PERson-centredness in Hypertension management using Information Technology: a randomized controlled trial in primary care

Ulrika Andersson, Peter M Nilsson, Karin Kjellgren, Mikael Hoffmann, André Wennersten, Patrik Midlöv, Ulrika Andersson, Peter M Nilsson, Karin Kjellgren, Mikael Hoffmann, André Wennersten, Patrik Midlöv

Abstract

Objectives: To increase the proportion of individuals with hypertension obtaining a blood pressure (BP) of less than 140/90 mmHg by improving the management of hypertension in daily life from a person-centred perspective.

Methods: In this unblinded randomized controlled trial, we tested an interactive web-based self-management system for hypertension. A total of 949 patients with hypertension from 31 primary healthcare centres (PHCCs) in Sweden were randomized 1 : 1 to either the intervention or usual care group. The intervention included daily measurement - via the participant's mobile phone - of BP and pulse and reports of well being, symptoms, lifestyle, medication intake and side effects for eight consecutive weeks. It also included reminders and optional motivational messages. The primary outcome was the proportion of participants obtaining BP of less than 140/90 mmHg at 8 weeks and 12 months. Significance was tested by Pearson's chi 2 -test.

Results: A total of 862 patients completed the trial, 442 in the intervention group and 420 in the control group. The primary outcome (BP <140/90 mmHg) at 8 weeks was achieved by 48.8% in the intervention group and 39.9% in the control group ( P = 0.006). At 12 months, 47.1% (intervention) and 41.0% (control group) had a BP less than 140/90 mmHg ( P = 0.071).

Conclusion: The proportion of participants with a controlled BP of less than 140/90 mmHg increased after using the interactive system for self-management of hypertension for 8 weeks compared with usual care. Although the trend continued, there was no significant difference after 12 months. The results indicate that the effect of the intervention is significant, but the long-term effect is uncertain.

Trial registration: The study was registered with ClinicalTrials.gov (NCT03554382).

Conflict of interest statement

There are no conflicts of interest.

Copyright © 2022 The Author(s). Published by Wolters Kluwer Health, Inc.

Figures

FIGURE 1
FIGURE 1
Example of an authentic graph displaying SBP in relation to physical activity. Data from [7]. The patient can choose, which data they want to be presented, and thereby see how, for example, physical activity, stress and medication intake affects their blood pressure.
FIGURE 2
FIGURE 2
Flowchart of the PERHIT-trial. HCP, Healthcare professional. ∗Other reasons for exclusion: error in randomization, hospitalized, bad internet connection, mobile phone not working. ∗∗Other reasons for exclusion: PHCC did not complete the study, deceased, not visiting PHCC because of pandemic, were not called, unknown, spouse deceased, not been able to come to PHCC, illness. PHCC, primary healthcare centre.

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Source: PubMed

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