The Association of Recurrent and Multiple Types of Abuse with Adverse Mental Health, Substance Use, and Sexual Health Outcomes among Out-of-School Adolescent Girls and Young Women in Cape Town, South Africa

Bronwyn Myers, Felicia A Browne, Tara Carney, Tracy Kline, Courtney Peasant Bonner, Wendee M Wechsberg, Bronwyn Myers, Felicia A Browne, Tara Carney, Tracy Kline, Courtney Peasant Bonner, Wendee M Wechsberg

Abstract

Although physical and sexual abuse exposure is a well-established risk for poor health, the dimensions of abuse associated with health among socially vulnerable adolescent girls and young women (AGYW) remain underexamined. This article describes associations between combinations of abuse type and timing with mental health, substance use, and sexual risk outcomes among a sample of 499 AGYW (aged 16 to 19) who had left school early and were recruited for a cluster randomized trial in Cape Town, South Africa. Approximately one-third (33.5%; 95% CI: 28.7, 38.6) of participants reported lifetime abuse. Exposure to more than one type of abuse was associated with increased risk of depression (β = 3.92; 95% CI: 2.25, 5.59) and anxiety (β = 3.70; 95% CI: 2.11, 5.28), and greater odds of polydrug use (OR = 2.10; 95% CI: 1.02, 4.34) and substance-impaired sex (OR = 2.17; 95% CI: 1.31, 3.86). Exposure to multiple types of abuse during childhood/early adolescence and again in late adolescence was associated with increased risk of depression (β = 4.65; 95% CI: 3.15, 6.14), anxiety (β = 4.35; 95% CI: 2.70, 6.02), and polydrug use (OR = 2.37; 95% CI: 1.03, 5.73). Findings underscore the need for trauma-informed interventions that reduce mental health, substance use, and sexual risks among AGYW who have experienced multiple forms of abuse and recurrent abuse.

Keywords: gender-based violence; low- and middle-income countries; mental health; physical and sexual abuse; substance use; trauma-informed interventions; young women.

Conflict of interest statement

The authors declare no conflict of interest. The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript, or in the decision to publish the results.

