Time to Peak Weight Loss During Extended Behavioral Treatment

Meghan L Butryn, Christine C Call, Leah M Schumacher, Stephanie G Kerrigan, Evan M Forman, Meghan L Butryn, Christine C Call, Leah M Schumacher, Stephanie G Kerrigan, Evan M Forman

Abstract

Objective: This study was designed to examine the variability in timing of peak weight loss in behavioral treatment (BT), that is, when treatment participants reach their greatest amount of cumulative weight loss.

Methods: Secondary data analyses were conducted, drawing upon data from two clinical trials that provided 12 months of group-based BT, with sessions meeting less frequently in the second half of the treatment year. Weight was measured at the beginning of each treatment session.

Results: Cumulative proportions of participants reaching peak weight loss were as follows: 25.0% of study 1 and 20.0% of study 2 participants by month 4; 43.2% of study 1 and 52.2% of study 2 participants by month 6; 54.5% of study 1 and 77.8% of study 2 participants by month 8. Among participants who peaked after 4 months, the mean amount of additional weight loss achieved between 4 months and the peak session was 4.74 kg in study 1 and 4.07 kg in study 2.

Conclusions: Substantial variability in the timing of peak weight loss was observed, with larger than expected proportions of participants reaching their greatest amount of cumulative weight loss in the final months of treatment. This variability may create methodological and clinical challenges.

Trial registration: ClinicalTrials.gov NCT01854320 NCT01858714.

Conflict of interest statement

DISCLOSURE: The authors declared no conflict of interest.

© 2018 The Obesity Society.

Figures

Figure 1
Figure 1
Session at which maximum weight loss was achieved.
Figure 2
Figure 2
Weight Change (Kg) based on Time when Peak Weight Loss was Achieved

References

    1. MacLean PS, Wing RR, Davidson T, Epstein L, Goodpaster B, Hall KD, et al. NIH working group report: Innovative research to improve maintenance of weight loss. Obesity (Silver Spring) 2015;23:7–15.
    1. Jensen MD, Ryan DH, Donato KA, Apovian CM, Ard JD, Comuzzie AG, et al. Guidelines (2013) for the management of overweight and obesity in adults. Obesity (Silver Spring) 2014;22:S1–S410.
    1. Wing RR, Tate DF, Gorin AA, Raynor HA, Fava JL. A self-regulation program for maintenance of weight loss. N Engl J Med. 2006;355:1563–1571.
    1. Svetkey LP, Stevens VJ, Brantley PJ, Appel LJ, Hollis JF, Loria CM, et al. Comparison of strategies for sustaining weight loss: the weight loss maintenance randomized controlled trial. JAMA. 2008;299:1139–1148.
    1. Perri MG, Limacher MC, Durning PE, Janicke DM, Lutes LD, Bobroff LB, et al. Extended-care programs for weight management in rural communities: the treatment of obesity in underserved rural settings (TOURS) randomized trial. Arch Intern Med. 2008;168:2347–2354.
    1. Montesi L, El Ghoch M, Brodosi L, Calugi S, Marchesini G, Dalle Grave R. Long-term weight loss maintenance for obesity: a multidisciplinary approach. Diabetes Metab Syndr Obes. 2016;9:37–46.
    1. Perri MG, Nezu AM, Patti ET, McCann KL. Effect of length of treatment on weight loss. J Consult Clin Psychol. 1989;57:450–452.
    1. Ross Middleton KM, Patidar SM, Perri MG. The impact of extended care on the long-term maintenance of weight loss: a systematic review and meta-analysis. Obes Rev. 2012;13:509–517.
    1. Dombrowski SU, Knittle K, Avenell A, Araujo-Soares V, Sniehotta FF. Long term maintenance of weight loss with non-surgical interventions in obese adults: systematic review and meta-analyses of randomised controlled trials. BMJ. 2014;348:g2646.
    1. Jeffery RW, Drewnowski A, Epstein LH, Stunkard AJ, Wilson GT, Wing RR, et al. Long-term maintenance of weight loss: current status. Health Psychol. 2000;19:5–16.
    1. Butryn ML, Forman EM, Lowe MR, Gorin AA, Zhang F, Schaumberg K. Efficacy of environmental and acceptance-based enhancements to behavioral weight loss treatment: The ENACT trial. Obesity (Silver Spring) 2017;25:866–872.
    1. Forman EM, Butryn ML, Manasse SM, Crosby RD, Goldstein SP, Wyckoff EP, et al. Acceptance-based versus standard behavioral treatment for obesity: Results from the mind your health randomized controlled trial. Obesity (Silver Spring) 2016;24:2050–2056.
    1. Forman EM, Butryn ML. Effective Weight Loss: An Acceptance-Based Behavioral Approach, Clinician Guide (Treatments That Work) Oxford University Press; New York: p. 2016.
    1. Forman EM, Butryn ML, Juarascio AS, Bradley LE, Lowe MR, Herbert JD, et al. The mind your health project: a randomized controlled trial of an innovative behavioral treatment for obesity. Obesity (Silver Spring) 2013;21:1119–1126.
    1. Yuan YC. Multiple imputation for missing data: Concepts and new development. SAS Institute Inc; Rockville, MD: 2005.
    1. Neiberg RH, Wing RR, Bray GA, Reboussin DM, Rickman AD, Johnson KC, et al. Patterns of weight change associated with long-term weight change and cardiovascular disease risk factors in the look ahead study. Obesity (Silver Spring) 2012;20:2048–2056.
    1. Thomas DM, Martin CK, Redman LM, Heymsfield SB, Lettieri S, Levine JA, et al. Effect of dietary adherence on the body weight plateau: a mathematical model incorporating intermittent compliance with energy intake prescription. Am J Clin Nutr. 2014;100:787–795.
    1. Tinker LF, Rosal MC, Young AF, Perri MG, Patterson RE, Van Horn L, et al. Predictors of dietary change and maintenance in the Women’s Health Initiative Dietary Modification Trial. J Am Diet Assoc. 2007;107:1155–1166.

Source: PubMed

Sponsorer og samarbejdspartnere

Medicinske tilstande

Narkotikainterventioner

3
Abonner