Individualized positive end-expiratory pressure with and without recruitment maneuvers in obese patients during bariatric surgery

Zhi-Yao Wang, Shan-Shan Ye, Yu Fan, Cheng-Ye Shi, Hai-Fu Wu, Chang-Hong Miao, Di Zhou, Zhi-Yao Wang, Shan-Shan Ye, Yu Fan, Cheng-Ye Shi, Hai-Fu Wu, Chang-Hong Miao, Di Zhou

Abstract

This study aimed to determine whether regular recruitment maneuvers (RMs) are essential for obese patients (OPs) undergoing elective laparoscopic bariatric surgery (LBS) during intraoperative ventilation with individualized positive end-expiratory pressure (PEEP). Patients were randomly assigned to two arms: the RM + PEEP-EIT arm consisted of individualized PEEP titrated by electrical impedance tomography (EIT) with two regular RMs and the PEEP-EIT arm consisted of individualized PEEP titrated by EIT without additional RMs. For these two arms together, EIT-guided PEEP varied among individuals. The partial pressure of oxygen in arterial blood to fractional inspired oxygen (PaO2 /FiO2 ) ratio in the RM + PEEP-EIT arm was higher than that in the PEEP-EIT arm at 1 h after pneumoperitoneum (p = 0.024) and at the end of surgery (p = 0.035). There was no great difference in the PaO2 /FiO2 ratio between these two arms when measured 5 min prior to postanesthesia care unit (PACU) departure and on postoperative day 1. Compared with the PEEP-EIT arm, patients in the RM + PEEP-EIT arm had significantly higher intraoperative dynamic respiratory system compliance (p < 0.001) but consumed more vasopressors (p = 0.036). Postoperative pulmonary complications occurred in 1 of 29 patients in the RM + PEEP-EIT arm compared with 2 of 31 patients in the PEEP-EIT arm. Regular lung RMs can improve intraoperative oxygenation and respiratory system compliance among OPs undergoing LBS with EIT-guided individual PEEP. However, the improvement might disappear before leaving the PACU, and regular RMs resulted in more vasopressor consumption.

Keywords: electrical impedance tomography; laparoscope bariatric surgery; obese patients; recruitment maneuver.

© 2022 The Authors. The Kaohsiung Journal of Medical Sciences published by John Wiley & Sons Australia, Ltd on behalf of Kaohsiung Medical University.