References

    1. World Health Organization . Global Health Estimates 2015: Disease Burden by Cause, Age, Sex, by Country and by Region, 2000–2015. World Health Organization; Geneva, Switzerland: 2016.
    1. Kuringe E., Materu J., Nyato D., Majani E., Ngeni F., Shao A., Mjungu D., Mtenga B., Nnko S., Kipingili T., et al. Prevalence and correlates of depression and anxiety symptoms among out-of-school adolescent girls and young women in Tanzania: A cross-sectional study. PLoS ONE. 2019;14:e0221053. doi: 10.1371/journal.pone.0221053.
    1. Das-Munshi J., Lund C., Mathews C., Clark C., Rothon C., Stansfeld S. Mental health inequalities in adolescents growing up in post-apartheid South Africa: Cross-sectional survey, SHaW study. PLoS ONE. 2016;11:e0154478. doi: 10.1371/journal.pone.0154478.
    1. Myers B., Bantjes J., Lochner C., Mortier P., Kessler R.C., Stein D.J. Maltreatment during childhood and risk for common mental disorders among first year university students in South Africa. Soc. Psychiatry Psychiatr. Epidemiol. 2021;56:1175–1187. doi: 10.1007/s00127-020-01992-9.
    1. Plüddemann A., Morojele N., Myers B., Townsend L., Lombard C.J., Petersen-Williams P., Carney T., Nel E. The prevalence of risk for mental health problems among high school students in the Western Cape Province, South Africa. S. Afr. J. Psychol. 2014;4:30–35. doi: 10.1177/0081246313516264.
    1. Saban A., Flisher A.J., Grimsrud A., Morojele N., London. L., Williams D.R., Stein D.J. The association between substance use and common mental disorders in young adults: Results from the South African Stress and Health (SASH) survey. Pan Afr. Med. J. 2014;17:11. doi: 10.11604/pamjs.supp.2014.17.1.3328.
    1. James S., Reddy S.P., Ellahebokus A., Sewpaul R., Naidoo P. The association between adolescent risk behaviours and feelings of sadness or hopelessness: A cross-sectional survey of South African secondary school learners. Psychol. Health Med. 2017;22:778–789. doi: 10.1080/13548506.2017.1300669.
    1. Kuo C., LoVette A., Stein D.J., Cluver L.D., Brown L.K., Atujuna M., Gladstone T.R., Martin J., Beardslee W. Building resilient families: Developing family interventions for preventing adolescent depression and HIV in low resource settings. Transcult. Psychiatry. 2019;56:187–212. doi: 10.1177/1363461518799510.
    1. Wechsberg W., Myers B., Reed E., Carney T., Emanuel A.N., Browne F.A. Substance use, gender inequity, violence and sexual risk among couples in Cape Town. Cult. Health Sex. 2013;15:1221–1236. doi: 10.1080/13691058.2013.815366.
    1. Watt M.H., Myers B., Towe S.L., Meade C.S. The mental health experiences and needs of methamphetamine users in Cape Town: A mixed-methods study. S. Afr. Med. J. 2015;105:685–688. doi: 10.7196/SAMJnew.7910.
    1. Myers B., Johnson K., Lucas W., Govender R., Manderscheid R., Williams P.P., Koch J.R. South African service users′ perceptions of patient-reported outcome and experience measures for adolescent substance use treatment: A qualitative study. Drug Alcohol Rev. 2019;38:823–830. doi: 10.1111/dar.12996.
    1. Myers B., Kline L.T., Doherty A.I., Carney T., Wechsberg W.M. Perceived need for substance use treatment among young women from disadvantaged communities in Cape Town, South Africa. BMC Psychiatry. 2014;14:100. doi: 10.1186/1471-244X-14-100.
    1. Sorsdahl K., van der Westhuizen C., Neuman M., Weiss H., Myers B. Addressing the mental health needs of adolescents in South African communities: A protocol for a randomised controlled feasibility trial. Pilot Feasibility Stud. 2021;7:69. doi: 10.1186/s40814-021-00803-5.
    1. Myers B., Carney T., Wechsberg W.M. “Not on the agenda”: A qualitative study of influences on health services use among poor young women who use drugs in Cape Town, South Africa. Int. J. Drug Policy. 2016;30:52–58. doi: 10.1016/j.drugpo.2015.12.019.
    1. Myers B., Carney T., Browne F., Wechsberg W.M. Development of a trauma-informed substance use and sexual risk reduction intervention for young South African women. Patient Prefer. Adherence. 2018;12:1997–2006. doi: 10.2147/PPA.S175852.
