Repeatability of electromyography recordings and muscle synergies during gait among children with cerebral palsy

Abstract

Background: Clinical gait analysis is commonly used in the evaluation and treatment of children with cerebral palsy (CP). While the repeatability of kinematic and kinetic measures of gait has previously been evaluated, the repeatability of electromyography (EMG) recordings or measures calculated from EMG data, such as muscle synergies, remains unclear for this population.

Research question: Are EMG recordings and muscle synergies from clinical gait analysis repeatable between visits for children with CP?

Methods: We recruited 20 children with bilateral CP who had been referred for clinical gait analysis. The children completed two visits less than six weeks apart with EMG data collected bilaterally from five muscles (rectus femoris, medial hamstrings, vastus lateralis, anterior tibialis, and medial gastrocnemius). Variance ratio and cosine similarity were used to evaluate repeatability of EMG waveforms between visits. Nonnegative matrix factorization was used to calculate synergies from EMG data at each visit to compare synergy weights and activations.

Results & significance: The inter-visit variance ratios of EMG data for children with CP were similar to previously reported results for typically-developing children and unimpaired adults (range: 0.39 for vastus lateralis to 0.66 for rectus femoris). The average cosine similarity of the EMG waveforms between visits was greater than 0.9 for all muscles, while synergy weights and activations also had high similarity - greater than 0.8 and 0.9 between visits, respectively. These results demonstrate that EMG repeatability between visits during clinical gait analysis for children with CP is similar to unimpaired individuals. These results provide a baseline for evaluating whether observed changes in EMG recordings between visits reflect real changes in muscle activity or are within the range of inter-visit variability.

Keywords: Clinical gait analysis; Inter-day reliability; Minimal detectable change; Motor modules; Walking.

Conflict of interest statement

Conflicts of Interest Statement:

The authors have no conflicts of interest to disclose related to this work.

Declarations of Interest: None

Copyright © 2018 Elsevier B.V. All rights reserved.

Figures

Figure 1.

Example of EMG data and muscle synergies of all gait cycles for each visit from the right leg of one participant. EMG data were collected from five muscles from each leg and normalized to the gait cycle to evaluate intra-visit and inter-visit repeatability. EMG data from all gait cycles were concatenated and NNMF was used to calculate synergies. For this participant, three synergies were required to describe over 95% of the variance in EMG data on the right leg at both visits with a similarity of 0.91 and 0.95 for synergy weights and activations, respectively.

Figure 2.

(Top) Average intra-visit and inter-visit cosine similarity of EMG data and synergies across all participants. (Middle) The total variance accounted for by a given number of synergies (tVAFn) at each visit. (Bottom) Average cosine similarity of synergy weights and activations between visits across all participants. The averages of the right and left legs are shown.