References

REFERENCES

    1. HH B, Hedley-Whyte J, MB L. Impaired oxygenation in surgical patients during general anesthesia with controlled ventilation. A concept of atelectasis. N Engl J Med. 1963;269:991-6.
    1. Tokics L, Hedenstierna G, Strandberg A, Brismar B, Lundquist H. Lung collapse and gas exchange during general anesthesia: effects of spontaneous breathing, muscle paralysis, and positive end-expiratory pressure. Anesthesiology. 1987;66(2):157-67.
    1. Bazurro S, Ball L, Pelosi P. Perioperative management of obese patient. Curr Opin Crit Care. 2018;24(6):560-7.
    1. Andersson LE, Bååth M, Thörne A, Aspelin P, Odeberg-Wernerman S. Effect of carbon dioxide pneumoperitoneum on development of atelectasis during anesthesia, examined by spiral computed tomography. Anesthesiology. 2005;102(2):293-9.
    1. Menderes G, Gysler SM, Vadivelu N, Silasi DA. Challenges of robotic gynecologic surgery in morbidly obese patients and how to optimize success. Curr Pain Headache Rep. 2019;23(7):51.
    1. Hedenstierna G. Small tidal volumes, positive end-expiratory pressure, and lung recruitment maneuvers during anesthesia: good or bad? Anesthesiology. 2015;123(3):501-3.
    1. O'Gara B, Talmor D. Perioperative lung protective ventilation. BMJ. 2018;362:k3030.
    1. Acute Respiratory Distress Syndrome Network, Brower RG, Matthay MA, Morris A, Schoenfeld D, Thompson BT, et al. Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. N Engl J Med. 2000;342(18):1301-8.
    1. Gu WJ, Wang F, Liu JC. Effect of lung-protective ventilation with lower tidal volumes on clinical outcomes among patients undergoing surgery: a meta-analysis of randomized controlled trials. CMAJ. 2015;187(3):E101-9.
    1. Reinius H, Jonsson L, Gustafsson S, Sundbom M, Duvernoy O, Pelosi P, et al. Prevention of atelectasis in morbidly obese patients during general anesthesia and paralysis: a computerized tomography study. Anesthesiology. 2009;111(5):979-87.
    1. Ball L, Pelosi P. Positive end-expiratory pressure and recruitment maneuvers in obese patients: should we chase oxygenation? Minerva Anestesiol. 2018;84(4):429-31.
    1. Cui Y, Cao R, Li G, Gong T, Ou Y, Huang J. The effect of lung recruitment maneuvers on post-operative pulmonary complications for patients undergoing general anesthesia: a meta-analysis. PLoS One. 2019;14(5):e0217405.
    1. Frerichs I, Amato MB, van Kaam AH, Tingay DG, Zhao Z, Grychtol B, et al. Chest electrical impedance tomography examination, data analysis, terminology, clinical use and recommendations: consensus statement of the TRanslational EIT developmeNt stuDy group. Thorax. 2017;72(1):83-93.
    1. Victorino JA, Borges JB, Okamoto VN, Matos GF, Tucci MR, Caramez MP, et al. Imbalances in regional lung ventilation: a validation study on electrical impedance tomography. Am J Respir Crit Care Med. 2004;169(7):791-800.
    1. Liu K, Huang C, Xu M, Wu J, Frerichs I, Moeller K, et al. PEEP guided by electrical impedance tomography during one-lung ventilation in elderly patients undergoing thoracoscopic surgery. Ann Transl Med. 2019;7(23):757.
    1. Zhao Z, Pulletz S, Frerichs I, Müller-Lisse U, Möller K. The EIT-based global inhomogeneity index is highly correlated with regional lung opening in patients with acute respiratory distress syndrome. BMC Res Notes. 2014;7:82.
    1. He X, Jiang J, Liu Y, Xu H, Zhou S, Yang S, et al. Electrical impedance tomography-guided PEEP titration in patients undergoing laparoscopic abdominal surgery. Medicine (Baltimore). 2016;95(14):e3306.
    1. Pereira SM, Tucci MR, Morais CCA, Simões CM, Tonelotto BFF, Pompeo MS, et al. Individual positive end-expiratory pressure settings optimize intraoperative mechanical ventilation and reduce postoperative atelectasis. Anesthesiology. 2018;129(6):1070-81.
    1. Nestler C, Simon P, Petroff D, Hammermüller S, Kamrath D, Wolf S, et al. Individualized positive end-expiratory pressure in obese patients during general anaesthesia: a randomized controlled clinical trial using electrical impedance tomography. Br J Anaesth. 2017;119(6):1194-205.
    1. Wei K, Min S, Cao J, Hao X, Deng J. Repeated alveolar recruitment maneuvers with and without positive end-expiratory pressure during bariatric surgery: a randomized trial. Minerva Anestesiol. 2018;84(4):463-72.