    1. Petersen Williams P., Brooke-Sumner C., Joska J., Kruger J., Vanleeuw L., Dada S., Sorsdahl K., Myers B. Young South African women on antiretroviral therapy perceptions of a psychological counselling program to reduce heavy drinking and depression. Int. J. Environ. Res. Public Health. 2020;17:2249. doi: 10.3390/ijerph17072249.
    1. Hobkirk A.L., Watt M.H., Myers B., Skinner D., Meade C.S. A qualitative study of methamphetamine initiation in Cape Town, South Africa. Int. J. Drug Policy. 2016;30:91–106. doi: 10.1016/j.drugpo.2015.10.006.
    1. Erskine H.E., Moffitt T.E., Copeland W.E., Costello E.J., Ferrari A.J., Patton G., Degenhardt L., Vos T., Whiteford H.A., Scott J.G. A heavy burden on young minds: The global burden of mental and substance use disorders in children and youth. Psychol. Med. 2015;45:1551–1563. doi: 10.1017/S0033291714002888.
    1. Fullagar S., Rich E., Francombe-Webb J., Maturo A. Digital ecologies of youth mental health: Apps, therapeutic publics and pedagogy as affective arrangements. Soc. Sci. 2017;6:135. doi: 10.3390/socsci6040135.
    1. Ngo V.K., Rubinstein A., Ganju V., Kanellis P., Loza N., Rabadan-Diehl C., Daar A.S. Grand challenges: Integrating mental health care into the non-communicable disease agenda. PLoS Med. 2013;10:e1001443. doi: 10.1371/journal.pmed.1001443.
    1. Marinda E., Simbayi L., Zuma K., Zungu N., Moyo S., Kondlo L., Jooste S., Nadol P., Igumbor E., Dietrich C., et al. Towards achieving the 90-90-90 HIV targets: Results from the south African 2017 national HIV survey. BMC Public Health. 2020;20:1375. doi: 10.1186/s12889-020-09457-z.
    1. Abrahams N., Mhlongo S., Dunkle K., Chirwa E., Lombard C., Seedat S., Kengne A.P., Myers B., Peer N., Garcia-Moreno C., et al. Increase in HIV incidence in women exposed to rape. AIDS. 2021;35:633–642. doi: 10.1097/QAD.0000000000002779.
    1. Duby Z., Appollis T.M., Jonas K., Maruping K., Dietrich J., LoVette A., Kuo C., Vanleeuw L., Mathews C. “As a young pregnant girl…The challenges you face”: Exploring the intersection between mental health and sexual and reproductive health amongst adolescent girls and young women in South Africa. AIDS Behav. 2021;25:344–353. doi: 10.1007/s10461-020-02974-3.
    1. Goin D.E., Pearson R.M., Craske M.G., Stein A., Pettifor A., Lippman S.A., Kahn K., Neilands T.B., Hamilton E.L., Selin A., et al. Depression and incident HIV in adolescent girls and young women in HIV Prevention Trials Network 068: Targets for prevention and mediating factors. Am. J. Epidemiol. 2020;189:422–432. doi: 10.1093/aje/kwz238.
    1. Mabaso M., Sokhela Z., Mohlabane N., Chibi B., Zuma K., Simbayi L. Determinants of HIV infection among adolescent girls and young women aged 15−24 years in South Africa: A 2012 population-based national household survey. BMC Public Health. 2018;18:183. doi: 10.1186/s12889-018-5051-3.
    1. Mthiyane N., Harling G., Chimbindi N., Baisley K., Seeley J., Dreyer J., Zuma T., Birdthistle I., Floyd S., McGrath N., et al. Common mental disorders and HIV status in the context of DREAMS among adolescent girls and young women in rural KwaZulu-Natal, South Africa. BMC Public Health. 2021;21:478. doi: 10.1186/s12889-021-10527-z.
    1. Wechsberg W.M., Myers B., Kline T.L., Carney T., Browne F.A., Novak S.P. The relationship of alcohol and other drug use typologies to sex risk behaviors among vulnerable women in Cape Town, South Africa. J. AIDS Clin. Res. 2012;S1:015. doi: 10.4172/2155-6113.S1-015.
    1. Wechsberg W.M., Jones H.E., Zule W.A., Myers B.J., Browne F.A., Kaufman M.R., Luseno W., Flisher A.J., Parry C.D. Methamphetamine (“tik”) use and its association with condom use among out of school females in Cape Town, South Africa. Am. J. Drug. Alcohol Abuse. 2010;36:208–213. doi: 10.3109/00952990.2010.493592.
    1. Colizzi M., Lasalvia A., Ruggeri M. Prevention and early intervention in youth mental health: Is it time for a multidisciplinary and trans-diagnostic model for care? Int. J. Ment. Health Syst. 2020;14:23. doi: 10.1186/s13033-020-00356-9.
