of osseointegrated dental implants based on platform-switching concept: influence of diameter, length, thread shape, and in-bone positioning depth on stress-based performance. Comput Math Methods Med. 2013;2013:250929.
    1. Hingsammer L, Watzek G, Pommer B. The influence of crown-to-implant ratio on marginal bone levels around splinted short dental implants: A radiological and clincial short term analysis. Clin Implant Dent Relat Res. 2017;19:1090–8.
    1. Garaicoa-Pazmiño C, Suárez-López del Amo F, Monje A, Catena A, Ortega-Oller I, Galindo-Moreno P. Influence of crown/implant ratio on marginal bone loss: a systematic review. J Periodontol. 2014;85:1214–21.
    1. Cochran DL. A comparison of endosseous dental implant surfaces. J Periodontol. 1999;70:1523–39.
    1. Thoma DS, Zeltner M, Husler J, Hammerle CH, Jung RE. EAO Supplement Working Group 4 - EAO CC 2015 Short implants versus sinus lifting with longer implants to restore the posterior maxilla: a systematic review. Clin Oral Implants Res. 2015;26:154–69.
    1. Esposito M, Pistilli R, Barausse C, Felice P. Three-year results from a randomised controlled trial comparing prostheses supported by 5-mm long implants or by longer implants in augmented bone in posterior atrophic edentulous jaws. Eur J Oral Implantol. 2014;7:383–95.
    1. Alsaadi G, Quirynen M, Komárek A, van Steenberghe D. Impact of local and systemic factors on the incidence of late oral implant loss. Clin Oral Implants Res. 2008;19:670–6.
    1. Malmstrom H, Gupta B, Ghanem A, Cacciato R, Ren Y, Romanos GE. Success rate of short dental implants supporting single crowns and fixed bridges. Clin Oral Implants Res. 2016;27:1093–8.
    1. Cabrera-Domínguez J, Castellanos-Cosano L, Torres-Lagares D, Machuca-Portillo G. A Prospective Case-Control Clinical Study of Titanium-Zirconium Alloy Implants with a Hydrophilic Surface in Patients with Type 2 Diabetes Mellitus. Int J Oral Maxillofac Implants. 2017;32:1135–44.
    1. Mezzomo LA, Miller R, Triches D, Alonso F, Shinkai RS. Meta-analysis of single crowns supported by short (less than 10 mm) implants in the posterior region. J Clin Periodontol. 2014;41:191–213.
    1. Derks J, Håkansson J, Wennström JL, Tomasi C, Larsson M, Berglundh T. Effectiveness of implant therapy analyzed in a Swedish population: early and late implant loss. J Dent Res. 2015;94:44S–51S.
    1. Manzano G, Montero J, Martín-Vallejo J, Del Fabbro M, Bravo M, Testori T. Risk Factors in Early Implant Failure: A Meta-Analysis. Implant Dent. 2016;25:272–80.
    1. Maló PS, de Araújo Nobre MA, Lopes AV, Ferro AS. Retrospective cohort clinical investigation of a dental implant with a narrow diameter and short length for the partial rehabilitation of extremely atrophic jaws. J Oral Sci. 2017;59:357–63.
    1. Pieri F, Forlivesi C, Caselli E, Corinaldesi G. Narrow- (3.0 mm) Versus Standard-Diameter (4.0 and 4.5 mm) Implants for Splinted Partial Fixed Restoration of Posterior Mandibular and Maxillary Jaws: A 5-Year Retrospective Cohort Study. J Periodontol. 2017;88:338–47.
    1. Pommer B, Frantal S, Willer J, Posch M, Watzek G, Tepper G. Impact of dental implant length on early failure rates: a meta-analysis of observational studies. J Clin Periodontol. 2011;38:856–63.
    1. Klein MO, Schiegnitz E, Al-Nawas B. Systematic review on success of narrow-diameter dental implants. Int J Oral Maxillofac Implants. 2014;29:43–54.
    1. Sierra-Sánchez JL, Martínez-González A, García-Sala Bonmatí F, Mañes-Ferrer JF, Brotons-Oliver A. Narrow-diameter implants: are they a predictable treatment option? A literature review. Med Oral Patol Oral Cir Bucal. 2014;19:e74–81.
    1. Müller F, Al-Nawas B, Storelli S, Quirynen M, Hicklin S, Castro-Laza J. Small-diameter titanium grade IV and titanium-zirconium implants in edentulous mandibles: five-year results from a double-blind, randomized controlled trial. BMC Oral Health. 2015;15:123.
    1. Holmgren EP, Seckinger RJ, Kilgren LM, Mante F. Evaluating parameters of osseointegrated dental implants using finite element analysis--a two-dimensional comparative study examining the effects of implant diameter, implant shape, and load direction. J Oral Implantol. 1998;24:80–8.
    1. Saini M, Singh Y, Arora P, Arora V, Jain K. Implant biomaterials: A comprehensive review. World J Clin Cases. 2015;3:52–7.
    1. Hirata R, Bonfante EA, Machado LS, Tovar N, Coelho PG. Mechanical Evaluation of Two Grades of Titanium Used in Implant Dentistry. Int J Oral Maxillofac Implants. 2015;30:800–5.
    1. Park SJ, Lee SW, Leesungbok R, Ahn SJ. Influence of the connection design and titanium grades of the implant complex on resistance under static loading. J Adv Prosthodont. 2016;8:388–95.
    1. Ortega-Martínez J, Pérez-Pascual T, Mareque-Bueno S, Hernández-Alfaro F, Ferrés-Padró E. Immediate implants following tooth extraction. A systematic review. Med Oral Patol Oral Cir Bucal. 2012;17:e251–61.
    1. Zinser MJ, Randelzhofer P, Kuiper L, Zöller JE, De Lange GL. The predictors of implant failure after maxillary sinus floor augmentation and reconstruction: a retrospective study of 1045 consecutive implants. Oral Surg Oral Med Oral Pathol Oral Radiol. 2013;115:571–82.
    1. Olson JW, Dent CD, Morris HF, Ochi S. Long-term assessment (5 to 71 months) of endosseous dental implants placed in the augmented maxillary sinus. Ann Periodontol. 2000;5:152–6.
    1. Naert I, Koutsikakis G, Duyck J, Quirynen M, Jacobs R, van Steenberghe D. Biologic outcome of implant-supported restorations in the treatment of partial edentulism. part I: a longitudinal clinical evaluation. Clin Oral Implants Res. 2002;13:381–9.

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