Associate Scientist/Scientist - Screening, Biosensors

Associate Scientist/Scientist - Screening, Biosensors Req ID #:  92533 Location: 

S. San Francisco, CA, US, 94080 For 70 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we’ll help you build a career that you can feel passionate about. Job Summary Charles River Labs isseeking a skilled and highly motivated Associate Scientist/Scientist to join our Screening Team. The candidate will participate as a team-player by supporting a variety of projects at every stage by providing kinetic and epitope information for antibody therapeutics. The role will enable our company’s continued growth into client partnered antibody discovery services, as well as the development of internal therapeutic portfolio. Distributed Bio is a computational immunoengineering biotechnology group providing computational tools, antibody libraries, and more to partners across the pharmaceutical industry. Our mission is to disrupt biologic engineering with big data, machine learning, and computational immunology-driven design. Be part of the new paradigm in antibody engineering.

Role Responsibilities Run high-throughput kinetic and epitope binning screens on various biosensor platforms Performed high-resolution kinetics and affinity analysis of antibody-antigen binding and other protein interactions QC reagents for downstream application Design and analyze experiments under minimal supervision Present data in written and oral form to internal teams and/or our partnered clients

Job Qualifications

Requirements Bachelors (minimum 5 years) and/or Masters (minimum 0-2 years) degree in Biochemistry, Biophysics, Chemistry, Biology, Chemical Engineering or related field Previous hands-on experience with biosensor platforms (Biacore SPR, ForteBio Octet, Carterra LSA, etc.) is preferred Strong analytical and solid math skills are required Ability to perform mathematical calculations and complex data analysis tasks Previous experience with automated laboratory instrumentation is a plus Strong attention to detail and excellent bench skills Excellent time management and organizational skills Desire to work in a fast-paced, high-volume, deadline-oriented environment Strong communication (written and verbal) skills

About Discovery

Discovery from Charles River is industry-proven in the successful development of novel therapies, with over 320 patents and 74 preclinical drug candidates delivered to our sponsors in the past 17 years. Backed by more than 650 scientists, our comprehensive, integrated portfolio employs the latest technology and platforms to provide chemistry, biology, and pharmacology services that support clients from the earliest stages of hit identification all the way through to IND. Our client-focused, collaborative approach creates true partnerships that anticipate challenges, overcome obstacles, and move us forward together on the journey of getting new drugs to market.

About Charles River

Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.

With over 17,000 employees within 90 facilities in 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world. And in 2019, revenue increased to $2.62 billion.

At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of ~85% of the drugs approved by the FDA in 2019.

Equal Employment Opportunity

Charles River Laboratories is an Equal Opportunity Employer - M/F/Disabled/Vet.

If you are interested in applying to Charles River Laboratories and need special assistance or an accommodation due to a disability to complete any forms or to otherwise participate in the resume submission process, please contact a member of our Human Resources team by sending an e-mail message to crrecruitment_US@crl.com. This contact is for accommodation requests for individuals with disabilities only and cannot be used to inquire about the status of applications.

For more information, please visit www.criver.com.

Nearest Major Market: San Francisco

Nearest Secondary Market: Oakland

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