    1. Galagali P.M., Brooks M.J. Psychological care in low-resource settings for adolescents. Clin. Child Psychol. Psychiatry. 2020;25:698–711. doi: 10.1177/1359104520929741.
    1. Carney T., Myers B. Effectiveness of early interventions for substance-using adolescents: Findings from a systematic review and meta-analysis. Subst. Abuse Treat. Prev. Policy. 2012;7:25. doi: 10.1186/1747-597X-7-25.
    1. Brooke-Sumner C., Petersen-Williams P., Kruger J., Mahomed H., Myers B. ‘Doing more with less’: A qualitative investigation of perceptions of South African health service managers on implementation of health innovations. Health Policy Plan. 2019;34:132–140. doi: 10.1093/heapol/czz017.
    1. Sorsdahl K., Naledi T., Lund C., Levitt N.S., Joska J.A., Stein D.J., Myers B. Integration of mental health counselling into chronic disease services at the primary health care level: Formative research on dedicated versus designated strategies in the Western Cape, South Africa. J. Health Serv. Res. Policy. 2021;26:172–179. doi: 10.1177/1355819620954232.
    1. Lindert J., von Ehrenstein O.S., Grashow R., Gal G., Braehler E., Weisskopf M.G. Sexual and physical abuse in childhood is associated with depression and anxiety over the life course: Systematic review and meta-analysis. Int. J. Public Health. 2014;59:359–372. doi: 10.1007/s00038-013-0519-5.
    1. Lynch S.J., Sunderland M., Newton N.C., Chapman C. Transdiagnostic risk and protective factors for psychopathology in young people: Systematic review protocol. JMIR Res. Protoc. 2020;9:e19779. doi: 10.2196/19779.
    1. Hughes K., Bellis M.A., Hardcastle K.A., Sethi D., Butchart A., Mikton C., Jones L., Dunne M.P. The effect of multiple adverse childhood experiences on health: A systematic review and meta-analysis. Lancet Public Health. 2017;2:e356–e366. doi: 10.1016/S2468-2667(17)30118-4.
    1. Bonner C.P., Browne F.A., Ndirangu J.W., Howard B., Zule W.A., Speizer I.S., Kline T., Wechsberg W.M. Exploring the associations between physical and sexual gender-based violence and HIV among women who use substances in South Africa: The role of agency and alcohol. AIDS Care. 2019;31:1369–1375. doi: 10.1080/09540121.2019.1595512.
    1. Kidman R., Kohler H.P. Adverse childhood experiences, sexual debut and HIV testing among adolescents in a low-income high HIV-prevalence context. AIDS. 2019;33:2245–2250. doi: 10.1097/QAD.0000000000002352.
    1. Richter L., Komárek A., Desmond C., Celentano D., Morin S., Sweat M., Chariyalertsak S., Chingono A., Gray G., Mbwambo J., et al. Reported physical and sexual abuse in childhood and adult HIV risk behaviour in three African countries: Findings from Project Accept (HPTN-043) AIDS Behav. 2014;18:381–389. doi: 10.1007/s10461-013-0439-7.
    1. Myers B., McLaughlin K.A., Wang S., Blanco C., Stein D.J. Associations between childhood adversity, adult stressful life events, and past year drug use disorders in the national epidemiological study of alcohol and related conditions (NESARC) Psycho. Addict. Behav. 2014;28:1117–1126. doi: 10.1037/a0037459.
    1. Schalinski I., Teicher M.H., Nischk D., Hinderer E., Müller O., Rockstroh B. Type and timing of adverse childhood experiences differentially affect severity of PTSD, dissociative and depressive symptoms in adult inpatients. BMC Psychiatry. 2016;16:295. doi: 10.1186/s12888-016-1004-5.
    1. Adams Z.W., Moreland A., Cohen J.R., Lee R.C., Hanson R.F., Danielson C.K., Self-Brown S., Briggs E.C. Polyvictimization: Latent profiles and mental health outcomes in a clinical sample of adolescents. Psychol. Violence. 2016;6:145–155. doi: 10.1037/a0039713.
    1. Dunn E.C., Soare T.W., Raffeld M.R., Busso D.S., Crawford K.M., Davis K.A., Fisher V.A., Slopen N., Smith A.D., Tiemeier H., et al. What life course theoretical models best explain the relationship between exposure to childhood adversity and psychopathology symptoms: Recency, accumulation, or sensitive periods? Psychol. Med. 2018;48:2562–2572. doi: 10.1017/S0033291718000181.
