Outcome of a session of extracorporeal shock wave lithotripsy before endoscopic retrograde cholangiopancreatography for problematic and large common bile duct stones

Tao Tao, Ming Zhang, Qi-Jie Zhang, Liang Li, Tao Li, Xiao Zhu, Ming-Dong Li, Gui-Hua Li, Shu-Xia Sun, Tao Tao, Ming Zhang, Qi-Jie Zhang, Liang Li, Tao Li, Xiao Zhu, Ming-Dong Li, Gui-Hua Li, Shu-Xia Sun

Abstract

Aim: To compare the efficacy of a session of extracorporeal shock wave lithotripsy (ESWL) before endoscopic retrograde cholangiopancreatography (ERCP) vs ERCP only for problematic and large common bile duct (CBD) stones.

Methods: Adult patients with CBD stones for whom initial ERCP was unsuccessful because of the large size of CBD stones were identified. The patients were randomized into two groups, an "ESWL + ERCP group" and an "ERCP-only" group. For ESWL + ERCP cases, ESWL was performed prior to ERCP. Clearance of the CBD, complications related to the ESWL/ERCP procedure, frequency of mechanical lithotripsy use and duration of the ERCP procedure were evaluated in both groups.

Results: There was no significant difference in baseline characteristics between the two groups. A session of ESWL before ERCP compared with ERCP only resulted in similar outcomes in terms of successful stone removal within the first treatment session (74.2% vs 71.0%, P = 0.135), but a higher clearance rate within the second treatment session (84.4% vs 51.6%, P = 0.018) and total stone clearance (96.0% vs 86.0%, P = 0.029). Moreover, ESWL prior to ERCP not only reduced ERCP procedure time (43 ± 21 min vs 59 ± 28 min, P = 0.034) and the rate of mechanical lithotripsy use (20% vs 30%, P = 0.025), but also raised the clearance rate of extremely large stones (80.0% vs 40.0%, P = 0.016). Post-ERCP complications were similar for the two groups.

Conclusion: Based on the higher rate of successful stone removal and minimal complications, ESWL prior to ERCP appears to be a safe and effective treatment for the endoscopic removal of problematic and large CBD stones.

Keywords: Common bile duct stones; Endoscopic retrograde cholangiopancreatography; Extracorporeal shock wave lithotripsy.

Conflict of interest statement

Conflict-of-interest statement: No potential conflicts of interest relevant to this article are reported.

Figures

Figure 1
Figure 1
Large stones in the common bile duct were cracked by extracorporeal shock wave lithotripsy (A) and cleared by following endoscopic retrograde cholangiopancreatography (B and C), common bile duct strictures were dilated using a balloon, and passage dilating catheters were used to retrieve the stones (D).
Figure 2
Figure 2
Common bile duct stone clearance was assessed after each endoscopic retrograde cholangiopancreatography session using procedure reports, plain films, endoscopic retrograde cholangiopancreatography films and/or abdominal magnetic resonance cholangiopancreatography. A: Pre-ESWL large common bile duct stones were very large; B: Post-ESWL reduction in diameter of CBD stones; C: Stones were tracked by a basket during the following ERCP; D: CBD was cleared successfully. ESWT: Extracorporeal shockwave lithotripsy; ERCP: Endoscopic retrograde cholangiopancreatography; CBD: Common bile duct.

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Source: PubMed

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