    1. Zhao Z, Steinmann D, Frerichs I, Guttmann J, Möller K. PEEP titration guided by ventilation homogeneity: a feasibility study using electrical impedance tomography. Crit Care. 2010;14(1):R8.
    1. Littleton SW, Tulaimat A. The effects of obesity on lung volumes and oxygenation. Respir Med. 2017;124:15-20.
    1. Steier J, Lunt A, Hart N, Polkey MI, Moxham J. Observational study of the effect of obesity on lung volumes. Thorax. 2014;69(8):752-9.
    1. Fumagalli J, Berra L, Zhang C, Pirrone M, Santiago RRS, Gomes S, et al. Transpulmonary pressure describes lung morphology during Decremental positive end-expiratory pressure trials in obesity. Crit Care Med. 2017;45:1374-81.
    1. Deng QW, Tan WC, Zhao BC, Wen SH, Shen JT, Xu M. Intraoperative ventilation strategies to prevent postoperative pulmonary complications: a network meta-analysis of randomised controlled trials. Br J Anaesth. 2020;124:324-35.
    1. Guldner A, Braune A, Ball L, Silva PL, Samary C, Insorsi A, et al. Comparative effects of Volutrauma and Atelectrauma on lung inflammation in experimental acute respiratory distress syndrome. Crit Care Med. 2016;44:e854-65.
    1. Rouby JJ, Brochard L. Tidal recruitment and overinflation in acute respiratory distress syndrome: yin and yang. Am J Respir Crit Care Med. 2007;175:104-6.
    1. Hemmes SN, Gama de Abreu M, Pelosi P, Schultz MJ, Anaesthesiology PNIftCTNotESo. High versus low positive end-expiratory pressure during general anaesthesia for open abdominal surgery (PROVHILO trial): a multicentre randomised controlled trial. Lancet. 2014;384:495-503.
    1. Pelosi P, Rocco PRM, Gama de Abreu M. Close down the lungs and keep them resting to minimize ventilator-induced lung injury. Crit Care. 2018;22:72.
    1. Pelosi P, Croci M, Ravagnan I, Tredici S, Pedoto A, Lissoni A, et al. The effects of body mass on lung volumes, respiratory mechanics, and gas exchange during general anesthesia. Anesth Analg. 1998;87:654-60.
    1. Pirrone M, Fisher D, Chipman D, Imber DA, Corona J, Mietto C, et al. Recruitment maneuvers and positive end-expiratory pressure titration in morbidly obese ICU patients. Crit Care Med. 2016;44:300-7.
    1. Van Hecke D, Bidgoli JS, Van der Linden P. Does lung compliance optimization through PEEP manipulations reduce the incidence of postoperative hypoxemia in laparoscopic bariatric surgery? A Randomized Trial Obes Surg. 2019;29:1268-75.
    1. Tusman G, Bohm SH, Suarez-Sipmann F. Advanced uses of pulse oximetry for monitoring mechanically ventilated patients. Anesth Analg. 2017;124:62-71.
    1. Grassi L, Kacmarek R, Berra L. Ventilatory mechanics in the patient with obesity. Anesthesiology. 2020;132:1246-56.
    1. Costa Souza GM, Santos GM, Zimpel SA, Melnik T. Intraoperative ventilation strategies for obese patients undergoing bariatric surgery: systematic review and meta-analysis. BMC Anesthesiol. 2020;20:36.
    1. Whalen FX, Gajic O, Thompson GB, Kendrick ML, Que FL, Williams BA, et al. The effects of the alveolar recruitment maneuver and positive end-expiratory pressure on arterial oxygenation during laparoscopic bariatric surgery. Anesth Analg. 2006;102:298-305.
    1. Writing Committee for the PROBESE Collaborative Group of the PROtective VEntilation Network (PROVEnet) for the Clinical Trial Network of the European Society of Anaesthesiology, Bluth T, Serpa Neto A, Schultz MJ, Pelosi P, Gama de Abreu M, et al. Effect of intraoperative high positive end-expiratory pressure (PEEP) with recruitment maneuvers vs low PEEP on postoperative pulmonary complications in obese patients: a randomized clinical trial. JAMA. 2019;321(23):2292-305.
    1. Iwasaka H, Miyakawa H, Yamamoto H, Kitano T, Taniguchi K, Honda N. Respiratory mechanics and arterial blood gases during and after laparoscopic cholecystectomy. Can J Anaesth. 1996;43(2):129-33.
    1. Nielsen J, Nilsson M, Fredén F, Hultman J, Alström U, Kjaergaard J, et al. Central hemodynamics during lung recruitment maneuvers at hypovolemia, normovolemia and hypervolemia. A study by echocardiography and continuous pulmonary artery flow measurements in lung-injured pigs. Intensive Care Med. 2006;32(4):585-94.
    1. Ferrando C, Soro M, Unzueta C, Suarez-Sipmann F, Canet J, Librero J, et al. Individualised perioperative open-lung approach versus standard protective ventilation in abdominal surgery (iPROVE): a randomised controlled trial. Lancet Respir Med. 2018;6(3):193-203.

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