    1. Warmingham J.M., Handley E.D., Rogosch F.A., Manly J.T., Cicchetti D. Identifying maltreatment subgroups with patterns of maltreatment subtype and chronicity: A latent class analysis approach. Child Abuse Negl. 2019;87:28–39. doi: 10.1016/j.chiabu.2018.08.013.
    1. Ziobrowski H.N., Buka S.L., Austin S.B., Sullivan A.J., Horton N.J., Simone M., Field A.E. Using latent class analysis to empirically classify maltreatment according to the developmental timing, duration, and co-occurrence of abuse types. Child Abuse Negl. 2020;107:104574. doi: 10.1016/j.chiabu.2020.104574.
    1. Wechsberg W.M., Browne F.A., Carney T., Myers B., Minnis A., MacDonald R., Ndirangu J.W., Turner L.B., Howard B.N., Rodman N. The young women′s health CoOp in Cape Town, South Africa: Study protocol for a cluster-randomised trial for adolescent women at risk for HIV. BMC Public Health. 2018;18:859. doi: 10.1186/s12889-018-5665-5.
    1. Knight K., Holcom M., Simpson D. TCU Psychosocial Functioning and Motivation Scales: Manual on Psychometric Properties. Texas Christian University; Fort Worth, TX, USA: 1998.
    1. Wechsberg W.M. Revised Risk Behavior Assessment, Part I and Part II. Research Triangle Institute; Research Triangle, NC, USA: 1998.
    1. Connor J.P., Gullo M.J., White A., Kelly A.B. Polysubstance use: Diagnostic challenges, patterns of use and health. Curr. Opin. Psychiatry. 2014;27:269–275. doi: 10.1097/YCO.0000000000000069.
    1. Wechsberg W.M., Jewkes R., Novak S.P., Kline T., Myers B., Browne F.A., Carney T., Lopez A.A.M., Parry C. A brief intervention for drug use, sexual risk behaviours and violence prevention with vulnerable women in South Africa: A randomised trial of the Women′s Health CoOp. BMJ Open. 2013;3:e002622. doi: 10.1136/bmjopen-2013-002622.
    1. Optimus Study South Africa: Technical Report. Sexual Victimization of Children in South Africa: Final Report of the Optimus Foundation Study. [(accessed on 1 October 2021)]. Available online: .
    1. Meinck F., Cluver L.D., Boyes M.E., Loening-Voysey H. Physical, emotional and sexual adolescent abuse victimisation in South Africa: Prevalence, incidence, perpetrators and locations. J. Epidemiol. Community Health. 2016;70:910–916. doi: 10.1136/jech-2015-205860.
    1. Lewis S.J., Arseneault L., Caspi A., Fisher H.L., Matthews T., Moffitt T.E., Odgers C.L., Stahl D., Teng J.Y., Danese A. The epidemiology of trauma and post-traumatic stress disorder in a representative cohort of young people in England and Wales. Lancet Psychiatry. 2019;6:247–256. doi: 10.1016/S2215-0366(19)30031-8.
    1. Benedini K.M., Fagan A.A. From child maltreatment to adolescent substance use: Different pathways for males and females? Fem. Criminol. 2020;15:147–173. doi: 10.1177/1557085118810426.
    1. McLaughlin K.A., DeCross S.N., Jovanovic T., Tottenham N. Mechanisms linking childhood adversity with psychopathology: Learning as an intervention target. Behav. Res. Ther. 2019;118:101–109. doi: 10.1016/j.brat.2019.04.008.
    1. Weissman D.G., Bitran D., Miller A.B., Schaefer J.D., Sheridan M.A., McLaughlin K.A. Difficulties with emotion regulation as a transdiagnostic mechanism linking child maltreatment with the emergence of psychopathology. Dev. Psychopathol. 2019;31:899–915. doi: 10.1017/S0954579419000348.
    1. Myers B., Carney T., Johnson K., Browne F.A., Wechsberg W.M. Service providers′ perceptions of barriers to the implementation of trauma-focused substance use services for women in Cape Town, South Africa. Int. J. Drug Policy. 2020;75:102628. doi: 10.1016/j.drugpo.2019.102628.
    1. Falb K., Tanner S., Asghar K., Souidi S., Mierzwa S., Assazenew A., Bakomere T., Mallinga P., Robinette K., Tibebu W., et al. Implementation of audio-computer assisted self-interview (ACASI) among adolescent girls in humanitarian settings: Feasibility, acceptability, and lessons learned. Confl. Health. 2016;10:32. doi: 10.1186/s13031-016-0098-1.

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